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1. 发明申请

US20100015148A1 METHODS AND COMPOSITIONS FOR THE UTILIZATION AND TARGETING OF OSTEOMIMICRY 审中-公开
标题翻译：方法和组合物的使用和目标的OSTEOMIMICRY
公开(公告)号：US20100015148A1
公开(公告)日：2010-01-21
申请号：US12343063
申请日：2008-12-23
申请人： Leland W. K. Chung , Wen-Chin Huang , Valerie Odero-Marah , Daqing Wu , Chia-Ling Hsieh , Haiyen Zhau
发明人： Leland W. K. Chung , Wen-Chin Huang , Valerie Odero-Marah , Daqing Wu , Chia-Ling Hsieh , Haiyen Zhau
IPC分类号： A61K39/395 , C12N5/02 , A61K31/7088 , C12Q1/68
CPC分类号： G01N33/5011 , A61K31/7088 , A61K38/00 , A61K39/395 , A61K45/06 , A61K2039/505 , C07K16/2833 , C07K2317/73 , C12N15/113 , C12N2310/14 , C12Q1/6886
摘要： A method for interfering with osteomimetic properties of a cell includes introducing into the cell an osteomimecry-interfering compound, wherein said osteomimecry-interfering compound prevents or ameliorates the expression of the osteomimetic properties of said cell. A method for treating or ameliorating an osteotropic-related cancer or disorder in a subject includes administering to the subject an osteomimecry interfering compound. A method for identifying a compound that modulates the osteomimetic potential of a cell includes contacting a cell exhibiting osteomimetic potential with a test compound; measuring expression levels of one or more osteomimetic gene products in the cell in the presence and in the absence of the test compound; and identifying a compound that modulates the osteomimetic potential, wherein the compound changes the expression levels of one or more osteomimetic gene products in the cell.
摘要翻译：用于干扰细胞的骨模拟性质的方法包括向细胞中引入骨干哺乳干扰化合物，其中所述骨修复干扰化合物预防或改善所述细胞的骨模拟性质的表达。用于治疗或改善受试者中的骨相关性癌症或病症的方法包括向受试者施用骨前体干扰化合物。用于鉴定调节细胞的骨模拟潜力的化合物的方法包括使表现出骨骼发展潜力的细胞与测试化合物接触; 在存在和不存在测试化合物的情况下测量细胞中一种或多种骨模拟基因产物的表达水平; 以及鉴定调节所述骨模拟潜力的化合物，其中所述化合物改变所述细胞中一种或多种成骨细胞基因产物的表达水平。

2. 发明授权

US06257308B1 Strainer screen support frame 失效
标题翻译：过滤器屏幕支架
公开(公告)号：US06257308B1
公开(公告)日：2001-07-10
申请号：US09668630
申请日：2000-09-21
申请人： Wen-Chin Huang
发明人： Wen-Chin Huang
IPC分类号： A47H300
CPC分类号： F24F13/084
摘要： A strainer screen support frame has a main shelf, a blocking panel, and an upper pressing panel. The main shelf has an upper plate, a separation plate, a guide bevel plate, a blocking plate, a click recess, and a base seat. The upper plate has a first groove. The separation plate has a second groove and a downward bar. A slot is formed between the blocking plate and the base seat. The base seat has a third groove and a fourth groove. The blocking panel has a downward protruded block. The upper pressing panel has a connection edge, a downward panel, a first click groove, and a positioning groove. A screen frame is disposed between the separation plate and the blocking plate. The blocking panel is inserted in the slot.
摘要翻译：过滤器屏幕支撑框架具有主搁板，阻挡板和上压板。主架具有上板，分隔板，导向斜板，挡板，咔嗒凹槽和基座。上板具有第一槽。分离板具有第二凹槽和向下的杆。在阻挡板和基座之间形成有槽。基座具有第三凹槽和第四凹槽。阻挡板具有向下突出的块。上压板具有连接边缘，向下面板，第一点击槽和定位槽。筛分框架设置在分隔板和阻挡板之间。阻塞面板插入插槽中。

3. 发明申请

US20110142848A1 ANTI-BETA-2-MICROGLOBULIN AGENTS AND THE USE THEREOF 审中-公开
标题翻译：抗β-2-微粒蛋白剂及其用途
公开(公告)号：US20110142848A1
公开(公告)日：2011-06-16
申请号：US13056926
申请日：2009-08-07
申请人： Leland W.K. Chung , Sajni Josson , Wen-Chin Huang , Haiyen E. Zhau
发明人： Leland W.K. Chung , Sajni Josson , Wen-Chin Huang , Haiyen E. Zhau
IPC分类号： A61K39/395 , A61K31/7088 , A61K31/69 , A61K31/7068 , A61K33/24 , A61K31/704 , A61K31/337 , A61K31/7048 , A61K31/395 , A61P35/00 , A61M37/00
CPC分类号： C07K16/2833 , A61K31/7105 , A61K39/39558 , A61K45/06 , A61K2300/00
摘要： A method for treating cancer includes treating a subject with an agent against beta-2-microglobulin; and treating the subject with radiation or a cancer therapeutic agent. The agent against beta-2-microglobulin includes anti-b2-M antibodies and miRNAs.
摘要翻译：用于治疗癌症的方法包括用针对β-2-微球蛋白的药剂治疗受试者; 并用辐射或癌症治疗剂治疗受试者。针对β-2-微球蛋白的药物包括抗b2-M抗体和miRNA。

4. 发明授权

US07374434B1 Open terminal connector, method of fabrication of same 有权
标题翻译：开式端子连接器，其制造方法
公开(公告)号：US07374434B1
公开(公告)日：2008-05-20
申请号：US11826785
申请日：2007-07-18
申请人： Wen-Chin Huang
发明人： Wen-Chin Huang
IPC分类号： H01R12/00
CPC分类号： H01R13/621 , H01R13/6658
摘要： An open terminal connector formed of a plug-in connector, a circuit board, a terminal block, baffles, an electrically insulative inner housing and an electrically insulative outer housing, in which the baffles stop the molten material from entering wiring holes of the terminal block during molding of the inner housing and the outer housing and reinforce the structural strength of the connector after molding of the inner housing and the outer housing, and the outer housing is directly injection-molded on all parts to prohibit the internal metal conducting terminals and the circuit board from direct contact with the outside air, allowing the connector to be used under a high humidity and/or critical temperature environment.
摘要翻译：一种由插入式连接器，电路板，端子块，挡板，电绝缘内壳和电绝缘外壳构成的开式端子连接器，其中挡板阻止熔融材料进入端子块的接线孔在内壳和外壳的成型过程中，在内壳和外壳成型后，加强连接器的结构强度，外壳在所有部件上直接注塑成型，以防止内部金属导电端子和电路板与外部空气直接接触，允许连接器在高湿度和/或临界温度环境下使用。

5. 发明授权

US06838194B2 Efficient organic electroluminescent devices with red fluorescent dopants 有权
标题翻译：具有红色荧光掺杂剂的高效有机电致发光器件
公开(公告)号：US06838194B2
公开(公告)日：2005-01-04
申请号：US10348502
申请日：2003-01-20
申请人： Wen-Yao Huang , Min-Jong Chang , Wen-Chin Huang
发明人： Wen-Yao Huang , Min-Jong Chang , Wen-Chin Huang
IPC分类号： C09K11/06 , H01L51/00 , H01L51/30 , H01L51/50 , H05B33/14 , B32B9/00
CPC分类号： H05B33/14 , C09K11/06 , C09K2211/1033 , H01L51/0037 , H01L51/0059 , H01L51/006 , H01L51/0065 , H01L51/0067 , H01L51/0077 , H01L51/0078 , H01L51/0081 , H01L51/0092 , H01L51/5012 , H01L51/5048 , H01L51/5088 , H01L2251/308 , Y10S428/917
摘要： An organic electroluminescent (EL) device (10) in accordance with the present invention comprises, in sequence, a glass substrate (11), an anode layer (12), a hole-injecting layer (13), a hole-transporting layer (14), an luminescent layer (15), an electron-transporting layer (16), an electron-injecting layer (17) and a cathode layer (18). The luminescent layer (15) is doped with a guest fluorescent doping material, and the guest fluorescent doping material for the luminescent layer (15) comprises a compound represented by Formula I: wherein R1, R2, R3, R4, R5, and R6 each independently represents a linear or branched aliphatic group having from 1 to 10 carbon atoms or an aromatic group having from 5 to 20 carbon atoms.
摘要翻译：根据本发明的有机电致发光（EL）装置（10）依次包括玻璃基板（11），阳极层（12），空穴注入层（13），空穴传输层 14），发光层（15），电子传输层（16），电子注入层（17）和阴极层（18）。发光层（15）掺杂有客体荧光掺杂材料，并且用于发光层（15）的客体荧光掺杂材料包含由式I表示的化合物：其中R1，R2，R3，R4，R5和R6各自独立地表示具有1至10个碳原子的直链或支链脂族基团或具有5至20个碳原子的芳族基团。

6. 发明申请

US20130010501A1 BISYNCHRONOUS RESONANT SWITCHING-TYPE DIRECT CURRENT POWER SUPPLY 审中-公开
标题翻译：双相谐振开关型直流电源
公开(公告)号：US20130010501A1
公开(公告)日：2013-01-10
申请号：US13284651
申请日：2011-10-28
申请人： Wen-Chin Huang
发明人： Wen-Chin Huang
IPC分类号： H02M3/335
CPC分类号： H02M1/4225 , H02M3/33592 , H02M3/3387 , Y02B70/126 , Y02B70/1433 , Y02B70/1475 , Y02P80/112
摘要： A bisynchronous resonant switching-type direct current power supply includes a power supply unit, a power factor correcting unit, a resonant converting unit, and a synchronous rectifying unit. The power supply unit includes a power supply circuit to receive an alternating current signal, and a rectifying-and-filtering circuit operable to obtain a direct current voltage output from the alternating current signal. The power factor correcting unit includes a voltage booster, an active power factor correcting chip circuit and two transistor control circuits. The resonant converting unit includes a power switch circuit, a resonant chip circuit, and a voltage converting circuit. The voltage converting circuit has primary and secondary windings. The synchronous rectifying unit includes first and second resonant bridge rectifier circuits and a supply voltage output circuit.
摘要翻译：双同步谐振开关型直流电源包括电源单元，功率因数校正单元，谐振转换单元和同步整流单元。电源单元包括用于接收交流信号的电源电路以及可操作以获得从交流信号输出的直流电压的整流和滤波电路。功率因数校正单元包括升压器，有源功率因数校正芯片电路和两个晶体管控制电路。谐振转换单元包括电源开关电路，谐振芯片电路和电压转换电路。电压转换电路具有初级和次级绕组。同步整流单元包括第一和第二谐振桥式整流器电路和电源电压输出电路。

7. 发明授权

US07611383B1 RJ45 connector device having key structure for changing pin definitions 有权
标题翻译： RJ45连接器设备具有用于更改引脚定义的键结构
公开(公告)号：US07611383B1
公开(公告)日：2009-11-03
申请号：US12318072
申请日：2008-12-22
申请人： Wen Chin Huang
发明人： Wen Chin Huang
IPC分类号： H01R13/66
CPC分类号： H01R13/6658 , H01R13/6461 , H01R13/7175 , H01R24/64 , H01R29/00
摘要： An RJ45 connector device having a key structure for changing pin definitions is provided. The RJ45 connector device includes a conversion processor, a key, an information processor, and output pins. When the key is pressed to trigger a conversion signal, the conversion processor first converts a part of input information into relay information. Then, according to the conversion signal, the information processor converts the input information and the relay information into output information through designated processing and then output the output information through the output pins, so as to solve the problem that various connector devices occupy a lot of the available space of an electronic device when being used, thereby saving the available space of the electronic device and enabling a single connector device to achieve technical effects of a multi-functional connector device in terms of switching pin definitions.
摘要翻译：提供具有用于改变销定义的键结构的RJ45连接器装置。 RJ45连接器设备包括转换处理器，钥匙，信息处理器和输出引脚。当按下键来触发转换信号时，转换处理器首先将输入信息的一部分转换为中继信息。然后，根据转换信号，信息处理器通过指定处理将输入信息和继电器信息转换为输出信息，然后通过输出引脚输出输出信息，以解决各种连接器装置占用大量电子设备的可用空间，从而节省电子设备的可用空间，并且使得单个连接器设备能够在切换引脚定义方面实现多功能连接器设备的技术效果。

8. 发明授权

US06649089B2 Red organic electroluminescent materials 有权
标题翻译：红色有机电致发光材料
公开(公告)号：US06649089B2
公开(公告)日：2003-11-18
申请号：US10348405
申请日：2003-01-20
申请人： Min-Jong Chang , Wen-Yao Huang , Wen-Chin Huang
发明人： Min-Jong Chang , Wen-Yao Huang , Wen-Chin Huang
IPC分类号： C09K1106
CPC分类号： C07D471/04 , Y10S428/917
摘要： A red fluorescent material comprising a compound of Formula I: wherein R1, R2, R3, R4, R5, and R6 each independently represents a linear or branched aliphatic group having from 1 to 10 carbon atoms or an aromatic group having from 5 to 20 carbon atoms.
摘要翻译：包含式I化合物的红色荧光材料：其中R 1，R 2，R 3，R 4，R 5和R 6各自独立地表示具有1至10个碳原子的直链或支链脂族基团或具有5至20个碳原子的芳族基团原子

9. 发明申请

US20070078085A1 Methods and compositions for the utilization and targeting of osteomimicry 审中-公开
标题翻译：用于骨肉瘤的方法和组合物
公开(公告)号：US20070078085A1
公开(公告)日：2007-04-05
申请号：US11248337
申请日：2005-10-13
申请人： Leland Chung , Wen-Chin Huang , Valerie Odero-Marah , Daqing Wu , Chia-Ling Hsieh , Haiyen Zhau
发明人： Leland Chung , Wen-Chin Huang , Valerie Odero-Marah , Daqing Wu , Chia-Ling Hsieh , Haiyen Zhau
IPC分类号： A61K48/00 , A61K38/18 , C12Q1/68 , G01N33/574
CPC分类号： A61K31/70 , A61K48/00 , C07K16/22 , C07K16/2833 , C07K2317/76 , C12N15/113 , C12N2310/14 , C12Q1/6886 , G01N33/5011
摘要： The present invention relates to compositions and methods for modulating osteomimicry within tumor and tissue cells with calcification potential. The invention further relates to screening compounds that modulate osteomimicry within tumor and tissue cells with calcification potential. Methods for using compounds identified by the screening assays for therapeutic treatments also are provided. The invention further relates to methods of treating those tumors and other diseases and disorders with calcification potential with compounds that modulate their osteomimetic potential.
摘要翻译：本发明涉及在具有钙化潜能的肿瘤和组织细胞内调节骨肉瘤的组合物和方法。本发明进一步涉及筛选在具有钙化潜能的肿瘤和组织细胞内调节骨肉瘤的化合物。还提供了通过筛选测定法鉴定的化合物用于治疗性治疗的方法。本发明还涉及用调节其骨骼模拟潜能的化合物治疗具有钙化潜能的那些肿瘤和其它疾病和病症的方法。

10. 发明申请

US20100253036A1 Wheeled Vehicle that is Operated by Stepping Upward and Downward 审中-公开
标题翻译：通过向上和向下逐步操作的轮式车辆
公开(公告)号：US20100253036A1
公开(公告)日：2010-10-07
申请号：US12419489
申请日：2009-04-07
申请人： Ping-Sheng Liu , Wen-Chin Huang
发明人： Ping-Sheng Liu , Wen-Chin Huang
IPC分类号： B62K3/10
CPC分类号： B62M1/24 , B62K3/10 , B62M1/20 , B62M1/26
摘要： A wheeled vehicle includes a main frame, a drive axle rotatably mounted on the main frame, a chainwheel secured on the drive axle, an eccentric shaft secured on the drive axle, a support post mounted on the main frame, a rocking arm pivotally mounted on the support post, and a linking member having an upper end pivotally connected with the rocking arm to move with the rocking arm and a lower end pivotally connected with the eccentric shaft to move the eccentric shaft. The rocking arm has two opposite sides each provided with a pedal. Thus, the wheeled vehicle is driven to move forward by stepping the pedals of the rocking arm upward and downward in a reciprocal manner to provide a different pedalling manner.
摘要翻译：轮式车辆包括主框架，可旋转地安装在主框架上的驱动轴，固定在驱动轴上的链轮，固定在驱动轴上的偏心轴，安装在主框架上的支撑柱，枢转地安装在所述支撑柱和连接构件具有与所述摇臂枢转地连接的上端，所述上端与所述摇臂一起移动，所述下端与所述偏心轴枢转连接以移动所述偏心轴。摇臂具有两个相对的侧面，每侧设有踏板。因此，通过以相互的方式向上和向下移动摇臂的踏板来驱动轮式车辆向前移动，以提供不同的踏板方式。

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