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1. 发明授权

US5008166A Method for manufacturing a color filter 失效
标题翻译：彩色滤光片的制造方法
公开(公告)号：US5008166A
公开(公告)日：1991-04-16
申请号：US434570
申请日：1989-11-08
申请人： Toshihiro Aoki
发明人： Toshihiro Aoki
IPC分类号： G02B5/20 , G02F1/1335 , G03F7/00 , H01L31/0216
CPC分类号： H01L31/02162 , G02F1/133516 , G03F7/0007
摘要： A method of manufacturing color filters in which a photosensitive film, which is used for forming filter elements, is formed on a substrate. A photomask with a given stripe pattern is placed above the photoresistive film. Under this condition, the photomasked-film is subjected to a first exposure process. The photomask is then moved in the direction of the stripes in the mask pattern. Following a second exposure process, developing, dyeing and dyeing-preventing processes are performed for color filter element formation. The foregoing steps are performed for each filter element for a specified color.
摘要翻译：一种制造滤色器的方法，其中在基片上形成用于形成滤光元件的感光膜。具有给定条纹图案的光掩模放置在光刻胶膜上。在该条件下，对光掩模膜进行第一曝光处理。然后将光掩模沿掩模图案中的条纹的方向移动。在第二曝光过程之后，进行用于滤色器元件形成的显影，染色和染色防止过程。对于指定颜色的每个滤光元件执行上述步骤。

2. 发明授权

US08569378B2 p27 protein inducer 有权
标题翻译： p27蛋白诱导物
公开(公告)号：US08569378B2
公开(公告)日：2013-10-29
申请号：US12669944
申请日：2008-07-18
申请人： Toshiyuki Sakai , Hitoshi Iikura , Ikumi Hyoudoh , Toshihiro Aoki , Noriyuki Furuichi , Masayuki Matsushita , Fumio Watanabe , Sawako Ozawa , Masahiro Sakaitani , Pil-Su Ho , Yasushi Tomii , Kenji Takanashi , Naoki Harada
发明人： Toshiyuki Sakai , Hitoshi Iikura , Ikumi Hyoudoh , Toshihiro Aoki , Noriyuki Furuichi , Masayuki Matsushita , Fumio Watanabe , Sawako Ozawa , Masahiro Sakaitani , Pil-Su Ho , Yasushi Tomii , Kenji Takanashi , Naoki Harada
IPC分类号： A01N41/02 , A01N41/06 , A01N43/16 , A61K31/16 , A61K31/18 , A61K31/35 , C07D311/00 , C07C331/00 , C07C381/00 , C07C303/00 , C07C309/00 , C07C311/00
CPC分类号： C07D405/14 , C07D407/04 , C07D409/04 , C07D409/12 , C07D413/12 , C07D417/04 , C07D417/12 , C07D417/14 , C07D491/052
摘要： The present invention provides a p27 protein inducing agent comprising a compound represented by general formula (11) below or pharmaceutically acceptable salt thereof as an active ingredient: wherein G1, G2, G3 and G8 are each independently selected from —N═ etc., Ring G6 is selected from divalent aryl etc., A is selected from amino etc., G4 is selected from oxygen etc., G5 is selected from oxygen etc., G7 is selected from —CH2— etc., and R2 is selected from C1-6 alkyl etc.
摘要翻译：本发明提供了包含下述通式（11）表示的化合物或其药学上可接受的盐作为活性成分的p27蛋白诱导剂：其中，G1，G2，G3和G8各自独立地选自-N =等，环 G6选自二价芳基等，A选自氨基等，G4选自氧等，G5选自氧等，G7选自-CH2-等，R2选自C1- 6烷基等

3. 发明申请

US20110092700A1 Novel Coumarin Derivative Having Antitumor Activity 有权
标题翻译：具有抗肿瘤活性的新型香豆素衍生物
公开(公告)号：US20110092700A1
公开(公告)日：2011-04-21
申请号：US12960134
申请日：2010-12-03
申请人： Hitoshi Iikura , Ikumi Hyoudoh , Toshihiro Aoki , Noriyuki Furuichi , Masayuki Matsushita , Fumio Watanabe , Sawako Ozawa , Masahiro Sakaitani , Pil-Su Ho , Yasushi Tomii , Kenji Takanashi , Naoki Harada
发明人： Hitoshi Iikura , Ikumi Hyoudoh , Toshihiro Aoki , Noriyuki Furuichi , Masayuki Matsushita , Fumio Watanabe , Sawako Ozawa , Masahiro Sakaitani , Pil-Su Ho , Yasushi Tomii , Kenji Takanashi , Naoki Harada
IPC分类号： C07D265/26 , C07D311/16 , C07D409/06 , C07D403/12 , C07D491/14 , C07D417/12 , C07D401/10 , C07D403/10 , C07D403/14 , C07D413/12
CPC分类号： C07D311/18 , C07D405/12 , C07D417/12
摘要： The present invention provides a compound represented by general formula (1) below or a pharmaceutically acceptable salt thereof: wherein: X is selected from heteroaryl etc., Y1 and Y2 are selected from —N═ etc., Y3 and Y4 are selected from —CH═ etc., A is selected from sulfamide etc., R1 is selected from hydrogen etc., and R2 is selected from C1-6 alkyl etc. The compound or salt has sufficiently high antitumor activity, and is useful in the treatment of cell proliferative disorders, particularly cancers. The present invention also provides a pharmaceutical composition containing the compound or salt as an active ingredient.
摘要翻译：本发明提供下述通式（1）表示的化合物或其药学上可接受的盐：其中：X选自杂芳基等，Y1和Y2选自-N =等，Y 3和Y 4选自 - CH等等，A选自磺酰胺等，R1选自氢等，R2选自C1-6烷基等。化合物或盐具有足够高的抗肿瘤活性，可用于细胞的治疗增殖性疾病，特别是癌症。本发明还提供含有作为活性成分的化合物或盐的药物组合物。

4. 发明授权

US08278465B2 Coumarin derivative having antitumor activity 有权
标题翻译：具有抗肿瘤活性的香豆素衍生物
公开(公告)号：US08278465B2
公开(公告)日：2012-10-02
申请号：US12960134
申请日：2010-12-03
申请人： Hitoshi Iikura , Ikumi Hyoudoh , Toshihiro Aoki , Noriyuki Furuichi , Masayuki Matsushita , Fumio Watanabe , Sawako Ozawa , Masahiro Sakaitani , Pil-Su Ho , Yasushi Tomii , Kenji Takanashi , Naoki Harada
发明人： Hitoshi Iikura , Ikumi Hyoudoh , Toshihiro Aoki , Noriyuki Furuichi , Masayuki Matsushita , Fumio Watanabe , Sawako Ozawa , Masahiro Sakaitani , Pil-Su Ho , Yasushi Tomii , Kenji Takanashi , Naoki Harada
IPC分类号： C07D311/00
CPC分类号： C07D311/18 , C07D405/12 , C07D417/12
摘要： The present invention provides a compound represented by general formula (1) below or a pharmaceutically acceptable salt thereof: wherein: X is selected from heteroaryl etc., Y1 and Y2 are selected from —N═ etc., Y3 and Y4 are selected from —CH═ etc., A is selected from sulfamide etc., R1 is selected from hydrogen etc., and R2 is selected from C1-6 alkyl etc. The compound or salt has sufficiently high antitumor activity, and is useful in the treatment of cell proliferative disorders, particularly cancers. The present invention also provides a pharmaceutical composition containing the compound or salt as an active ingredient.
摘要翻译：本发明提供下述通式（1）表示的化合物或其药学上可接受的盐：其中：X选自杂芳基等，Y1和Y2选自-N =等，Y 3和Y 4选自 - CH等等，A选自磺酰胺等，R1选自氢等，R2选自C1-6烷基等。该化合物或盐具有足够高的抗肿瘤活性，可用于细胞的治疗增殖性疾病，特别是癌症。本发明还提供含有作为活性成分的化合物或盐的药物组合物。

5. 发明申请

US20110009398A1 p27 Protein Inducer 有权
标题翻译： p27蛋白诱导剂
公开(公告)号：US20110009398A1
公开(公告)日：2011-01-13
申请号：US12669944
申请日：2008-07-18
申请人： Toshiyuki Sakai , Hitoshi Iikura , Ikumi Hyoudoh , Toshihiro Aoki , Noriyuki Furuichi , Masayuki Matsushita , Fumio Watanabe , Sawako Ozawa , Masahiro Sakaitani , Pil-Su Ho , Yasushi Tomii , Kenji Takanashi , Naoki Harada
发明人： Toshiyuki Sakai , Hitoshi Iikura , Ikumi Hyoudoh , Toshihiro Aoki , Noriyuki Furuichi , Masayuki Matsushita , Fumio Watanabe , Sawako Ozawa , Masahiro Sakaitani , Pil-Su Ho , Yasushi Tomii , Kenji Takanashi , Naoki Harada
IPC分类号： A61K31/536 , A61K31/4965 , A61K31/506 , A61K31/436 , A61K31/427 , A61K31/366 , C07D413/02 , C07D405/02 , C07D405/14 , C07D471/02 , C07D417/12 , C07D311/06 , C07D417/14
CPC分类号： C07D405/14 , C07D407/04 , C07D409/04 , C07D409/12 , C07D413/12 , C07D417/04 , C07D417/12 , C07D417/14 , C07D491/052
摘要： The present invention provides a p27 protein inducing agent comprising a compound represented by general formula (11) below or pharmaceutically acceptable salt thereof as an active ingredient: wherein G1, G2, G3 and G8 are each independently selected from —N═ etc., Ring G6 is selected from divalent aryl etc., A is selected from amino etc., G4 is selected from oxygen etc., G5 is selected from oxygen etc., G7 is selected from —CH2— etc., and R2 is selected from C1-6 alkyl etc.
摘要翻译：本发明提供一种p27蛋白诱导剂，其含有下述通式（11）表示的化合物或其药学上可接受的盐作为活性成分：其中，G1，G2，G3和G8各自独立地选自-N等。环 G6选自二价芳基等，A选自氨基等，G4选自氧等，G5选自氧等，G7选自-CH2-等，R2选自C1- 6烷基等

6. 发明申请

US20100004233A1 NOVEL COUMARIN DERIVATIVE HAVING ANTITUMOR ACTIVITY 有权
标题翻译：具有抗肿瘤活性的新型香豆素衍生物
公开(公告)号：US20100004233A1
公开(公告)日：2010-01-07
申请号：US12161256
申请日：2007-02-09
申请人： Hitoshi Iikura , Ikumi Hyoudoh , Toshihiro Aoki , Noriyuki Furuichi , Masayuki Matsushita , Fumio Watanabe , Sawako Ozawa , Masahiro Sakaitani , Pil-Su Ho , Yasushi Tomii , Kenji Takanashi , Naoki Harada
发明人： Hitoshi Iikura , Ikumi Hyoudoh , Toshihiro Aoki , Noriyuki Furuichi , Masayuki Matsushita , Fumio Watanabe , Sawako Ozawa , Masahiro Sakaitani , Pil-Su Ho , Yasushi Tomii , Kenji Takanashi , Naoki Harada
IPC分类号： A61K31/536 , C07D311/06 , A61K31/352 , C07D405/12 , A61K31/506 , C07D413/12
CPC分类号： C07D311/18 , C07D405/12 , C07D417/12
摘要： The present invention provides a compound represented by general formula (1) below or a pharmaceutically acceptable salt thereof: wherein: X is selected from heteroaryl etc., Y1 and Y2 are selected from —N═ etc., Y3 and Y4 are selected from —CH═ etc., A is selected from sulfamide etc., R1 is selected from hydrogen etc., and R2 is selected from C1-6 alkyl etc. The compound or salt has sufficiently high antitumor activity, and is useful in the treatment of cell proliferative disorders, particularly cancers. The present invention also provides a pharmaceutical composition containing the compound or salt as an active ingredient.
摘要翻译：本发明提供下述通式（1）表示的化合物或其药学上可接受的盐：其中：X选自杂芳基等，Y1和Y2选自-N-等，Y3和Y4选自 - CH-等，A选自磺酰胺等，R1选自氢等，R2选自C1-6烷基等。化合物或盐具有足够高的抗肿瘤活性，可用于治疗细胞增殖性疾病，特别是癌症。本发明还提供含有作为活性成分的化合物或盐的药物组合物。

7. 发明授权

US07639322B2 Liquid crystal display device and method for manufacturing the same 失效
标题翻译：液晶显示装置及其制造方法
公开(公告)号：US07639322B2
公开(公告)日：2009-12-29
申请号：US12010046
申请日：2008-01-18
申请人： Dong-soo Son , Seo-hee Ha , Sung-ku Kang , Jong-su Lee , Toshihiro Aoki , Jai-sang Jung
发明人： Dong-soo Son , Seo-hee Ha , Sung-ku Kang , Jong-su Lee , Toshihiro Aoki , Jai-sang Jung
IPC分类号： G02F1/1335 , G02F1/1339
CPC分类号： G02F1/13394 , G02F1/133512 , G02F1/133514
摘要： A liquid crystal display device includes a first substrate having a plurality of first electrodes, a second substrate facing the first substrate and having a plurality of second electrodes perpendicular to the first electrodes to define sub-pixels at intersection regions between the first and second electrodes, a liquid crystal layer between the first and second substrates, a plurality of color filters between the first and second substrates adapted to correspond to respective sub-pixels, the color filters including first color filters and second color filters having a different shape than the first color filters, a black matrix between the color filters, the black matrix including vertical portions, horizontal portions, and step portions, each of the step portions corresponding to a respective second color filter, and a plurality of patterned spacers between the first and second substrates, each of the patterned spacers overlaps with a respective step-portion of the black matrix.
摘要翻译：液晶显示装置包括具有多个第一电极的第一基板，与第一基板相对的第二基板，具有与第一电极垂直的多个第二电极，以在第一和第二电极之间的交叉区域限定子像素，在所述第一和第二基板之间的液晶层，在所述第一和第二基板之间适于对应于各个子像素的多个滤色器，所述滤色器包括具有与所述第一颜色不同的形状的第一滤色器和第二滤色器滤色器，滤色器之间的黑矩阵，黑矩阵包括垂直部分，水平部分和台阶部分，每个阶梯部分对应于相应的第二滤色器，以及在第一和第二基板之间的多个图案化间隔物，每个图案化间隔物与黑矩阵的相应台阶部分重叠。

8. 发明授权

US5126868A Color compensated double layered liquid crystal display device 失效
标题翻译：彩色双层双层液晶显示装置
公开(公告)号：US5126868A
公开(公告)日：1992-06-30
申请号：US455946
申请日：1989-12-22
申请人： Seiichi Kizaki , Toshiomi Ono , Ken Kozima , Mikiya Itakura , Toshihiro Aoki
发明人： Seiichi Kizaki , Toshiomi Ono , Ken Kozima , Mikiya Itakura , Toshihiro Aoki
IPC分类号： G02F1/133 , G02F1/13363 , G02F1/1347 , G02F1/139
CPC分类号： G02F1/133636 , G02F1/13471 , G02F1/133382 , G02F1/1397
摘要： A display cell is mounted on a color-compensating cell. The display cell has a pair of substrates each having an alignment-treated surface, a first liquid-crystal layer and electrodes. Multiplex drive signals are supplied to the electrodes. The color-compensating cell has a second liquid-crystal layer. The molecules of the first liquid-crystal layer are twisted by a twist angle ranging from 160.degree. to 270.degree.. The molecules of the second liquid-crystal layer are twisted by the same angle in the opposite direction. The substrates are alignment-treated in two directions, respectively, which are substantially at right angles to each other. One of the polarizing plates has an optical axis crossing at 35.degree. to 50.degree. with an aligning direction of the liquid crystal molecules on that substrate adjacent to the polarizing plate, and crossing with the optical axis of the other polarizing plate at right angles. The second liquid-crystal cell compensates for the coloring of the light passing through the display cell. The second liquid-crystal layer has retardation .DELTA.n.sub.2 .multidot.d.sub.2, which is less than the retardation .DELTA.n.sub.1 .multidot.d.sub.1 of said first liquid-crystal layer, for compensating for a decrease in the retardation .DELTA.n.sub.1 .multidot.d.sub.1, which has resulted from the excitation of the liquid-crystal molecules by application of a bias voltage to unselected pixels of the display cell.

9. 发明授权

US4427816A .beta.-Diketone and hydrotalcite stabilizer compositions for halogen-containing polymers and polymer compositions containing the same 失效
标题翻译：含卤聚合物的β-二酮和水滑石稳定剂组合物及含有它们的聚合物组合物
公开(公告)号：US4427816A
公开(公告)日：1984-01-24
申请号：US344100
申请日：1982-01-29
申请人： Toshihiro Aoki , Yoshio Iida
发明人： Toshihiro Aoki , Yoshio Iida
IPC分类号： C08L27/00 , C08K3/22 , C08K3/24 , C08K3/26 , C08K3/28 , C08K5/07 , C08L1/00 , C08L27/06 , C08K3/30
CPC分类号： C08K3/26 , C08K5/07
摘要： Stabilizer compositions for halogen-containing polymers are provided composed of a .beta.-diketone as well as metal and organotin enolate salts thereof; and a hydrotalcite having the general formula:Mg.sub.1-x Al.sub.x (OH).sub.2 A.sub.x/2.mH.sub.2 Owhereinx is a number from 0 to 0.5;A is CO.sub.3.sup.= or SO.sub.4.sup.=, andm is a number representing the number of H.sub.2 O in the molecule.The stabilizer compositions are effective in enhancing the resistance to deterioration by heat and light of halogen-containing polymers and especially polyvinyl halide resins. The .beta.-diketone and hydrotalcite in these compositions exhibit a synergistic stabilizing effectiveness superior to either alone in like amount.
摘要翻译：提供含卤聚合物的稳定剂组合物由β-二酮及其金属和有机锡烯醇盐组成; 和具有以下通式的水滑石：Mg1-xAlx（OH）2Ax / 2.mH2O其中x为0至0.5的数; A是CO 3 =或SO 4 =，m是表示分子中H 2 O的数目的数。稳定剂组合物通过含卤聚合物，特别是聚卤乙烯树脂，能够有效地提高耐热和耐光劣化性。这些组合物中的β-二酮和水滑石表现出优于单独类似量的协同稳定效果。

10. 发明授权

US07897792B2 Coumarin derivative having antitumor activity 有权
标题翻译：具有抗肿瘤活性的香豆素衍生物
公开(公告)号：US07897792B2
公开(公告)日：2011-03-01
申请号：US12161256
申请日：2007-02-09
申请人： Hitoshi Iikura , Ikumi Hyoudoh , Toshihiro Aoki , Noriyuki Furuichi , Masayuki Matsushita , Fumio Watanabe , Sawako Ozawa , Masahiro Sakaitani , Pil-Su Ho , Yasushi Tomii , Kenji Takanashi , Naoki Harada
发明人： Hitoshi Iikura , Ikumi Hyoudoh , Toshihiro Aoki , Noriyuki Furuichi , Masayuki Matsushita , Fumio Watanabe , Sawako Ozawa , Masahiro Sakaitani , Pil-Su Ho , Yasushi Tomii , Kenji Takanashi , Naoki Harada
IPC分类号： C07D311/00
CPC分类号： C07D311/18 , C07D405/12 , C07D417/12
摘要： The present invention provides a compound represented by general formula (1) below or a pharmaceutically acceptable salt thereof: wherein: X is selected from heteroaryl etc., Y1 and Y2 are selected from —N═ etc., Y3 and Y4 are selected from —CH═ etc., A is selected from sulfamide etc., R1 is selected from hydrogen etc., and R2 is selected from C1-6 alkyl etc. The compound or salt has sufficiently high antitumor activity, and is useful in the treatment of cell proliferative disorders, particularly cancers. The present invention also provides a pharmaceutical composition containing the compound or salt as an active ingredient.
摘要翻译：本发明提供下述通式（1）表示的化合物或其药学上可接受的盐：其中：X选自杂芳基等，Y1和Y2选自-N =等，Y 3和Y 4选自 - CH等等，A选自磺酰胺等，R1选自氢等，R2选自C1-6烷基等。该化合物或盐具有足够高的抗肿瘤活性，可用于细胞的治疗增殖性疾病，特别是癌症。本发明还提供含有作为活性成分的化合物或盐的药物组合物。

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