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1. 发明申请

US20120183620A1 MESOPOROUS DRUG DELIVERY SYSTEM USING AN ELECTRICALLY CONDUCTIVE POLYMER 审中-公开
标题翻译：使用电导体聚合物的异种药物输送系统
公开(公告)号：US20120183620A1
公开(公告)日：2012-07-19
申请号：US13381201
申请日：2010-06-30
申请人： Youngnam Cho , Riyi Shi , Albena Ivanisevic , Richard Borgens
发明人： Youngnam Cho , Riyi Shi , Albena Ivanisevic , Richard Borgens
IPC分类号： A61K9/14 , C25D1/08 , A61K38/18 , A61P25/00 , B82Y5/00
CPC分类号： H01B1/127 , A61K9/0009 , C08G2261/3221 , C08L65/00
摘要： The present application relates to Nanoparticle bioengineering techniques were used to produce a non-toxic polypyrrole composition having two-dimensional and three-dimensional structures that can optionally be co-polymerized with carboxylic acid moieties to possess hydrophilicity. Likewise, such polypyrrole/carboxylic acid structures may be further modified with neural growth factors to create treatment surfaces that can promote growth an differentiation of cells such as neurons.
摘要翻译：本申请涉及纳米颗粒生物工程技术，用于生产具有二维和三维结构的无毒聚吡咯组合物，其可任选地与羧酸部分共聚以具有亲水性。同样地，这种聚吡咯/羧酸结构可以用神经生长因子进一步修饰，以产生可促进细胞如神经元分化的生长的治疗表面。

2. 发明申请

US20110052713A1 REPAIRING DAMAGED NERVOUS SYSTEM TISSUE WITH NANOPARTICLES 审中-公开
标题翻译：用纳米颗粒修复损伤的神经系统组织
公开(公告)号：US20110052713A1
公开(公告)日：2011-03-03
申请号：US12863357
申请日：2009-01-16
申请人： Youngnam Cho , Riyi Shi , Albena Ivanslevic , Richard Borgens
发明人： Youngnam Cho , Riyi Shi , Albena Ivanslevic , Richard Borgens
IPC分类号： A61K9/14 , A61K33/00 , A61K31/722 , A61K33/42 , A61P25/00
CPC分类号： A61K31/77 , A61K31/502 , A61K47/6923
摘要： The present application relates to reduction of acrolein-mediated cell death following neural insult. According to at least one embodiment, chitosan is utilized as a membrane fusogen to restore cell function. According to at least one other embodiment, chitosan or silica is used to create a non-toxic polymer surfaced microcolloid (PSM). PSMs were found to preferentially target the damaged nerve tissues; to restore conduction of nerve impulses; to seal/restore nerve fiber membranes; and to reduce to baseline the efflux of a large intracellular enzyme. PSMs are further used as a drug delivery vehicle for acrolein scavengers including hydralazine.
摘要翻译：本申请涉及神经损伤后丙烯醛介导的细胞死亡的减少。根据至少一个实施方案，壳聚糖用作膜融合蛋白以恢复细胞功能。根据至少一个其它实施方案，使用壳聚糖或二氧化硅来产生无毒的聚合物表面微胶体（PSM）。发现PSM优先靶向损伤的神经组织; 恢复神经冲动的传导; 密封/恢复神经纤维膜; 并减少到大量细胞内酶的流出基线。 PSM还被用作包括肼屈嗪在内的丙烯醛清除剂的药物递送载体。

3. 发明申请

US20090152845A1 STRUCTURE OF DRIVER'S AIRBAG CUSHION OF VEHICLE 有权
标题翻译：驾驶员安全气囊车架结构
公开(公告)号：US20090152845A1
公开(公告)日：2009-06-18
申请号：US12324379
申请日：2008-11-26
申请人： Youngnam CHO
发明人： Youngnam CHO
IPC分类号： B60R21/16
CPC分类号： B60R21/231 , B60R2021/23533
摘要： A structure for a driver's airbag cushion of a vehicle is provided to protect the driver's lower body as well as the driver's upper body and head, without mounting a knee airbag at the lower portion of the crash pad. The structure may include a blocking member that extends from a rear upper end of an airbag cushion to a front end of the airbag cushion and divides the interior of the airbag cushion into a face chamber defined by a front upper space of the airbag cushion and a pelvis chamber defined by a lower space thereof, the blocking member blocks the face and pelvis chambers, a temporary blocking member provided at a predetermined portion of the blocking member to control fluid-communication between the face chamber and the pelvis chamber when a tensile force is applied thereto, and/or a tensile force-providing member that applies tensile force to the temporary blocking member so that the pelvis chamber may be communicated with the face chamber by releasing the temporary blocking member when the pelvis chamber substantially expands.
摘要翻译：提供了用于车辆的驾驶员安全气囊垫的结构，用于保护驾驶员的下身以及驾驶员的上身和头部，而不将膝盖安全气囊安装在防撞垫的下部。该结构可以包括从气囊垫的后上端延伸到气囊垫的前端的阻挡构件，并将气囊垫的内部分成由气囊垫的前上部空间限定的面室，由其下部空间限定的骨盆室，阻塞构件阻挡面部和骨盆腔，设置在阻挡构件的预定部分处的临时阻挡构件，以在拉伸力为约束力时控制面腔和骨盆室之间的流体连通以及/或张力提供构件，其对临时阻挡构件施加张力，使得当骨盆室基本上膨胀时，通过释放临时阻挡构件，骨盆室可与面腔连通。

4. 发明授权

US07762576B2 Structure of driver's airbag cushion of vehicle 有权
标题翻译：车辆驾驶员安全气囊的结构
公开(公告)号：US07762576B2
公开(公告)日：2010-07-27
申请号：US12324379
申请日：2008-11-26
申请人： Youngnam Cho
发明人： Youngnam Cho
IPC分类号： B60R21/233 , B60R21/26
CPC分类号： B60R21/231 , B60R2021/23533
摘要： A structure for a driver's airbag cushion of a vehicle is provided to protect the driver's lower body as well as the driver's upper body and head, without mounting a knee airbag at the lower portion of the crash pad. The structure may include a blocking member that extends from a rear upper end of an airbag cushion to a front end of the airbag cushion and divides the interior of the airbag cushion into a face chamber defined by a front upper space of the airbag cushion and a pelvis chamber defined by a lower space thereof, the blocking member blocks the face and pelvis chambers, a temporary blocking member provided at a predetermined portion of the blocking member to control fluid-communication between the face chamber and the pelvis chamber when a tensile force is applied thereto, and/or a tensile force-providing member that applies tensile force to the temporary blocking member so that the pelvis chamber may be communicated with the face chamber by releasing the temporary blocking member when the pelvis chamber substantially expands.
摘要翻译：提供了用于车辆的驾驶员安全气囊垫的结构，用于保护驾驶员的下身以及驾驶员的上身和头部，而不将膝盖安全气囊安装在防撞垫的下部。该结构可以包括从气囊垫的后上端延伸到气囊垫的前端的阻挡构件，并将气囊垫的内部分成由气囊垫的前上部空间限定的面室，由其下部空间限定的骨盆室，阻塞构件阻挡面部和骨盆腔，设置在阻挡构件的预定部分处的临时阻挡构件，以在拉伸力为约束力时控制面腔和骨盆室之间的流体连通以及/或张力提供构件，其对临时阻挡构件施加张力，使得当骨盆室基本上膨胀时，通过释放临时阻挡构件，骨盆室可与面腔连通。

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