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1. 发明申请

US20110122365A1 Eye Surgery System and Methods of Preparing and Performing an Eye Surgery 有权
标题翻译：眼科手术系统及准备与执行眼科手术
公开(公告)号：US20110122365A1
公开(公告)日：2011-05-26
申请号：US13055233
申请日：2009-07-24
申请人： Martin Kraus , Christoph Kuebler , Delbert Peter Andrews , Mark Lansu , Thomas Schuhrke , Anja Seiwert
发明人： Martin Kraus , Christoph Kuebler , Delbert Peter Andrews , Mark Lansu , Thomas Schuhrke , Anja Seiwert
IPC分类号： A61B3/13 , A61B3/14
CPC分类号： A61B3/14 , A61B3/13
摘要： A method for carrying out eye surgery comprises a comparison of images recorded before surgery with images recorded during surgery in order to generate a marker which represents a target orientation of an intraocular lens or a difference between a current orientation and the target orientation of the intraocular lens. An eye surgery system respectively comprises an imaging system which is used during a surgery and has a camera, and a diagnostic system which is used before surgery and which also has a camera. The imaging system used during surgery comprises an image processing device in order to perform a computation based on the recorded images, and in order to determine a respective orientation value, from which a representation of a marker representing the target orientation of the intraocular lens is obtained.
摘要翻译：用于进行眼睛手术的方法包括将手术前记录的图像与在手术期间记录的图像进行比较，以便产生表示眼内透镜的目标取向的标记或者目前取向与眼内透镜的目标取向之间的差异。眼科手术系统分别包括在手术期间使用并具有照相机的成像系统和在手术之前使用并且还具有照相机的诊断系统。在手术中使用的成像系统包括图像处理装置，以便基于所记录的图像执行计算，并且为了确定相应的取向值，从中获得表示眼内透镜的目标取向的标记的表示。

2. 发明申请

US20100041999A1 Process for quantitative display of blood flow 审中-公开
标题翻译：定量显示血流量的过程
公开(公告)号：US20100041999A1
公开(公告)日：2010-02-18
申请号：US12462037
申请日：2009-07-28
申请人： Thomas Schuhrke , Guenter Meckes , Joachim Steffen , Hans-Joachim Miesner , Frank Rudolph , Werner Nahm
发明人： Thomas Schuhrke , Guenter Meckes , Joachim Steffen , Hans-Joachim Miesner , Frank Rudolph , Werner Nahm
IPC分类号： A61B6/00 , G06K9/00
CPC分类号： A61B5/0261 , A61B5/0275 , G06T7/20 , G06T11/001 , G06T2207/30104
摘要： A method for the quantitative representation of the blood flow in a tissue or vascular region based on the signal of a contrast agent injected into the blood. In the process, several individual images of the signal emitted by the tissue or vascular region are recorded at successive points in time and are stored. For image areas of stored individual images the respective point in time is determined at which the signal has exceeded a certain threshold value and this point in time is represented for each of the image areas.
摘要翻译：基于注射到血液中的造影剂的信号定量表示组织或血管区域中的血流的方法。在该过程中，在连续的时间点记录由组织或血管区域发射的信号的几个单独图像并被存储。对于存储的各个图像的图像区域，确定相应的时间点，信号已经超过了某个阈值，并且针对每个图像区域表示了该时间点。

3. 发明授权

US06944354B2 Reflected or transmitted light scanner and image processing method for scanned-in image samples 失效
标题翻译：用于扫描图像样本的反射或透射光扫描器和图像处理方法
公开(公告)号：US06944354B2
公开(公告)日：2005-09-13
申请号：US09920252
申请日：2001-08-01
申请人： Thomas Groschup , Thomas Schuhrke
发明人： Thomas Groschup , Thomas Schuhrke
IPC分类号： H04N1/409 , H04N1/58 , G06K9/40
CPC分类号： H04N1/58 , H04N1/4097
摘要： A reflected or transmitted light scanner includes an illumination device for illuminating image material, a carrier for holding the image material, and a recording device for recording the light transmitted through the image material and for pixel by pixel conversion of the light into electric signals that can be used to generate original image signals in several colors as well as a defect signal. The reflected or transmitted light scanner further comprises a memory device for storing the image and defect signals, pixel by pixel; a computing device for generating low-pass signals from the image signals; a memory device for storing the low-pass signals, pixel by pixel; and a correction device for selecting between the image signal and the low-pass signal, or a combination of image signal and low-pass signal, for each pixel, in dependence upon the value or the position of the defect signal for the respective pixel.
摘要翻译：反射或透射光扫描器包括用于照射图像材料的照明装置，用于保持图像材料的载体，以及用于记录透过图像材料的光的记录装置，并且将光的像素转换成电信号，该电信号可以用于生成几种颜色的原始图像信号以及缺陷信号。反射或透射光扫描器还包括用于逐个存储图像和缺陷信号的存储器件; 用于从图像信号产生低通信号的计算装置; 用于逐个存储低通信号的存储器件; 以及用于根据每个像素的缺陷信号的值或位置，针对每个像素在图像信号和低通信号之间选择图像信号和低通信号的组合的校正装置。

4. 发明授权

US08708488B2 Eye surgery system and methods of preparing and performing an eye surgery 有权
标题翻译：眼科手术系统和准备和进行眼科手术的方法
公开(公告)号：US08708488B2
公开(公告)日：2014-04-29
申请号：US13055233
申请日：2009-07-24
申请人： Martin Kraus , Christoph Kuebler , Delbert Peter Andrews , Mark Lansu , Thomas Schuhrke , Anja Seiwert
发明人： Martin Kraus , Christoph Kuebler , Delbert Peter Andrews , Mark Lansu , Thomas Schuhrke , Anja Seiwert
IPC分类号： A61B3/14 , A61B3/00
CPC分类号： A61B3/14 , A61B3/13
摘要： A method for carrying out eye surgery comprises a comparison of images recorded before surgery with images recorded during surgery in order to generate a marker which represents a target orientation of an intraocular lens or a difference between a current orientation and the target orientation of the intraocular lens. An eye surgery system respectively comprises an imaging system which is used during a surgery and has a camera, and a diagnostic system which is used before surgery and which also has a camera. The imaging system used during surgery comprises an image processing device in order to perform a computation based on the recorded images, and in order to determine a respective orientation value, from which a representation of a marker representing the target orientation of the intraocular lens is obtained.
摘要翻译：用于进行眼睛手术的方法包括将手术前记录的图像与在手术期间记录的图像进行比较，以便产生表示眼内透镜的目标取向的标记或者目前取向与眼内透镜的目标取向之间的差异。眼科手术系统分别包括在手术期间使用并具有照相机的成像系统和在手术之前使用并且还具有照相机的诊断系统。在手术中使用的成像系统包括图像处理装置，以便基于所记录的图像执行计算，并且为了确定相应的取向值，从中获得表示眼内透镜的目标取向的标记的表示。

5. 发明授权

US07215821B2 Image processing method for automated contrast modification of digital image data 失效
标题翻译：用于数字图像数据自动对比度修改的图像处理方法
公开(公告)号：US07215821B2
公开(公告)日：2007-05-08
申请号：US10668716
申请日：2003-09-23
申请人： Thomas Schuhrke , Martin Rother
发明人： Thomas Schuhrke , Martin Rother
IPC分类号： G06K9/40 , G09G5/00 , H04N9/64
CPC分类号： H04N1/4092 , H04N1/4072
摘要： The invention relates to an image-processing method for automated contrast modification of digital image data. At least one low and one high-frequency signal are formed based on the digital image signal of the image data; the low-frequency signal component is modified using a characteristic-curve function; and then the modified, low-frequency signal is again added to the high-frequency signal component. In order to prevent the occurrence of distracting artifacts, so-called “halos”, the formation of the low-frequency signal component to be modified is formed in dependence upon the high-frequency image components.
摘要翻译：本发明涉及一种用于数字图像数据的自动对比度修正的图像处理方法。基于图像数据的数字图像信号形成至少一个低频信号和一个高频信号; 使用特征曲线函数修改低频信号分量; 然后将经修改的低频信号再次加到高频信号分量。为了防止分散的伪影的发生，所谓的“光晕”，根据高频图像分量形成待修改的低频信号分量的形成。

6. 发明申请

US20110019151A1 Microscopy system for eye surgery 有权
标题翻译：眼科手术系统
公开(公告)号：US20110019151A1
公开(公告)日：2011-01-27
申请号：US12801780
申请日：2010-06-24
申请人： Thomas Schuhrke , Günter Meckes , Stefan Gräber , Keith Thornton
发明人： Thomas Schuhrke , Günter Meckes , Stefan Gräber , Keith Thornton
IPC分类号： A61B3/13 , A61B3/14 , A61B3/10
CPC分类号： A61B3/111 , A61B3/13 , G02B21/0012 , G06T7/73 , G06T2207/10056 , G06T2207/30041
摘要： The invention relates to an eye surgery microscopy system (1) having an imaging optic (14, 11) for the generation of the image of an object plane (15) and having an electronic image sensor (18), which detects the image of the object plane (15) and is connected to a computer unit (5) for the computation of the position of the center of a circular structure (44) of a patient eye (16). The computer unit (5) is designed for the computation of the position of a patient eye (16) outside of the center (52) of the circular structure (44) and provided with at least one marking (46, 48). The computer unit (5) determines the position of the at least one marking (46, 48) with reference to the computed center (52) by means of image processing via correlation with a comparison information, and an angular position of the at least one marking (46, 48) with reference to the computed center (52) by means of image processing.
摘要翻译：本发明涉及一种具有成像光学元件（14,11）的眼科手术显微镜系统（1），用于产生物体平面（15）的图像并具有电子图像传感器（18），该电子图像传感器检测物体平面（15）并且连接到计算机单元（5）以用于计算患者眼睛（16）的圆形结构（44）的中心的位置。计算机单元（5）被设计用于计算患者眼睛（16）在圆形结构（44）的中心（52）外部的位置并且设置有至少一个标记（46,48）。计算机单元（5）通过与比较信息的相关性的图像处理和参考所计算的中心（52）的至少一个角度位置来确定至少一个标记（46,48）的位置通过图像处理参考计算出的中心（52）来标记（46,48）。

7. 发明申请

US20100042000A1 Method for correcting the image data that represent the blood flow 审中-公开
标题翻译：用于校正表示血流的图像数据的方法
公开(公告)号：US20100042000A1
公开(公告)日：2010-02-18
申请号：US12462045
申请日：2009-07-28
申请人： Thomas Schuhrke , Guenter Meckes
发明人： Thomas Schuhrke , Guenter Meckes
IPC分类号： A61B6/00 , G06K9/00
CPC分类号： A61B5/0261 , A61B5/0275 , A61B90/20 , G06T7/0012 , G06T7/32 , G06T2207/10016 , G06T2207/10048 , G06T2207/30104
摘要： A method for correcting the image data representing the blood flow for the evaluation and quantitative representation of the blood flow in a tissue or vascular region is based on the signal of a contrast agent injected into the blood. Several individual images of the signal emitted by the tissue or vascular region are recorded and stored at successive points in time. At least two individual images are correlated and a shift vector is generated based on the correlation. Thereafter, the image data of the individual images are shifted in relation to each other according to the shift vector.
摘要翻译：用于校正表示用于评价组织或血管区域中的血流的评估和定量表示的血流的图像数据的方法基于注射到血液中的造影剂的信号。由组织或血管区域发射的信号的几个单独图像在连续的时间点被记录并存储。至少两个单独的图像相关，并且基于相关性生成移位向量。此后，各个图像的图像数据根据移位矢量相对于彼此移位。

8. 发明授权

US08662667B2 Ophthalmologic visualization system 有权
标题翻译：眼科可视化系统
公开(公告)号：US08662667B2
公开(公告)日：2014-03-04
申请号：US12801689
申请日：2010-06-21
申请人： Thomas Schuhrke , Günter Meckes , Stefan Gräber , Keith Thornton
发明人： Thomas Schuhrke , Günter Meckes , Stefan Gräber , Keith Thornton
IPC分类号： A61B3/14
CPC分类号： A61B3/11 , A61B3/111 , A61B3/112 , A61B3/14 , G06K9/00604
摘要： A method determines the position and/or radius of the limbus and/or the position and/or radius of the pupil of a patient eye. In the method, an image of the patient eye is obtained and a plurality of different ring-shaped comparison objects having respective radii and respective centers are provided. The image is correlated with the plurality of comparison objects to yield a local best match between the image and the comparison objects when there is a coincidence of one of the ring-shaped comparison objects and a ring-shaped jump in brightness in the image having the same radius and the same center. The comparison objects having a local best match with the image are determined. Thereafter, the position of the center of the comparison object having a local best match with the image is selected as the position of the center of the limbus and/or the position of the center of the pupil.
摘要翻译：方法确定角膜缘的位置和/或半径和/或患者眼睛的瞳孔的位置和/或半径。在该方法中，获得患者眼睛的图像，并且提供具有各自的半径和各个中心的多个不同的环形比较对象。该图像与多个比较对象相关联，以便当存在一个环形比较对象之间的一个并且在具有该形状的比较对象的图像中的亮度的环形跳跃时，在图像和比较对象之间产生局部最佳匹配相同的半径和相同的中心。确定与图像具有局部最佳匹配的比较对象。此后，选择与图像具有局部最佳匹配的比较对象的中心的位置作为角膜缘中心的位置和/或瞳孔中心的位置。

9. 发明授权

US08308298B2 Microscopy system for eye surgery 有权
标题翻译：眼科手术系统
公开(公告)号：US08308298B2
公开(公告)日：2012-11-13
申请号：US12801780
申请日：2010-06-24
申请人： Thomas Schuhrke , Günter Meckes , Stefan Gräber , Keith Thornton
发明人： Thomas Schuhrke , Günter Meckes , Stefan Gräber , Keith Thornton
IPC分类号： A61B3/14 , A61B3/00
CPC分类号： A61B3/111 , A61B3/13 , G02B21/0012 , G06T7/73 , G06T2207/10056 , G06T2207/30041
摘要： The invention relates to an eye surgery microscopy system (1) having an imaging optic (14, 11) for the generation of the image of an object plane (15) and having an electronic image sensor (22), which detects the image of the object plane (15) and is connected to a computer unit (5) for the computation of the position of the center of a circular structure (44) of a patient eye (16). The computer unit (5) is designed for the computation of the position of a patient eye (16) outside of the center (52) of the circular structure (44) and provided with at least one marking (46, 48). The computer unit (5) determines the position of the at least one marking (46, 48) with reference to the computed center (52) by means of image processing via correlation with a comparison information, and an angular position of the at least one marking (46, 48) with reference to the computed center (52) by means of image processing.
摘要翻译：本发明涉及一种具有用于产生物体平面（15）的图像并具有电子图像传感器（22）的成像光学元件（14,11）的眼科手术显微镜系统（1），该电子图像传感器检测物体平面（15）并且连接到计算机单元（5）以用于计算患者眼睛（16）的圆形结构（44）的中心的位置。计算机单元（5）被设计用于计算患者眼睛（16）在圆形结构（44）的中心（52）外部的位置并且设置有至少一个标记（46,48）。计算机单元（5）通过与比较信息的相关性的图像处理和参考所计算的中心（52）的至少一个角度位置来确定至少一个标记（46,48）的位置通过图像处理参考计算出的中心（52）来标记（46,48）。

10. 发明申请

US20110028850A1 Process for quantitative display of blood flow 审中-公开
标题翻译：定量显示血流量的过程
公开(公告)号：US20110028850A1
公开(公告)日：2011-02-03
申请号：US12462038
申请日：2009-07-28
申请人： Thomas Schuhrke , Guenter Meckes , Joachim Steffen , Hans-Joachim Miesner , Frank Rudolph , Werner Nahm
发明人： Thomas Schuhrke , Guenter Meckes , Joachim Steffen , Hans-Joachim Miesner , Frank Rudolph , Werner Nahm
IPC分类号： A61B6/00 , A61B5/02
CPC分类号： A61B5/0261 , A61B5/0059 , A61B5/0275 , G06T7/0016 , G06T11/00 , G06T2207/10016 , G06T2207/10048 , G06T2207/30104
摘要： A method for the quantitative representation of the blood flow in a tissue or vascular region is based on the signal of a contrast agent injected into the blood. In the method, several individual images of the signal emitted by the tissue or vascular region are recorded at successive points in time and are stored. Based on the respective signal, a quantity characteristic for the blood flow and a quantity characteristic for the position of the blood vessels are determined for image areas of individual images. These quantities are represented superimposed for the respective image areas such that both the blood flow quantity and the position of the fine blood vessels become clearly visible in the representation and can be differentiated from the tissue.
摘要翻译：用于定量表示组织或血管区域中的血液流动的方法基于注射到血液中的造影剂的信号。在该方法中，在连续的时间点记录由组织或血管区域发射的信号的几个单独的图像，并被存储。基于各信号，针对各图像的图像区域确定血流的量特性和血管位置的量特征。这些量对于各个图像区域被叠加，使得血液流量和细小血管的位置在表示中变得清晰可见，并且可以与组织区分开。

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