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1. 发明申请

US20120090222A1 FUEL MANUFACTURING METHOD 审中-公开
标题翻译：燃料制造方法
公开(公告)号：US20120090222A1
公开(公告)日：2012-04-19
申请号：US13259037
申请日：2009-03-25
申请人： Takehiko Matsumura , Noritaka Hirose , Takako Izumi
发明人： Takehiko Matsumura , Noritaka Hirose , Takako Izumi
IPC分类号： C10L1/02
CPC分类号： C10L1/02 , C10G2300/1014 , C10G2300/1018 , C10G2300/805 , Y02E50/30 , Y02P30/20
摘要： The objective is to obtain fuel having high combustion calorie and superior handleability from a crude glycerin or a fatty acid mixture that have been discarded as industrial waste products. Disclosed is a fuel comprising a water-insolublized fatty acid substance obtained by water-insolubilizing a fatty acid that is contained in a crude glycerin or fatty acid mixtures that are produced as by-products in the process of producing a biofuel from an animal/plant-derived fat/oil. The water-insolublized fatty acid substance is preferably a water-insoluble fatty acid salt, particularly preferably a salt of a fatty acid with a divalent or trivalent metal ion.
摘要翻译：目的是获得作为工业废弃物被丢弃的粗甘油或脂肪酸混合物获得具有高燃烧热量和优异操作性的燃料。公开了一种燃料，其包含水不溶性脂肪酸物质，所述脂肪酸物质通过水分不溶于粗制甘油或脂肪酸混合物中所含的脂肪酸，所述粗甘油或脂肪酸混合物在从动物/植物生产生物燃料的过程中作为副产物生产得到的脂肪/油。水不溶性脂肪酸物质优选为水不溶性脂肪酸盐，特别优选为具有二价或三价金属离子的脂肪酸的盐。

2. 发明授权

US07660626B2 Iontophoresis device 失效
标题翻译：离子渗透装置
公开(公告)号：US07660626B2
公开(公告)日：2010-02-09
申请号：US11195364
申请日：2005-08-02
申请人： Akihiko Tanioka , Mie Minagawa , Kiyoshi Kanamura , Akihiko Matsumura , Mizuo Nakayama , Takehiko Matsumura , Hidero Akiyama
发明人： Akihiko Tanioka , Mie Minagawa , Kiyoshi Kanamura , Akihiko Matsumura , Mizuo Nakayama , Takehiko Matsumura , Hidero Akiyama
IPC分类号： A61N1/30
CPC分类号： A61N1/044 , A61N1/0436 , A61N1/0444
摘要： The present invention provides an iontophoresis device with high administration efficient of a drug. An iontophoresis device, including an active electrode structure including: an electrode to which a positive electrical potential is applied; a drug holding part for holding a drug solution containing positively charged drug ions, the drug holding part being placed on a front side of the electrode; a cellulose-based resin film placed on a front side of the drug holding part or a complex film composed of a cation exchange membrane and a cellulose-based resin film placed on a front side of the cation exchange membrane, the complex film being placed on a front side of the drug holding part, in which the drug ions are administered through the cellulose-based resin film.
摘要翻译：本发明提供了具有药物高效给药的离子电渗疗法装置。一种离子电渗疗法装置，包括有源电极结构，包括：施加正电位的电极; 用于保持含有带正电荷的药物离子的药液的药物保持部，药物保持部位于电极的前侧; 将放置在药物保持部的前侧的纤维素系树脂膜或配置在阳离子交换膜前侧的阳离子交换膜和纤维素系树脂膜构成的复合膜，将复合膜置于药物保持部的前侧，其中通过纤维素系树脂膜施用药物离子。

3. 发明申请

US20100030128A1 IONTOPHORESIS DEVICE 审中-公开
标题翻译： IONTOPHORESIS设备
公开(公告)号：US20100030128A1
公开(公告)日：2010-02-04
申请号：US12065851
申请日：2006-09-01
申请人： Kazuma Mitsuguchi , Mitsugu Yamauchi , Mizuo Nakayama , Takehiko Matsumura , Hidero Akiyama , Akihiko Matsumura
发明人： Kazuma Mitsuguchi , Mitsugu Yamauchi , Mizuo Nakayama , Takehiko Matsumura , Hidero Akiyama , Akihiko Matsumura
IPC分类号： A61N1/30
CPC分类号： A61N1/303
摘要： The transport efficiency of a drug using an iontophoresis device is increased using a negative pressure device.The iontophoresis device includes a working electrode assembly and a non-working electrode assembly for administering drug by iontophoresis. Each of the working electrode assembly and the non-working electrode assembly includes an adhesive surface configured to adhere to a biological interface. A DC electric power source is connected to the working electrode assembly and the non-working electrode assembly. The iontophoresis device further includes a negative pressure device integral with at least one of the working electrode assembly and the non-working electrode assembly and configured to maintain a negative pressure between the at least one of the working electrode assembly and the non-working electrode assembly and the biological interface.
摘要翻译：使用离子渗透装置的药物的输送效率使用负压装置增加。离子电渗装置包括工作电极组件和用于通过离子电渗疗法给药的非工作电极组件。工作电极组件和非工作电极组件中的每一个包括被配置为粘附到生物界面的粘合表面。直流电源连接到工作电极组件和非工作电极组件。离子电渗装置还包括与至少一个工作电极组件和非工作电极组件成一体的负压装置，并且构造成在工作电极组件和非工作电极组件中的至少一个之间保持负压和生物界面。

4. 发明申请

US20100016781A1 Iontophoresis device selecting drug to be administered on the basis of information form sensor 审中-公开
标题翻译：离子渗透装置选择基于信息形式传感器施用的药物
公开(公告)号：US20100016781A1
公开(公告)日：2010-01-21
申请号：US11991234
申请日：2006-08-29
申请人： Mizuo Nakayama , Takehiko Matsumura , Hidero Akiyama , Akihiko Matsumura
发明人： Mizuo Nakayama , Takehiko Matsumura , Hidero Akiyama , Akihiko Matsumura
IPC分类号： A61N1/30
CPC分类号： A61N1/303 , A61N1/0444 , A61N1/08
摘要： An iontophoresis device including an electric power source. A first electrode assembly is electrically coupled to the electric power source to transdermally administer an ionic drug to an organism via iontophoresis while a second electrode assembly is electrically coupled to the electric power source as a counter electrode to the first electrode assembly. A sensor may be positioned proximate an internal or external portion of the organism and operable to determine information used to select and deliver the ionic drug to the organism.
摘要翻译：一种离子电渗疗法装置，包括电源。第一电极组件电耦合到电源，以通过离子电渗将离子药物透皮施用于生物体，而第二电极组件作为与第一电极组件的对电极电耦合到电源。传感器可以定位在生物体的内部或外部附近，并且可操作以确定用于选择并将离子药物递送到生物体的信息。

5. 发明申请

US20090299264A1 Electrode Assembly for Dry Type Iontophoresis 审中-公开
标题翻译：干式离子导入电极组件
公开(公告)号：US20090299264A1
公开(公告)日：2009-12-03
申请号：US11992671
申请日：2006-09-28
申请人： Takehiko Matsumura , Mizuo Nakayama , Hidero Akiyama , Akihiko Matsumura
发明人： Takehiko Matsumura , Mizuo Nakayama , Hidero Akiyama , Akihiko Matsumura
IPC分类号： A61N1/30
CPC分类号： A61N1/0448 , A61N1/0444
摘要： An iontophoresis device capable of stably holding a drug for a long time period and of transdermally administering the drug at a high transport number during use. The iontophoresis device includes a drug holding portion to store the ionic drug in a dry state and at least an aqueous medium holding portion to store an aqueous medium. The drug holding portion exhibiting ion conductivity in response to a needle inserted into the aqueous medium holding portion from outside the electrode assembly such that the drug holding portion is supplied with the aqueous medium during use and the ionic drug dissolves in the aqueous medium.
摘要翻译：一种能够长时间稳定地保持药物并且在使用期间以高转运数量经皮给药的离子电渗疗装置。离子电渗装置包括药物保持部分，用于将离子药物储存在干燥状态，并且至少含有水性介质保持部分以存储水性介质。药物保持部分响应于从电极组件外部插入到水性介质保持部分中的针而显示离子传导性，使得在使用期间向药物保持部分供给水性介质，并且离子药物溶解在水性介质中。

6. 发明申请

US20070135754A1 ELECTRODE ASSEMBLY FOR IONTOPHORESIS FOR ADMINISTERING ACTIVE AGENT ENCLOSED IN NANOPARTICLE AND IONTOPHORESIS DEVICE USING THE SAME 审中-公开
标题翻译：电极组件用于管理用纳米颗粒和非离子表面活性剂包封的活性剂的静电放电
公开(公告)号：US20070135754A1
公开(公告)日：2007-06-14
申请号：US11537459
申请日：2006-09-29
申请人： Hidero Akiyama , Mizuo Nakayama , Takehiko Matsumura , Akihiko Matsumura
发明人： Hidero Akiyama , Mizuo Nakayama , Takehiko Matsumura , Akihiko Matsumura
IPC分类号： A61N1/30
CPC分类号： A61N1/0448 , A61N1/044 , A61N1/0444
摘要： An electrode assembly for iontophoresis may enable the administration of a non-ionic active agent ionized, or an active agent that is substantially insoluble in water, by iontophoresis. An electrode assembly used for iontophoresis may hold an active agent enclosed in an ionic nanoparticle.
摘要翻译：用于离子电渗疗法的电极组件可以通过离子电渗法施用电离的非离子活性剂或基本上不溶于水的活性剂。用于离子电渗疗法的电极组件可以包含封闭在离子纳米颗粒中的活性剂。

7. 发明申请

US20060173401A1 Iontophoresis device 失效
标题翻译：离子渗透装置
公开(公告)号：US20060173401A1
公开(公告)日：2006-08-03
申请号：US11195364
申请日：2005-08-02
申请人： Akihiko Tanioka , Mie Minagawa , Kiyoshi Kanamura , Akihiko Matsumura , Mizuo Nakayama , Takehiko Matsumura , Hidero Akiyama
发明人： Akihiko Tanioka , Mie Minagawa , Kiyoshi Kanamura , Akihiko Matsumura , Mizuo Nakayama , Takehiko Matsumura , Hidero Akiyama
IPC分类号： A61N1/30
CPC分类号： A61N1/044 , A61N1/0436 , A61N1/0444
摘要： The present invention provides an iontophoresis device with high administration efficient of a drug. An iontophoresis device, including an active electrode structure including: an electrode to which a positive electrical potential is applied; a drug holding part for holding a drug solution containing positively charged drug ions, the drug holding part being placed on a front side of the electrode; a cellulose-based resin film placed on a front side of the drug holding part or a complex film composed of a cation exchange membrane and a cellulose-based resin film placed on a front side of the cation exchange membrane, the complex film being placed on a front side of the drug holding part, in which the drug ions are administered through the cellulose-based resin film.
摘要翻译：本发明提供了具有药物高效给药的离子电渗疗法装置。一种离子电渗疗法装置，包括有源电极结构，包括：施加正电位的电极; 用于保持含有带正电荷的药物离子的药液的药物保持部，药物保持部位于电极的前侧; 将放置在药物保持部的前侧的纤维素系树脂膜或配置在阳离子交换膜前侧的阳离子交换膜和纤维素系树脂膜构成的复合膜，将复合膜置于药物保持部的前侧，其中通过纤维素系树脂膜施用药物离子。

8. 发明申请

US20090299265A1 Electrode Assembly for Iontophoresis Having Shape-Memory Separator and Iontophoresis Device Using the Same 审中-公开
标题翻译：具有形状记忆分离器和使用其的离子电渗装置的离子电渗电极组件
公开(公告)号：US20090299265A1
公开(公告)日：2009-12-03
申请号：US11992672
申请日：2006-10-02
申请人： Akihiko Tanioka , Mizuo Nakayama , Takehiko Matsumura , Hidero Akiyama , Akihiko Matsumura
发明人： Akihiko Tanioka , Mizuo Nakayama , Takehiko Matsumura , Hidero Akiyama , Akihiko Matsumura
IPC分类号： A61N1/30
CPC分类号： A61N1/0444 , A61N1/044 , A61N1/0448
摘要： An electrode assembly for iontophoresis including an electrode coupled to an electric power source device having a same polarity as that of the ionic drug in the electrode assembly, an electrolyte solution holding portion holding an electrolyte solution by being impregnated with the electrolyte solution, the electrolyte solution holding portion being placed adjacent to the electrode, a first ion exchange membrane operable to substantially pass ions having a polarity that is same as a polarity of the ionic drug and substantially block ions having a polarity that is opposite the polarity of the ionic drug, the first ion exchange membrane being placed adjacent to the electrolyte solution holding portion, a drug solution holding portion holding the ionic drug by being impregnated with the ionic drug, the drug solution holding portion being placed adjacent to the first ion exchange membrane, a second ion exchange membrane operable to substantially pass ions having a polarity that is opposite the polarity of the ionic drug and substantially block ions having a polarity that is the same as the polarity of the ionic drug, the second ion exchange membrane being placed adjacent to the drug solution holding portion, and a shape-memory separator capable of being transformed between a first and a second configuration to respectively allow passage of a substance and blocking of the substance, the shape-memory separator placed adjacent to at least one surface of the first ion exchange membrane.
摘要翻译：一种用于离子电渗疗法的电极组件，其包括与电极组件中的离子药物极性相同的电源装置的电极，通过浸渍电解质溶液保持电解质溶液的电解液保持部分，保持部分被放置成与电极相邻，第一离子交换膜可操作以基本上通过具有与离子药物的极性相同的极性的离子，并且基本上阻挡具有与离子药物的极性相反的极性的离子，第一离子交换膜与电解质溶液保持部相邻配置，通过浸渍离子性药物而保持离子性药物的药液保持部，药液保持部与第一离子交换膜相邻配置，第二离子交换膜可操作以基本上通过具有相反极性的离子 e离子药物的极性，并且基本上阻挡具有与离子药物的极性相同的极性的离子，第二离子交换膜邻近药物溶液保持部分放置，以及形状记忆分离器，其能够在第一和第二构型之间转换以分别允许物质的通过和物质的阻塞，所述形状记忆隔离物与第一离子交换膜的至少一个表面相邻放置。

9. 发明申请

US20090221951A1 IONTOPHORESIS DEVICE AND ELECTRIC POWER SOURCE FOR AN IONTOPHORESIS DEVICE 审中-公开
标题翻译：静电装置和电源的静电装置
公开(公告)号：US20090221951A1
公开(公告)日：2009-09-03
申请号：US12066362
申请日：2006-09-13
申请人： Mizuo Nakayama , Takehiko Matsumura , Hidero Akiyama , Akihiko Matsumura
发明人： Mizuo Nakayama , Takehiko Matsumura , Hidero Akiyama , Akihiko Matsumura
IPC分类号： A61N1/30
CPC分类号： A61N1/30
摘要： A drug may be administered in accordance with a daily living pattern of a patient and/or a circadian rhythm of the drug.An iontophoresis device includes a working electrode assembly and a non-working electrode assembly for administering a drug by iontophoresis and an electric power source connected to the working electrode assembly and the non-working electrode assembly. Current control circuitry programmably controls a current that flows to each of the electrode assemblies according to a set pattern, and the drug is released based at least in part on the current.
摘要翻译：可以根据患者的日常生活方式和/或药物的昼夜节律来施用药物。离子电渗装置包括工作电极组件和用于通过离子电渗疗法给药的非工作电极组件和连接到工作电极组件和非工作电极组件的电源。电流控制电路可编程地控制根据设定模式流向每个电极组件的电流，并且至少部分地基于电流释放药物。

10. 发明申请

US20090005721A1 PACKAGED IONTOPHORESIS SYSTEM 审中-公开
标题翻译：包装IOPOPHORESIS系统
公开(公告)号：US20090005721A1
公开(公告)日：2009-01-01
申请号：US12135901
申请日：2008-06-09
申请人： Mizuo Nakayama , Takehiko Matsumura , Tsutomu Shibata , Akihiro Ryuka
发明人： Mizuo Nakayama , Takehiko Matsumura , Tsutomu Shibata , Akihiro Ryuka
IPC分类号： A61N1/30
CPC分类号： B65D75/58 , A61N1/303
摘要： Provided is a packaged iontophoresis system 15 including: an iontophoresis system 10 including an apparatus body 50 for transdermally delivering an ionized drug by iontophoresis, and a connection part 70 extended from the apparatus body 50 and connected to the apparatus body 50 and a power source 60, the power source 60 supplying power to the apparatus body 50; a package material 80 hermetically packaging the apparatus body 50 and a portion of the connection part 70, by at least a part thereof being welded to the connection part 70; and a cutting guide 400 guiding a cutting line of the package material 80 so that the part of the package material 80 welded to the connection part 70 remains at the connection part 70 when the package material 80 is opened.
摘要翻译：提供了一种封装的离子电渗系统15，其包括：离子电渗系统10，其包括用于通过离子电渗法透皮地递送离子化药物的装置主体50;以及从装置主体50延伸并连接到装置主体50的连接部70和电源60 向设备主体50供电的电源60; 包装材料80将装置主体50和连接部70的一部分密封地包封，其至少一部分被焊接到连接部70; 以及导向包装材料80的切割线的切割引导件400，使得当包装材料80打开时，焊接到连接部70的包装材料80的一部分保留在连接部70。

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