专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20120078871A1 DETECTING DUPLICATE AND NEAR-DUPLICATE FILES 审中-公开
标题翻译：检测重复和近似文件
公开(公告)号：US20120078871A1
公开(公告)日：2012-03-29
申请号：US13313913
申请日：2011-12-07
申请人： William Pugh , Monika H. Henzinger
发明人： William Pugh , Monika H. Henzinger
IPC分类号： G06F17/30
CPC分类号： G06F16/951 , G06F16/355 , Y10S707/99933 , Y10S707/99935 , Y10S707/99936 , Y10S707/99943
摘要： Improved duplicate and near-duplicate detection techniques may assign a number of fingerprints to a given document by (i) extracting parts from the document, (ii) assigning the extracted parts to one or more of a predetermined number of lists, and (iii) generating a fingerprint from each of the populated lists. Two documents may be considered to be near-duplicates if any one of their fingerprints match.
摘要翻译：改进的重复和近似重复的检测技术可以通过（i）从文档中提取部分，（ii）将提取的部分分配给预定数目的列表中的一个或多个来分配给定文档的许多指纹，以及（iii）从每个填充列表生成指纹。如果任何一个指纹匹配，两个文件可能被认为是近似重复的。

2. 发明申请

US20110202193A1 Managing Power Utilized Within A Local Power Network 有权
标题翻译：管理本地电力网中使用的电力
公开(公告)号：US20110202193A1
公开(公告)日：2011-08-18
申请号：US12706975
申请日：2010-02-17
申请人： Jason Craig , Richard Daniel Albarran , William Pugh , Kevin Cassidy
发明人： Jason Craig , Richard Daniel Albarran , William Pugh , Kevin Cassidy
IPC分类号： G06F1/32 , G06Q40/00
CPC分类号： G05F1/66 , G05B13/02 , G05B15/02 , G06F3/04842 , G06Q10/00 , G06Q50/06 , H02J3/14 , H02J13/0062 , Y02B70/3225 , Y02B90/2638 , Y04S20/222 , Y04S40/124
摘要： Power utilized in a local power network may be managed. The local power network may include a power management system. The power management system may communicate with one or more of a circuit controller, a switch controller, and/or an outlet controller in order to manage power utilization.
摘要翻译：可以管理在本地电力网络中使用的功率。本地电力网可以包括电力管理系统。电源管理系统可以与电路控制器，开关控制器和/或插座控制器中的一个或多个通信，以便管理电力利用。

3. 发明申请

US20110100879A1 IMPROVEMENTS IN OR RELATING TO FILTERS 审中-公开
标题翻译：改进或相关过滤器
公开(公告)号：US20110100879A1
公开(公告)日：2011-05-05
申请号：US12736426
申请日：2009-04-03
申请人： Alisdair Quentin Clark , Ricci Middleton , Peter Robert William Pugh
发明人： Alisdair Quentin Clark , Ricci Middleton , Peter Robert William Pugh
IPC分类号： C10G29/04 , B03C1/14
CPC分类号： B03C1/286 , B03C2201/18
摘要： A magnetic filter device and method for using same, for removing ferromagnetic particles from a liquid, which device comprises a vessel having an inlet for liquid to flow into the vessel and an outlet for the liquid to flow out of the vessel, and the vessel having one or more magnets suspended therein for removing ferromagnetic particles from liquid flowing between the inlet and outlet, characterised in that: the vessel is a horizontal pipe with the inlet at one end and the outlet at the other end, the magnets are suspended transverse to the longitudinal axis of the pipe in one or more sets, and the vessel has one or more helical flow generators which in use, generate helical flow of the liquid as it flows between the inlet and outlet, and/or one or more turbulent flow generators which in use, generate turbulent flow of the liquid as it flows between the inlet and outlet. The helical and/or turbulent flow of the liquid may mitigate the potential problems of liquid and/or particles by-passing the magnet or magnets, for example arising from laminar flow of the liquid and/or uneven distribution of particles in the liquid.
摘要翻译：一种磁性过滤装置及其使用方法，用于从液体中除去铁磁颗粒，该装置包括具有用于液体流入容器的入口和用于液体流出容器的出口的容器，并且该容器具有悬挂在其中的一个或多个磁体用于从在入口和出口之间流动的液体中除去铁磁颗粒，其特征在于：容器是水平管，其一端具有入口，在另一端具有出口，磁体横向于管子的纵向轴线在一个或多个组中，并且容器具有一个或多个螺旋流发生器，其在使用时在液体在入口和出口之间流动时产生螺旋流，和/或一个或多个湍流发生器，在使用中，当液体在入口和出口之间流动时，会产生液体的湍流。液体的螺旋和/或湍流可以减轻液体和/或颗粒绕过磁体或磁体的潜在问题，例如由于液体的层流和/或液体中颗粒的不均匀分布引起。

4. 发明申请

US20100272726A1 Assays, methods and means 有权
标题翻译：测定方法和方法
公开(公告)号：US20100272726A1
公开(公告)日：2010-10-28
申请号：US12654993
申请日：2010-01-12
申请人： Patrick Henry Maxwell , Christopher William Pugh , Peter John Ratcliffe , Christopher Joseph Schofield
发明人： Patrick Henry Maxwell , Christopher William Pugh , Peter John Ratcliffe , Christopher Joseph Schofield
IPC分类号： A61K38/16 , A61K39/395 , G01N33/573 , C12Q1/34 , C12N9/14 , C12N15/63 , A61K31/7088 , A61K31/44 , A61K31/225 , A61K31/195 , C07K7/08 , C07K14/435 , C07K16/00 , C07H21/04 , C07H21/02 , C07D213/80 , C07C229/00
CPC分类号： A61K31/455 , A01K2217/05 , A61K31/137 , A61K31/14 , A61K31/165 , A61K31/166 , A61K31/185 , A61K31/192 , A61K31/194 , A61K31/195 , A61K31/197 , A61K31/198 , A61K31/21 , A61K31/221 , A61K31/223 , A61K31/225 , A61K31/235 , A61K31/24 , A61K31/265 , A61K31/327 , A61K31/44 , A61K31/4412 , A61K38/00 , A61K39/3955 , C07C235/80 , C07C323/60 , C07C327/32 , C07D213/80 , C07D213/81 , C07D213/82 , C07K14/4702 , C07K16/40 , C07K2317/30 , C12N9/0071 , C12Q1/26 , C12Q1/34 , G01N33/573 , G01N2333/90245 , G01N2500/04 , G01N2500/20
摘要： A novel class of hydroxylases is described having the amino acid sequence of SEQ ID NO: 2, 4, 6 and 8, and variants and fragments thereof having HIF hydroxylation activity. The polypeptides of the invention have in particular prolyl hydroxylase activity. An assay method monitors the interaction of the HIF hydroxylase with a substrate. Modulators of HIF hydroxylase are provided for use in the treatment of a condition associated with increased or decreased HIF levels or activity or for the treatment of a condition where it is desirable to modulate HIF levels or activity.
摘要翻译：描述了一类新型的羟化酶，其具有SEQ ID NO：2,4,6和8的氨基酸序列，其变体和片段具有HIF羟基化活性。本发明的多肽特别是脯氨酰羟化酶活性。测定方法监测HIF羟化酶与底物的相互作用。提供HIF羟化酶的调节剂用于治疗与增加或降低的HIF水平或活性有关的病症，或用于治疗期望调节HIF水平或活性的病症。

5. 发明授权

US07544480B2 Assays for modulators of asparaginyl hydroxylase 失效
标题翻译：天冬酰胺酰羟化酶调节剂的测定
公开(公告)号：US07544480B2
公开(公告)日：2009-06-09
申请号：US10515419
申请日：2003-05-23
申请人： Christopher William Pugh , Jonathan Mark Gleadle , Peter John Ratcliffe , Christopher Joseph Schofield , Luke Alexander McNeill
发明人： Christopher William Pugh , Jonathan Mark Gleadle , Peter John Ratcliffe , Christopher Joseph Schofield , Luke Alexander McNeill
IPC分类号： C12Q1/26
CPC分类号： C12N9/0071 , C12Q1/26 , G01N33/6893 , G01N2333/4703 , G01N2500/04
摘要： A method of identifying an agent which modulates hydroxylation of hypoxia inducible factor (HIF), comprises contacting a HIF asparagine hydroxylase and a test substance in the presence of a substrate of the hydroxylase under conditions in which asparagine in the substrate is hydroxylated in the absence of the test substance; and determining hydroxylation of the substrate. Preferably the substrate is a HIF polypeptide comprising HIF-1α, a fragment thereof comprising Asn 803 of HIF-1α or a peptide analogue of HIF-1α or fragment thereof comprising an asparagine equivalent to Asn 803 of HIF-1α and wherein hydroxylation of Asn 803 or of a said equivalent asparagine is determined.
摘要翻译：一种鉴定调节缺氧诱导因子（HIF）的羟基化的试剂的方法，包括在不存在羟基化酶的基质的天冬酰胺被羟基化的条件下，在羟化酶的底物存在下，使HIF天冬酰胺羟化酶和测试物质接触测试物质; 并测定底物的羟基化。优选地，底物是包含HIF-1α的HIF多肽，其包含HIF-1α的Asn 803的片段或HIF-1α的肽类似物或其片段，其包含与HIF-1α的Asn 803相当的天冬酰胺，并且其中Asn 803的羟基化或所述等同的天冬酰胺。

6. 发明授权

US07366718B1 Detecting duplicate and near-duplicate files 有权
标题翻译：检测重复和近似重复的文件
公开(公告)号：US07366718B1
公开(公告)日：2008-04-29
申请号：US10608468
申请日：2003-06-27
申请人： William Pugh , Monika H. Henzinger
发明人： William Pugh , Monika H. Henzinger
IPC分类号： G06F7/00 , G06F17/30
CPC分类号： G06F17/30864 , G06F17/3071 , Y10S707/99933 , Y10S707/99935 , Y10S707/99936 , Y10S707/99943
摘要： Improved duplicate and near-duplicate detection techniques may assign a number of fingerprints to a given document by (i) extracting parts from the document, (ii) assigning the extracted parts to one or more of a predetermined number of lists, and (iii) generating a fingerprint from each of the populated lists. Two documents may be considered to be near-duplicates if any one of their fingerprints match.
摘要翻译：改进的重复和近似重复的检测技术可以通过（i）从文档中提取部分，（ii）将提取的部分分配给预定数目的列表中的一个或多个来分配给定文档的许多指纹，以及（iii）从每个填充列表生成指纹。如果任何一个指纹匹配，两个文件可能被认为是近似重复的。

7. 发明申请

US20080034351A1 Process for making software diagnostics more efficient by leveraging existing content, human filtering and automated diagnostic tools 审中-公开
标题翻译：利用现有内容，人工过滤和自动诊断工具，使软件诊断更有效率的过程
公开(公告)号：US20080034351A1
公开(公告)日：2008-02-07
申请号：US11768337
申请日：2007-06-26
申请人： William Pugh , Ryan Sweet , Steve Jacobson , Christian Hansson , Ross Jekel , Yongshao Ruan
发明人： William Pugh , Ryan Sweet , Steve Jacobson , Christian Hansson , Ross Jekel , Yongshao Ruan
IPC分类号： G06F9/44
CPC分类号： G06F11/36
摘要： Improved methods of software diagnostics are provided. Searches of data sources are conducted using search terms from internal computer information to obtain searched data. The searched data is processed by extracting technical features. The technical features are indexed to create indexes that can be searched via machine state. Filtering is conducted over the gathered data to create feeds that are available to customers.
摘要翻译：提供了改进的软件诊断方法。使用来自内部计算机信息的搜索术语来搜索数据源以获得搜索的数据。通过提取技术特征来处理搜索到的数据。索引技术特征来创建可以通过机器状态搜索的索引。对收集的数据进行过滤，以创建可供客户使用的Feed。

8. 发明授权

US06787326B1 Interaction between the VHL tumor suppressor and hypoxia inducible factor, and assay methods relating thereto 有权
标题翻译： VHL肿瘤抑制因子和缺氧诱导因子之间的相互作用以及与之相关的测定方法
公开(公告)号：US06787326B1
公开(公告)日：2004-09-07
申请号：US09959873
申请日：2001-11-09
申请人： Peter John Ratcliffe , Patrick Henry Maxwell , Christopher William Pugh
发明人： Peter John Ratcliffe , Patrick Henry Maxwell , Christopher William Pugh
IPC分类号： C12Q154
CPC分类号： C07K14/4703 , A61K38/00 , C07K14/4702 , C07K2319/00
摘要： The invention relates to the finding that the VHL tumour suppressor protein regulates hypoxia inducible factor &agr; subunits, by targeting HIF &agr; for destruction in normoxic, but not hypoxic cells. The invention provides assays for modulators of this interaction, and peptides based upon HIF &agr; subunit sequence which may modulate this interaction.
摘要翻译：本发明涉及VHL肿瘤抑制蛋白调节缺氧诱导因子α亚基的发现，其靶向HIFα以在正常氧而不是缺氧细胞中破坏。本发明提供了这种相互作用的调节剂的测定法，以及可以调节这种相互作用的基于HIFα亚基序列的肽。

9. 发明授权

US06630970B2 Polarizers for use with liquid crystal displays 失效
公开(公告)号：US06630970B2
公开(公告)日：2003-10-07
申请号：US09897318
申请日：2001-07-02
申请人： Giorgio Trapani , William K. Smyth , Philip Ralli , James Gordon , John Cael , John C. Branca , David M. Foresyth , Atsushi Suzuki , William Pugh
发明人： Giorgio Trapani , William K. Smyth , Philip Ralli , James Gordon , John Cael , John C. Branca , David M. Foresyth , Atsushi Suzuki , William Pugh
IPC分类号： G01F11336
CPC分类号： G02F1/133528
摘要： A liquid crystal display structure includes a liquid crystal display cell having a front surface and a back surface. One or more intrinsic polarizers lacking protective coatings thereon, such as K-type polarizers and thin KE polarizer sheets, are disposed adjacent to the front and back surfaces of the liquid crystal display cell. Alternatively, thinly cladded or encased iodine polarizers are disposed adjacent to the front and back surfaces of the liquid crystal display cell. The liquid crystal display structure may be used in conjunction with other optical display elements to enhance the brightness and contrast of the liquid crystal display.

10. 发明授权

US06074765A Grinding rod chemistry and method of heat treatment to enhance wearability 失效
标题翻译：研磨棒的化学和热处理方法提高耐磨性
公开(公告)号：US06074765A
公开(公告)日：2000-06-13
申请号：US89526
申请日：1998-06-03
申请人： Robert William Pugh
发明人： Robert William Pugh
IPC分类号： B02C17/20 , C21D1/64 , C21D9/00 , C22C38/04 , C22C38/22 , C21D9/08
CPC分类号： C21D1/64 , B02C17/20 , C21D9/0075 , C22C38/04 , C22C38/22 , C21D2211/008 , C21D2211/009 , C21D2221/01 , C21D2221/10 , Y10S148/902 , Y10T428/12458
摘要： A grinding rod chemistry enhances wearability and durability of a steel rod and comprises levels of carbon to achieve a surface hardness in excess of 55 Rockwell C and levels of chromium which achieve significant depth in the formed outer martensite shell. The grinding rod has a core greater than 99% pearlite with a hardness less than 45 Rockwell C and the end portions of the rod are soft and have a hardness less than 35 Rockwell C. The steel bar of the selected chemistry is treated by reheating to above its austenitising temperature, transferring with minimal cooling to an open tubular quench vessel while securing the bar in the vessel to minimize bar warping, introducing quench water into the inlet end of the vessel and passing the liquid through the vessel to ensure uniform heat removal. The outer martensite shell is tempered by allowing the bar to soak back after quenching. The bar end portions are reheated in a furnace to elevate the end portions above the austenitising temperature and air cooling each end portion to provide the engineered end portion hardness of less than 35 Rockwell C.
摘要翻译：研磨棒化学提高了钢棒的耐磨性和耐久性，并且包括达到表面硬度超过55的表面硬度的洛氏硬度C和在形成的外部马氏体壳中达到显着深度的铬的水平。研磨棒具有大于99％的硬度小于45的洛氏硬度的珠光体，并且棒的端部是柔软的，并且具有小于35的洛氏硬度C.所选择的化学物质的钢棒通过再加热高于其奥氏体化温度，将最小的冷却转移到开放式管状骤冷容器，同时将棒固定在容器中以最小化棒翘曲，将骤冷水引入容器的入口端并使液体通过容器以确保均匀的散热。外部马氏体壳通过使棒在淬火后浸泡回火来回火。棒端部在炉中再加热以将端部部分升高到奥氏体化温度以上，并且每个端部部分空气冷却，以提供小于35洛氏硬度C的工程化端部硬度。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式