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1. 发明申请

US20060201883A1 Polymer matrixes having nanoscale channels and uses 审中-公开
标题翻译：具有纳米尺度通道和用途的聚合物基体
公开(公告)号：US20060201883A1
公开(公告)日：2006-09-14
申请号：US10545875
申请日：2004-02-18
申请人： William Hofmeister , David Wright
发明人： William Hofmeister , David Wright
IPC分类号： B29C67/20 , B01D61/00
CPC分类号： B29C67/202 , B01D15/34 , B01D39/1676 , B01D2239/10 , B01J20/26 , B01J20/265 , B01J20/28026 , B01J20/28095 , B01L3/06 , B01L3/502707 , B01L3/502761 , B01L7/54 , B01L2200/12 , B01L2300/0819 , B01L2300/0877 , B01L2300/0896 , B01L2300/1827 , B01L2300/185 , B81C1/00071 , B81C2201/034 , B82Y15/00 , B82Y30/00 , Y10T436/255
摘要： Disclosed herein are polymer matrixes having nanoscale channels dispersed therein and to methods for preparing such matrixes. Also disclosed are uses of such polymer matrixes, such as for separating and analyzing materials. Still further, disclosed are devices that include such polymer matrixes.
摘要翻译：本文公开了具有分散在其中的纳米级通道的聚合物基质和用于制备这种基质的方法。还公开了这种聚合物基质的用途，例如用于分离和分析材料。更进一步地，公开了包括这种聚合物基质的装置。

2. 发明授权

US06994894B2 Method and system for thick-film deposition of ceramic materials 失效
公开(公告)号：US06994894B2
公开(公告)日：2006-02-07
申请号：US09958705
申请日：2001-04-20
申请人： William Hofmeister
发明人： William Hofmeister
IPC分类号： C23C14/30 , C23C14/28 , C23C8/00
CPC分类号： C23C14/30 , C04B35/4508 , C04B35/62665 , C04B2235/3215 , C04B2235/3224 , C04B2235/3225 , C04B2235/3281 , C04B2235/3282 , C23C4/12 , C23C4/123 , C23C24/04
摘要： A method of depositing a solid film on a substrate in which a stream comprising particles suspended in a transport gas is moved through a heating zone. The particles are combined with the transport gas from a powder feeder operatively coupled to a gas flow tube. The particle stream is directed toward the heating zone by ejecting the powder stream from a nozzle connected to a distal end of the gas flow tube. A radiation source is directed at the suspended particles as they move through the heating zone so that the particles heated to a molten state. The droplets are undercooled in a cooling zone before impact with the substrate.

3. 发明申请

US20060141607A1 Capillary perfused bioreactors with multiple chambers 有权
公开(公告)号：US20060141607A1
公开(公告)日：2006-06-29
申请号：US10525559
申请日：2003-08-27
申请人： John Wikswo , Franz Baudenbacher , Alex Prokop , Eugene Leboeuf , Chang Chung , David Cliffel , Frederick Haselton , William Hofmeister , Charles Lin , Lisa McCawley , Randall Reiserer , Mark Stremler
发明人： John Wikswo , Franz Baudenbacher , Alex Prokop , Eugene Leboeuf , Chang Chung , David Cliffel , Frederick Haselton , William Hofmeister , Charles Lin , Lisa McCawley , Randall Reiserer , Mark Stremler
IPC分类号： C12M1/34
CPC分类号： B01L3/502761 , B01L3/502746 , B01L2200/0668 , B01L2300/0816 , B01L2300/0864 , B01L2300/0877 , B01L2300/10 , B01L2400/0406 , B01L2400/0415 , B01L2400/0487 , C12M23/16 , C12M29/10
摘要： A bioreactor for cultivating living cells in a liquid medium. In one embodiment of the present invention, the bioreactor includes a first substrate having a first surface, an opposite second surface and edges. The bioreactor further includes a second substrate having a first surface and an opposite second surface, defining a cavity with a bottom surface, where the bottom surface is located therebetween the first surface and the second surface. The first surface of the first substrate is received by the second surface of the second substrate to cover the cavity so as to form a channel for receiving cells and a liquid medium. In forming the bioreactor, the channel is sized to allow the growth of a layer of cells on a biocompatible coating layer and a flow of liquid in the channel. The flow of liquid is controlled so as to provide a known shear force to the layer of cells. The flow of liquid can be further controlled so as to provide an environment that simulates a vascular space in the channel.

4. 发明授权

US06555180B2 System and method for direct fabrication of micro/macro scale objects in a vacuum using electromagnetic steering 失效
公开(公告)号：US06555180B2
公开(公告)日：2003-04-29
申请号：US10030490
申请日：2001-10-25
申请人： William Hofmeister , David Gustafson , Bridget Rogers
发明人： William Hofmeister , David Gustafson , Bridget Rogers
IPC分类号： B05D104
CPC分类号： C23C24/04 , B05B1/26 , B05B5/001 , B05B7/228 , C23C24/00
摘要： A system and method for directing metal or ceramic particles toward a substrate (18) in a vacuum chamber includes a powder hopper (11), an enclosure (12) containing multiple differentially pumped vacuum chambers (19), a charging lamp (13), a tube (14), multiple charging and heating diodes 15, and an electromagnetic field generating device (EFGD) (17). The hopper (11) holds metal or ceramic particles, the chambers (19) propel the particles through the tube (14) towards substrate (18) positioned close to the tube, charging lamp (13) charges the particles, diodes (15) are used to heat the particles, and the EFGD (17) controls the direction of the particles propelled out of the tube.

5. 发明申请

US20060154361A1 Bioreactors with substance injection capacity 有权
标题翻译：具有物质注入能力的生物反应器
公开(公告)号：US20060154361A1
公开(公告)日：2006-07-13
申请号：US10525648
申请日：2003-08-27
申请人： John Wikswo , Franz Baudenbacher , Frederick Haselton , William Hofmeister , Charles Lin , Lisa McCawley , Mark Stremler , Alissa Weaver
发明人： John Wikswo , Franz Baudenbacher , Frederick Haselton , William Hofmeister , Charles Lin , Lisa McCawley , Mark Stremler , Alissa Weaver
IPC分类号： C12M3/00 , C12M3/06
CPC分类号： B01L3/502761 , B01L3/502723 , B01L3/502746 , B01L2200/0668 , B01L2300/0645 , B01L2300/0681 , B01L2300/0816 , B01L2300/0887 , B01L2300/10 , B01L2400/0633 , B01L2400/086 , C12M23/16 , C12M25/14 , C12M29/04 , C12M29/10 , C12M35/08 , C12M41/46
摘要： A bioreactor with substance injection capability. In one embodiment, the bioreactor includes a first substrate having a first surface, an opposite second surface and edges. The bioreactor further includes a second substrate having a first surface and an opposite second surface, defining a cavity with a bottom surface, where the bottom surface is located therebetween the first surface and the second surface. The first surface of the first substrate is received by the second surface of the second substrate to cover the cavity so as to form a chamber for receiving cells and a liquid medium. A port is formed in the second substrate between the bottom surface and the first surface of the second substrate. As formed, the port is in fluid communication with the chamber to allow a stream of substance to be introduced into the chamber. The stream of substance is controlled so as to provide a gradient, or a concentration gradient of the substance, to the chamber. The stream of substance includes a substance affecting the growth of cells such as chemokine.
摘要翻译：具有物质注入能力的生物反应器。在一个实施例中，生物反应器包括具有第一表面，相对的第二表面和边缘的第一基底。生物反应器还包括具有第一表面和相对的第二表面的第二基底，其限定具有底表面的空腔，其中底表面位于第一表面和第二表面之间。第一基板的第一表面被第二基板的第二表面接收以覆盖空腔，以形成用于容纳电池和液体介质的室。在第二基板的第二基板的底表面和第一表面之间形成端口。如此形成的，端口与腔室流体连通，以允许物质流被引入腔室。物质流被控制以便向腔室提供物质的梯度或浓度梯度。物质流包括影响细胞生长的物质，如趋化因子。

6. 发明申请

US20050112049A1 Methods of direct growth of carbon nanotubes on catalytic surfaces 审中-公开
标题翻译：在催化表面上直接生长碳纳米管的方法
公开(公告)号：US20050112049A1
公开(公告)日：2005-05-26
申请号：US10495198
申请日：2002-12-18
申请人： William Hofmeister
发明人： William Hofmeister
IPC分类号： D01F9/127 , D01F9/12 , B05D3/00
CPC分类号： B82Y30/00 , D01F9/127
摘要： The present invention uses a conductor as a catalytic support for carbon nanotube growth. The use of conductive catalytic support will provide a contact to the nanotubes with low resistance. Carbon nanotubes grown on insulators must be modified to allow good connections. Second, creation of catalytic particles has been largely accomplished by precipitation of transition metals from salt solutions or thermal decomposition of thin films, while the present method uses precipitation from a solid solution. This will allow better control of the size distribution of catalysts. The precipitates will be coherent with the support allowing good anchoring of the catalysts for base growth of carbon nanotubes. Third, the approach is amenable to patterning by photolithography or other means of applying copper/transition metal thin films.
摘要翻译：本发明使用导体作为碳纳米管生长的催化载体。使用导电催化载体将提供与低电阻的纳米管的接触。生长在绝缘体上的碳纳米管必须进行修改，以实现良好的连接。第二，催化颗粒的产生主要通过从盐溶液中沉淀过渡金属或薄膜的热分解而实现，而本方法使用固溶体沉淀。这将有助于更好地控制催化剂的尺寸分布。沉淀物将与支持物一致，允许用于碳纳米管的基底生长的催化剂的良好锚定。第三，该方法适于通过光刻或其它施加铜/过渡金属薄膜的方法进行图案化。

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