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1. 发明申请

US20120149656A1 WATER SOLUTION OF 20(R) - GINSENOSIDE Rg3 PHARMACEUTICAL COMPOSITION AND PROCESS THEREOF 有权
标题翻译： 20（R） - GINSENOSIDE Rg3药物组合物的水溶液及其制备方法
公开(公告)号：US20120149656A1
公开(公告)日：2012-06-14
申请号：US12301996
申请日：2007-05-18
申请人： Li Fu , Hong Liu , Mingming Lu , Qi Lu , Seong Tae Cho , Wanzhe Cui
发明人： Li Fu , Hong Liu , Mingming Lu , Qi Lu , Seong Tae Cho , Wanzhe Cui
IPC分类号： A61K31/704 , A61P25/00 , A61P37/04 , A61P29/00 , C07J17/00 , A61P35/00
CPC分类号： A61K31/704 , A61K9/0019 , A61K9/08 , A61K9/19 , A61K47/40 , A61K47/6951 , B82Y5/00 , Y02P20/582
摘要： A preparation of a kind of 20(R)-ginsenoside Rg3 medicinal composition aqueous solution containing ginsenoside Rg3 0.5˜10 mg/ml: add 0.1-5% of ginsenoside solution to 0.1˜30% of adjuvant A, B{circle around (1)}{circle around (2)}{circle around (5)} at the temperature of 40˜100° C., the ratio of these two is 1:1˜300, add water after the solvent is recycled under reduced pressure; another kind of 20(R)-ginsenoside Rg3 medicinal composition aqueous solution contains 0.1˜2 mg/ml of 20 (R) of the ginsenoside Rg3, the preparation: add 0.1˜5% of ginsenoside solution to 20˜65% of adjuvant B{circle around (3)}{circle around (4)} at the temperature of 60˜100° C., main material to adjuvant B=1:100˜400, add water after the solvent is recycled under reduced pressure. The above 20 (R) ginsenoside Rg3 composition aqueous solution and the powder after lyophilizaton can be used to prepare injectable, oral administration and external use, and the bioactivity of these preparations is high, and with the actions of anti cancer, efficacy potentiation and toxicity attenuation effects of the combined chemical or radiation therapy of tumor, enhancement of human immune functions, improvement of human memory, anti fatigue, and detumescence, pain relieving.
摘要翻译：含有人参皂甙Rg3的20（R） - 人参皂苷Rg3药物组合物水溶液0.5〜10mg / ml的制剂：将0.1〜30％的人参皂甙溶液加入0.1〜30％的佐剂A，B ）} {圆周（2）} {圆周（5）}在40〜100℃的温度下，这两者的比例为1：1〜300，在减压下回收溶剂后加水; 另外一种20（R） - 人参皂甙Rg3药用组合物水溶液含有0.1〜2mg / ml的人参皂甙Rg3，其制备方法：将20〜65％的人参皂甙溶液加入0.1〜5％ {圆周围（3）} {圆周围（4）}，温度为60〜100℃，辅料B = 1：100〜400的主要原料，在减压下回收溶剂后加水。上述20（R）人参皂苷Rg3组合物水溶液和冻干后的粉末可用于制备注射，口服和外用，并且这些制剂的生物活性高，并具有抗癌作用，功效增强和毒性肿瘤组合化学或放射治疗的衰减效应，人体免疫功能的增强，人体记忆的改善，抗疲劳和消肿，疼痛缓解。

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