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1. 发明授权

US08715761B2 Flavor molecules 有权
标题翻译：风味分子
公开(公告)号：US08715761B2
公开(公告)日：2014-05-06
申请号：US12795201
申请日：2010-06-07
申请人： Andrew Daniher , Yili Wang
发明人： Andrew Daniher , Yili Wang
IPC分类号： A23L1/236 , A23L1/229 , C07D213/59 , C07D213/80 , C07D401/04 , C07D213/38 , C07D213/64 , C07D213/67 , C07D277/30 , C07D277/24
CPC分类号： C07D307/46 , A23L27/2052 , A23L27/2054 , A23L27/2056 , A23L27/30 , C07D213/50 , C07D213/61 , C07D213/64 , C07D213/74 , C07D261/08 , C07D265/06 , C07D277/24 , C07D405/12
摘要： A method of providing a range of flavors to an orally-receivable or ingestible product, the method including adding at least one compound, including salts thereof, of the formula: wherein R1 may be H, OH, O(CH2)2OH, OCH2OCH3 or R2 may be selected from a range of 5- and 6-membered heterocyclic rings, and wherein R3 may be H or OH. The compounds give rise to a wide range of flavors, and some are useful as sweetness enhancers, this allowing sweetener content to be reduced while maintaining sweetness. Also disclosed are orally-receivable or ingestible products including the compounds.
摘要翻译：一种向口服可接受或可摄入产品提供一系列风味的方法，所述方法包括加入下式的至少一种化合物，包括其盐：其中R 1可以是H，OH，O（CH 2）2 OH，OCH 2 OCH 3或 R 2可以选自5-和6-元杂环的一个范围，并且其中R 3可以是H或OH。这些化合物产生广泛的口味，有些可用作甜味增强剂，这使得甜味剂含量在保持甜度的同时减少。还公开了包括这些化合物的口服可接受或可摄入的产品。

2. 发明申请

US20100040753A1 FLAVOR MOLECULES 有权
标题翻译：风味分子
公开(公告)号：US20100040753A1
公开(公告)日：2010-02-18
申请号：US12389900
申请日：2009-02-20
申请人： Andrew Daniher , Yili Wang
发明人： Andrew Daniher , Yili Wang
IPC分类号： A23L1/226 , C07D213/64 , C07D277/24 , C07D401/04 , C07D413/04
CPC分类号： C07D307/46 , A23L27/2052 , A23L27/2054 , A23L27/2056 , A23L27/30 , C07D213/50 , C07D213/61 , C07D213/64 , C07D213/74 , C07D261/08 , C07D277/10 , C07D405/12
摘要： A method of providing a range of flavors to an orally-receivable or ingestible product, the method including adding at least one compound, including salts thereof, of the formula: wherein R1 may be H, OH, O(CH2)2OH, OCH2OCH3 or R2 may be selected from a range of 5- and 6-membered heterocyclic rings, and wherein R3 may be H or OH. The compounds give rise to a wide range of flavors, and some are useful as sweetness enhancers, this allowing sweetener content to be reduced while maintaining sweetness. Also disclosed are orally-receivable or ingestible products including the compounds.
摘要翻译：一种向口服可接受或可摄入产品提供一系列风味的方法，所述方法包括加入下式的至少一种化合物，包括其盐：其中R 1可以是H，OH，O（CH 2）2 OH，OCH 2 OCH 3或 R 2可以选自5-和6-元杂环的一个范围，并且其中R 3可以是H或OH。这些化合物产生广泛的口味，有些可用作甜味增强剂，这使得甜味剂含量在保持甜度的同时减少。还公开了包括这些化合物的口服可接受或可摄入的产品。

3. 发明授权

US07001899B2 Interleukin converting enzyme inhibitors 失效
标题翻译：白介素转化酶抑制剂
公开(公告)号：US07001899B2
公开(公告)日：2006-02-21
申请号：US10457720
申请日：2003-06-09
申请人： John August Wos , Yili Wang , Kofi Abeka Oppong , Steven Victor O'Neil , Michael Christopher Laufersweiler , David Lindsey Soper , Biswanath De , Thomas Prosser Demuth, Jr.
发明人： John August Wos , Yili Wang , Kofi Abeka Oppong , Steven Victor O'Neil , Michael Christopher Laufersweiler , David Lindsey Soper , Biswanath De , Thomas Prosser Demuth, Jr.
IPC分类号： C07D405/12 , C07D405/14 , C07D417/12 , C07D417/14 , A61K31/554
CPC分类号： C07D405/12 , A61K38/00 , C07D405/14 , C07D409/14 , C07D417/12 , C07D417/14 , C07K5/0202 , C07K5/06078
摘要： The present invention relates to novel compounds, compositions comprising said compounds, and uses thereof, said compounds having the formula: wherein each X is independently selected from: i) —C(W)2—; ii) —C(O)—; iii) —NR2—; iv) —S—; v) —S(O)—; vi) —S(O)2—; vii) two units, one from each adjacent X unit, can be taken together to form a substituted or unsubstituted double bond having the formula —CW═CW—; wherein each W is hydrogen of a unit having the formula —(L2)j—R2, the index j is 0 or 1; R is a carbocyclic or heterocyclic aryl ring; R1 is a cysteine trap; each R2 is independently a suitable substituent; and L, L1, and L2 are linking units.
摘要翻译：本发明涉及新化合物，包含所述化合物的组合物及其用途，所述化合物具有下式：化学式id =“CHEM-US-00001”num =“000

4. 发明申请

US20130302497A1 Taste Enhancement 审中-公开
标题翻译：口味增强
公开(公告)号：US20130302497A1
公开(公告)日：2013-11-14
申请号：US13822023
申请日：2011-09-13
申请人： Tarun Bhowmik , Yili Wang , Pablo Victor Krawec
发明人： Tarun Bhowmik , Yili Wang , Pablo Victor Krawec
IPC分类号： A23L1/22
CPC分类号： A23L27/88 , A23L27/202 , A23L27/30
摘要： A method of enhancing a taste sensation in a consumable composition, comprising the addition thereto of a taste provider selected from a taste provider compound and a mixture of a taste provider compound with a taste enhancement compound, there being additionally added thereto a taste sensation-enhancing quantity of choline chloride.
摘要翻译：一种增加消耗性组合物中的味觉感觉的方法，包括向味道提供者添加选自味道提供者化合物和味道提供者化合物与味觉增强化合物的混合物的添加剂，另外添加了味觉增强剂氯化胆碱的量。

5. 发明申请

US20110029923A1 INTEGRATING TRANSPORT MODES INTO A COMMUNICATION STREAM 有权
标题翻译：将传输模式集成到通信流中
公开(公告)号：US20110029923A1
公开(公告)日：2011-02-03
申请号：US12512700
申请日：2009-07-30
申请人： Jon Changzheng Xu , Christer Garbis , Stephanie Teng , Yili Wang , Karl Petter Karlsson
发明人： Jon Changzheng Xu , Christer Garbis , Stephanie Teng , Yili Wang , Karl Petter Karlsson
IPC分类号： G06F15/16 , G06F3/048
CPC分类号： H04L51/36 , G06Q10/10 , H04L12/40013
摘要： Integrating multiple transport modes into a single communication stream on a computing device such as a mobile computing device. One or more recipients and one or more transport modes available for communication with the one or more recipients are provided to a user. An application program executing on the computing device receives a first message from the user to send to one or more selected recipients. The computing device transmits the received first message to the selected recipients via a first transport mode. Thereafter, the computing device receives a second message from one of the recipients via a second transport mode. The received second message is displayed to the user in the same communication stream by the application program. As an example, the user uses the application program to communicate with the recipients using text messaging, electronic mail message, and other transport modes.
摘要翻译：将多个传输模式集成到诸如移动计算设备的计算设备上的单个通信流中。一个或多个接收者和一个或多个可用于与一个或多个接收者进行通信的传输模式被提供给用户。在计算设备上执行的应用程序从用户接收第一消息以发送给一个或多个选择的接收者。计算设备经由第一传输模式将接收到的第一消息发送到所选择的接收者。此后，计算设备经由第二传输模式从一个接收者接收第二消息。所接收的第二消息由应用程序以相同的通信流显示给用户。作为示例，用户使用应用程序使用文本消息，电子邮件消息和其他传输模式与接收者通信。

6. 发明申请

US20090186138A1 Method of Flavoring 审中-公开
标题翻译：调味方法
公开(公告)号：US20090186138A1
公开(公告)日：2009-07-23
申请号：US12357724
申请日：2009-01-22
申请人： Xiaogen YANG , Yili WANG , Robert G. EILERMAN , Jason JORDAN
发明人： Xiaogen YANG , Yili WANG , Robert G. EILERMAN , Jason JORDAN
IPC分类号： A23L1/22 , C07C69/67 , C07D307/20 , C07D309/32
CPC分类号： A23L27/204 , A23L27/205 , C07C69/017 , C07C69/24 , C07C69/533 , C07D309/40
摘要： A method of providing a desirable vanilla beany flavor in an orally-receivable product, includes adding to a product base at least one of divanillyl succinate or at least one compound according to Formula I or Formula II in which R′ is selected from the group consisting of hydrogen, methyl and —CHO, and R is selected from the group consisting of hydrogen. C1-C10 linear alkyl. C3-C10 branched alkyl, C2-C10 linear alkenyl, C3-C10 branched alkenyl, C1-C10 hydroxyalkyl, C2-C10 carboxyalkyl, and tetrahydrofuranyl.
摘要翻译：一种在口服可接收产品中提供所需香草香味的方法包括向产物基质中加入至少一种琥珀酸二苯基酯或至少一种式I或式II化合物，其中R'选自的氢，甲基和-CHO，R选自氢。 C1-C10直链烷基。 C 3 -C 10支链烷基，C 2 -C 10直链烯基，C 3 -C 10支链烯基，C 1 -C 10羟基烷基，C 2 -C 10羧基烷基和四氢呋喃基。

7. 发明授权

US6066751A Process for making epoxide intermediates 失效
标题翻译：制备环氧化物中间体的方法
公开(公告)号：US6066751A
公开(公告)日：2000-05-23
申请号：US148539
申请日：1998-09-04
申请人： John August Wos , Jack Snyder Amburgey, Jr. , Mitchell Anthony deLong , Yili Wang , Haiyan George Dai , Biswanath De
发明人： John August Wos , Jack Snyder Amburgey, Jr. , Mitchell Anthony deLong , Yili Wang , Haiyan George Dai , Biswanath De
IPC分类号： C07D301/14 , C07C405/00 , C07D303/12
CPC分类号： C07C405/00
摘要： It has been surprisingly discovered that the disadvantages of the lengthy literature procedures to synthesize 13,14-dihydro prostaglandin A, E, and F derivatives can be overcome using a novel Methyl 7-(2-hydroxy-5-(2-(2-oxiranyl)ethyl)-4-(1,1,2,2 tetramethyl-1-silapropoxy)cyclopentyl) heptanoate intermediate, which can be synthesized from commercially available Methyl 7-[3-(R)-hydroxy-5-oxo-1-cyclopent-1-yl] heptanoate. This novel intermediate can be coupled with oxygen, carbon, sulfur, and nitrogen nucleophiles, in the presence of a base or a Lewis acid, in a ring-opening process to provide 13,14-dihydro prostaglandin A, E, and F derivatives.
摘要翻译：已经令人惊讶地发现，使用新的7-（2-羟基-5-（2-（2-（2-甲氧基乙氧基）苯基）甲基丙烯酸甲酯，可以克服长时间合成13,14-二氢前列腺素A，E和F衍生物的文献程序的缺点，环氧乙烷基）乙基）-4-（1,1,2,2-四甲基-1-硅基丙氧基）环戊基）庚酸酯中间体，其可以从市售的7- [3-（R） - 羟基-5-氧代-1 环戊-1-基]庚酸乙酯。这种新型中间体可以在碱或路易斯酸的存在下与氧，碳，硫和氮亲核试剂在开环过程中偶联，得到13,14-二氢前列腺素A，E和F衍生物。

8. 发明授权

US11122826B2 Organic compounds 有权
公开(公告)号：US11122826B2
公开(公告)日：2021-09-21
申请号：US14916765
申请日：2013-10-02
申请人： GIVAUDAN S.A. , Yili Wang
发明人： Yili Wang
IPC分类号： A23L27/20 , A23L27/00 , C07C233/49 , A23L2/56 , A23L2/39 , A23L27/50
摘要： A compound according to the formula (I) or edible salts thereof, Wherein R together with the carbonyl group to which it is attached is a residue of a carboxylic acid. Said compounds may be used in edible compositions such as foods and beverages to impart or modify flavour and mouth feel to said compositions.

9. 发明授权

US10660355B2 Organic compounds 有权
公开(公告)号：US10660355B2
公开(公告)日：2020-05-26
申请号：US14916765
申请日：2013-10-02
申请人： GIVAUDAN S.A. , Yili Wang
发明人： Yili Wang
IPC分类号： A23L27/20 , A23L27/00 , C07C233/49 , A23L2/56 , A23L2/39 , A23L27/50
摘要： A compound according to the formula (I) or edible salts thereof, Wherein R together with the carbonyl group to which it is attached is a residue of a carboxylic acid. Said compounds may be used in edible compositions such as foods and beverages to impart or modify flavour and mouth feel to said compositions.

10. 发明授权

US07138395B2 Interleukin-1β converting enzyme inhibitors 失效
标题翻译：白细胞介素-1β转换酶抑制剂
公开(公告)号：US07138395B2
公开(公告)日：2006-11-21
申请号：US10457188
申请日：2003-06-09
申请人： Steven Victor O'Neil , Michael Christopher Laufersweiler , Yili Wang , Kofi Abeka Oppong , David Lindsey Soper , John August Wos , Biswanath De , Thomas Prosser Demuth, Jr.
发明人： Steven Victor O'Neil , Michael Christopher Laufersweiler , Yili Wang , Kofi Abeka Oppong , David Lindsey Soper , John August Wos , Biswanath De , Thomas Prosser Demuth, Jr.
IPC分类号： C07D471/04 , C07D498/04 , A61K31/4995 , A61K31/537 , A61P29/00
CPC分类号： C07D471/04 , C07D487/04
摘要： The present invention relates to novel compounds, compositions comprising said compounds, and uses thereof, said compounds having the formula: X is —CH2—, —O— or —NR9—; R is a carbocyclic or heterocyclic ring; R1 is a cysteine trap; R2a, R2a′, R2b, and R2b′ are each independently hydrogen, C1–C4 alkyl, C1–C4 alkoxy, and mixtures thereof; or R2a′ and R2b′ can taken together to form a double bond; R9 is hydrogen or a unit having the formula -L2-R10; L is the same as defined herein above; R10 is hydrogen; substituted or unsubstituted C1–C6 linear; branched, or cyclic hydrocarbyl; substituted or unsubstituted aryl; substituted or unsubstituted C1–C9 heterocyclic; and substituted or unsubstituted heteroaryl.
摘要翻译：本发明涉及新化合物，包含所述化合物的组合物及其用途，所述具有下式的化合物：X为-CH 2 - ， - O-或-NR 9 > - ; R是碳环或杂环; R 1是半胱氨酸阱; R 2a，R 2a，R 2b和R 2b'各自独立地为氢，C

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