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1. 发明授权

US5039213A Optical equipment with a semitransparent mirror 失效
标题翻译：具有半透明镜的光学设备
公开(公告)号：US5039213A
公开(公告)日：1991-08-13
申请号：US416608
申请日：1989-10-03
申请人： Kenji Yamada , Yoichi Iki
发明人： Kenji Yamada , Yoichi Iki
IPC分类号： G02B5/08 , G02B27/10
CPC分类号： G02B27/144
摘要： In an optical system a semitransparent mirror which is disposed at a predetermined angle with respect to an optical axis and which has a semitransparent surface (for instance, a front surface) and a transparent surface (for instance, a rear surface) is so designed as to split a diverging or converging light incident thereon into a first optical path of light flux reflected from the semitransparent surface and a second light path of light flux transmitted through both the semitransparent and transparent surfaces. Furthermore, in order that the position of an image focused by the light flux reflected from the transparent surface coincides with the position of an image focused by the light flux reflected from the semitransparent surface, the transparent surface is made non-parallel with the semitransparent surface of the semitransparent mirror. The thickness of the mirror decreases or increases toward image planes depending upon whether converging light flux or diverging light flux is incident on the mirror.
摘要翻译：在光学系统中，相对于光轴以预定角度设置并且具有半透明表面（例如，前表面）和透明表面（例如，后表面）的半透明镜被设计为将入射到其上的发散光或会聚光分成由半透明表面反射的光束的第一光路和透过透明半透明表面的光束的第二光路。此外，为了使由透明面反射的光束聚焦的图像的位置与由半透明面反射的光束聚焦的图像的位置一致，透明面与半透明面不平行的半透明镜。根据会聚光束或发散光束是否入射到反射镜上，反射镜的厚度朝着图像平面减小或增加。

2. 发明申请

US20090042238A1 Method of evaluating cell function, system for evaluating cell function, fluorescent microscope system, phototherapy method and phototherapy system 审中-公开
标题翻译：细胞功能评估方法，细胞功能评估系统，荧光显微镜系统，光疗法和光疗法
公开(公告)号：US20090042238A1
公开(公告)日：2009-02-12
申请号：US12230672
申请日：2008-09-03
申请人： Takashi Sakurai , Yoichi Iki
发明人： Takashi Sakurai , Yoichi Iki
IPC分类号： C12Q1/02 , C12M1/34 , C12N13/00 , C12M1/36
CPC分类号： G01N21/6428 , A61B5/0064 , A61B5/0071 , A61N5/062 , G01N1/30 , G01N15/1475 , G01N21/6408 , G01N21/6458 , G01N33/5008 , G01N2015/1488
摘要： A proposition is to accurately evaluate a phototoxic property (cell function) concerning a living cell. To this end, an evaluating method of cell function includes the operations of dyeing a specific site of the living cell with a fluorescent dye, irradiating the living cell with light to measure changes in brightness of resulting fluorescence generated at an adjacent site of the specific site, and evaluating the phototoxic property based on the brightness changes. In the event of functional depression in the specific site, the fluorescent dye cannot be retained therein and is extravasated into the adjacent site through the membrane of the specific site. The present embodiment can measure the extent of this extravasation, making it possible to accurately evaluate the phototoxic property.
摘要翻译：一个命题是准确评估有关活细胞的光毒性（细胞功能）。为此，细胞功能的评估方法包括用荧光染料染色活细胞的特定部位的操作，用光照射活细胞以测量在特定部位的相邻部位产生的产生的荧光的亮度变化，并根据亮度变化评价光毒性。在特定部位发生功能性抑制的情况下，荧光染料不能保留在其中，并通过特定部位的膜外渗到相邻部位。本实施例可以测量这种外渗的程度，使得可以准确地评估光毒性。

3. 发明授权

US5691800A Ophthalmologic apparatus 失效
标题翻译：眼科仪器
公开(公告)号：US5691800A
公开(公告)日：1997-11-25
申请号：US580991
申请日：1996-01-03
申请人： Yoichi Iki , Seiho Yamashita
发明人： Yoichi Iki , Seiho Yamashita
IPC分类号： A61B3/10 , A61B3/103
CPC分类号： A61B3/103
摘要： An ophthalmologic apparatus comprises a measuring device for measuring an eye being examined, a display for displaying the result of the measurement by the measuring device, a counter for counting the number of times of measurement of the eye being examined with respect to each of the right and left eyes, and a display control device for causing the display to display the number of times of measurement of each of the right and left eyes counted by the counter.
摘要翻译：眼科装置包括用于测量被检眼睛的测量装置，用于显示测量装置的测量结果的显示器，用于计数正在被检查的眼睛的测量次数相对于每个右侧的计数器的计数器和左眼，以及显示控制装置，用于使显示器显示由计数器计数的每个右眼和左眼的测量次数。

4. 发明授权

US5548355A Ophthalmologic apparatus detecting position of bright points on an eye to be examined 失效
标题翻译：检测眼睛上亮点的位置的眼科装置
公开(公告)号：US5548355A
公开(公告)日：1996-08-20
申请号：US144248
申请日：1993-11-01
申请人： Yoichi Iki
发明人： Yoichi Iki
IPC分类号： A61B3/10 , A61B3/107 , G06T7/60
CPC分类号： G06T7/604 , A61B3/107
摘要： The apparatus radiates light onto an eye to be examined and picks up an image of the eye, which is irradiated with light. And then the apparatus compares image information obtained from the image pickup with a threshold determined in advance for the image information so as to store the image information larger than the threshold. The apparatus calculates a measured value of the eye to be examined on the basis of the stored image information.
摘要翻译：该装置将光照射到要检查的眼睛上，并拾取用光照射的眼睛的图像。然后，该装置将从图像拾取获得的图像信息与对于图像信息预先确定的阈值进行比较，以便存储大于阈值的图像信息。该装置基于存储的图像信息计算要检查的眼睛的测量值。

5. 发明授权

US08094914B2 Microscope system and image processing method used for observation of a specimen 有权
标题翻译：用于观察样本的显微镜系统和图像处理方法
公开(公告)号：US08094914B2
公开(公告)日：2012-01-10
申请号：US11661235
申请日：2005-09-15
申请人： Yoichi Iki , Yutaka Sasaki , Mikes Josef , Svoboda Miroslav , Sedlak Roman
发明人： Yoichi Iki , Yutaka Sasaki , Mikes Josef , Svoboda Miroslav , Sedlak Roman
IPC分类号： G06K9/00 , G06K9/32
CPC分类号： G02B21/367
摘要： An object of the present invention is to provide a microscope system and an image processing method which are practical and capable of imaging a specimen efficiently in a short period of time and also ensuring reduction of the data amount of a generated image. Accordingly, the microscope system includes a storage section 24, 27 which stores identification information of a specimen 10A, a macro image and a micro image in a correlated manner, a stage member 11 on which the specimen as an observation target is mounted, an acquiring section 39B, 40 which acquires identification information of the specimen, a first display section 16, 22, 40, 47, 24 which displays a macro image of the specimen by reading a macro image correlated with the identification information from the storage section (or by imaging the specimen), a second display section 12 to 22, 47, 40, 24 which displays a micro image of the specimen by imaging the specimen, and an additional storing section 40 which additionally stores in the storage section in accordance with instruction from outside a micro image displayed on the second display section in a correlated manner with the macro image displayed on the first display section and the identification information acquired by the acquiring section.
摘要翻译：本发明的目的是提供一种实用且能够在短时间内有效地对样本进行成像并且还确保减少生成的图像的数据量的显微镜系统和图像处理方法。因此，显微镜系统具有以相关方式存储检体10A，宏观图像和微图像的识别信息的存储部24,27，安装作为观察对象的检体的台部件11，通过从存储部读取与识别信息相关的宏图像，或者从存储部分读取与标识信息相关的宏图像，或者从存储部分读取与该识别信息相关的宏图像的第一显示部分16,22,40,47,24，显示样本的宏观图像的部分39B，40，成像试样），第二显示部分12至22,47,40,24，其通过使样本成像来显示样本的微观图像;以及附加存储部分40，其根据来自外部的指令另外存储在存储部分中以与第一显示部显示的宏观图像相关联的方式显示在第二显示部上的微图像和由ac获取的识别信息令人兴奋的部分。

6. 发明授权

US5883693A Ophthalmic refractor 失效
$Ophthalmic refractor$
标题翻译：眼科折射仪
公开(公告)号：US5883693A
公开(公告)日：1999-03-16
申请号：US967031
申请日：1997-11-10
申请人： Yoichi Iki
发明人： Yoichi Iki
IPC分类号： A61B3/02 , A61B3/028 , A61B3/032
CPC分类号： A61B3/032 , A61B3/028
摘要： An ophthalmic refractor is constructed to judge whether a visual acuity value of a symbol with a mask is minimum or maximum among values in a selected charts, select a chart containing a symbol indicating a visual acuity value smaller than the minimum visual acuity value when the visual acuity value is judged to be minimum, and select a chart containing a symbol indicating a visual acuity value larger than the maximum visual acuity value when the visual acuity value is judged to be maximum.
摘要翻译：构造眼科折射器以判断在所选择的图表中的值之间具有掩模的符号的视敏度值是最小还是最大值，当视觉上选择包含指示视力值的符号的图表时，选择视力值小于最小视力值视觉度值被判断为最小，并且当视力值被判断为最大时，选择包含指示视力值大于最大视力值的符号的图表。

7. 发明申请

US20080095424A1 Microscope System And Image Processing Method 有权
标题翻译：显微镜系统和图像处理方法
公开(公告)号：US20080095424A1
公开(公告)日：2008-04-24
申请号：US11661235
申请日：2005-09-15
申请人： Yoichi Iki , Yutaka Sasaki , Mikes Josef , Svoboda Miroslav , Sedlak Roman
发明人： Yoichi Iki , Yutaka Sasaki , Mikes Josef , Svoboda Miroslav , Sedlak Roman
IPC分类号： G06K9/00
CPC分类号： G02B21/367
摘要： An object of the present invention is to provide a microscope system and an image processing method which are practical and capable of imaging a specimen efficiently in a short period of time and also ensuring reduction of the data amount of a generated image. Accordingly, the microscope system includes a storage section 24, 27 which stores identification information of a specimen 10A, a macro image and a micro image in a correlated manner, a stage member 11 on which the specimen as an observation target is mounted, an acquiring section 39B, 40 which acquires identification information of the specimen, a first display section 16, 22, 40, 47, 24 which displays a macro image of the specimen by reading a macro image correlated with the identification information from the storage section (or by imaging the specimen), a second display section 12 to 22, 47, 40, 24 which displays a micro image of the specimen by imaging the specimen, and an additional storing section 40 which additionally stores in the storage section in accordance with instruction from outside a micro image displayed on the second display section in a correlated manner with the macro image displayed on the first display section and the identification information acquired by the acquiring section.
摘要翻译：本发明的目的是提供一种实用且能够在短时间内有效地对样本进行成像并且还确保减少生成的图像的数据量的显微镜系统和图像处理方法。因此，显微镜系统具备存储部件24,27，该存储部件24,27以相关的方式存储试样10A的识别信息，宏观图像和微观图像，安装作为观察对象的试样的载物台11，获取部件39B，40，其获取样本的识别信息;第一显示部分16,22,40,47,24，其通过从存储部分读取与识别信息相关的宏图像来显示样本的宏观图像或通过对样本进行成像），通过使样本成像来显示样本的微观图像的第二显示部分12至22,47,40,24以及根据指令另外存储在存储部分中的附加存储部分40 从显示在第二显示部分上的微图像与第一显示部分上显示的宏图像相关联的微图像和由第一显示部分获取的识别信息获取部分。

8. 发明授权

US5815240A Ophthalmologic device having means for classifying the picture data in the frame memory into the bright point regions and the mask regions 失效
标题翻译：具有用于将帧存储器中的图像数据分类为亮点区域和掩模区域的装置的眼科装置
公开(公告)号：US5815240A
公开(公告)日：1998-09-29
申请号：US838778
申请日：1997-04-10
申请人： Yoichi Iki
发明人： Yoichi Iki
IPC分类号： A61B3/10 , A61B3/103 , A61B3/107
CPC分类号： A61B3/107 , A61B3/103
摘要： An ophthalmologic device measures corneal curvature and ocular refractive power of the eye by imaging the positions of a plurality of bright points which result from plural light rays and by imaging a predetermined pattern of the eye. The ophthalmologic device includes a frame memory to store picture data of the eye which has been imaged by a video camera. The picture data in memory is classified into bright spot regions in which bright spots are present one at a time, a corneal reflected image region in which a reflected image from the cornea of a predetermined pattern is projected into the fundus of the eye, and mask regions in which the bright points and the corneal reflected image are not present. The picture data having a luminosity greater than a predetermined threshold value is stored for later calculation of a centroid of the bright points to measure the corneal curvature of the eye.
摘要翻译：眼科装置通过对由多个光线产生的多个亮点的位置进行成像并通过对眼睛的预定图案进行成像来测量眼睛的角膜曲率和眼屈光力。眼科装置包括用于存储由摄像机成像的眼睛的图像数据的帧存储器。存储器中的图像数据被分类为其中一次一个地存在亮点的亮点区域，其中来自预定图案的角膜的反射图像投射到眼睛的眼底中的角膜反射图像区域，以及掩模亮点和角膜反射图像不存在的区域。存储具有大于预定阈值的亮度的图像数据以用于稍后计算亮点的质心以测量眼睛的角膜曲率。

9. 发明授权

US5737058A Eye examination apparatus using ultrasonic wave radiation 失效
标题翻译：眼科检查仪器采用超声波辐射
公开(公告)号：US5737058A
公开(公告)日：1998-04-07
申请号：US589632
申请日：1996-01-22
申请人： Izumi Umemura , Nobuyuki Miyake , Seiho Yamashita , Yoichi Iki
发明人： Izumi Umemura , Nobuyuki Miyake , Seiho Yamashita , Yoichi Iki
IPC分类号： A61B3/10 , A61B8/10 , G01S15/88 , G01S15/89 , A61B3/14
CPC分类号： G01S15/899 , A61B8/10 , G01S15/88
摘要： An eye examination apparatus comprises an ultrasonic transmitter for transmitting ultrasonic wave radiation to an area around an eye to be examined, an ultrasonic receiver for receiving the reflected wave radiation of the ultrasonic wave radiation, and a judging device for judging whether the eye to be examined is the right eye or the left eye based on the result of the reception by the ultrasonic receiver.
摘要翻译：眼睛检查装置包括：超声波发射器，用于将超声波辐射发射到待检眼睛周围的区域;超声波接收器，用于接收超声波辐射的反射波辐射;以及判断装置，用于判断被检眼是基于超声波接收器的接收结果的右眼或左眼。

10. 发明授权

US5555039A Eye measuring apparatus having an automatic fogging producing mechanism and method thereof 失效
标题翻译：具有自动起雾生成机构的眼测量装置及其方法
公开(公告)号：US5555039A
公开(公告)日：1996-09-10
申请号：US518021
申请日：1995-08-22
申请人： Yoichi Iki , Nobuyki Miyake , Yasunori Ueno
发明人： Yoichi Iki , Nobuyki Miyake , Yasunori Ueno
IPC分类号： A61B3/103 , A61B3/10 , A61B3/00
CPC分类号： A61B3/103
摘要： An eye measuring apparatus includes a refracting power detector for measuring the refracting power of an eye to be examined, a fogging producer for moving the position of a target image in the direction of the optical axis of the eye to be examined, and a feedback controller for receiving an output from the refracting power detector, and moving the position of the target image in a direction, in which accommodation of the eye to be examined is relaxed, in accordance with refracting power information measured in a predetermined meridian direction of the eye to be examined and astigmatic information of the eye to be examined obtained from refracting power values measured in a plurality of meridian directions of the eye to be examined.
摘要翻译：眼睛测量装置包括：用于测量待检眼睛的折射力的折射力检测器，用于使被检眼的光轴方向移动目标图像的位置的雾化生成器;以及反射控制器用于接收来自折射功率检测器的输出，并且根据在眼睛的预定子午线方向上测量的折射功率信息，沿着要被检查的眼睛的容纳松弛的方向移动目标图像的位置，从被检眼的多个子午线方向测定的折射功率值得到待检查的眼睛的像散信息。

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