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1. 发明申请

US20090082341A1 4-hydroxy-4-methyl-piperidine-1-carboxylic acid (4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide FOR THE TREATMENT OF POST-TRAUMATIC STRESS DISORDER 审中-公开
标题翻译： 4-羟基-4-甲基 - 哌啶-1-羧酸（4-甲氧基-7-吗啉-4-基 - 苯并噻唑-2-基） - 酰胺，用于治疗后交感应激障碍
公开(公告)号：US20090082341A1
公开(公告)日：2009-03-26
申请号：US12178509
申请日：2008-07-23
申请人： Tom Woiwode , Mark Moran
发明人： Tom Woiwode , Mark Moran
IPC分类号： A61K31/5377 , A61K31/551 , A61P25/22
CPC分类号： A61K31/445
摘要： Provided are methods of treating post-traumatic stress disorder with 4-hydroxy-4-methyl-piperidine-1-carboxylic acid (4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide. Also provided are methods of improving resilience with 4-hydroxy-4-methyl-piperidine-1-carboxylic acid (4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide. Also provided are methods of diagnosing post-traumatic stress disorder in a patient.
摘要翻译：提供了用4-羟基-4-甲基 - 哌啶-1-甲酸（4-甲氧基-7-吗啉-4-基 - 苯并噻唑-2-基） - 酰胺治疗创伤后应激障碍的方法。还提供了用4-羟基-4-甲基 - 哌啶-1-羧酸（4-甲氧基-7-吗啉-4-基 - 苯并噻唑-2-基） - 酰胺改善弹性的方法。还提供了诊断患者创伤后应激障碍的方法。

2. 发明申请

US20090054414A1 Rufinamide for the Treatment of Post-Traumatic Stress Disorder 审中-公开
标题翻译： Rufinamide治疗创伤后应激障碍
公开(公告)号：US20090054414A1
公开(公告)日：2009-02-26
申请号：US12178502
申请日：2008-07-23
申请人： Tom Woiwode , Mark Moran
发明人： Tom Woiwode , Mark Moran
IPC分类号： A61K31/5513 , A61K31/4196
CPC分类号： A61K31/4192 , A61K45/06 , A61K2300/00
摘要： Provided are methods of treating post-traumatic stress disorder with rufinamide. Also provided are methods of treating kindling and improving resilience with rufinamide. Also provided are methods of diagnosing post-traumatic stress disorder in a patient by administering to the patient a therapeutically effective amount of rufinamide and assessing at least one of sign, symptom, or symptom cluster of post-traumatic stress disorder; and diagnosing post-traumatic stress disorder in the patient if the rufinamide reduces at least one of sign, symptom, and symptom cluster of post-traumatic stress disorder.
摘要翻译：提供了用rufinamide治疗创伤后应激障碍的方法。还提供了使用rufinamide处理点燃和提高弹性的方法。还提供了通过向患者施用治疗有效量的rufinamide并评估创伤后应激障碍的征兆，症状或症状簇中的至少一种来诊断患者中创伤后应激障碍的方法; 并且如果rufinamide减少创伤后应激障碍的征兆，症状和症状簇中的至少一个，则诊断患者的创伤后应激障碍。

3. 发明申请

US20090054403A1 Treatment of Post-Traumatic Stress Disorder 审中-公开
标题翻译：治疗创伤后应激障碍
公开(公告)号：US20090054403A1
公开(公告)日：2009-02-26
申请号：US12178513
申请日：2008-07-23
申请人： Tom Woiwode , Mark Moran
发明人： Tom Woiwode , Mark Moran
IPC分类号： A61K31/55 , A61K31/4164 , A61K31/4525
CPC分类号： A61K31/535 , A61K31/4164 , A61K45/06 , A61K2300/00
摘要： Provided are methods of treating a patient diagnosed with post-traumatic stress disorder, by administering to the patient a therapeutically effective amount of Compound A. Also provided are methods of improving resilience in a patient by administering a therapeutically effective amount of Compound A. Also provided are methods of diagnosing post-traumatic stress disorder in a patient by administering to the patient a therapeutically effective amount of Compound A and assessing at least one of sign, symptom, or symptom cluster of post-traumatic stress disorder; and diagnosing post-traumatic stress disorder in the patient if the Compound A reduces at least one of sign, symptom, and symptom cluster of post-traumatic stress disorder.
摘要翻译：提供了通过向患者施用治疗有效量的化合物A来治疗诊断为创伤后应激障碍的患者的方法。还提供了通过施用治疗有效量的化合物A来改善患者的恢复力的方法。还提供了是通过向患者施用治疗有效量的化合物A并评估创伤后应激障碍的征兆，症状或症状簇中的至少一种来诊断患者中创伤后应激障碍的方法; 并且如果化合物A减少创伤后应激障碍的征兆，症状和症状簇中的至少一个，则诊断患者的创伤后应激障碍。

4. 发明申请

US20090041800A1 Methods for Treating Dependence 审中-公开
标题翻译：治疗依赖的方法
公开(公告)号：US20090041800A1
公开(公告)日：2009-02-12
申请号：US12187166
申请日：2008-08-06
申请人： Tom Woiwode , Mark Moran , Lesley Pickford
发明人： Tom Woiwode , Mark Moran , Lesley Pickford
IPC分类号： A61K36/06 , A61K31/4164 , A61K31/5513 , A61K31/4439 , A61P25/30 , A61K36/81 , A61K31/439
CPC分类号： A61K31/4164 , A61K9/08 , A61K31/415 , A61K31/417 , A61K45/06
摘要： Provided are methods of treating patients suffering from or susceptible to at least one symptom of abuse of, dependence on, or withdrawal from at least one substance with Compound A. Also provided are methods of treating at least one phase of substance dependence on at least one substance in patients and certain methods of treating at least one phase of cocaine dependence in patients.
摘要翻译：提供的是治疗患有或易受至少一种与化合物A的至少一种物质的滥用，依赖或从其中排出的症状的患者的方法。还提供了将至少一种物质依赖性至少一种治疗至少一种治疗的方法患者中的物质和某些治疗至少一个阶段可卡因依赖的方法。

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