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1. 发明授权

US08304520B2 Labeled fusion protein 失效
标题翻译：标记融合蛋白
公开(公告)号：US08304520B2
公开(公告)日：2012-11-06
申请号：US12517964
申请日：2007-12-05
申请人： Eisaku Katayama , Takashi Murayama , Taku Kashiyama , Takuya Kobayashi
发明人： Eisaku Katayama , Takashi Murayama , Taku Kashiyama , Takuya Kobayashi
IPC分类号： C07K14/00 , C07K1/00 , C12P21/06
CPC分类号： C12N15/62 , C07K14/47 , C07K2319/23 , G01N33/532
摘要： The present invention aims at providing a general-purpose experimental tool which specifically binds to a macromolecular substance that will be a receptor for a specific ligand such as drug, and is applicable throughout various processes to explore the nature of the macromolecular substance. In order to achieve this object, a molecular module has been developed which binds to a target compound and is used for purifying or labeling the target compound, wherein the molecular module has a rod-like spacer substance, an interacting substance that interacts with the target compound, a tag and a labeling substance, the interacting substance being positioned at one end of the rod-like spacer substance, and the tag and the labeling substance being positioned at the other end of the rod-like spacer substance.
摘要翻译：本发明的目的在于提供一种特异性结合作为特定配体如药物的受体的大分子物质的通用实验工具，并且可用于各种过程以探索大分子物质的性质。为了实现该目的，开发了一种结合目标化合物并用于纯化或标记目标化合物的分子模块，其中分子模块具有棒状间隔物质，与靶标相互作用的相互作用物质化合物，标签和标记物质，所述相互作用物质位于所述棒状间隔物质的一端，并且所述标签和所述标记物质位于所述棒状间隔物质的另一端。

2. 发明申请

US20100105882A1 MOLECULAR MODULE 失效
标题翻译：分子模块
公开(公告)号：US20100105882A1
公开(公告)日：2010-04-29
申请号：US12517964
申请日：2007-12-05
申请人： Eisaku Katayama , Takashi Murayama , Taku Kashiyama , Takuya Kobayashi
发明人： Eisaku Katayama , Takashi Murayama , Taku Kashiyama , Takuya Kobayashi
IPC分类号： C07K1/14 , C07K14/00
CPC分类号： C12N15/62 , C07K14/47 , C07K2319/23 , G01N33/532
摘要： The present invention aims at providing a general-purpose experimental tool which specifically binds to a macromolecular substance that will be a receptor for a specific ligand such as drug, and is applicable throughout various processes to explore the nature of the macromolecular substance. In order to achieve this object, a molecular module has been developed which binds to a target compound and is used for purifying or labeling the target compound, wherein the molecular module has a rod-like spacer substance, an interacting substance that interacts with the target compound, a tag and a labeling substance, the interacting substance being positioned at one end of the rod-like spacer substance, and the tag and the labeling substance being positioned at the other end of the rod-like spacer substance.
摘要翻译：本发明的目的在于提供一种特异性结合作为特定配体如药物的受体的大分子物质的通用实验工具，并且可用于各种过程以探索大分子物质的性质。为了实现该目的，开发了一种结合目标化合物并用于纯化或标记目标化合物的分子模块，其中分子模块具有棒状间隔物质，与靶标相互作用的相互作用物质化合物，标签和标记物质，所述相互作用物质位于所述棒状间隔物质的一端，并且所述标签和所述标记物质位于所述棒状间隔物质的另一端。

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