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1. 发明申请

US20100168422A1 METHODS AND INTERMEDIATES USEFUL IN THE SYNTHESIS OF HEXAHYDROFURO [2,3-B]FURAN-3-OL 审中-公开
标题翻译：合成十六氢呋喃[2,3-B] FURAN-3-OL的方法和中间体
公开(公告)号：US20100168422A1
公开(公告)日：2010-07-01
申请号：US12345838
申请日：2008-12-30
申请人： Weiping Chen
发明人： Weiping Chen
IPC分类号： C07D413/14 , C07D493/04 , C07D307/32 , C07D265/30 , C07C291/04 , C07D417/14 , C07F9/655
CPC分类号： C07D295/088 , C07C239/12 , C07D307/33 , C07D493/04 , C07F9/4006 , C07F9/6561
摘要： Provided herein are compounds and methods useful for preparing hexahydrofuro[2,3-b]furan-3-ol. Hexahydrofuro[2,3-b]furan-3-ol can be efficiently synthesized in four steps from readily available starting materials.
摘要翻译：本文提供了可用于制备六氢呋喃并[2,3-b]呋喃-3-醇的化合物和方法。六氢呋喃并[2,3-b]呋喃-3-醇可以从容易获得的起始原料四步高效地合成。

2. 发明申请

US20100160660A1 BIS(FERROCENYLPHOSPHINO) FERROCENE LIGANDS USED IN ASSYMETRIC HYDROGENATION REACTIONS 失效
标题翻译： BIS（FERROCENYLPHOSPHINO）在大气加氢反应中使用的FERROCENE配体
公开(公告)号：US20100160660A1
公开(公告)日：2010-06-24
申请号：US12449638
申请日：2008-02-15
申请人： Weiping Chen , Felix Spindler , Ulrike Nettekoven , Benoît Pugin
发明人： Weiping Chen , Felix Spindler , Ulrike Nettekoven , Benoît Pugin
IPC分类号： C07C51/36 , C07F19/00 , C07C231/12
CPC分类号： C07C51/36 , B01J2231/645 , B01J2531/16 , B01J2531/17 , B01J2531/18 , B01J2531/821 , B01J2531/822 , B01J2531/824 , B01J2531/827 , B01J2531/828 , B01J2531/842 , B01J2531/845 , B01J2531/847 , C07F17/02 , C07C59/64 , C07C59/68 , C07C57/30
摘要： Abstract Compounds of the formula (I) in the form of racemates, enantiomerically pure diastereomers or a mixture of diastereomers, where the radicals R1 are identical or different and are each C1-C4-alkyl; m is 0 or an integer from 1 to 4; n is 0 or an integer from 1 to 3; p is 0 or an integer from 1 to 5; R2 is an aromatic hydrocarbon radical or a C-bonded heterohydrocarbon radical and R3 is an aliphatic or C-bonded heteroaliphatic hydrocarbon radical; R2 and R3 are identical or different and are each an aliphatic or C-bonded heteroaliphatic hydrocarbon radical; R4 is an unsubstituted or C1-C6-alkyl-, C1-C6-alkoxy- or halogen-substituted hydrocarbon radical; and A is a secondary amino group, are ligands for metal complexes which are suitable as catalysts for homogeneous enantioselective hydrogenation.
摘要翻译：摘要式（I）化合物为外消旋体，对映体纯的非对映体或非对映异构体的混合物，其中基团R 1相同或不同并且各自为C 1 -C 4 - 烷基; m为0或1〜4的整数; n为0或1〜3的整数; p为0或1至5的整数; R2是芳族烃基或C键合的杂烃基，R3是脂族或C键合的杂脂族烃基; R2和R3相同或不同，各自为脂族或C键合的杂脂族烃基; R4是未取代的或C1-C6-烷基 - ，C1-C6-烷氧基或卤素取代的烃基; 并且A是仲氨基，是金属络合物的配体，其适合作为均相对映选择性氢化的催化剂。

3. 发明申请

US20090124812A1 Ferrocenediphosphines 有权
标题翻译：二茂铁
公开(公告)号：US20090124812A1
公开(公告)日：2009-05-14
申请号：US12226213
申请日：2007-04-11
申请人： Weiping Chen , Felix Spindler , Benoit Pugin
发明人： Weiping Chen , Felix Spindler , Benoit Pugin
IPC分类号： C07F15/02
CPC分类号： C07F17/02 , C07B53/00 , C07F9/52
摘要： Compounds of the formula I in the form of enantiomerically pure diastereomers or a mixture of diastereomers, (I), where the radicals R1 are identical or different and are each C1-C4-alkyl; m is 0 or an integer from 1 to 3; n is 0 or an integer from 1 to 4; R2 is a hydrocarbon radical or a C-bonded heterohydrocarbon radical; Cp is unsubstituted or C1-C4-alkyl-substituted cyclopentadienyl; Y is a C-bonded chiral group which directs metals of metallation reagents into the ortho position; and Phos is a P-bonded P(III) substituent. The compounds are chiral ligands for complexes of transition metals which are used as homogeneous catalysts in asymmetric syntheses.
摘要翻译：式I化合物为对映体纯的非对映体形式或非对映异构体（I）的混合物，其中基团R 1相同或不同并且各自为C 1 -C 4 - 烷基; m为0或1〜3的整数; n为0或1至4的整数; R2是烃基或C键合的杂烃基; Cp是未取代的或C 1 -C 4烷基取代的环戊二烯基; Y是将金属化试剂的金属引导到邻位的C-键合手性基团; Phos是P键合的P（III）取代基。这些化合物是用于不对称合成中的均相催化剂的过渡金属络合物的手性配体。

4. 发明申请

US20110241345A1 EXPANDABLE MULTI-SET CIRCULATION HYDROELECTRIC POWER GENERATION METHOD AND SYSTEM 审中-公开
标题翻译：可扩展多循环水力发电方法与系统
公开(公告)号：US20110241345A1
公开(公告)日：2011-10-06
申请号：US13061707
申请日：2008-09-09
申请人： Weiping Chen
发明人： Weiping Chen
IPC分类号： H02K7/18 , F03B17/04
CPC分类号： E02B9/00 , F03B17/005 , F05B2240/40 , Y02E10/22
摘要： An expandable multi-set circulation hydroelectric power generation method and system. The system includes a power station control area (A), a transformer substation area (B), a circulation cistern (C) provided with a plurality of small cisterns (CA1 to CA20). Gates (E1 to E20) and protection screenings are installed in the small cisterns (CA1 to CA20). A water pump set station area is provided with a plurality of water pump sets (D1 to D20). The water pump sets (D1 to D20) are connected to the small cisterns (CA1 to CA20). The small cisterns (CA1 to CA20) are connected to pressure pipes (G1 to G20). The pressure pipes (G1 to G20) are connected to work done pipes (H1 to H10). A plurality of water turbine generator sets (F1 to F51) and a plurality of gates (E42, E43, E47, E50, E53, E56, E59, E63, E64, E65) are installed in the work done pipes (H1 to H10).
摘要翻译：一种可扩展的多集循环水电发电方法及系统。该系统包括电站控制区域（A），变电站区域（B），设有多个小水箱（CA1至CA20）的循环水箱（C）。门（E1至E20）和保护屏蔽安装在小水箱（CA1至CA20）中。水泵设置站区域设置有多个水泵组（D1〜D20）。水泵组（D1〜D20）与小水箱（CA1〜CA20）连接。小水箱（CA1至CA20）连接到压力管（G1至G20）。压力管道（G1至G20）连接工作管道（H1至H10）。在工作完成的管道（H1至H10）中安装有多个水轮发电机组（F1至F51）和多个门（E42，E43，E47，E50，E53，E56，E59，E63，E64，E65）。

5. 发明申请

US20090270499A1 Process for Synthesizing Atazanavir 审中-公开
标题翻译：合成阿扎那韦的方法
公开(公告)号：US20090270499A1
公开(公告)日：2009-10-29
申请号：US12109249
申请日：2008-04-24
申请人： Weiping Chen
发明人： Weiping Chen
IPC分类号： A61K31/336 , C07D213/55 , C07D301/02 , C07C211/00 , A61P31/18 , C07C269/00 , C07D303/02 , A61K31/27
CPC分类号： C07C209/62 , C07C271/22 , C07D213/53 , C07D213/56 , C07C211/27
摘要： This invention relates to a process for synthesizing Atazanvir, including novel intermediates and novel steps to various intermediates along the synthetic pathway.
摘要翻译：本发明涉及一种合成阿扎那韦的方法，包括新型中间体和沿合成途径向不同中间体的新步骤。

6. 发明授权

US08106227B2 Ferrocenediphosphines 有权
标题翻译：二茂铁
公开(公告)号：US08106227B2
公开(公告)日：2012-01-31
申请号：US12226213
申请日：2007-04-11
申请人： Weiping Chen , Felix Spindler , Benoît Pugin
发明人： Weiping Chen , Felix Spindler , Benoît Pugin
IPC分类号： C07F15/02
CPC分类号： C07F17/02 , C07B53/00 , C07F9/52
摘要： Compounds of the formula I in the form of enantiomerically pure diastereomers or a mixture of diastereomers, (I), where the radicals R1 are identical or different and are each C1-C4-alkyl; m is 0 or an integer from 1 to 3; n is 0 or an integer from 1 to 4; R2 is a hydrocarbon radical or a C-bonded heterohydrocarbon radical; Cp is unsubstituted or C1-C4-alkyl-substituted cyclopentadienyl; Y is a C-bonded chiral group which directs metals of metallation reagents into the ortho position; and Phos is a P-bonded P(III) substituent. The compounds are chiral ligands for complexes of transition metals which are used as homogeneous catalysts in asymmetric syntheses.
摘要翻译：式I化合物为对映体纯的非对映体形式或非对映异构体（I）的混合物，其中基团R 1相同或不同并且各自为C 1 -C 4 - 烷基; m为0或1〜3的整数; n为0或1至4的整数; R2是烃基或C键合的杂烃基; Cp是未取代的或C 1 -C 4烷基取代的环戊二烯基; Y是将金属化试剂的金属引导到邻位的C-键合手性基团; Phos是P键合的P（III）取代基。这些化合物是用于不对称合成中的均相催化剂的过渡金属络合物的手性配体。

7. 发明授权

US07977499B2 Bis(ferrocenylphosphino) ferrocene ligands used in asymmetric hydrogenation reactions 失效
标题翻译：用于不对称氢化反应的双（二茂铁基膦基）二茂铁配体
公开(公告)号：US07977499B2
公开(公告)日：2011-07-12
申请号：US12449638
申请日：2008-02-15
申请人： Weiping Chen , Felix Spiindler , Ulrike Nettekoven , Benoît Pugin
发明人： Weiping Chen , Felix Spiindler , Ulrike Nettekoven , Benoît Pugin
IPC分类号： C07F15/00 , C07C57/30
CPC分类号： C07C51/36 , B01J2231/645 , B01J2531/16 , B01J2531/17 , B01J2531/18 , B01J2531/821 , B01J2531/822 , B01J2531/824 , B01J2531/827 , B01J2531/828 , B01J2531/842 , B01J2531/845 , B01J2531/847 , C07F17/02 , C07C59/64 , C07C59/68 , C07C57/30
摘要： Abstract Compounds of the formula (I) in the form of racemates, enantiomerically pure diastereomers or a mixture of diastereomers, where the radicals R1 are identical or different and are each C1-C4-alkyl; m is 0 or an integer from 1 to 4; n is 0 or an integer from 1 to 3; p is 0 or an integer from 1 to 5; R2 is an aromatic hydrocarbon radical or a C-bonded heterohydrocarbon radical and R3 is an aliphatic or C-bonded heteroaliphatic hydrocarbon radical; R2 and R3 are identical or different and are each an aliphatic or C-bonded heteroaliphatic hydrocarbon radical; R4 is an unsubstituted or C1-C6-alkyl-, C1-C6-alkoxy- or halogen-substituted hydrocarbon radical; and A is a secondary amino group, are ligands for metal complexes which are suitable as catalysts for homogeneous enantioselective hydrogenation.
摘要翻译：摘要式（I）化合物为外消旋体，对映体纯的非对映体或非对映异构体的混合物，其中基团R 1相同或不同并且各自为C 1 -C 4 - 烷基; m为0或1〜4的整数; n为0或1〜3的整数; p为0或1至5的整数; R2是芳族烃基或C键合的杂烃基，R3是脂族或C键合的杂脂族烃基; R2和R3相同或不同，各自为脂族或C键合的杂脂族烃基; R4是未取代的或C1-C6-烷基 - ，C1-C6-烷氧基或卤素取代的烃基; 并且A是仲氨基，是金属络合物的配体，其适合作为均相对映选择性氢化的催化剂。

8. 发明授权

US07369343B1 Disk drive correcting track address during a write operation 有权
标题翻译：磁盘驱动器在写入操作期间校正磁道地址
公开(公告)号：US07369343B1
公开(公告)日：2008-05-06
申请号：US11494242
申请日：2006-07-27
申请人： Teik E E Yeo , Weiping Chen Jiang
发明人： Teik E E Yeo , Weiping Chen Jiang
IPC分类号： G11B15/04 , G11B5/09
CPC分类号： G11B19/041 , G11B5/09 , G11B5/596 , G11B27/3027 , G11B2220/2516
摘要： A disk drive is disclosed comprising a head actuated over a disk having a plurality of servo tracks, wherein each servo track comprises a plurality of servo sectors and each servo sector comprises a track address. A read signal from the head representing a first track address in one of the servo sectors is processed in order to generate a detected track address which is compared to a first target track address to obtain a first track address error. A correction metric is generated representing a likelihood that the first track address error was caused by a detection error, and if the correction metric exceeds a threshold, the detected track address is corrected in response to the first track address error, and the write operation is continued. If the correction metric does not exceed the threshold, the write operation is aborted.
摘要翻译：公开了一种磁盘驱动器，其包括在具有多个伺服磁道的盘上致动的磁头，其中每个伺服磁道包括多个伺服扇区，并且每个伺服扇区包括磁道地址。处理来自表示伺服扇区之一中的第一轨道地址的磁头的读取信号，以便产生与第一目标磁道地址相比较以获得第一磁道地址错误的检测磁道地址。生成表示第一轨道地址误差由检测误差引起的可能性的校正度量，并且如果校正度量超过阈值，则响应于第一轨道地址错误校正检测到的轨道地址，并且写入操作是继续。如果校正度量值不超过阈值，写入操作将中止。

9. 发明申请

US20060135355A1 Nitrogen-containing ligands 审中-公开
标题翻译：含氮配体
公开(公告)号：US20060135355A1
公开(公告)日：2006-06-22
申请号：US10524550
申请日：2003-07-30
申请人： William Hems , Weiping Chen , Jianliang Xiao
发明人： William Hems , Weiping Chen , Jianliang Xiao
IPC分类号： B01J31/00
CPC分类号： C07C247/10 , B01J31/1616 , B01J31/1625 , B01J31/165 , B01J31/1658 , B01J31/1683 , B01J31/1805 , B01J2231/32 , B01J2231/326 , B01J2231/4211 , B01J2231/4261 , B01J2231/48 , B01J2231/50 , B01J2231/641 , B01J2231/643 , B01J2231/72 , B01J2231/74 , B01J2531/821 , B01J2531/824 , B01J2531/828 , C07B2200/07 , C07B2200/11 , C07C29/145 , C07C211/27 , C07C211/29 , C07C217/60 , C07C217/64 , C07C33/46
摘要： An immobilised nitrogen-containing ligand is described comprising the reaction product of a compound of formula (I) wherein R5, R6, R7 and R8 are independently hydrogen, a saturated or unsaturated C1-C10 alkyl group, an aryl group, a urethane group, a sulphonyl group or form an imine group, R1, R2, R3, and R4 are independently hydrogen, a saturated or unsaturated C1-C10 alkyl group or an aryl group and at least one of R1, R2, R3 and R4 is functionalised with a functional group, and a solid support having a site capable of reacting with said functional group. The nitrogen-containing ligand is useful for preparing immobilised catalysts for performing e.g. asymmetric catalysis.
摘要翻译：描述了一种固定化含氮配体，其包括式（I）化合物的反应产物，其中R 5，R 6，R 7，R 7， R 8独立地是氢，饱和或不饱和的C 1 -C 10烷基，芳基，氨基甲酸酯基，磺酰基或亚胺基，R 1， R 2，R 3和R 4独立地是氢，饱和或不饱和的C 1 -C 10烷基或芳基，并且在 R 1，R 2，R 3和R 4中的至少一个用官能团官能化，并且具有能够与所述官能团反应的位置的固体支持体。含氮配体可用于制备固定催化剂，用于进行例如不对称催化。

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