专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US09202009B2 Diagnostic support apparatus for diabetes and computer program product 有权
标题翻译：糖尿病诊断支持仪器和计算机程序产品
公开(公告)号：US09202009B2
公开(公告)日：2015-12-01
申请号：US12644863
申请日：2009-12-22
申请人： Masayoshi Seike , Yoshihiko Tashima
发明人： Masayoshi Seike , Yoshihiko Tashima
IPC分类号： G01N33/48 , G01N33/50 , G01N31/00 , G06F19/00 , G06F19/20 , G06F19/12 , G06F19/24
CPC分类号： G06F19/3437 , G06F19/00 , G06F19/12 , G06F19/20 , G06F19/24 , G16H50/50
摘要： The present invention is to present a diagnostic support apparatus for diabetes including a diagnostic support information generating unit which generates diagnostic support information of a patient based on a biological model for reproducing a pseudo-response which simulates a result of a glucose tolerance test for the patient. The biological model comprises a plurality of simulated organ blocks which are configured in such manner that inflow and outflow of glucose and/or inflow and outflow of insulin are reciprocally produced between each of the simulated organ blocks. The plurality of the simulated organ blocks respectively calculate at least one of a cumulative quantity and a concentration of glucose and/or at least one of a cumulative quantity and a concentration of insulin in the respective simulated organ blocks, based on a quantity of inflow and outflow of glucose and/or a quantity of inflow and outflow of insulin in the respective simulated organ blocks.
摘要翻译：本发明是提供一种用于糖尿病的诊断支持装置，其包括诊断支持信息生成单元，其基于用于再现模拟患者的葡萄糖耐量试验结果的伪响应的生物模型生成患者的诊断支持信息。生物模型包括多个模拟器官块，其被配置成使得葡萄糖的流入和流出和/或胰岛素的流入和流出在每个模拟器官区块之间相互产生。多个模拟器官块分别基于流入量分别计算各个模拟器官块中的葡萄糖的累积量和浓度和/或胰岛素的累积量和浓度中的至少一个，葡萄糖的流出和/或胰岛素在各个模拟器官块中的流入和流出量。

2. 发明申请

US20130130242A1 METHOD FOR DETERMINING PRESENCE OR ABSENCE OF CANCER CELL IN BIOLOGICAL SAMPLE, AND MOLECULAR MARKER AND KIT FOR DETERMINATION 审中-公开
标题翻译：用于确定生物样品中癌细胞存在或不存在的方法，以及用于确定的分子标记和试剂盒
公开(公告)号：US20130130242A1
公开(公告)日：2013-05-23
申请号：US13594526
申请日：2012-08-24
申请人： Ayako SAKAI , Yoshihiko TASHIMA , Masahiro KAJITA
发明人： Ayako SAKAI , Yoshihiko TASHIMA , Masahiro KAJITA
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/154 , C12Q2600/156
摘要： The present invention relates to a method for determining presence or absence of a cancer cell in a biological sample based on the analysis result obtained by analyzing methylation status of DNA extracted from the biological sample with a novel molecular marker allowing a determination of presence or absence of the cancer cell.
摘要翻译：本发明涉及一种基于通过分析从生物样品提取的DNA的甲基化状态获得的分析结果来确定生物样品中癌细胞存在或不存在的方法，其具有允许测定存在或不存在癌细胞。

3. 发明申请

US20100161299A1 DIAGNOSTIC SUPPORT APPARATUS FOR DIABETES AND COMPUTER PROGRAM PRODUCT 有权
标题翻译：糖尿病和计算机程序产品的诊断支持设备
公开(公告)号：US20100161299A1
公开(公告)日：2010-06-24
申请号：US12644863
申请日：2009-12-22
申请人： Masayoshi SEIKE , Yoshihiko Tashima
发明人： Masayoshi SEIKE , Yoshihiko Tashima
IPC分类号： G06G7/60 , G06G7/58 , G06G7/57
CPC分类号： G06F19/3437 , G06F19/00 , G06F19/12 , G06F19/20 , G06F19/24 , G16H50/50
摘要： The present invention is to present a diagnostic support apparatus for diabetes including a diagnostic support information generating unit which generates diagnostic support information of a patient based on a biological model for reproducing a pseudo-response which simulates a result of a glucose tolerance test for the patient. The biological model comprises a plurality of simulated organ blocks which are configured in such manner that inflow and outflow of glucose and/or inflow and outflow of insulin are reciprocally produced between each of the simulated organ blocks. The plurality of the simulated organ blocks respectively calculate at least one of a cumulative quantity and a concentration of glucose and/or at least one of a cumulative quantity and a concentration of insulin in the respective simulated organ blocks, based on a quantity of inflow and outflow of glucose and/or a quantity of inflow and outflow of insulin in the respective simulated organ blocks.
摘要翻译：本发明是提供一种用于糖尿病的诊断支持装置，其包括诊断支持信息生成单元，其基于用于再现模拟患者的葡萄糖耐量试验结果的伪响应的生物模型生成患者的诊断支持信息。生物模型包括多个模拟器官块，其被配置成使得葡萄糖的流入和流出和/或胰岛素的流入和流出在每个模拟器官区块之间相互产生。多个模拟器官块分别基于流入量分别计算各个模拟器官块中的葡萄糖的累积量和浓度和/或胰岛素的累积量和浓度中的至少一个，葡萄糖的流出和/或胰岛素在各个模拟器官块中的流入和流出量。

4. 发明申请

US20120190024A1 METHOD FOR DETERMINING PRESENCE OR ABSENCE OF EPITHELIAL CANCER-ORIGIN CELL IN BIOLOGICAL SAMPLE, AND MOLECULAR MARKER AND KIT THEREFOR 审中-公开
标题翻译：用于确定生物样品中上位癌细胞存在或不存在的方法及其分子标记和试剂盒
公开(公告)号：US20120190024A1
公开(公告)日：2012-07-26
申请号：US13381620
申请日：2010-06-30
申请人： Kaya Tai , Masahiro Kajita , Yoshihiko Tashima , Ayako Sakai
发明人： Kaya Tai , Masahiro Kajita , Yoshihiko Tashima , Ayako Sakai
IPC分类号： C12Q1/68 , C07H21/04
CPC分类号： C12Q1/6886 , C12Q2600/154
摘要： The present invention provides a method for determination of presence or absence of an epithelial cancer-derived cell in a biological sample obtained from a subject comprising the steps of: extracting DNA from the biological sample, analyzing methylation status of a CpG site located in at least one region represented by base sequences SEQ ID NOs: 1, 2, 3 and 4 in the DNA obtained from the step of extracting, and determining presence or absence of the epithelial cancer-derived cell in the biological sample based on an analysis result obtained from the step of analyzing.
摘要翻译：本发明提供一种用于确定从受试者获得的生物样品中存在或不存在上皮癌衍生细胞的方法，包括以下步骤：从生物样品中提取DNA，分析至少位于至少一个CpG位点的甲基化状态由从提取步骤获得的DNA中的碱基序列SEQ ID NO：1,2,3和4表示的一个区域，并且基于从生物样品中获得的分析结果确定生物样品中上皮癌来源的细胞的存在或不存在分析的步骤。

5. 发明申请

US20100331207A1 METHODS OF DETECTING NUCLEIC ACID WITH MICROARRAY AND PROGRAM PRODUCT FOR USE IN MICROARRAY DATA ANALYSIS 审中-公开
标题翻译：用微量元素检测核酸的方法和程序产品用于微量数据分析
公开(公告)号：US20100331207A1
公开(公告)日：2010-12-30
申请号：US12826029
申请日：2010-06-29
申请人： AYAKO SAKAI , YOSHIHIKO TASHIMA , MASAHIRO KAJITA
发明人： AYAKO SAKAI , YOSHIHIKO TASHIMA , MASAHIRO KAJITA
IPC分类号： C40B30/04 , C40B60/12
CPC分类号： C12Q1/6837 , G16B20/00 , G16B25/00
摘要： The invention provides a method of detecting, with a microarray, a target nucleic acid containing a base sequence to which a nucleic acid-binding protein binds, obtaining a signal from a correction probe not containing any sequence complementary to the base sequence to which the nucleic acid-binding protein binds for being used as a background to correct a signal obtained from a detection probe hybridizing to the target nucleic acid, as well as a computer program product for enabling a computer to detect, with a microarray, a target nucleic acid containing a base sequence to which a nucleic acid-binding protein binds.
摘要翻译：本发明提供了一种利用微阵列检测含有核酸结合蛋白结合的碱基序列的靶核酸的方法，从不含有与核酸的碱基序列互补的任何序列的校正探针获得信号，酸结合蛋白结合以用作背景以校正从与靶核酸杂交的检测探针获得的信号，以及用于使计算机能够用微阵列检测含有靶核酸的靶核酸的计算机程序产品核酸结合蛋白结合的碱基序列。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式