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    • 1. 发明授权
    • Bisphosphine ligand
    • 双膦配体
    • US07569730B2
    • 2009-08-04
    • US12054917
    • 2008-03-25
    • Michimasa WatanabeYuhki TakeuchiTakahiro IsobeTadashi Takeuchi
    • Michimasa WatanabeYuhki TakeuchiTakahiro IsobeTadashi Takeuchi
    • C07F9/02B01J23/40
    • C07F9/5027C07F9/65517C07F9/65527C07F15/0073
    • A compound represented by the following general formula (I): [wherein R1 represents hydrogen atom, or an alkyl group, R2 represents a hydroxyalkyl group, or a triarylmethyloxyalkyl group, or R1 and R2 combine together to represent —C(R3)(R4)— (R3 and R4 represent hydrogen atom, an alkyl group, or hydroxyl group, or R3 and R4 may combine together to represent oxo group), or —C(R5)(R6)—O—C(R7)(R8)— (R5 to R8 represent hydrogen atom, an alkyl group, or hydroxyl group, or R5 and R6 may combine together to represent oxo group, and R7 and R8 may combine together to represent oxo group); Ar1 to Ar4 independently represent an aryl group (the aryl group may have 1 to 5 of the same or different substituents), *1 to *4 indicate asymmetric carbons, and configurations are cis between *1 and *2, cis between *3 and *4, and trans between *2 and *3]. An optically active phosphine ligand which can be easily synthesized and gives a transition metal complex showing superior asymmetric catalyst activity is provided.
    • 由以下通式(I)表示的化合物:[其中R1表示氢原子,或烷基,R2表示羟基烷基或三芳基甲氧基烷基,或R1和R2组合在一起表示-C(R3)(R4 ) - (R3和R4表示氢原子,烷基或羟基,或R3和R4可以结合在一起代表氧代基)或-C(R5)(R6)-OC(R7)(R8) - ( R5至R8表示氢原子,烷基或羟基,或R5和R6可以结合在一起代表氧基,R7和R8可以结合在一起代表氧代基); Ar 1〜Ar 4独立地表示芳基(芳基可以具有1〜5个相同或不同的取代基),* 1〜* 4表示不对称碳,构型在* 1和* 2之间是顺式的,* 3和 * 4,并且在* 2和* 3之间转换。 提供了可以容易地合成并产生显示出优异的不对称催化剂活性的过渡金属络合物的光学活性膦配体。
    • 2. 发明申请
    • NOVEL BISPHOSPHINE LIGAND
    • 新二苯膦配基
    • US20080242534A1
    • 2008-10-02
    • US12054917
    • 2008-03-25
    • Michimasa WATANABEYuhki TAKEUCHITakahiro ISOBETadashi TAKEUCHI
    • Michimasa WATANABEYuhki TAKEUCHITakahiro ISOBETadashi TAKEUCHI
    • C07F9/50C07F9/655C07F5/02B01J31/00
    • C07F9/5027C07F9/65517C07F9/65527C07F15/0073
    • A compound represented by the following general formula (I): [wherein R1 represents hydrogen atom, or an alkyl group, R2 represents a hydroxyalkyl group, or a triarylmethyloxyalkyl group, or R1 and R2 combine together to represent —C(R3)(R4)— (R3 and R4 represent hydrogen atom, an alkyl group, or hydroxyl group, or R3 and R4 may combine together to represent oxo group), or —C(R5)(R6)—O—C(R7)(R8)— (R5 to R8 represent hydrogen atom, an alkyl group, or hydroxyl group, or R5 and R6 may combine together to represent oxo group, and R7 and R8 may combine together to represent oxo group); Ar1 to Ar4 independently represent an aryl group (the aryl group may have 1 to 5 of the same or different substituents), *1 to *4 indicate asymmetric carbons, and configurations are cis between *1 and *2, cis between *3 and *4, and trans between *2 and *3]. An optically active phosphine ligand which can be easily synthesized and gives a transition metal complex showing superior asymmetric catalyst activity is provided.
    • 由以下通式(I)表示的化合物:[其中R 1表示氢原子或烷基,R 2表示羟基烷基或三芳基甲氧基烷基 ,或R 1和R 2结合在一起以表示-C(R 3)(R 4) - (R 3和R 4)代表氢原子,烷基或羟基,或R 3和R 4, 可以结合在一起代表氧代基)或-C(R 5)(R 6)-O(R 7)(R 7) (R 5) - (R 5至R 8)表示氢原子,烷基或羟基,或R 5, / SUP>和R 6可以结合在一起代表氧代基,R 7和R 8可以结合在一起代表氧代基); Ar 1至Ar 4独立地表示芳基(芳基可以具有1至5个相同或不同的取代基),* 1至* 4表示不对称碳, 并且构型在* 1和* 2之间是顺式的,* 3和* 4之间是顺式的,而在* 2和* 3之间是反式的。 提供了可以容易地合成并产生显示出优异的不对称催化剂活性的过渡金属络合物的光学活性膦配体。