专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US08563537B2 Camptothecin derivatives as chemoradiosensitizing agents 有权
标题翻译：喜树碱衍生物作为化学放射增敏剂
公开(公告)号：US08563537B2
公开(公告)日：2013-10-22
申请号：US12124712
申请日：2008-07-29
申请人： Li-Xi Yang
发明人： Li-Xi Yang
IPC分类号： A61K31/33
CPC分类号： C07D491/22 , A61K45/06
摘要： Camptothecin-based compounds are useful for treating a neoplasm in mammalian subjects by administering such compound to the subjects in combination with radiotherapy, i.e., the treatment of tumors with radioactive substances or radiation from a source external to the subject. Camptothecin-based compounds are modified by positioning at least one electron-affinic group around the camptothecin structure to enhance their value in combination with radiotherapy. New Camptothecin-based compounds are disclosed that are useful for treating cancer by administering the novel compounds alone or in combination with radiotherapy.
摘要翻译：喜树碱类化合物可用于治疗哺乳动物受试者的肿瘤，其通过与受试者联合放射治疗，即用放射性物质治疗肿瘤或从受试者外部的来源辐射来治疗肿瘤。通过在喜树碱结构周围定位至少一个电子亲和基团来改善喜树碱类化合物，以增强其与放射治疗相结合的价值。公开了新的喜树碱类化合物，其可用于通过单独施用新化合物或与放射治疗组合来治疗癌症。

2. 发明授权

US08432916B2 Method and router for implementing mirroring 有权
标题翻译：实现镜像的方法和路由器
公开(公告)号：US08432916B2
公开(公告)日：2013-04-30
申请号：US13258002
申请日：2009-08-24
申请人： Ning Li , Xi Yang , Qing Wang
发明人： Ning Li , Xi Yang , Qing Wang
IPC分类号： H04L12/28
CPC分类号： G06F11/2071
摘要： A method and router for implementing mirroring, said method including: configuring a remote mirroring port on a source router, establishing a corresponding layer two virtual interface, and specifying a data stream requiring mirroring and a corresponding physical egress port; establishing a layer two virtual interface corresponding to the layer two virtual interface of said source router on a destination router; forming one VPWS tunnel between the layer two virtual interfaces of said source router and said destination router; filtering out the mirroring data stream from the packet received at the remote mirroring port of said source router, and sending obtained mirroring packet from the physical egress port on said source router to said destination router; searching the layer two virtual interface on said destination router after receiving mirroring packet, and sending mirroring packet without a label from its corresponding physical port to a monitoring port, thereby implementing router remote mirroring.
摘要翻译：一种用于实现镜像的方法和路由器，所述方法包括：在源路由器上配置远程镜像端口，建立相应的第二层虚拟接口，并指定需要镜像的数据流和相应的物理出口; 在目的路由器上建立对应于所述源路由器的第二层虚拟接口的二层虚拟接口; 在所述源路由器的所述第二层虚拟接口和所述目的路由器之间形成一个VPWS隧道; 从所述源路由器的远程镜像端口接收的分组过滤出镜像数据流，并将获得的镜像分组从所述源路由器上的物理出口端口发送到所述目的路由器; 在接收到镜像报文后，在目的路由器上查找二层虚拟接口，并将不带标签的镜像报文从对应的物理端口发送到监控端口，从而实现路由器远程镜像。

3. 发明申请

US20130059475A1 USB Connector 审中-公开
标题翻译： USB连接器
公开(公告)号：US20130059475A1
公开(公告)日：2013-03-07
申请号：US13258426
申请日：2010-08-25
申请人： Qingsong Shi , Yanbin Zhang , Ning Liu , Xi Yang
发明人： Qingsong Shi , Yanbin Zhang , Ning Liu , Xi Yang
IPC分类号： H01R24/28
CPC分类号： H01R12/722 , H01R12/707 , H01R13/6581 , H01R13/6597
摘要： The present invention discloses a USB connector, comprising: a USB shell, an insulation spacer, metal sheets with metal weld legs respectively. The metal sheets are installed on the insulation spacer, the metal sheets are configured to be connected to a USB interface of a personal computer, the metal weld legs are connected to a printed circuit board within an external product, and the insulation spacer is fixed in the USB shell; the metal sheets comprise one ground pin, two signal pins and one power supply pin, wherein the ground pin is configured with an extending resilient metal sheet contacted with the USB shell. Widths of the metal sheets and the metal weld legs are widen and thicknesses of the metal sheets and the insulation spacer are thicken, so that the USB connector and the USB interface of the computer are contacted sufficiently, enhancing the ground effect of the USB connector.
摘要翻译：本发明公开了一种USB连接器，包括：USB外壳，绝缘垫片，分别具有金属焊脚的金属片。金属片安装在绝缘垫片上，金属片被配置为连接到个人计算机的USB接口，金属焊脚与外部产品中的印刷电路板连接，绝缘垫片固定在 USB外壳; 金属片包括一个接地引脚，两个信号引脚和一个电源引脚，其中接地引脚配置有与USB外壳接触的延伸的弹性金属片。金属片和金属焊脚的宽度变宽，金属片和绝缘衬垫的厚度增厚，使得USB连接器和计算机的USB接口充分接触，增强了USB连接器的接地效果。

4. 发明授权

US07926542B2 Low stress dewaxing system and method 失效
标题翻译：低应力脱蜡系统及方法
公开(公告)号：US07926542B2
公开(公告)日：2011-04-19
申请号：US12286255
申请日：2008-09-29
申请人： Xi Yang
发明人： Xi Yang
IPC分类号： B22C9/04 , B22C17/00
CPC分类号： B22C9/043
摘要： A system and method for dewaxing is provided. The system includes a ceramic shell mold having a wall. Water is present within the wall of the ceramic shell mold. A wax pattern assembly is located within the ceramic shell mold. A heat source is configured for heating at least a portion of the wall of the ceramic shell mold in order to convert at least a portion of the water within the wall of the ceramic shell mold into steam for use in melting at least a portion of the wax pattern.
摘要翻译：提供了一种用于脱蜡的系统和方法。该系统包括具有壁的陶瓷壳模具。水存在于陶瓷壳模具的壁内。蜡图案组件位于陶瓷壳模具内。热源被配置用于加热陶瓷壳模具的壁的至少一部分，以便将陶瓷壳模具的壁内的至少一部分水转化为蒸汽，以用于熔化至少一部分蜡图案。

5. 发明授权

US07679365B2 Current lead of superconducting magnet of magnetic resonance system 有权
标题翻译：磁共振系统超导磁体的电流引线
公开(公告)号：US07679365B2
公开(公告)日：2010-03-16
申请号：US12022282
申请日：2008-01-30
申请人： Xi Yang Du , Huai Yu Pan , Zhong You Ren , Xing En Yu
发明人： Xi Yang Du , Huai Yu Pan , Zhong You Ren , Xing En Yu
IPC分类号： G01V3/00
CPC分类号： G01R33/3815 , G01R33/3804 , H01F6/065
摘要： A current lead for the superconducting magnet of a magnetic resonance system, the superconducting magnet being refrigerated by a cold head, has a positive current lead and a negative current lead electrically connected to the superconducting magnet for magnetization thereof. The cold head is electrically connected to the superconducting magnet and is used as one of the positive and negative current leads. The cold head is used as the positive current lead or the negative current lead so as to reduce the number of current leads as well as the heat conducted by the current lead, therefore it maintains a stable superconducting environment more efficiently. Furthermore, the cold head and the current lead can be provided in the same conduit without the need to design a separated turret tube and side tube, and the structure of the current leads of the superconducting magnet of the magnetic resonance system is simplified.
摘要翻译：用于冷磁头的超导磁体的磁共振系统的超导磁体的电流引线具有与超导磁体电连接的用于磁化的正电流引线和负电流引线。冷头电连接到超导磁体，并用作正极和负极引线之一。冷头用作正电流引线或负电流引线，以减少电流引线的数量以及电流引线所传导的热量，从而更有效地保持了稳定的超导环境。此外，冷头和电流引线可以设置在相同的管道中，而不需要设计分离的转塔管和侧管，并且简化了磁共振系统的超导磁体的电流引线的结构。

6. 发明授权

US07605262B2 Podophyllotoxin derivatives 有权
标题翻译：鬼臼毒素衍生物
公开(公告)号：US07605262B2
公开(公告)日：2009-10-20
申请号：US12016926
申请日：2008-01-18
申请人： Li-Xi Yang
发明人： Li-Xi Yang
IPC分类号： C07D519/04 , C07D307/00
CPC分类号： C07F9/6561 , C07D493/04
摘要： 4-O esters of podophyllotoxin and 4′-demethylepipodophyllotoxin are provided. The compounds are 4-O esters of an alkanoic acid or substituted alkanoic acid and podophyllotoxin and 4′-demethylepipodophyllotoxin. The compounds are useful for treating cancer.
摘要翻译：提供鬼臼毒素和4'-去甲表鬼臼毒素的4-O酯。这些化合物是链烷酸或取代的链烷酸和鬼臼毒素和4'-去甲表鬼臼毒素的4-O酯。该化合物可用于治疗癌症。

7. 发明授权

US07342114B2 Podophyllotoxin derivatives 有权
标题翻译：鬼臼毒素衍生物
公开(公告)号：US07342114B2
公开(公告)日：2008-03-11
申请号：US10612240
申请日：2003-07-01
申请人： Li-Xi Yang
发明人： Li-Xi Yang
IPC分类号： C07D211/22 , C07D405/00 , C07D307/77
CPC分类号： C07F9/6561 , C07D493/04
摘要： 4-O esters of podophyllotoxin and 4′-demethylepipodophyllotoxin are provided. The compounds are 4-O esters of an alkanoic acid or substituted alkanoic acid and podophyllotoxin and 4′-demethylepipodophyllotoxin. The compounds are useful for treating cancer.
摘要翻译：提供鬼臼毒素和4'-去甲表鬼臼毒素的4-O酯。这些化合物是链烷酸或取代的链烷酸和鬼臼毒素和4'-去甲表鬼臼毒素的4-O酯。该化合物可用于治疗癌症。

8. 发明申请

US20050250795A1 Synthesis of acyclic nucleoside derivatives 失效
标题翻译：无环核苷衍生物的合成
公开(公告)号：US20050250795A1
公开(公告)日：2005-11-10
申请号：US11131646
申请日：2005-05-18
申请人： M. Leanna , Steven Hannick , Michael Rasmussen , Jien-Heh Tien , Lakshmi Bhagavatula , Pulla Singam , Bradley Gates , Lawrence Kolaczkowski , Ramesh Patel , Greg Wayne , Greg Lannoye , Weijiang Zhang , Zhenping Tian , Kirill Lukin , Bikshandarkoil Narayanan , David Riley , Howard Morton , Sou-Jen Chang , Cynthia Curty , Daniel Plata , John Bellettini , Bhadra Shelat , Tiffany Spitz , Cheng-Xi Yang
发明人： M. Leanna , Steven Hannick , Michael Rasmussen , Jien-Heh Tien , Lakshmi Bhagavatula , Pulla Singam , Bradley Gates , Lawrence Kolaczkowski , Ramesh Patel , Greg Wayne , Greg Lannoye , Weijiang Zhang , Zhenping Tian , Kirill Lukin , Bikshandarkoil Narayanan , David Riley , Howard Morton , Sou-Jen Chang , Cynthia Curty , Daniel Plata , John Bellettini , Bhadra Shelat , Tiffany Spitz , Cheng-Xi Yang
IPC分类号： C07D473/18 , A61K31/522 , C07B53/00 , C07B61/00 , C07C303/30 , C07C309/45 , C07C309/73 , C07D473/00 , C07D473/12 , C07D473/32 , C07D473/40
CPC分类号： C07D473/00 , C07C309/73 , C07D473/18 , Y02P20/55
摘要： Methods and novel intermediates for the preparation of acyclic nucleoside derivatives of the formula: where one of R1 and R2 is an amino acid acyl group and the other of R1 and R2 is a —C(O)C3-C21 saturated or monounsaturated, optionally substituted alkyl and R3 is OH or H; or a pharmaceutically acceptable salt thereof.
摘要翻译：用于制备下式的无环核苷衍生物的方法和新型中间体：其中R 1和R 2中的一个是氨基酸酰基，另一个是R _{1和R 2是-C（O）C 3 -C 21饱和或单不饱和的任选取代的烷基和 R 3是OH或H; 或其药学上可接受的盐。}

9. 发明授权

US06845811B2 Reinforced shell mold and method 有权
标题翻译：增强外壳模具及方法
公开(公告)号：US06845811B2
公开(公告)日：2005-01-25
申请号：US10712769
申请日：2003-11-13
申请人： Xi Yang , Boyd A. Mueller
发明人： Xi Yang , Boyd A. Mueller
IPC分类号： B22C1/00 , B22C9/02 , B22C9/04 , B22D21/00 , B22D27/04 , C04B35/66 , C04B35/80 , B22C1/02
CPC分类号： B22C9/04 , B22C13/085 , B22D27/045 , C04B35/117 , C04B35/6316 , C04B35/66 , C04B35/803 , C04B2235/3418 , C04B2235/5232 , C04B2235/526 , C04B2235/5264 , C04B2235/77
摘要： A method of making a ceramic shell mold comprises repeatedly coating a fugitive pattern of an article to be cast with a ceramic slurry layer and applying on the ceramic slurry layer a refractory stucco to form a plurality of ceramic slurry layers and stucco layers on the pattern wherein at least one of the stucco layers is formed by applying discontinuous stucco fiber bundles held together in the bundles by a fugitive binder, which is removed during subsequent firing of the shell mold at elevated temperature.
摘要翻译：制造陶瓷壳模的方法包括用陶瓷浆料层反复涂覆待浇铸制品的短片图案，并在陶瓷浆料层上施加耐火灰泥，以在图案上形成多个陶瓷浆料层和灰泥层，灰泥层中的至少一个是通过在短时间内在模具的高温烧制过程中除去的短时粘结剂施加不均匀的灰泥纤维束而形成的。

10. 发明授权

US06184376B2 Synthesis of acyclic nucleoside derivatives 有权
标题翻译：无环核苷衍生物的合成
公开(公告)号：US06184376B2
公开(公告)日：2001-02-06
申请号：US09130214
申请日：1998-08-06
申请人： M. Robert Leanna , Steven M. Hannick , Michael Rasmussen , Jien-Heh J. Tien , Lakshmi Bhagavatula , Pulla Reddy Singam , Bradley D. Gates , Lawrence Kolaczkowski , Ramesh R. Patel , Greg Wayne , Greg Lannoye , Weijiang Zhang , Zhenping Tian , Kirill A. Lukin , Bikshandarkoil A. Narayanan , David A. Riley , Howard Morton , Sou-Jen Chang , Cynthia B. Curty , Daniel Plata , John Bellettini , Bhadra Shelat , Tiffany Spitz , Cheng-Xi Yang
发明人： M. Robert Leanna , Steven M. Hannick , Michael Rasmussen , Jien-Heh J. Tien , Lakshmi Bhagavatula , Pulla Reddy Singam , Bradley D. Gates , Lawrence Kolaczkowski , Ramesh R. Patel , Greg Wayne , Greg Lannoye , Weijiang Zhang , Zhenping Tian , Kirill A. Lukin , Bikshandarkoil A. Narayanan , David A. Riley , Howard Morton , Sou-Jen Chang , Cynthia B. Curty , Daniel Plata , John Bellettini , Bhadra Shelat , Tiffany Spitz , Cheng-Xi Yang
IPC分类号： C07D47318
CPC分类号： C07D473/00 , C07C309/73 , C07D473/18 , Y02P20/55
摘要： Methods and novel intermediates of the formula: wherein R6 and R7 are lower alkyl or benzyl or R6 and R7 taken together are —CH2CH2—, —CH2CH2CH2— or —CH2CH2CH2CH2CH2—, R8 is C1-C21 alkyl or a C2-C21 monounsaturated alkenyl, which may optionally be substituted with substitution substituents independently selected from the group consisting of hydroxy, C1-C6 alkyl, C1-C6 alkoxy, C1-C6 alkoxy C1-C6 alkyl, C1-C6 alkanoyl, amino, halo, cyano, azido, oxo, mercapto and nitro, and R9 is an alcohol protecting group. The intermediates are useful for the preparation of acyclic nucleoside derivatives of the formula: where one of R1 and R2 is an amino acid acyl group and the other of R1 and R2 is a —C(O)C3-C21 saturated or monounsaturated, optionally substituted alkyl and R3 is OH or H; or a pharmaceutically acceptable salt thereof.
摘要翻译：下式的方法和新型中间体：其中R6和R7是低级烷基或苄基或R6和R7一起是-CH 2 CH 2 - ， - CH 2 CH 2 CH 2 - 或-CH 2 CH 2 CH 2 CH 2 CH 2 - ，R 8是C 1 -C 21烷基或C 2 -C 21单不饱和链烯基，其可以任选地被独立地选自羟基，C 1 -C 6烷基，C 1 -C 6烷氧基，C 1 -C 6烷氧基C 1 -C 6烷基，C 1 -C 6烷酰基，氨基，卤素，氰基，叠氮基，氧代，巯基和硝基，R9是醇保护基。中间体可用于制备下式的无环核苷衍生物：其中R 1和R 2中的一个是氨基酸酰基，R 1和R 2中的另一个是-C（O）C 3 -C 21饱和或单不饱和的，任选取代的烷基和R 3是OH或H; 或其药学上可接受的盐。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式