专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20060122197A1 Amido compounds and their use as pharmaceuticals 审中-公开
公开(公告)号：US20060122197A1
公开(公告)日：2006-06-08
申请号：US11199763
申请日：2005-08-09
申请人： Wenqing Yao , Jincong Zhuo , Brian Metcalf , Ding-Quan Qian , Yanlong Li
发明人： Wenqing Yao , Jincong Zhuo , Brian Metcalf , Ding-Quan Qian , Yanlong Li
IPC分类号： A61K31/506 , A61K31/4545 , A61K31/454 , C07D417/02 , C07D403/02 , C07D401/02
CPC分类号： C07D451/06 , C07D211/56 , C07D211/96 , C07D401/04 , C07D401/10 , C07D401/12 , C07D401/14 , C07D409/12 , C07D413/10 , C07D413/12 , C07D417/04
摘要： The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-β hydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess.

2. 发明申请

US20050288317A1 Amido compounds and their use as pharmaceuticals 审中-公开
标题翻译：酰胺化合物及其作为药物的用途
公开(公告)号：US20050288317A1
公开(公告)日：2005-12-29
申请号：US11159863
申请日：2005-06-23
申请人： Wenqing Yao , Yanlong Li , Meizhong Xu , Jincong Zhuo , Colin Zhang , Brian Metcalf
发明人： Wenqing Yao , Yanlong Li , Meizhong Xu , Jincong Zhuo , Colin Zhang , Brian Metcalf
IPC分类号： A61K31/40 , A61K31/445 , A61K31/4709 , A61K31/4745 , C07D211/96 , C07D401/04 , C07D401/06 , C07D401/14 , C07D491/10
CPC分类号： C07D491/10 , C07D211/96 , C07D401/04 , C07D401/06 , C07D401/14
摘要： The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-β hydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess.
摘要翻译：本发明涉及1型11-β羟基类固醇脱氢酶抑制剂，盐皮质激素受体（MR）的拮抗剂及其药物组合物。本发明的化合物可用于治疗与1-β羟基类固醇脱氢酶1型和/或与醛固酮过量相关的疾病的表达或活性相关的各种疾病。

3. 发明授权

US5587081A Thermophilic aerobic waste treatment process 失效
标题翻译：嗜热好氧废水处理工艺
公开(公告)号：US5587081A
公开(公告)日：1996-12-24
申请号：US233276
申请日：1994-04-26
申请人： Kenneth L. Norcross , Yanlong Li
发明人： Kenneth L. Norcross , Yanlong Li
IPC分类号： C02F3/00 , C02F3/12 , C02F3/20 , C02F3/26 , C02F11/06
CPC分类号： C02F3/1284 , C02F3/006 , C02F3/12 , C02F3/20 , C02F3/26 , Y02W10/15
摘要： A system for thermophilic aerobic destruction of pathogenic organisms and organic matter within waste water treatment sludge includes a tank for maintaining the sludge and an air transfer apparatus for injecting air into the sludge near the bottom thereof so as to bubble up through the sludge and react exothermically with the thermophilic microorganisms therein so as to kill or destroy the mesophilic micro- organisms within the sludge. The thermophilic reaction is preferably controlled within a desired temperature range by control of the flow of fresh air versus recycled air being injected into the sludge. The fresh air to recycle air ratio can be controlled by several different mechanisms so as to produce the desired temperature range. The air is also utilized to mix the sludge within the tank. A pumping apparatus is also provided for transferring sludge into and out of the tank and for recirculating the sludge for purposes of auxiliary mixing. The pump can also be utilized in conjunction with an eductor for drawing fresh air into the sludge. A process controller is advantageously useable in conjunction with the various equipment to control the overall system.
摘要翻译：废水处理污泥中病原菌和有机物的嗜热好氧破坏系统包括用于维持污泥的罐和用于将空气注入靠近其底部的污泥中的空气传送装置，以便通过污泥起泡并且放热反应与其中的嗜热微生物一起杀死或破坏污泥内的嗜温微生物。优选通过控制新鲜空气的流动与注入污泥中的循环空气来控制嗜热反应在期望的温度范围内。新鲜空气循环空气比可以通过几种不同的机制来控制，以便产生所需的温度范围。空气还用于将罐内的污泥混合。还提供了一种泵送装置，用于将淤泥输送到罐中并将污泥再循环以用于辅助混合。泵还可以与喷射器一起使用，以将新鲜空气吸入污泥中。过程控制器有利地与各种设备结合使用以控制整个系统。

4. 发明授权

US5885448A Thermophilic aerobic waste treatment process 失效
标题翻译：嗜热好氧废水处理工艺
公开(公告)号：US5885448A
公开(公告)日：1999-03-23
申请号：US876559
申请日：1997-06-16
申请人： Kenneth L. Norcross , Yanlong Li
发明人： Kenneth L. Norcross , Yanlong Li
IPC分类号： C02F3/00 , C02F3/12 , C02F3/20 , C02F3/26
CPC分类号： C02F3/1284 , C02F3/006 , C02F3/12 , C02F3/20 , C02F3/26 , Y02W10/15
摘要： A system for thermophilic aerobic destruction of pathogenic organisms and organic matter within waste water treatment sludge includes a tank for maintaining the sludge and an air transfer apparatus for injecting air into the sludge near the bottom thereof so as to bubble up through the sludge and react exothermically with the thermophilic microorganisms therein so as to kill or destroy the mesophilic microorganisms within the sludge. The thermophilic reaction is preferably controlled within a desired temperature range by control of the flow of fresh air versus recycled air being injected into the sludge. The fresh air to recycle air ratio can be controlled by several different mechanisms so as to produce the desired temperature range. The air is also utilized to mix the sludge within the tank. A pumping apparatus is also provided for transferring sludge into and out of the tank and for recirculating the sludge for purposes of auxiliary mixing. The pump can also be utilized in conjunction with an eductor for drawing fresh air into the sludge. A process controller is advantageously useable in conjunction with the various equipment to control the overall system.
摘要翻译：废水处理污泥中病原菌和有机物的嗜热好氧破坏系统包括用于维持污泥的罐和用于将空气注入靠近其底部的污泥中的空气传送装置，以便通过污泥起泡并且放热反应与其中的嗜热微生物一起杀死或破坏污泥中的嗜温微生物。优选通过控制新鲜空气的流动与注入污泥中的循环空气来控制嗜热反应在期望的温度范围内。新鲜空气循环空气比可以通过几种不同的机制来控制，以便产生所需的温度范围。空气还用于将罐内的污泥混合。还提供了一种泵送装置，用于将淤泥输送到罐中并将污泥再循环以用于辅助混合。泵还可以与喷射器一起使用，以将新鲜空气吸入污泥中。过程控制器有利地与各种设备结合使用以控制整个系统。

5. 发明授权

US5599450A Anaerobic upflow batch reactor 失效
标题翻译：厌氧上流批量反应器
公开(公告)号：US5599450A
公开(公告)日：1997-02-04
申请号：US560740
申请日：1995-11-20
申请人： Yanlong Li , Kenneth L. Norcross
发明人： Yanlong Li , Kenneth L. Norcross
IPC分类号： C02F1/00 , C02F3/12 , C02F3/28 , C02F3/30
CPC分类号： C02F3/2846 , C02F1/006 , C02F3/1263 , C02F3/301 , Y02W10/15
摘要： A method for providing a uniform plug flow through an anaerobic wastewater treatment reactor includes distributing incoming wastewater generally evenly near the bottom of reactor and evenly collecting the wastewater near an upper level thereof so as to produce upward plug flow through the reactor during filling, recycle and decanting and minimize horizontal mixing. Such plug flow encourages growth of heavier biomass near the bottom of the reactor where substrate is greatest and discourages growth of light biomass near the top of the reactor where substrate is least. Wastewater is also preferably recycled from the top to the bottom of the reactor. Apparatus is provided to be used in conjunction with the method. The apparatus is also usable in conjunction with a subsequent aerobic sequencing batch reactor.
摘要翻译：通过厌氧废水处理反应器提供均匀的塞子流的方法包括将进入的废水大致均匀地分布在反应器底部附近，并均匀地收集其上部附近的废水，以便在填充，再循环期间产生向上的塞子流通过反应器倾析并尽量减少水平混合。这种塞子流动促进了靠近反应器底部的较重生物质的生长，其中底物最大，并且阻止在基底最少的反应器顶部附近的轻生物质的生长。废水也优选从反应器的顶部到底部再循环。提供了与该方法结合使用的装置。该装置还可与随后的需氧分批反应器结合使用。

6. 发明授权

US5656155A Thermophilic aerobic waste treatment system 失效
标题翻译：嗜热好氧废物处理系统
公开(公告)号：US5656155A
公开(公告)日：1997-08-12
申请号：US560160
申请日：1995-11-20
申请人： Kenneth L. Norcross , Yanlong Li
发明人： Kenneth L. Norcross , Yanlong Li
IPC分类号： C02F3/00 , C02F3/12 , C02F3/20 , C02F3/26
CPC分类号： C02F3/1284 , C02F3/006 , C02F3/12 , C02F3/20 , C02F3/26 , Y02W10/15
摘要： A system for thermophilic aerobic destruction of pathogenic organisms and organic matter within waste water treatment sludge includes a tank for maintaining the sludge and an air transfer apparatus for injecting air into the sludge near the bottom thereof so as to bubble up through the sludge and react exothermically with the thermophilic microorganisms therein so as to kill or destroy the mesophilic micro- organisms within the sludge. The thermophilic reaction is preferably controlled within a desired temperature range by control of the flow of fresh air versus recycled air being injected into the sludge. The fresh air to recycle air ratio can be controlled by several different mechanisms so as to produce the desired temperature range. The air is also utilized to mix the sludge within the tank. A pumping apparatus is also provided for transferring sludge into and out of the tank and for recirculating the sludge for purposes of auxiliary mixing. The pump can also be utilized in conjunction with an eductor for drawing fresh air into the sludge. A process controller is advantageously useable in conjunction with the various equipment to control the overall system.
摘要翻译：废水处理污泥中病原菌和有机物的嗜热好氧破坏系统包括用于维持污泥的罐和用于将空气注入靠近其底部的污泥中的空气传送装置，以便通过污泥起泡并且放热反应与其中的嗜热微生物一起杀死或破坏污泥内的嗜温微生物。优选通过控制新鲜空气的流动与注入污泥中的循环空气来控制嗜热反应在期望的温度范围内。新鲜空气循环空气比可以通过几种不同的机制来控制，以便产生所需的温度范围。空气还用于将罐内的污泥混合。还提供了一种泵送装置，用于将淤泥输送到罐中并将污泥再循环以用于辅助混合。泵还可以与喷射器一起使用，以将新鲜空气吸入污泥中。过程控制器有利地与各种设备结合使用以控制整个系统。

7. 发明授权

US08288417B2 N-substituted piperidines and their use as pharmaceuticals 有权
标题翻译： N-取代的哌啶及其作为药物的用途
公开(公告)号：US08288417B2
公开(公告)日：2012-10-16
申请号：US13279700
申请日：2011-10-24
申请人： Wenqing Yao , Meizhong Xu , Colin Zhang , Yanlong Li , Jincong Zhuo , Brian W. Metcalf
发明人： Wenqing Yao , Meizhong Xu , Colin Zhang , Yanlong Li , Jincong Zhuo , Brian W. Metcalf
IPC分类号： A61K31/4523 , C07D211/00
CPC分类号： C07D401/14 , C07D211/60 , C07D211/96 , C07D401/04 , C07D401/12 , C07D405/12 , C07D409/12 , C07D413/04
摘要： The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-β hydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess.
摘要翻译：本发明涉及11-和bgr的抑制剂。 1型羟基类固醇脱氢酶，盐皮质激素受体（MR）的拮抗剂及其药物组合物。本发明的化合物可用于治疗与11-和bgr的表达或活性相关的各种疾病; 羟基类固醇脱氢酶1型和/或与醛固酮过量相关的疾病。

8. 发明申请

US20120040964A1 N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS 有权
标题翻译： N-取代的哌嗪及其作为药物的用途
公开(公告)号：US20120040964A1
公开(公告)日：2012-02-16
申请号：US13279700
申请日：2011-10-24
申请人： Wenqing Yao , Meizhong Xu , Colin Zhang , Yanlong Li , Jincong Zhuo , Brian W. Metcalf
发明人： Wenqing Yao , Meizhong Xu , Colin Zhang , Yanlong Li , Jincong Zhuo , Brian W. Metcalf
IPC分类号： A61K31/445 , C07D401/12 , A61K31/4545 , C07D409/12 , A61K31/4535 , C07D405/12 , A61K31/4525 , A61K31/4709 , C07D403/04 , A61K31/497 , A61K31/506 , A61K31/501 , A61K31/55 , A61P3/04 , A61P3/10 , A61P3/08 , A61P5/48 , A61P9/12 , A61P3/06 , A61P25/28 , A61P25/24 , A61P27/06 , A61P9/00 , A61P19/10 , A61P29/00 , A61P13/12 , A61P9/04 , A61P9/10 , A61P7/02 , A61P3/00 , C07D211/60
CPC分类号： C07D401/14 , C07D211/60 , C07D211/96 , C07D401/04 , C07D401/12 , C07D405/12 , C07D409/12 , C07D413/04
摘要： The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-β hydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess.
摘要翻译：本发明涉及11-和bgr的抑制剂。 1型羟基类固醇脱氢酶，盐皮质激素受体（MR）的拮抗剂及其药物组合物。本发明的化合物可用于治疗与11-bgr的表达或活性相关的各种疾病; 羟基类固醇脱氢酶1型和/或与醛固酮过量相关的疾病。

9. 发明授权

US08071624B2 N-substituted piperidines and their use as pharmaceuticals 有权
标题翻译： N-取代的哌啶及其作为药物的用途
公开(公告)号：US08071624B2
公开(公告)日：2011-12-06
申请号：US11159448
申请日：2005-06-23
申请人： Wenqing Yao , Meizhong Xu , Colin Zhang , Yanlong Li , Jincong Zhuo , Brian W. Metcalf
发明人： Wenqing Yao , Meizhong Xu , Colin Zhang , Yanlong Li , Jincong Zhuo , Brian W. Metcalf
IPC分类号： A61K31/4523 , C07D211/00
CPC分类号： C07D401/14 , C07D211/60 , C07D211/96 , C07D401/04 , C07D401/12 , C07D405/12 , C07D409/12 , C07D413/04
摘要： The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-β hydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess.
摘要翻译：本发明涉及11-和bgr的抑制剂。 1型羟基类固醇脱氢酶，盐皮质激素受体（MR）的拮抗剂及其药物组合物。本发明的化合物可用于治疗与11-bgr的表达或活性相关的各种疾病; 羟基类固醇脱氢酶1型和/或与醛固酮过量相关的疾病。

10. 发明申请

US20060004049A1 N-substituted piperidines and their use as pharrmaceuticals 有权
标题翻译： N-取代的哌啶及其作为药物的用途
公开(公告)号：US20060004049A1
公开(公告)日：2006-01-05
申请号：US11159448
申请日：2005-06-23
申请人： Wenqing Yao , Meizhong Xu , Colin Zhang , Yanlong Li , Jincong Zhuo , Brian Metcalf
发明人： Wenqing Yao , Meizhong Xu , Colin Zhang , Yanlong Li , Jincong Zhuo , Brian Metcalf
IPC分类号： C07D211/30 , A61K31/445
CPC分类号： C07D401/14 , C07D211/60 , C07D211/96 , C07D401/04 , C07D401/12 , C07D405/12 , C07D409/12 , C07D413/04
摘要： The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-β hydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess.
摘要翻译：本发明涉及1型11-β羟基类固醇脱氢酶抑制剂，盐皮质激素受体（MR）的拮抗剂及其药物组合物。本发明的化合物可用于治疗与1-β羟基类固醇脱氢酶1型和/或与醛固酮过量相关的疾病的表达或活性相关的各种疾病。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式