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1. 外观设计

USD679958S1 Pet food container 有权
公开(公告)号：USD679958S1
公开(公告)日：2013-04-16
申请号：US29415426
申请日：2012-03-09
申请人： Frank Yang , Tzu-Hao Wei , Di-Fong Chang , Po-Ling Huang , Myk Lum , Xun Ye
设计人： Frank Yang , Tzu-Hao Wei , Di-Fong Chang , Po-Ling Huang , Myk Lum , Xun Ye

2. 发明授权

US09422598B2 Method and kit for the prognosis of colorectal cancer 有权
标题翻译：结直肠癌预后的方法和试剂盒
公开(公告)号：US09422598B2
公开(公告)日：2016-08-23
申请号：US13698219
申请日：2010-06-04
申请人： Xun Ye , Fei Wu , Qinghua Xu , Xia Meng , Bruno Mougin , Fang Liu
发明人： Xun Ye , Fei Wu , Qinghua Xu , Xia Meng , Bruno Mougin , Fang Liu
IPC分类号： C07H21/04 , C12Q1/68 , C40B40/06
CPC分类号： C12Q1/6886 , C12Q1/6837 , C12Q2600/112 , C12Q2600/118 , C12Q2600/158 , C40B40/06
摘要： A method and kit for the prognosis of colorectal cancer where the method includes the steps of: a) obtaining a peripheral blood sample and extracting total RNA from the sample, b) contacting the total RNA with at least one reagent specific for at least one NK cell gene and no more than 25 specific reagents for 25 NK cell genes, c) determining the expression level of at least one and at most 25 NK cell genes to obtain an expression profile for the patient, d) analyzing the expression profile with expression profiles previously clinically classified as a good prognosis and as a poor prognosis, wherein if the expression profile is clustered with the poor prognosis profiles, then the patient is determined to have a poor prognosis, and if the expression profile is clustered with the good prognosis profiles, then the patient is determined to have a good prognosis.
摘要翻译：一种用于结肠直肠癌预后的方法和试剂盒，其中所述方法包括以下步骤：a）获得外周血样品并从样品中提取总RNA，b）使总RNA与至少一种特异于至少一种NK的试剂接触细胞基因和不超过25个特异性试剂用于25个NK细胞基因，c）确定至少一个和至多25个NK细胞基因的表达水平以获得患者的表达谱，d）用表达谱分析表达谱以前临床分类为良好的预后和不良预后，其中如果表达谱具有不良预后特征，则确定患者的预后不良，并且如果表达谱具有良好的预后特征，那么确定患者有良好的预后。

3. 发明申请

US20130072401A1 METHOD AND KIT FOR THE PROGNOSIS OF COLORECTAL CANCER 有权
标题翻译：用于预防癌症的方法和工具包
公开(公告)号：US20130072401A1
公开(公告)日：2013-03-21
申请号：US13698219
申请日：2010-06-04
申请人： Xun Ye , Fei Wu , Qinghua Xu , Xia Meng , Bruno Mougin , Fang Liu
发明人： Xun Ye , Fei Wu , Qinghua Xu , Xia Meng , Bruno Mougin , Fang Liu
IPC分类号： C12Q1/68 , C40B40/06
CPC分类号： C12Q1/6886 , C12Q1/6837 , C12Q2600/112 , C12Q2600/118 , C12Q2600/158 , C40B40/06
摘要： A method and kit for the prognosis of colorectal cancer where the method includes the steps of: a) obtaining a peripheral blood sample and extracting total RNA from the sample, b) contacting the total RNA with at least one reagent specific for at least one NK cell gene and no more than 25 specific reagents for 25 NK cell genes, c) determining the expression level of at least one and at most 25 NK cell genes to obtain an expression profile for the patient, d) analyzing the expression profile with expression profiles previously clinically classified as a good prognosis and as a poor prognosis, wherein if the expression profile is clustered with the poor prognosis profiles, then the patient is determined to have a poor prognosis, and if the expression profile is clustered with the good prognosis profiles, then the patient is determined to have a good prognosis.
摘要翻译：一种用于结肠直肠癌预后的方法和试剂盒，其中所述方法包括以下步骤：a）获得外周血样品并从样品中提取总RNA，b）使总RNA与至少一种特异于至少一种NK的试剂接触细胞基因和不超过25个特异性试剂用于25个NK细胞基因，c）确定至少一个和至多25个NK细胞基因的表达水平以获得患者的表达谱，d）用表达谱分析表达谱以前临床分类为良好的预后和不良预后，其中如果表达谱具有不良预后特征，则确定患者的预后不良，并且如果表达谱具有良好的预后特征，那么确定患者有良好的预后。

4. 发明授权

US09689041B2 Method and kit for determining in vitro the probability for an individual to suffer from colorectal cancer 有权
公开(公告)号：US09689041B2
公开(公告)日：2017-06-27
申请号：US14007439
申请日：2012-03-23
申请人： Xun Ye , Fei Wu , Qinghua Xu , Fang Liu , Xia Meng , Bruno Mougin
发明人： Xun Ye , Fei Wu , Qinghua Xu , Fang Liu , Xia Meng , Bruno Mougin
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/158
摘要： The present invention provides a method for determining in vitro, in a peripheral blood sample, the probability for an individual to suffer from a colorectal cancer, using the comparison of the amount of expression products of nucleic acids of genes of the individual to be tested with the amount of expression products of nucleic acids of the same genes obtained from a CRC group of patients constituting the positive control and with the amount of expression products of nucleic acids of the same genes obtained from a CNC group of individuals constituting the negative control; and a kit comprising specific binding partners for said expression products.

5. 发明授权

US09410188B2 Method and kit for discriminating between breast cancer and benign breast disease 有权
标题翻译：用于区分乳腺癌和良性乳腺疾病的方法和试剂盒
公开(公告)号：US09410188B2
公开(公告)日：2016-08-09
申请号：US13696937
申请日：2010-05-28
申请人： Xun Ye , Fei Wu , Qinghua Xu , Xia Meng , Bruno Mougin
发明人： Xun Ye , Fei Wu , Qinghua Xu , Xia Meng , Bruno Mougin
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6837 , C12Q1/6886 , C12Q2600/112 , C12Q2600/158
摘要： A method and kit are related to discriminating between breast cancer and benign breast disease by the determination of the expression level of at least one target gene including a nucleic acid sequence selected from the nucleic acid sequences set forth in SEQ ID NOs: 1, 2 or 3, 4 and 5 or 6 to obtain an expression profile for the patient, and the comparison of the expression profile of the patient with expression profiles of target genes from patients previously clinically classified as breast cancer and expression profiles of target genes from patients previously clinically classified as benign breast disease.
摘要翻译：一种方法和试剂盒涉及通过测定至少一种靶基因的表达水平来区分乳腺癌和良性乳腺疾病，所述至少一种靶基因包括选自SEQ ID NO：1,2所示的核酸序列的核酸序列，或 3,4和5或6以获得患者的表达谱，并且将患者的表达谱与先前临床分类为乳腺癌的患者的靶基因的表达谱和先前临床患者的靶基因的表达谱进行比较归为良性乳腺疾病。

6. 发明申请

US20140057802A1 METHOD AND KIT FOR DETERMINING IN VITRO THE PROBABILITY FOR AN INDIVIDUAL TO SUFFER FROM COLORECTAL CANCER 有权
标题翻译：用于确定个体对彩色癌症的可能性的方法和工具
公开(公告)号：US20140057802A1
公开(公告)日：2014-02-27
申请号：US14007439
申请日：2012-03-23
申请人： Xun Ye , Fei Wu , Qinghua Xu , Fang Liu , Xia Meng , Bruno Mougin
发明人： Xun Ye , Fei Wu , Qinghua Xu , Fang Liu , Xia Meng , Bruno Mougin
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/158
摘要： The present invention provides a method for determining in vitro, in a peripheral blood sample, the probability for an individual to suffer from a colorectal cancer, using the comparison of the amount of expression products of nucleic acids of genes of the individual to be tested with the amount of expression products of nucleic acids of the same genes obtained from a CRC group of patients constituting the positive control and with the amount of expression products of nucleic acids of the same genes obtained from a CNC group of individuals constituting the negative control; and a kit comprising specific binding partners for said expression products.
摘要翻译：本发明提供了一种用于在外周血样品中测定个体遭受结肠直肠癌的可能性的方法，该方法使用待测个体的基因的核酸的表达产物的量与从构成阳性对照的CRC组获得的相同基因的核酸的表达产物的量以及从构成阴性对照的个体的CNC组获得的相同基因的核酸的表达产物的量; 以及包含所述表达产物的特异性结合伴侣的试剂盒。

7. 发明申请

US20130173077A1 POWER SWITCH HAVING SERIES-CONNECTED SWITCHING STAGES 审中-公开
标题翻译：具有串联连接开关级的电源开关
公开(公告)号：US20130173077A1
公开(公告)日：2013-07-04
申请号：US13339790
申请日：2011-12-29
申请人： Zu Xun Ye , Joseph Gerard Garofalo , Ming Chen , ChunXuan Pei , Xiaopeng Xie
发明人： Zu Xun Ye , Joseph Gerard Garofalo , Ming Chen , ChunXuan Pei , Xiaopeng Xie
IPC分类号： G05F5/00 , H01H47/00
CPC分类号： G06F1/30 , G06F1/26 , G06F1/3268 , G06F1/3287 , G06F3/0625 , Y02D10/154 , Y02D10/171 , Y10T307/747
摘要： A power switch of a processing device comprises a plurality of series-connected switching stages, with each switching stage comprising a plurality of parallel-connected switching devices and an inverter chain. The switching devices are coupled between a power supply input and a power supply output of the power switch. Each of the switching devices of a given one of the switching stages is driven by an output of a corresponding one of the inverters of the inverter chain of that stage. A control input of the first switching stage receives a control signal for controlling a state of the power switch, and a control input of each remaining switching stage is driven by a control output of an immediately preceding switching stage. The switching devices in one or more of the switching stages are configured to have different switching characteristics than the switching devices in at least one other stage.
摘要翻译：处理装置的电源开关包括多个串联的开关级，每个开关级包括多个并联的开关装置和逆变器链。开关器件耦合在电源输入端和电源开关的电源输出端之间。给定一个开关级的开关装置中的每一个由该级的反相器链的相应一个反相器的输出驱动。第一开关级的控制输入接收用于控制电源开关的状态的控制信号，并且通过紧接在前的切换级的控制输出来驱动每个剩余切换级的控制输入。一个或多个开关级中的开关器件被配置为具有与至少一个其它级中的开关器件不同的开关特性。

8. 发明申请

US20130072399A1 METHOD AND KIT FOR DISCRIMINATING BETWEEN BREAST CANCER AND BENIGN BREAST DISEASE 有权
标题翻译：用于鉴别乳腺癌和勃起乳腺疾病之间的方法和工具包
公开(公告)号：US20130072399A1
公开(公告)日：2013-03-21
申请号：US13696937
申请日：2010-05-28
申请人： Xun Ye , Fei Wu , Qinghua Xu , Xia Meng , Bruno Mougin
发明人： Xun Ye , Fei Wu , Qinghua Xu , Xia Meng , Bruno Mougin
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6837 , C12Q1/6886 , C12Q2600/112 , C12Q2600/158
摘要： A method and kit are related to discriminating between breast cancer and benign breast disease by the determination of the expression level of at least one target gene including a nucleic acid sequence selected from the nucleic acid sequences set forth in SEQ ID NOs: 1, 2 or 3, 4 and 5 or 6 to obtain an expression profile for the patient, and the comparison of the expression profile of the patient with expression profiles of target genes from patients previously clinically classified as breast cancer and expression profiles of target genes from patients previously clinically classified as benign breast disease.
摘要翻译：一种方法和试剂盒涉及通过测定至少一种靶基因的表达水平来区分乳腺癌和良性乳腺疾病，所述至少一种靶基因包括选自SEQ ID NO：1,2所示的核酸序列的核酸序列，或 3,4和5或6以获得患者的表达谱，并且将患者的表达谱与先前临床分类为乳腺癌的患者的靶基因的表达谱和先前临床患者的靶基因的表达谱进行比较归为良性乳腺疾病。

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