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1. 发明授权

US07763012B2 Devices and methods for crossing a chronic total occlusion 有权
标题翻译：用于穿过慢性完全闭塞的装置和方法
公开(公告)号：US07763012B2
公开(公告)日：2010-07-27
申请号：US10653879
申请日：2003-09-02
申请人： Timothy B. Petrick , Steven N. Willard , Peter T. Keith , Dennis W. Wahr
发明人： Timothy B. Petrick , Steven N. Willard , Peter T. Keith , Dennis W. Wahr
IPC分类号： A61M25/00 , A61M37/00
CPC分类号： A61M25/0068 , A61B2017/22044 , A61B2017/22094 , A61M25/0026 , A61M25/0045 , A61M25/005 , A61M25/0052 , A61M25/0053 , A61M25/0069 , A61M25/008 , A61M25/0108 , A61M25/0136 , A61M25/0138 , A61M25/0147 , A61M25/02 , A61M25/104 , A61M2025/0081 , A61M2025/015 , A61M2025/09191 , A61M2025/1079
摘要： A catheter comprises an elongate tubular member having a proximal end and a distal end, and a deflectable tip at the distal end of the elongate tubular member. The deflectable tip comprises a first helical coil having a first diameter and a second helical coil having a second diameter, the first diameter being larger than the second diameter. The first and second helical coils are arranged in the manner of a double helix. When viewed in cross-section, the first helical coil and the second helical coil are aligned at a first point on a circumference of each coil and misaligned at a second point on the circumference of each coil, where the second point is approximately 180 degrees from the first point. In certain embodiments the catheter further includes a dilatation balloon. Methods of use for crossing a chronic total occlusion are also described.
摘要翻译：导管包括具有近端和远端的细长管状构件，以及在细长管状构件的远端处的可偏转尖端。可偏转尖端包括具有第一直径的第一螺旋线圈和具有第二直径的第二螺旋线圈，第一直径大于第二直径。第一和第二螺旋线圈以双螺旋的方式布置。当以横截面观察时，第一螺旋线圈和第二螺旋线圈在每个线圈的圆周上的第一点处对准，并且在每个线圈的圆周上的第二点处不对准，其中第二点距离第一点。在某些实施例中，导管还包括扩张气囊。还描述了用于穿过慢性完全闭塞的方法。

2. 发明授权

US09603588B2 Compressible arteriotomy locator for vascular closure devices and methods 有权
公开(公告)号：US09603588B2
公开(公告)日：2017-03-28
申请号：US13392619
申请日：2010-08-20
申请人： Scott A. Kramer , Valerie J. Glazier , Catherine A. Pipenhagen , Brian J. Edquist , Steven N. Willard
发明人： Scott A. Kramer , Valerie J. Glazier , Catherine A. Pipenhagen , Brian J. Edquist , Steven N. Willard
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B2017/00601 , A61B2017/00623 , A61B2017/0065 , A61B2017/00654 , A61B2017/00672
摘要： A tissue puncture locator device includes a temporary anchor configured for placement through a vascular puncture into a vessel. The temporary anchor includes a column member that defines a lumen. The temporary anchor is movable between an uncompressed position and a compressed position, wherein in the compressed poition a portion of the column member protrudes radially outward. The column member may include a reduced thickness portion, wherein the column member protrudes radially outward at the reduced thickness portion. The column member, when expanded radially outward within the vessel, is sized to limit retraction of the temporary anchor through the vascular puncture.

3. 发明申请

US20120283770A1 COMPRESSIBLE ARTERIOTOMY LOCATOR FOR VASCULAR CLOSURE DEVICES AND METHODS 有权
标题翻译：用于血管闭合装置和方法的可压缩的动静脉定位器
公开(公告)号：US20120283770A1
公开(公告)日：2012-11-08
申请号：US13392619
申请日：2010-08-20
申请人： Scott A. Kramer , Valerie J. Glazier , Catherine A. Pipenhagen , Brian J. Edquist , Steven N. Willard
发明人： Scott A. Kramer , Valerie J. Glazier , Catherine A. Pipenhagen , Brian J. Edquist , Steven N. Willard
IPC分类号： A61B17/03
CPC分类号： A61B17/0057 , A61B2017/00601 , A61B2017/00623 , A61B2017/0065 , A61B2017/00654 , A61B2017/00672
摘要： A tissue puncture locator device includes a temporary anchor configured for placement through a vascular puncture into a vessel. The temporary anchor includes a column member that defines a lumen. The temporary anchor is movable between an uncompressed position and a compressed position, wherein in the compressed position a portion of the column member protrudes radially outward. The column member may include a reduced thickness portion, wherein the column member protrudes radially outward at the reduced thickness portion. The column member, when expanded radially outward within the vessel, is sized to limit retraction of the temporary anchor through the vascular puncture.
摘要翻译：组织穿刺定位装置包括临时锚定构件，用于穿过血管穿刺进入血管。临时锚固体包括限定内腔的柱构件。临时锚固件可在未压缩位置和压缩位置之间移动，其中在压缩位置中，柱构件的一部分径向向外突出。柱构件可以包括减小的厚度部分，其中柱构件在厚度减小部分处径向向外突出。柱构件在容器内径向向外扩张时的尺寸设定为限制临时锚固件通过血管穿刺的缩回。

4. 发明申请

US20090318835A1 STEERABLE GUIDE WIRE WITH TORSIONALLY STABLE TIP 有权
标题翻译：可转向导线，扭矩稳定
公开(公告)号：US20090318835A1
公开(公告)日：2009-12-24
申请号：US12484910
申请日：2009-06-15
申请人： Thomas V. Ressemann , Peter T. Keith , Steven N. Willard , Peter J. Ness , Steven S. Hackett
发明人： Thomas V. Ressemann , Peter T. Keith , Steven N. Willard , Peter J. Ness , Steven S. Hackett
IPC分类号： A61M25/09
CPC分类号： A61M25/09 , A61M25/0133 , A61M25/09025 , A61M2025/09083 , A61M2025/09175
摘要： A steerable guide wire includes a core wire having a proximal end and a distal end. A braided filament is affixed to the distal end of the core wire. An outer coil surrounds at least a portion of the core wire and the braided filament. A proximal end of the braided filament is secured to a distal end of the coil. By locating the braided filament in the distal tip portion of the guide wire, a guide wire is provided that is highly flexible, has a high degree of tensile integrity, and is highly steerable, even in tortuous vasculature. Filter and balloon catheters having braided filaments at the distal end are also described.
摘要翻译：可导向的导丝线包括具有近端和远端的芯线。编织丝固定在芯线的远端。外部线圈围绕芯线和编织细丝的至少一部分。编织丝的近端固定到线圈的远端。通过将编织丝定位在导丝的远侧末端部分，提供了一种导丝，其具有高柔性，具有高度的拉伸完整性，并且即使在曲折的脉管系统中也是高度可操纵的。还描述了在远端具有编织细丝的过滤器和球囊导管。

5. 发明授权

US06171233B2 Pressure-responsive lockout valve and method of use 有权
标题翻译：压力响应闭锁阀及使用方法
公开(公告)号：US06171233B2
公开(公告)日：2001-01-09
申请号：US09191401
申请日：1998-11-12
申请人： Steven N. Willard
发明人： Steven N. Willard
IPC分类号： A61F500
CPC分类号： A61F2/26
摘要： A lockout valve for an inflatable penile prosthesis which responds to internal fluid pressure. The lockout valve comprises a housing having inlet and outlet ports, an interior chamber, an apertured valve seat, and a poppet biased toward the closed position. The inlet communicates with the prosthesis reservoir, and the outlet communicates with the interior chamber and the prosthesis pump. The housing includes a flexible diaphragm which moves toward the poppet when flexed inwardly. Fluid pressure through the inlet port urges the poppet into sealing engagement against the valve seat, therefore closing the lockout valve. Negative fluid pressure applied to the interior chamber from the outlet port (when the pump is actuated) causes the diaphragm to flex inwardly and contact the poppet to open the valve. The lockout valve operates like a check valve when subject to reverse flow.
摘要翻译：一种用于对内部流体压力作出响应的可膨胀阴茎假体的闭锁阀。锁定阀包括具有入口和出口的壳体，内部室，有孔阀座和朝向关闭位置偏压的提升阀。入口与假体储存器连通，并且出口与内部腔室和假体泵连通。壳体包括柔性隔膜，当向内弯曲时，该隔膜向着提升阀移动。通过入口的流体压力促使提升阀与阀座密封接合，从而关闭锁定阀。从出口（当泵被致动时）施加到内部室的负流体压力导致隔膜向内弯曲并接触提升阀以打开阀。当反向流动时，闭锁阀就像止回阀一样工作。

6. 发明授权

US08353850B2 Steerable guide wire with torsionally stable tip 有权
标题翻译：导向扭矩稳定的导丝
公开(公告)号：US08353850B2
公开(公告)日：2013-01-15
申请号：US12484910
申请日：2009-06-15
申请人： Thomas V Ressemann , Peter T Keith , Steven N Willard , Peter J Ness , Steven S. Hackett
发明人： Thomas V Ressemann , Peter T Keith , Steven N Willard , Peter J Ness , Steven S. Hackett
IPC分类号： A61B5/00
CPC分类号： A61M25/09 , A61M25/0133 , A61M25/09025 , A61M2025/09083 , A61M2025/09175
摘要： A steerable guide wire includes a core wire having a proximal end and a distal end. A braided filament is affixed to the distal end of the core wire. An outer coil surrounds at least a portion of the core wire and the braided filament. A proximal end of the braided filament is secured to a distal end of the coil. By locating the braided filament in the distal tip portion of the guide wire, a guide wire is provided that is highly flexible, has a high degree of tensile integrity, and is highly steerable, even in tortuous vasculature. Filter and balloon catheters having braided filaments at the distal end are also described.
摘要翻译：可导向的导丝线包括具有近端和远端的芯线。编织丝固定在芯线的远端。外部线圈围绕芯线和编织细丝的至少一部分。编织丝的近端固定到线圈的远端。通过将编织丝定位在导丝的远侧末端部分，提供了一种导丝，其具有高柔性，具有高度的拉伸完整性，并且即使在曲折的脉管系统中也是高度可操纵的。还描述了在远端具有编织细丝的过滤器和球囊导管。

7. 发明授权

US5851176A Pressure-responsive lockout valve and method of use 失效
标题翻译：压力响应闭锁阀及使用方法
公开(公告)号：US5851176A
公开(公告)日：1998-12-22
申请号：US681859
申请日：1996-07-29
申请人： Steven N. Willard
发明人： Steven N. Willard
IPC分类号： A61F2/26
CPC分类号： A61F2/26
摘要： A lockout valve for an inflatable penile prosthesis which responds to internal fluid pressure. The lockout valve comprises a housing having inlet and outlet ports, an interior chamber, an apertured valve seat, and a poppet biased toward the closed position. The inlet communicates with the prosthesis reservoir, and the outlet communicates with the interior chamber and the prosthesis pump. The housing includes a flexible diaphragm which moves toward the poppet when flexed inwardly. Fluid pressure through the inlet port urges the poppet into sealing engagement against the valve seat, therefore closing the lockout valve. Negative fluid pressure applied to the interior chamber from the outlet port (when the pump is actuated) causes the diaphragm to flex inwardly and contact the poppet to open the valve. The lockout valve operates like a check valve when subject to reverse flow.
摘要翻译：一种用于对内部流体压力作出响应的可膨胀阴茎假体的闭锁阀。锁定阀包括具有入口和出口的壳体，内部室，有孔阀座和朝向关闭位置偏压的提升阀。入口与假体储存器连通，并且出口与内部腔室和假体泵连通。壳体包括柔性隔膜，当向内弯曲时，该隔膜向着提升阀移动。通过入口的流体压力促使提升阀与阀座密封接合，从而关闭锁定阀。从出口（当泵被致动时）施加到内部室的负流体压力导致隔膜向内弯曲并接触提升阀以打开阀。当反向流动时，闭锁阀就像止回阀一样工作。

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