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    • 3. 发明授权
    • Method of restricting turns at vehicle intersections
    • 限制车辆十字路口转弯的方法
    • US08917190B1
    • 2014-12-23
    • US13748554
    • 2013-01-23
    • Stephen Waller Melvin
    • Stephen Waller Melvin
    • G08G1/07
    • G08G1/07G08G1/095
    • A method of restricting turns at vehicle intersections imposes a policy that is dynamic and congestion based. Vehicle turns are allowed only to the extent that such a maneuver does not cause a hindrance to other vehicles traveling the same direction that are not turning. A hindrance may be defined in a variety of ways based on whether other vehicles are substantially impeded in their progress. In this way, such a “no hinder” turn restriction is dependent on actual driving conditions and allows for more efficient movement of traffic in both heavily congested and light driving conditions. A no hinder turn restriction may be combined with or may replace other types of turn restrictions and may be utilized for both left and right turns and for streets with single or multiple lanes.
    • 一种限制车辆交叉点转弯的方法强加了一种基于动态和拥塞的策略。 允许车辆转弯仅在这种机动性不会妨碍其他车辆行驶不转动相同方向的程度上。 基于其他车辆在进行中是否受到严重阻碍,可能会以各种方式界定障碍。 以这种方式,这种“无阻碍”的转弯限制取决于实际驾驶条件,并允许在拥挤和轻型驾驶条件下更有效地行驶车辆。 不阻碍转弯限制可以与其他类型的转弯限制相结合或者可以替代其他类型的转弯限制,并且可以用于左转弯和右转弯以及具有单车道或多车道的街道。
    • 5. 发明授权
    • Endpoint activity logging
    • 端点活动记录
    • US08301753B1
    • 2012-10-30
    • US11426687
    • 2006-06-27
    • Stephen Waller Melvin
    • Stephen Waller Melvin
    • G06F15/173
    • H04L61/103H04L61/2015H04L61/2514H04L61/6022H04L63/04H04L63/162
    • The ability to identify a specific machine associated with activity taking place on the Internet is provided. This involves recording the association between MAC addresses, which are uniquely associated with endpoints, and local IP addresses, the recording of the association between local IP addresses and port numbers with public IP addresses and port numbers, and the recording of public IP addresses and source port numbers associated with public activity. By recording this information and correlating it, in real-time or in a post-processing step, the specific machine associated with public activity can be determined.
    • 提供了识别与Internet上发生的活动相关联的特定机器的能力。 这涉及记录与端点唯一相关的MAC地址与本地IP地址之间的关联,本地IP地址与具有公共IP地址和端口号的端口号之间的关联的记录以及公共IP地址和源的记录 与公共活动相关联的端口号。 通过记录该信息并将其与实时或后处理步骤相关联,可以确定与公共活动相关联的特定机器。
    • 6. 发明授权
    • Streptococcus equi strain
    • 马链球菌菌株
    • US08187610B2
    • 2012-05-29
    • US12864034
    • 2009-01-20
    • Andrew Stephen WallerCarl RobinsonZoe Heather
    • Andrew Stephen WallerCarl RobinsonZoe Heather
    • A61K39/09C12N1/21C12N15/00A61P37/04A61P31/04
    • A61K39/09A61K2039/521A61K2039/552
    • The invention provides Streptococcus vaccine strains (e.g. S. equi which is causative of ‘strangles’) comprising the following modifications in their genomes: (i) attenuation of one or more essential biosynthetic genes, (ii) attenuation of one or more genes which encode a haemolytic toxin, or protein involved in the production thereof, plus preferably any one, two, or most preferably three of the following modifications: (iii) attenuation of one or more genes which encode a protein responsible for immune evasion (iv) modification of one or more genes such as to permit serological discrimination of the vaccine strain based on analysis of a protein encoded by said genes, and (v) attenuation of one or more genes which encode an enzyme responsible for recombination repair of the genome. The invention provides inter alia live attenuated vaccine strains which generate an immune response to multiple protective epitopes presented in a context resembling the live pathogen.
    • 本发明提供了链球菌疫苗菌株(例如,引起“扼杀”的马氏足疟原虫),其包含其基因组中的以下修饰:(i)减少一种或多种必需生物合成基因,(ii)减少一个或多个编码的基因 溶血素毒素或参与其生产的蛋白质,优选任何一种,两种,或最优选三种以下修饰:(iii)减少编码负责免疫逃避的蛋白质的一种或多种基因(iv) 基于对由所述基因编码的蛋白质的分析来允许对疫苗株进行血清学鉴定的一个或多个基因,以及(v)减少编码负责基因组重组修复的酶的一个或多个基因。 本发明特别提供减毒疫苗菌株,其产生对类似于活病原体的上下文中呈现的多种保护性表位的免疫应答。
    • 7. 发明授权
    • Headlamp alignment detection using a network of independent sensor units
    • 使用独立传感器单元网络的前照灯对准检测
    • US07876427B1
    • 2011-01-25
    • US12355779
    • 2009-01-17
    • Stephen Waller Melvin
    • Stephen Waller Melvin
    • G01J1/00
    • G01M11/064
    • Headlamp alignment is detected using a collection of intelligent, independent sensor units, each of which incorporates a vertical array of sensing elements capable of detecting headlamp illumination. The sensor units are networked together and can be coupled to a host controller. The host controller can provide a user interface via a touch screen and a Web server, and can further communicate with a plant network for interfacing with manufacturing databases. The network of sensor units can accommodate four or more sensors, which allows multiple vehicles and multiple headlamp types to be audited without physical movement of the sensor units. The sensor units are low in power consumption and can receive power over the same cable providing network communication. Incorporation of non-volatile memory within the sensor units allows factory data to be recorded within each sensor unit and permits convenient replacement of units in the field.
    • 使用智能独立的传感器单元的集合检测前照灯对准,每个传感器单元包括能够检测前照灯照明的垂直阵列的感测元件。 传感器单元联网在一起,并且可以耦合到主机控制器。 主机控制器可以经由触摸屏和Web服务器提供用户界面,并且可进一步与工厂网络通信以与制造数据库进行接口。 传感器单元的网络可以容纳四个或更多个传感器,其允许在不传感器单元的物理移动的情况下审核多个车辆和多个前照灯类型。 传感器单元功耗低,可以通过提供网络通信的同一电缆接收电力。 在传感器单元内部结合非易失性存储器允许在每个传感器单元内记录工厂数据,并且可以方便地更换现场的单元。
    • 8. 发明授权
    • Unique identifier validation
    • 唯一标识符验证
    • US07668954B1
    • 2010-02-23
    • US11426699
    • 2006-06-27
    • Stephen Waller Melvin
    • Stephen Waller Melvin
    • G06F15/173
    • H04L63/10H04L29/12028H04L29/12226H04L29/12367H04L29/12839H04L61/103H04L61/2015H04L61/2514H04L61/6022H04L63/0442H04L63/162
    • The ability to validate the identity of a specific machine connected to a computerized network is provided. This involves validating MAC addresses, or any other form of digital identification that should be uniquely associated with a computer or user. This take places through the use of an identification registrar and an identification valuator. Such an identification validation system can be used with MAC addresses and can be used in conjunction with a system that records other information necessary to associate activity on a computer network with the validated MAC address. In this way, the specific computer or user associated with network activity can be determined, and it can be guaranteed that the identification has not been tampered with.
    • 提供了验证连接到计算机化网络的特定机器的身份的能力。 这涉及验证MAC地址或任何其他形式的数字标识,应与计算机或用户唯一相关联。 这通过使用识别注册商和身份评估者来进行。 这样的识别验证系统可以与MAC地址一起使用,并且可以与记录用于将计算机网络上的活动与验证的MAC地址相关联的其他信息的系统结合使用。 以这种方式,可以确定与网络活动相关联的特定计算机或用户,并且可以保证该识别尚未被篡改。
    • 9. 发明申请
    • BARRIER SYSTEM TO REDUCE THE RATES OF LINE-RELATED INFECTIONS
    • BARRIER系统降低线相关感染的发生率
    • US20090157000A1
    • 2009-06-18
    • US12334056
    • 2008-12-12
    • Stephen Waller
    • Stephen Waller
    • A61M5/32A61M5/44
    • A61M25/02A61M5/1418A61M5/158A61M39/0247A61M2025/024A61M2025/0253A61M2039/0261A61M2039/0273A61M2039/0285A61M2039/0294A61M2039/0297
    • A barrier system is provided for use in reducing infections associated with a percutaneous medical device, such as a catheter, that is disposed within a percutaneous incision. Such a barrier system can include: a barrier device having a skin-contacting surface and a catheter-receiving surface; and an adhesive composition configured for adhering to skin, the barrier device, and/or the catheter so as to form a barrier at or adjacent to an incision in the skin where the catheter is percutaneously inserted through the skin. The barrier device can include a conduit configured to receive the catheter. Alternatively, the barrier device can include a groove in a base surface that is configured to receive the catheter. A system that includes a medical device, the barrier device, and adhesive can also be provided.
    • 提供了一种用于减少与经皮切口中设置的经皮医疗装置(例如导管)相关联的感染的屏障系统。 这样的屏障系统可以包括:具有皮肤接触表面和导管接收表面的屏障装置; 以及粘合剂组合物,其被配置为粘附到皮肤,所述阻挡装置和/或所述导管,以在所述皮肤中的切口处或邻近的位置处形成屏障,其中所述导管经皮肤插入穿过所述皮肤。 阻挡装置可以包括构造成接收导管的导管。 或者,阻挡装置可以包括构造成接收导管的基部表面中的凹槽。 还可以提供包括医疗装置,屏障装置和粘合剂的系统。
    • 10. 发明授权
    • Network adapter validation
    • 网络适​​配器验证
    • US08307072B1
    • 2012-11-06
    • US12709676
    • 2010-02-22
    • Stephen Waller Melvin
    • Stephen Waller Melvin
    • G06F15/173
    • H04L63/10H04L29/12028H04L29/12226H04L29/12367H04L29/12839H04L61/103H04L61/2015H04L61/2514H04L61/6022H04L63/0442H04L63/162
    • The ability to validate the identity of a specific machine connected to a computerized network is provided. This involves validating MAC addresses, or any other form of digital identification that should be uniquely associated with a computer or user. This take places through the use of an identification registrar and an identification valuator. Such an identification validation system can be used with MAC addresses and can be used in conjunction with a system that records other information necessary to associate activity on a computer network with the validated MAC address. In this way, the specific computer or user associated with network activity can be determined, and it can be guaranteed that the identification has not been tampered with.
    • 提供了验证连接到计算机化网络的特定机器的身份的能力。 这涉及验证MAC地址或任何其他形式的数字标识,应与计算机或用户唯一相关联。 这通过使用识别注册商和身份评估者来进行。 这样的识别验证系统可以与MAC地址一起使用,并且可以与记录用于将计算机网络上的活动与验证的MAC地址相关联的其他信息的系统结合使用。 以这种方式,可以确定与网络活动相关联的特定计算机或用户,并且可以保证该识别尚未被篡改。