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1. 发明授权

US08378059B2 Supramolecular handcuffs in polymeric architecture 有权
标题翻译：超分子手铐在聚合物结构
公开(公告)号：US08378059B2
公开(公告)日：2013-02-19
申请号：US12734925
申请日：2008-12-04
申请人： Urs Rauwald , Oren Alexander Scherman
发明人： Urs Rauwald , Oren Alexander Scherman
IPC分类号： A61K31/787 , C08G73/00 , C08G79/00
CPC分类号： C08G83/008 , A61K47/58 , A61K47/60 , A61K47/61 , C08G85/00
摘要： This invention pertains generally to supramolecular polymers comprising a polymeric molecule linked to a first CB[8] guest molecule and an attachment compound linked to a second CB[8] guest molecule, wherein the first and second CB[8] guest molecules form a ternary host-guest complex with a CB[8] molecule which non-covalently links the polymeric molecule and the attachment compound in a supramolecular polymer. These polymers are useful as vehicles for delivery of a therapeutic compound for use in a method of treatment of the human or animal body, in particular for use in a method of delivering the therapeutic compound to a target site in an individual. The invention also provides methods for the preparation of the supramolecular polymers.
摘要翻译：本发明通常涉及包含与第一CB [8]客体分子连接的聚合物分子和连接到第二CB [8]客体分子的连接化合物的超分子聚合物，其中第一和第二CB [8]客体分子形成三元具有与超分子聚合物非共价连接聚合物分子和连接化合物的CB [8]分子的宿主 - 复合物。这些聚合物可用作递送用于治疗人或动物体的方法的治疗化合物的载体，特别是用于将治疗化合物递送至个体的靶位点的方法。本发明还提供了制备超分子聚合物的方法。

2. 发明申请

US20100247477A1 SUPRAMOLECULAR HANDCUFFS IN POLYMERIC ARCHITECTURE 有权
标题翻译：聚合物结构中的分子量分析
公开(公告)号：US20100247477A1
公开(公告)日：2010-09-30
申请号：US12734925
申请日：2008-12-04
申请人： Urs Rauwald , Oren Alexander Scherman
发明人： Urs Rauwald , Oren Alexander Scherman
IPC分类号： A61K31/787 , C08G73/00 , C08G79/00
CPC分类号： C08G83/008 , A61K47/58 , A61K47/60 , A61K47/61 , C08G85/00
摘要： This invention pertains generally to supramolecular polymers comprising a polymeric molecule linked to a first CB[8] guest molecule and an attachment compound linked to a second CB[8] guest molecule, wherein the first and second CB[8] guest molecules form a ternary host-guest complex with a CB[8] molecule which non-covalently links the polymeric molecule and the attachment compound in a supramolecular polymer. These polymers are useful as vehicles for delivery of a therapeutic compound for use in a method of treatment of the human or animal body, in particular for use in a method of delivering the therapeutic compound to a target site in an individual. The invention also provides methods for the preparation of the supramolecular polymers.
摘要翻译：本发明通常涉及包含与第一CB [8]客体分子连接的聚合物分子和连接到第二CB [8]客体分子的连接化合物的超分子聚合物，其中第一和第二CB [8]客体分子形成三元具有与超分子聚合物非共价连接聚合物分子和连接化合物的CB [8]分子的宿主 - 复合物。这些聚合物可用作递送用于治疗人或动物体的方法的治疗化合物的载体，特别是用于将治疗化合物递送至个体的靶位点的方法。本发明还提供了制备超分子聚合物的方法。

3. 发明授权

US08540959B2 Bulk cutting of carbon nanotubes using electron beam irradiation 失效
标题翻译：使用电子束照射大量切割碳纳米管
公开(公告)号：US08540959B2
公开(公告)日：2013-09-24
申请号：US12299634
申请日：2007-05-07
申请人： Kirk J. Ziegler , Urs Rauwald , Robert H. Hauge , Howard K. Schmidt , W. Carter Kittrell , Zhenning Gu , Irene Morin Marek
发明人： Kirk J. Ziegler , Urs Rauwald , Robert H. Hauge , Howard K. Schmidt , Richard E. Smalley , W. Carter Kittrell , Zhenning Gu
IPC分类号： D01F9/12
CPC分类号： C01B32/176 , C01B32/174 , C01B2202/02 , C01B2202/28 , C01B2202/34
摘要： According to some embodiments, the present invention provides a method for attaining short carbon nanotubes utilizing electron beam irradiation, for example, of a carbon nanotube sample. The sample may be pretreated, for example by oxonation. The pretreatment may introduce defects to the sidewalls of the nanotubes. The method is shown to produces nanotubes with a distribution of lengths, with the majority of lengths shorter than 100 tun. Further, the median length of the nanotubes is between about 20 nm and about 100 nm.
摘要翻译：根据一些实施方案，本发明提供了利用电子束照射来获得例如碳纳米管样品的短碳纳米管的方法。样品可以进行预处理，例如通过氧化。预处理可能在纳米管的侧壁上引入缺陷。该方法显示产生具有长度分布的纳米管，其大部分长度短于100μm。此外，纳米管的中值长度在约20nm和约100nm之间。

4. 发明申请

US20100284898A1 BULK CUTTING OF CARBON NANOTUBES USING ELECTRON BEAM IRRADIATION 失效
标题翻译：使用电子束辐照的碳纳米管的切割
公开(公告)号：US20100284898A1
公开(公告)日：2010-11-11
申请号：US12299634
申请日：2007-05-07
申请人： Kirk J. Ziegler , Urs Rauwald , Robert H. Hauge , Howard K. Schmidt , Irene Morin Marek , Zhenning Gu , W. Carter Kittrell
发明人： Kirk J. Ziegler , Urs Rauwald , Robert H. Hauge , Howard K. Schmidt , Irene Morin Marek , Zhenning Gu , W. Carter Kittrell
IPC分类号： D01F9/12
CPC分类号： C01B32/176 , C01B32/174 , C01B2202/02 , C01B2202/28 , C01B2202/34
摘要： According to some embodiments, the present invention provides a method for attaining short carbon nanotubes utilizing electron beam irradiation, for example, of a carbon nanotube sample. The sample may be pretreated, for example by oxonation. The pretreatment may introduce defects to the sidewalls of the nanotubes. The method is shown to produces nanotubes with a distribution of lengths, with the majority of lengths shorter than 100 tun. Further, the median length of the nanotubes is between about 20 nm and about 100 nm.
摘要翻译：根据一些实施方案，本发明提供了利用电子束照射来获得例如碳纳米管样品的短碳纳米管的方法。样品可以进行预处理，例如通过氧化。预处理可能在纳米管的侧壁上引入缺陷。该方法显示产生具有长度分布的纳米管，其大部分长度短于100μm。此外，纳米管的中值长度在约20nm和约100nm之间。

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