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1. 发明申请

US20100049271A1 IMPLANTABLE MEDICAL DEVICE WITH AUTOMATIC SENSING ADJUSTMENT 失效
标题翻译：具有自动感应调节的可植入医疗器械
公开(公告)号：US20100049271A1
公开(公告)日：2010-02-25
申请号：US12560008
申请日：2009-09-15
申请人： Steve Hofstadter , Christopher Koch , Mark W. Kroll
发明人： Steve Hofstadter , Christopher Koch , Mark W. Kroll
IPC分类号： A61N1/08
CPC分类号： A61N1/3702 , A61N1/3688
摘要： An implantable medical device system that senses physiologic processes via multiple sensor signal configurations. The device can further process the sensor configurations to obtain additional processed signal configurations. The device can utilize the processed configurations for ongoing sensing of the physiologic process. The device can also automatically evaluate the multiple sensor configurations as well as the processed configurations and select the configuration offering the best signal discrimination to reduce oversensing or erroneously interpreting secondary characteristics of the physiologic process as corresponding to primary characteristics of the process as in double-counting. The signal discrimination can be evaluated as an absolute margin and/or a ratio between amplitudes of the primary and secondary characteristics. The signal discrimination can also be evaluated based at least in part on a calculated mean and standard deviation according to each configuration.
摘要翻译：可植入式医疗设备系统，通过多个传感器信号配置感测生理过程。该装置可以进一步处理传感器配置以获得额外的处理信号配置。该设备可以利用经处理的配置来持续感测生理过程。该设备还可以自动评估多个传感器配置以及处理的配置，并选择提供最佳信号辨别的配置，以减少过敏或错误地解释生理过程的次要特征，如对应于过程的主要特征，如双重计数。信号辨别可以被评估为绝对余量和/或初级和次级特征幅度之间的比值。还可以至少部分地根据每个配置的计算的平均值和标准偏差来评估信号鉴别。

2. 发明授权

US07283871B1 Self adjusting optimal waveforms 有权
标题翻译：自适应最佳波形
公开(公告)号：US07283871B1
公开(公告)日：2007-10-16
申请号：US11102002
申请日：2005-04-07
申请人： Steve Hofstadter , Mark W. Kroll
发明人： Steve Hofstadter , Mark W. Kroll
IPC分类号： A61N1/39
CPC分类号： A61N1/3906
摘要： An exemplary method includes detecting fibrillation, measuring impedance of a defibrillation circuit that includes myocardial tissue, determining one or more defibrillation shock parameters based at least in part on the impedance, delivering a defibrillation shock using the one or more defibrillation shock parameters and, if the shock was unsuccessful, adjusting a membrane time constant and determining one or more new defibrillation shock parameters based at least in part on the adjusted membrane time constant. Various other exemplary methods are disclosed as well as various exemplary devices, systems, etc.
摘要翻译：示例性方法包括检测原纤维化，测量包括心肌组织的除颤电路的阻抗，至少部分地基于阻抗确定一个或多个除颤冲击参数，使用一个或多个去纤维颤动参数递送除颤休克，以及如果冲击不成功，调整膜时间常数并且至少部分地基于调整的膜时间常数来确定一种或多种新的除颤冲击参数。公开了各种其它示例性方法以及各种示例性装置，系统等

3. 发明授权

US08060200B2 Self-adjusting optimal waveforms 有权
标题翻译：自适应最优波形
公开(公告)号：US08060200B2
公开(公告)日：2011-11-15
申请号：US12131736
申请日：2008-06-02
申请人： Steve Hofstadter , Mark W. Kroll
发明人： Steve Hofstadter , Mark W. Kroll
IPC分类号： A61N1/39
CPC分类号： A61N1/3937 , A61B5/053 , A61N1/3906 , A61N1/3912
摘要： An exemplary method includes detecting fibrillation, measuring impedance of a defibrillation circuit that includes myocardial tissue, determining one or more defibrillation shock parameters based at least in part on the impedance, delivering a defibrillation shock using the one or more defibrillation shock parameters and, if the shock was unsuccessful, adjusting a membrane time constant and determining one or more new defibrillation shock parameters based at least in part on the adjusted membrane time constant. Various other exemplary methods are disclosed as well as various exemplary devices, systems, etc.
摘要翻译：示例性方法包括检测原纤维化，测量包括心肌组织的除颤电路的阻抗，至少部分地基于阻抗确定一个或多个除颤冲击参数，使用一个或多个去纤维颤动参数递送除颤休克，以及如果冲击不成功，调整膜时间常数并且至少部分地基于调整的膜时间常数来确定一种或多种新的除颤冲击参数。公开了各种其它示例性方法以及各种示例性装置，系统等

4. 发明授权

US07610090B1 Implantable medical device with automatic sensing adjustment 有权
标题翻译：具有自动感应调节功能的植入式医疗设备
公开(公告)号：US07610090B1
公开(公告)日：2009-10-27
申请号：US11366929
申请日：2006-03-01
申请人： Steve Hofstadter , Christopher Koch , Mark W. Kroll
发明人： Steve Hofstadter , Christopher Koch , Mark W. Kroll
IPC分类号： A61N1/08
CPC分类号： A61N1/3702 , A61N1/3688
摘要： An implantable medical device system that senses physiologic processes via multiple sensor signal configurations. The device can further process the sensor configurations to obtain additional processed signal configurations. The device can utilize the processed configurations for ongoing sensing of the physiologic process. The device can also automatically evaluate the multiple sensor configurations as well as the processed configurations and select the configuration offering the best signal discrimination to reduce oversensing or erroneously interpreting secondary characteristics of the physiologic process as corresponding to primary characteristics of the process as in double-counting. The signal discrimination can be evaluated as an absolute margin and/or a ratio between amplitudes of the primary and secondary characteristics. The signal discrimination can also be evaluated based at least in part on a calculated mean and standard deviation according to each configuration.
摘要翻译：可植入式医疗设备系统，通过多个传感器信号配置感测生理过程。该装置可以进一步处理传感器配置以获得额外的处理信号配置。该设备可以利用经处理的配置来持续感测生理过程。该设备还可以自动评估多个传感器配置以及处理的配置，并选择提供最佳信号辨别的配置，以减少过敏或错误地解释生理过程的次要特征，如对应于过程的主要特征，如双重计数。信号辨别可以被评估为绝对余量和/或初级和次级特征幅度之间的比值。还可以至少部分地根据每个配置的计算的平均值和标准偏差来评估信号鉴别。

5. 发明授权

US07398122B1 Self adjusting optimal waveforms 有权
标题翻译：自适应最佳波形
公开(公告)号：US07398122B1
公开(公告)日：2008-07-08
申请号：US11102331
申请日：2005-04-07
申请人： Steve Hofstadter , Mark W. Kroll
发明人： Steve Hofstadter , Mark W. Kroll
IPC分类号： A61N1/39
CPC分类号： A61N1/3937 , A61B5/053 , A61N1/3906 , A61N1/3912
摘要： An exemplary method includes detecting fibrillation, measuring impedance of a defibrillation circuit that includes myocardial tissue, determining one or more defibrillation shock parameters based at least in part on the impedance, delivering a defibrillation shock using the one or more defibrillation shock parameters and, if the shock was unsuccessful, adjusting a membrane time constant and determining one or more new defibrillation shock parameters based at least in part on the adjusted membrane time constant. Various other exemplary methods are disclosed as well as various exemplary devices, systems, etc.
摘要翻译：示例性方法包括检测原纤维化，测量包括心肌组织的除颤电路的阻抗，至少部分地基于阻抗确定一个或多个除颤冲击参数，使用一个或多个去纤维颤动参数递送除颤休克，以及如果冲击不成功，调整膜时间常数并且至少部分地基于调整的膜时间常数来确定一种或多种新的除颤冲击参数。公开了各种其它示例性方法以及各种示例性装置，系统等

6. 发明授权

US08750972B2 Implantable medical device with automatic sensing adjustment 失效
标题翻译：具有自动感应调节功能的植入式医疗设备
公开(公告)号：US08750972B2
公开(公告)日：2014-06-10
申请号：US12560008
申请日：2009-09-15
申请人： Steve Hofstadter , Christopher Koch , Mark W. Kroll
发明人： Steve Hofstadter , Christopher Koch , Mark W. Kroll
IPC分类号： A61N1/08
CPC分类号： A61N1/3702 , A61N1/3688
摘要： An implantable medical device system that senses physiologic processes via multiple sensor signal configurations. The device can further process the sensor configurations to obtain additional processed signal configurations. The device can utilize the processed configurations for ongoing sensing of the physiologic process. The device can also automatically evaluate the multiple sensor configurations as well as the processed configurations and select the configuration offering the best signal discrimination to reduce oversensing or erroneously interpreting secondary characteristics of the physiologic process as corresponding to primary characteristics of the process as in double-counting. The signal discrimination can be evaluated as an absolute margin and/or a ratio between amplitudes of the primary and secondary characteristics. The signal discrimination can also be evaluated based at least in part on a calculated mean and standard deviation according to each configuration.
摘要翻译：可植入式医疗设备系统，通过多个传感器信号配置感测生理过程。该装置可以进一步处理传感器配置以获得额外的处理信号配置。该设备可以利用经处理的配置来持续感测生理过程。该设备还可以自动评估多个传感器配置以及处理的配置，并选择提供最佳信号辨别的配置，以减少过敏或错误地解释生理过程的次要特征，如对应于过程的主要特征，如双重计数。信号辨别可以被评估为绝对余量和/或初级和次级特征幅度之间的比值。还可以至少部分地根据每个配置的计算的平均值和标准偏差来评估信号鉴别。

7. 发明申请

US20080249582A1 SELF-ADJUSTING OPTIMAL WAVEFORMS 有权
标题翻译：自调整最佳波形
公开(公告)号：US20080249582A1
公开(公告)日：2008-10-09
申请号：US12131736
申请日：2008-06-02
申请人： Steve Hofstadter , Mark W. Hroll
发明人： Steve Hofstadter , Mark W. Hroll
IPC分类号： A61N1/00
CPC分类号： A61N1/3937 , A61B5/053 , A61N1/3906 , A61N1/3912
摘要： An exemplary method includes detecting fibrillation, measuring impedance of a defibrillation circuit that includes myocardial tissue, determining one or more defibrillation shock parameters based at least in part on the impedance, delivering a defibrillation shock using the one or more defibrillation shock parameters and, if the shock was unsuccessful, adjusting a membrane time constant and determining one or more new defibrillation shock parameters based at least in part on the adjusted membrane time constant. Various other exemplary methods are disclosed as well as various exemplary devices, systems, etc.
摘要翻译：示例性方法包括检测原纤维化，测量包括心肌组织的除颤电路的阻抗，至少部分地基于阻抗确定一个或多个除颤冲击参数，使用一个或多个去纤维颤动参数递送除颤休克，以及如果冲击不成功，调整膜时间常数并且至少部分地基于调整的膜时间常数来确定一种或多种新的除颤冲击参数。公开了各种其它示例性方法以及各种示例性装置，系统等

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