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1. 发明授权

US08971986B2 Multi-modality medical image viewing 有权
标题翻译：多模态医学图像观看
公开(公告)号：US08971986B2
公开(公告)日：2015-03-03
申请号：US13593552
申请日：2012-08-24
申请人： Yang-Ming Zhu , Xiangyu Wu , Charles A. Nortmann , Ronald W. Sukalac , Steven M. Cochoff , L. Alan Love , Richard Cheng-Hsiu Chen , Chris A. Dauterman , Madhavi Ahuja , Dawn M. Maniawski
发明人： Yang-Ming Zhu , Xiangyu Wu , Charles A. Nortmann , Ronald W. Sukalac , Steven M. Cochoff , L. Alan Love , Richard Cheng-Hsiu Chen , Chris A. Dauterman , Madhavi Ahuja , Dawn M. Maniawski
IPC分类号： A61B5/05 , G06F19/00
CPC分类号： G16H30/20 , A61B5/05 , A61B6/463 , G06F17/30899 , G06F17/30905 , G06F19/00 , G06F19/321 , G06T2200/24 , G16H30/00 , G16H30/40 , G16H40/63
摘要： A medical imaging system (10) comprises one or more displays (66). A viewer device (86) generates an interactive user interface screen (80) on the display (66), which viewer device (86) enables a user to simultaneously inspect selected image data of multiple patients or multiple images.
摘要翻译：医疗成像系统（10）包括一个或多个显示器（66）。观看者设备（86）在显示器（66）上生成交互式用户界面屏幕（80），该观看者设备（86）使得用户能够同时检查多个患者或多个图像的所选图像数据。

2. 发明授权

US08749579B2 Pixel-feature hybrid fusion for PET/CT images 有权
标题翻译：用于PET / CT图像的像素特征混合融合
公开(公告)号：US08749579B2
公开(公告)日：2014-06-10
申请号：US13145135
申请日：2009-12-23
申请人： Yang-Ming Zhu , Charles A. Nortmann
发明人： Yang-Ming Zhu , Charles A. Nortmann
IPC分类号： G09G5/00
CPC分类号： G06T11/001 , A61B6/037 , G06T15/503
摘要： An image display method comprises: color coding a second image respective to an intensity spectrum with a portion or portions of the intensity spectrum set to be transparent to generate a color coded second image; combining a first image and the color coded second image to generate a fused image; and displaying the fused image. An image display system comprises: an image generating module configured to generate an image by color coding an input image in accordance with a colormap assigning colors to intensities of an intensity spectrum; a colormap modifying module configured to select a portion of the intensity spectrum to be transparent; and a display configured to display the generated image.
摘要翻译：一种图像显示方法包括：对强度谱进行颜色编码，其中所述强度谱的部分或部分设置为透明的，以产生颜色编码的第二图像; 组合第一图像和所述颜色编码的第二图像以生成融合图像; 并显示融合图像。一种图像显示系统，包括：图像生成模块，被配置为根据将颜色分配给强度谱强度的色彩图像，对输入图像进行彩色编码来生成图像; 配置为选择所述强度谱的一部分是透明的色彩变换模块; 以及被配置为显示所生成的图像的显示器。

3. 发明授权

US08553961B2 Automatic pre-alignment for registration of medical images 失效
标题翻译：自动预校准用于医学图像的注册
公开(公告)号：US08553961B2
公开(公告)日：2013-10-08
申请号：US13054109
申请日：2009-07-20
申请人： Yang-Ming Zhu , Steven M. Cochoff , Cheng-Hsiu Chen
发明人： Yang-Ming Zhu , Steven M. Cochoff , Cheng-Hsiu Chen
IPC分类号： G06K9/00 , G06K9/46
CPC分类号： G06T7/38 , G06T2200/04 , G06T2207/10081 , G06T2207/10104 , G06T2207/10136 , G06T2207/20076 , G06T2207/30196
摘要： In image registration, a similarity measure is computed of first and second images (4, 6) offset at a plurality of relative axial offsets (30). A starting relative axial offset (40) between the first and second images is identified based on the computed similarity measures. An iterative image registration process is performed to relatively register the first and second images (4, 6) using the identified starting relative axial offset between the first and second images as an initial condition for the iterative image registration process. A starting relative in-slice offset (42) may also be identified as an in-slice offset effective to align corresponding slices of the first and second images (4, 6) offset at the starting relative axial offset (40), the identified starting relative in-slice offset also being used as an initial condition for the iterative image registration process.
摘要翻译：在图像配准中，计算在多个相对轴向偏移（30）处偏移的第一和第二图像（4,6）的相似性度量。基于所计算的相似性度量来识别第一和第二图像之间的起始相对轴向偏移（40）。执行迭代图像注册处理以使用所识别的第一和第二图像之间的起始相对轴向偏移来相对地注册第一和第二图像（4,6）作为迭代图像注册处理的初始条件。起始相对片内偏移（42）也可以被识别为有效地对准在起始相对轴向偏移（40）处偏移的第一和第二图像（4,6）的对应切片的片内偏移，所识别的起始相对片内偏移也被用作迭代图像配准过程的初始条件。

4. 发明授权

US08280483B2 Multi-modality medical image viewing 有权
标题翻译：多模态医学图像观看
公开(公告)号：US08280483B2
公开(公告)日：2012-10-02
申请号：US11424147
申请日：2006-06-14
申请人： Yang-Ming Zhu , Xiangyu Wu , Charles A. Nortmann , Ronald W. Sukalac , Steven M. Cochoff , L. Alan Love , Richard Cheng-Hsiu Chen , Chris A. Dauterman , Madhavi Ahuja , Dawn M. Maniawski
发明人： Yang-Ming Zhu , Xiangyu Wu , Charles A. Nortmann , Ronald W. Sukalac , Steven M. Cochoff , L. Alan Love , Richard Cheng-Hsiu Chen , Chris A. Dauterman , Madhavi Ahuja , Dawn M. Maniawski
IPC分类号： A61B5/05
CPC分类号： G16H30/20 , A61B5/05 , A61B6/463 , G06F17/30899 , G06F17/30905 , G06F19/00 , G06F19/321 , G06T2200/24 , G16H30/00 , G16H30/40 , G16H40/63
摘要： A medical imaging system (10) comprises one or more displays (66). A viewer device (86) generates an interactive user interface screen (80) on the display (66), which viewer device (86) enables a user to simultaneously inspect selected image data of multiple patients or multiple images.
摘要翻译：医疗成像系统（10）包括一个或多个显示器（66）。观看者设备（86）在显示器（66）上生成交互式用户界面屏幕（80），该观看者设备（86）使得用户能够同时检查多个患者或多个图像的所选图像数据。

5. 发明申请

US20120019548A1 PIXEL-FEATURE HYBRID FUSION FOR PET/CT IMAGES 有权
标题翻译：用于PET / CT图像的PIXEL-FEETURE混合融合
公开(公告)号：US20120019548A1
公开(公告)日：2012-01-26
申请号：US13145135
申请日：2009-12-23
申请人： Yang-Ming Zhu , Charles A. Nortmann
发明人： Yang-Ming Zhu , Charles A. Nortmann
IPC分类号： G09G5/02
CPC分类号： G06T11/001 , A61B6/037 , G06T15/503
摘要： An image display method comprises: color coding a second image respective to an intensity spectrum with a portion or portions (72, 82, 92) of the intensity spectrum set to be transparent to generate a color coded second image; combining a first image and the color coded second image to generate a fused image; and displaying the fused image. An image display system comprises: an image generating module (50) configured to generate an image by color coding an input image in accordance with a colormap (52) assigning colors to intensities of an intensity spectrum; a colormap modifying module (56) configured to select a portion (72, 82, 92) of the intensity spectrum to be transparent; and a display (42) configured to display the generated image.
摘要翻译：图像显示方法包括：对强度谱进行颜色编码，其中所述强度谱的部分或部分（72,82,92）设置为透明的，以产生颜色编码的第二图像; 组合第一图像和所述颜色编码的第二图像以生成融合图像; 并显示融合图像。一种图像显示系统，包括：图像生成模块，被配置为根据将颜色分配给强度谱强度的色彩图像（52），通过对输入图像进行彩色编码来生成图像; 配置为选择所述强度谱的部分（72,82,92）为透明的色板修改模块（56）; 以及被配置为显示所生成的图像的显示器（42）。

6. 发明授权

US06775405B1 Image registration system and method using cross-entropy optimization 有权
标题翻译：使用交叉熵优化的图像配准系统和方法
公开(公告)号：US06775405B1
公开(公告)日：2004-08-10
申请号：US09676613
申请日：2000-09-29
申请人： Yang-Ming Zhu
发明人： Yang-Ming Zhu
IPC分类号： G06K900
CPC分类号： G06T3/0068 , G06K9/6212 , G06T7/35 , G06T2207/30004
摘要： An image registration system and method employs a registration processor (130) to find an optimal registration of two volumetric images (110, 112) by finding a spatial orientation that optimizes the statistical measure cross-entropy. The cross-entropy can be minimized where one or more likely or reasonably good a priori estimations of the true joint probability density function (pdf) of voxel value pairs are available. Where such an estimate is not available, the joint pdf for one or more known incorrect spatial arrangements (e.g., based on prior misregistrations), can be used as the prior pdf estimate(s). Since the prior pdf estimate(s) are unlikely to be the true pdf, a spatial orientation maximizing the cross-entropy is found. Likely and unlikely prior pdf estimations can also be used together to register images. The transformation that optimizes the cross entropy provides an optimal registration, and the parameters for the optimized transform are output to memory (150) for use by a display system (160) in aligning the images for display as a fused or composite image.
摘要翻译：图像配准系统和方法使用注册处理器（130）通过找到优化统计测量交叉熵的空间取向来找到两个体积图像（110,112）的最佳配准。如果体素值对的真实联合概率密度函数（pdf）的一个或多个可能或相当好的先验估计可用，则可以最小化交叉熵。在这种估计不可用的情况下，可以使用关于一个或多个已知不正确的空间布置（例如，基于先前的不对准）的联合pdf作为先前的pdf估计。由于以前的pdf估计不太可能是真正的pdf，所以发现了最大化交叉熵的空间方向。可能和不太可能的以前的pdf估计也可以一起用于注册图像。优化交叉熵的变换提供了最佳配准，并且优化变换的参数被输出到存储器（150），供显示系统（160）使图像对准以便显示为融合或合成图像。

7. 发明授权

US06728424B1 Imaging registration system and method using likelihood maximization 有权
标题翻译：使用似然最大化的成像注册系统和方法
公开(公告)号：US06728424B1
公开(公告)日：2004-04-27
申请号：US09663803
申请日：2000-09-15
申请人： Yang-Ming Zhu , Steven M. Cochoff
发明人： Yang-Ming Zhu , Steven M. Cochoff
IPC分类号： G06K932
CPC分类号： G06T3/0068 , G06T7/33 , G06T7/35
摘要： An image processing system and method employs a registration processor (130) to calculate a statistical measure of likelihood for two volumetric images (110, 112). The likelihood is calculated based on an assumption that the voxel values in two images in registration are probabilitically related. The likelihood is calculated for a plurality of relative transformations in iterative fashion until a transformation that maximizes the likelihood is found. The transformation that maximizes the likelihood provides an optimal registration and the parameters for the optimized transform are output to memory (150) for use by a display system (160) in aligning the images for display as a fused or composite image. If statistics about the relationship between the involved images are known, a mutation probability can be derived and used in the likelihood calculation. If there is no such prior knowledge, the mutation probability can be estimated purely from the image data. All voxel pairs in the overlapping volume or, alternatively, a portion of it can be used to compute the likelihood. The optimized likelihood has a simple and less abstract interpretation and can be further used to provide an indication of the quality of the registration.
摘要翻译：图像处理系统和方法使用注册处理器（130）来计算两个体积图像（110,112）的似然性的统计度量。基于假设注册中的两个图像中的体素值是概率相关的，计算似然性。以迭代的方式计算多个相对变换的似然性，直到找到使可能性最大化的变换。使可能性最大化的变换提供了最佳注册，并且用于优化的变换的参数被输出到存储器（150），以供显示系统（160）将图像对准以用于显示为融合或合成图像。如果涉及图像之间的关系的统计数据是已知的，则可以导出变异概率并在可能性计算中使用。如果没有这样的现有知识，则可以纯粹地从图像数据估计突变概率。重叠卷中的所有体素对，或者替代地，其一部分可以用于计算似然性。优化的可能性具有简单且较少抽象的解释，并且可以进一步用于提供注册质量的指示。

8. 发明授权

US09123122B2 Removing an object support from imaging data 有权
标题翻译：从成像数据中删除对象支持
公开(公告)号：US09123122B2
公开(公告)日：2015-09-01
申请号：US13813706
申请日：2011-07-25
申请人： Yang-Ming Zhu , Steven M Cochoff , Ronald Sukalac
发明人： Yang-Ming Zhu , Steven M Cochoff , Ronald Sukalac
IPC分类号： G06K9/00 , G06T7/00 , A61B5/05
CPC分类号： G06T7/0083 , G06T7/12 , G06T7/136 , G06T7/174 , G06T2207/10081 , G06T2207/10104 , G06T2207/20061 , G06T2207/30004
摘要： A method and system for removing an object support from imaging data such as CT imaging data are provided. The automatic or semi-automatic removal process comprises identifying and locating the top edge of the object support in sagittal imaging plane data, and then removing the object support from transverse or volumetric imaging data.
摘要翻译：提供了一种用于从诸如CT成像数据的成像数据中去除对象支持的方法和系统。自动或半自动去除过程包括在矢状成像平面数据中识别和定位对象支撑的顶部边缘，然后从横向或体积成像数据中去除对象支撑。

9. 发明申请

US20120320093A1 MULTI-MODALITY MEDICAL IMAGE VIEWING 审中-公开
公开(公告)号：US20120320093A1
公开(公告)日：2012-12-20
申请号：US13593556
申请日：2012-08-24
申请人： Yang-Ming ZHU , Xiangyu WU , Charles A. NORTMANN , Ronald W. SUKALAC , Steven M. COCHOFF , L. Alan LOVE , Richard Cheng-Hsiu CHEN , Chris A. DAUTERMAN , Madhavi AHUJA , Dawn M. MANIAWSKI
发明人： Yang-Ming ZHU , Xiangyu WU , Charles A. NORTMANN , Ronald W. SUKALAC , Steven M. COCHOFF , L. Alan LOVE , Richard Cheng-Hsiu CHEN , Chris A. DAUTERMAN , Madhavi AHUJA , Dawn M. MANIAWSKI
IPC分类号： G09G5/00
CPC分类号： G16H30/20 , A61B5/05 , A61B6/463 , G06F17/30899 , G06F17/30905 , G06F19/00 , G06F19/321 , G06T2200/24 , G16H30/00 , G16H30/40 , G16H40/63
摘要： A medical imaging system (10) comprises one or more displays (66). A viewer device (86) generates an interactive user interface screen (80) on the display (66), which viewer device (86) enables a user to simultaneously inspect selected image data of multiple patients or multiple images.

10. 发明申请

US20110116701A1 AUTOMATIC PRE-ALIGNMENT FOR REGISTRATION OF MEDICAL IMAGES 失效
标题翻译：医学图像注册的自动预对齐
公开(公告)号：US20110116701A1
公开(公告)日：2011-05-19
申请号：US13054109
申请日：2009-07-20
申请人： Yang-Ming Zhu , Steven M. Cochoff , Cheng-Hsiu Chen
发明人： Yang-Ming Zhu , Steven M. Cochoff , Cheng-Hsiu Chen
IPC分类号： G06K9/32 , G06K9/00
CPC分类号： G06T7/38 , G06T2200/04 , G06T2207/10081 , G06T2207/10104 , G06T2207/10136 , G06T2207/20076 , G06T2207/30196
摘要： In image registration, a similarity measure is computed of first and second images (4, 6) offset at a plurality of relative axial offsets (30). A starting relative axial offset (40) between the first and second images is identified based on the computed similarity measures. An iterative image registration process is performed to relatively register the first and second images (4, 6) using the identified starting relative axial offset between the first and second images as an initial condition for the iterative image registration process. A starting relative in-slice offset (42) may also be identified as an in-slice offset effective to align corresponding slices of the first and second images (4, 6) offset at the starting relative axial offset (40), the identified starting relative in-slice offset also being used as an initial condition for the iterative image registration process.
摘要翻译：在图像配准中，计算在多个相对轴向偏移（30）处偏移的第一和第二图像（4,6）的相似性度量。基于所计算的相似性度量来识别第一和第二图像之间的起始相对轴向偏移（40）。执行迭代图像注册处理以使用所识别的第一和第二图像之间的起始相对轴向偏移来相对地注册第一和第二图像（4,6）作为迭代图像注册处理的初始条件。起始相对片内偏移（42）也可以被识别为有效地对准在起始相对轴向偏移（40）处偏移的第一和第二图像（4,6）的对应切片的片内偏移，所识别的起始相对片内偏移也被用作迭代图像配准过程的初始条件。

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