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1. 发明授权

US08837798B2 Signal and image analysis method and ultrasound imaging system 有权
标题翻译：信号和图像分析方法和超声成像系统
公开(公告)号：US08837798B2
公开(公告)日：2014-09-16
申请号：US13553793
申请日：2012-07-19
申请人： Arvin Huang-Te Li , Yio-Wha Shau , Yu-Ching Chang , Bai-Kuang Hwang , Min Shih
发明人： Arvin Huang-Te Li , Yio-Wha Shau , Yu-Ching Chang , Bai-Kuang Hwang , Min Shih
IPC分类号： G06K9/00 , G06K9/46
CPC分类号： A61B8/06 , A61B8/488 , A61B8/5223
摘要： A time domain signal analysis method is provided. The signal analysis method includes the following steps. A signal to be analyzed is received. The signal to be analyzed is iteratively sifted by using Empirical Mode Decomposition (EMD) to extract at least one intrinsic function (IMF). A normalized Hilbert transform is performed on the IMF. The transformed IMF includes phase information. The transformed IMF is processed by means of phase processing to obtain the processed IMF including angular frequency information. The foregoing signal analysis method could be utilized in an ultrasound imaging system to identify image information of ultrasound images.
摘要翻译：提供了时域信号分析方法。信号分析方法包括以下步骤。接收待分析的信号。通过使用经验模式分解（EMD）来提取至少一个内在函数（IMF）来迭代地筛选待分析的信号。在IMF上执行归一化希尔伯特变换。经转换的IMF包括阶段信息。通过相位处理来处理变换的IMF，以获得包括角频率信息的经处理的IMF。上述信号分析方法可用于超声成像系统中以识别超声图像的图像信息。

2. 发明授权

US08795678B2 TLR-2 agonists and methods of use thereof 有权
标题翻译： TLR-2激动剂及其使用方法
公开(公告)号：US08795678B2
公开(公告)日：2014-08-05
申请号：US13470554
申请日：2012-05-14
申请人： Shu-Mei Liang , Yu-Ching Chang
发明人： Shu-Mei Liang , Yu-Ching Chang
IPC分类号： A61K39/39 , A61K39/145 , A61K39/295
CPC分类号： A61K39/145 , A61K39/12 , A61K39/39 , A61K2039/55516 , A61K2039/6075 , C12N2760/16134 , C12N2770/32122
摘要： Two new TLR2 agonists, VP1 and VP3, which are structural proteins of FMDV. Residues of VP3 responsible for TLR2 activation are identified. In vivo experiments showed that VP3-4xM2e is active as a vaccine adjuvant.
摘要翻译：两种新的TLR2激动剂，VP1和VP3，它们是FMDV的结构蛋白。鉴定出负责TLR2活化的VP3残基。体内实验表明VP3-4xM2e作为疫苗佐剂是有活性的。

3. 发明申请

US20130029476A1 DICING PROCESS AND DICING APPARATUS 审中-公开
标题翻译：定义流程和定位设备
公开(公告)号：US20130029476A1
公开(公告)日：2013-01-31
申请号：US13540781
申请日：2012-07-03
申请人： Chien-Sen WENG , Mong-Yeng Xing , Yu-Ching Chang , Wei-Chang Yu , Yao-Hui Lin
发明人： Chien-Sen WENG , Mong-Yeng Xing , Yu-Ching Chang , Wei-Chang Yu , Yao-Hui Lin
IPC分类号： H01L21/78
CPC分类号： B28D5/0011 , B28D5/0052 , Y02P80/30
摘要： A dicing process is provided for cutting a wafer along a plurality of predetermined scribe lines into a plurality of dies that are releasably adhered to a release film. The dicing process includes: (a) disposing a wafer-breaking carrier on a supporting device, the wafer-breaking carrier having a chipping unit; (b) disposing the wafer above the supporting device such that the chipping unit is at a position corresponding to the scribe lines; and (c) adhering a release surface of the release film to the wafer by applying a force to the release film to contact the chipping unit of the wafer-breaking carrier with the wafer, such that the wafer is split along the scribe lines into the dies.
摘要翻译：提供了一种切割工艺，用于沿着多条预定划线将晶片切割成可剥离地粘附到脱模膜上的多个模具。切割工艺包括：（a）在支撑装置上设置晶片破坏载体，晶片断开载体具有切屑单元; （b）将所述晶片设置在所述支撑装置上方，使得所述切屑单元处于与所述划线对应的位置; 并且（c）通过向剥离膜施加力使脱模膜的释放表面附着到晶片上，以将晶片破坏载体的切屑单元与晶片接触，使得晶片沿着划线分裂成死了

4. 发明授权

US08014956B2 MicroRNA precursors 有权
标题翻译：微RNA前体
公开(公告)号：US08014956B2
公开(公告)日：2011-09-06
申请号：US11617042
申请日：2006-12-28
申请人： Yu-Ching Chang , Yu-Yu Lin , Shiu-Chieh Lan , Cheng-Tao Wu , Chung-Cheng Liu
发明人： Yu-Ching Chang , Yu-Yu Lin , Shiu-Chieh Lan , Cheng-Tao Wu , Chung-Cheng Liu
IPC分类号： G06F7/00
CPC分类号： C12N15/111 , C12N2310/14 , C12N2320/11 , C12N2330/10 , G06F19/16 , G06F19/18 , G06F19/22
摘要： Disclosed are methods of identifying microRNA motifs or microRNA precursors for a target gene or a set of target genes. Also disclosed are related computer-readable media.
摘要翻译：公开了鉴定靶基因或一组靶基因的微小RNA基序或微小RNA前体的方法。还公开了相关的计算机可读介质。

5. 发明申请

US20080231621A1 LIQUID CRYSTAL DISPLAY APPARATUS, BACKLIGHT MODULE AND LIGHT SOURCE DRIVING DEVICE THEREOF 审中-公开
标题翻译：液晶显示装置，背光模组及其光源驱动装置
公开(公告)号：US20080231621A1
公开(公告)日：2008-09-25
申请号：US12027891
申请日：2008-02-07
申请人： Yu-Ching CHANG , Jyun-Hong CHEN
发明人： Yu-Ching CHANG , Jyun-Hong CHEN
IPC分类号： G06F3/038 , G09G3/36
CPC分类号： G09G3/342 , G09G2320/041 , G09G2320/064
摘要： A light source driving device for driving a plurality of light-emitting units includes a power supply unit and a feedback control unit. The power supply unit is electrically connected to the light-emitting units and outputs a driving signal for driving the light-emitting units. The feedback control unit is electrically connected to the power supply unit and between any two light-emitting units, and retrieves a feedback signal from the light-emitting units to generate a pulse width modulation (PWM) signal for controlling the light-emitting units.
摘要翻译：用于驱动多个发光单元的光源驱动装置包括电源单元和反馈控制单元。电源单元电连接到发光单元，并输出用于驱动发光单元的驱动信号。反馈控制单元电连接到电源单元和任何两个发光单元之间，并且从发光单元检索反馈信号以产生用于控制发光单元的脉宽调制（PWM）信号。

6. 发明授权

US07397643B2 Protection circuit 失效
标题翻译：保护电路
公开(公告)号：US07397643B2
公开(公告)日：2008-07-08
申请号：US11334412
申请日：2006-01-19
申请人： Yu-Ching Chang , Ming-Chia Wu , Chung-Jung Kuo
发明人： Yu-Ching Chang , Ming-Chia Wu , Chung-Jung Kuo
IPC分类号： H02H3/20
CPC分类号： H02H3/20 , H02H3/066
摘要： A protection circuit is coupled between a secondary winding of a transformer and a load. When voltage at the secondary winding of the transformer becomes abnormal, the protection circuit disconnects the power connection to the load so as to protect the load from damage. When the voltage at the secondary winding of the transformer returns normal, the protection circuit restores power to the load.
摘要翻译：保护电路耦合在变压器的次级绕组和负载之间。当变压器次级绕组的电压异常时，保护电路断开与负载的电源连接，以保护负载免受损坏。当变压器次级绕组的电压恢复正常时，保护电路恢复负载的电力。

7. 发明申请

US20070218479A1 MicroRNA Precursors 有权
标题翻译：微RNA前体
公开(公告)号：US20070218479A1
公开(公告)日：2007-09-20
申请号：US11617042
申请日：2006-12-28
申请人： Yu-Ching Chang , Yu-Yu Lin , Shiu-Chieh Lan , Cheng-Tao Wu , Chung-Cheng Liu
发明人： Yu-Ching Chang , Yu-Yu Lin , Shiu-Chieh Lan , Cheng-Tao Wu , Chung-Cheng Liu
IPC分类号： C12Q1/68 , G06F19/00
CPC分类号： C12N15/111 , C12N2310/14 , C12N2320/11 , C12N2330/10 , G06F19/16 , G06F19/18 , G06F19/22
摘要： Disclosed are methods of identifying microRNA motifs or microRNA precursors for a target gene or a set of target genes. Also disclosed are related computer-readable media
摘要翻译：公开了鉴定靶基因或一组靶基因的微小RNA基序或微小RNA前体的方法。还公开了相关的计算机可读介质

8. 发明授权

US08744128B2 Imaging system and image processing method thereof 有权
标题翻译：成像系统及其图像处理方法
公开(公告)号：US08744128B2
公开(公告)日：2014-06-03
申请号：US13558362
申请日：2012-07-26
申请人： Arvin Huang-Te Li , Yio-Wha Shau , Yu-Ching Chang , Bai-Kuang Hwang
发明人： Arvin Huang-Te Li , Yio-Wha Shau , Yu-Ching Chang , Bai-Kuang Hwang
IPC分类号： G06K9/00 , A61B8/00
CPC分类号： A61B8/5207 , A61B8/08 , A61B8/461 , A61B8/5215
摘要： An image processing method is provided. The image processing method includes the following steps. A plurality of raw signal is received by a signal transceiving module of the ultrasound imaging system. It is determined whether each of the raw signals satisfies any condition in a condition group, and the raw signal satisfying any condition in the condition group is mapped to one of a plurality of preset constants to generate a plurality of first data. The raw signals not satisfying any condition in the condition group are processed according to a calculation formula to generate a plurality of second data. A beamforming procedure is simultaneously performed on the first and second data to obtain a beamformed image. The beamformed image is transformed to obtain an image of a region to be detected. Furthermore, an imaging system using the foregoing image processing method is also provided.
摘要翻译：提供了图像处理方法。图像处理方法包括以下步骤。多个原始信号由超声波成像系统的信号收发模块接收。确定每个原始信号是否满足条件组中的任何条件，并且满足条件组中的任何条件的原始信号被映射到多个预设常数中的一个以产生多个第一数据。根据计算公式处理条件组中不满足任何条件的原始信号，以生成多个第二数据。对第一和第二数据同时执行波束形成过程以获得波束形成的图像。波束形成的图像被变换以获得要检测的区域的图像。此外，还提供了使用上述图像处理方法的成像系统。

9. 发明申请

US20130336975A1 ANTI-NGF COMPOSITIONS AND USE THEREOF 有权
标题翻译：抗NGF组合物及其用途
公开(公告)号：US20130336975A1
公开(公告)日：2013-12-19
申请号：US13833338
申请日：2013-03-15
申请人： Benjamin H. Dutzar , Brian R. Kovacevich , Patricia Dianne McNeill , Danielle M. Mitchell , Ethan W. Ojala , Pei Fan , Jens Billgren , Erica A. Stewart , Corinne C. Akatsuka , Betty Yu-Ching Chang , John A. Latham , Leon F. Garcia-Martinez
发明人： Benjamin H. Dutzar , Brian R. Kovacevich , Patricia Dianne McNeill , Danielle M. Mitchell , Ethan W. Ojala , Pei Fan , Jens Billgren , Erica A. Stewart , Corinne C. Akatsuka , Betty Yu-Ching Chang , John A. Latham , Leon F. Garcia-Martinez
IPC分类号： C07K16/22
CPC分类号： C07K16/22 , A61K39/3955 , A61K2039/505 , C07K16/2875 , C07K2317/24 , C07K2317/41 , C07K2317/55 , C07K2317/565 , C07K2317/622 , C07K2317/76 , C07K2317/94
摘要： The present invention is directed to antibodies and fragments thereof having binding specificity for NGF. Another embodiment of this invention relates to the antibodies described herein, and binding fragments thereof, comprising the sequences of the VH, VL and CDR polypeptides described herein, and the polynucleotides encoding them. The invention also contemplates conjugates of anti-NGF antibodies and binding fragments thereof conjugated to one or more functional or detectable moieties. The invention also contemplates methods of making said anti-NGF antibodies and binding fragments thereof. Embodiments of the invention also pertain to the use of anti-NGF antibodies, and binding fragments thereof, for the diagnosis, assessment and treatment of diseases and disorders associated with NGF.
摘要翻译：本发明涉及对NGF具有结合特异性的抗体及其片段。本发明的另一个实施方案涉及本文所述的抗体及其结合片段，其包含本文所述的VH，VL和CDR多肽的序列，以及编码它们的多核苷酸。本发明还考虑了抗NGF抗体和与一个或多个功能或可检测部分缀合的结合片段的缀合物。本发明还考虑制备所述抗NGF抗体及其结合片段的方法。本发明的实施方案还涉及抗NGF抗体及其结合片段用于诊断，评估和治疗与NGF相关的疾病和病症的用途。

10. 发明授权

US07941278B2 MicroRNA motifs 有权
标题翻译：微RNA图案
公开(公告)号：US07941278B2
公开(公告)日：2011-05-10
申请号：US11617038
申请日：2006-12-28
申请人： Yu-Ching Chang , Yu-Yu Lin , Shiu-Chieh Lan , Cheng-Tao Wu , Chung-Cheng Liu
发明人： Yu-Ching Chang , Yu-Yu Lin , Shiu-Chieh Lan , Cheng-Tao Wu , Chung-Cheng Liu
IPC分类号： G06F7/00
CPC分类号： C12N15/111 , C12N2310/14 , C12N2320/11 , C12N2330/10 , G06F19/16 , G06F19/18 , G06F19/22
摘要： Disclosed are methods of identifying microRNA motifs or microRNA precursors for a target gene or a set of target genes. Also disclosed are related computer-readable media.
摘要翻译：公开了鉴定靶基因或一组靶基因的微小RNA基序或微小RNA前体的方法。还公开了相关的计算机可读介质。

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