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1. 发明申请

US20110201100A1 SINGLE USE CELL CULTURE BIOREACTOR MANIFOLD SYSTEM 审中-公开
标题翻译：一次性使用细胞培养生物反应器分析系统
公开(公告)号：US20110201100A1
公开(公告)日：2011-08-18
申请号：US13009470
申请日：2011-01-19
申请人： Stephen P. Proulx , James E. Kelly, JR. , Adriane Harrington , Joeseph William Muldoon
发明人： Stephen P. Proulx , James E. Kelly, JR. , Adriane Harrington , Joeseph William Muldoon
IPC分类号： C12M1/34 , C12M1/00 , C12M1/02
CPC分类号： C12M23/44 , B01F5/106 , C12M23/00 , C12M23/28 , C12M23/40
摘要： The invention provides a disposable cell culture bioreactor manifold system for use in coupling sensors, fluid samplers, conduits, and the like, to a cell culture bioreactor in a sterile manner. The disposable bioreactor manifold system includes an externally attachable bioreactor manifold connector body for fluidly attaching modular sensor arrangements that measure physical variables and other parameters of medium contained within a bioreactor, as well as medium sampling components, and other connections, as well as at least one conduit fluidly connecting connecting the bioreactor manifold connector body with a pump for pumping fluids between the bioreactor and the bioreactor manifold connector body.
摘要翻译：本发明提供了一种用于将传感器，流体取样器，管道等耦合到细胞培养生物反应器中的无菌方式的一次性细胞培养生物反应器歧管系统。一次性生物反应器歧管系统包括可外部附接的生物反应器歧管连接器主体，用于流体连接模块化传感器装置，其测量物理变量和包含在生物反应器内的介质的其它参数，以及中等采样部件和其它连接，以及至少一个将生物反应器歧管连接器主体与用于在生物反应器和生物反应器歧管连接器主体之间泵送流体的泵流体连接的导管。

2. 发明申请

US20080284163A1 Connector for flexible tubing 审中-公开
标题翻译：软管接头
公开(公告)号：US20080284163A1
公开(公告)日：2008-11-20
申请号：US12082370
申请日：2008-04-10
申请人： Stephen P. Proulx , Joseph Cianciolo , Brian Pereira , James Vigna
发明人： Stephen P. Proulx , Joseph Cianciolo , Brian Pereira , James Vigna
IPC分类号： F16L33/00
CPC分类号： F16L37/0987 , A61M39/12 , A61M2039/1027 , F16L33/22 , F16L2201/60 , Y10T24/14
摘要： A connector is provided for connecting a flexible conduit with a second conduit having a barbed outer surface. The connector accommodates the end of the flexible conduit and the end of the second conduit in a manner which prevents removal of the flexible conduit and the second conduit from the connector. Optionally, the connector has a ring that may be used to apply additional pressure and security to the outer surface of the flexible conduit. additionally, the connector may have a wireless enabled communication and optionally, memory device such as a RFID tag attached or affixed to it.
摘要翻译：提供连接器用于将柔性导管与具有带倒钩的外表面的第二导管连接。连接器以防止柔性导管和第二导管从连接器移除的方式容纳柔性导管的端部和第二导管的端部。可选地，连接器具有可用于向柔性导管的外表面施加附加压力和安全性的环。此外，连接器可以具有无线使能通信，并且可选地，可以附接或附加到其上的诸如RFID标签的存储设备。

3. 发明授权

US07293477B2 Disposable, pre-sterilized fluid receptacle sampling device 有权
标题翻译：一次性，预先灭菌的流体容器取样装置
公开(公告)号：US07293477B2
公开(公告)日：2007-11-13
申请号：US10746030
申请日：2003-12-23
申请人： James F. Furey , Stephen P. Proulx
发明人： James F. Furey , Stephen P. Proulx
IPC分类号： G01N1/00
CPC分类号： G01N1/10 , C12M33/00 , C12M37/00 , G01N1/18 , G01N1/26 , G01N2001/1056 , G01N2001/205
摘要： The present invention provides a fluid sampling device comprising a port insert, a plurality of flexible conduits, and a plurality of sample containers. The port insert comprises a body having a plurality of shafts therethrough and sample gating means for individually opening and closing any of said shafts to enable the flow of fluid therethrough. The flexible conduits (e.g., flexible tubing) are equal in number to the elongate member, with each flexible conduit connected to or otherwise in fluid communication with an individual shaft. Similarly, the sample containers (e.g., flexible bags) are equal in number to the conduits, with each sample container connected to an individual conduit opposite the connection to the shaft. A specific configuration for the port insert, as well as kit containing sterilized components of the fluid sampling device, are also described.
摘要翻译：本发明提供一种流体采样装置，其包括端口插入件，多个柔性导管和多个样品容器。端口插入件包括具有多个轴的主体和用于单独打开和关闭任何所述轴的样品门控装置，以使流体能够流过其中。柔性管道（例如，柔性管道）的数量与细长构件的数量相等，其中每个柔性导管连接到单独的轴或与其独立地流体连通。类似地，样品容器（例如，柔性袋）的数量等于导管，每个样品容器连接到与轴的连接相对的单个导管。还描述了用于端口插入件的具体配置，以及包含流体取样装置的灭菌部件的套件。

4. 发明授权

US06863250B2 Disposable filter floor stand 有权
标题翻译：一次性过滤器底架
公开(公告)号：US06863250B2
公开(公告)日：2005-03-08
申请号：US10741910
申请日：2003-12-19
申请人： Curtis Nauseda , Stephen P. Proulx , Kevin G. McInerney , Joseph M. Almasian , Chau Nguyen , Jeremy C. Perreault
发明人： Curtis Nauseda , Stephen P. Proulx , Kevin G. McInerney , Joseph M. Almasian , Chau Nguyen , Jeremy C. Perreault
IPC分类号： B01D46/42 , B01D53/86 , F16M11/00 , A47G23/02
CPC分类号： B01D46/2411 , B01D46/0005 , B01D53/86 , B01D2265/06 , F16M11/16 , F16M11/22
摘要： The present invention relates to a stand for holding disposable filter capsules and is formed of three or more legs, a base above the legs and to which the leg as are attached and three or more arms that are attached to an opposite surface of the base from that of the legs. The arms and legs have at least curved or angled portion that allows for the arms and legs to spread out from the diameter of the base. Preferably, the arms have a second curved or angled portion that then allows the upper portion of the arms to become substantially vertical.
摘要翻译：本发明涉及一种用于保持一次性过滤胶囊的支架，并且由三根或更多支脚形成，一根底部位于腿部之上，并且该腿部与之相连，三个或更多个臂连接到基座的相对表面腿的那个。臂和腿具有至少弯曲或成角度的部分，其允许臂和腿从基部的直径扩展。优选地，臂具有第二弯曲或成角度的部分，然后允许臂的上部基本垂直。

5. 发明申请

US20080257813A1 Cassette-style filtration apparatus 审中-公开
标题翻译：盒式过滤装置
公开(公告)号：US20080257813A1
公开(公告)日：2008-10-23
申请号：US12075210
申请日：2008-03-10
申请人： Stephen P. Proulx , David DeCoste , Joseph William Muldoon
发明人： Stephen P. Proulx , David DeCoste , Joseph William Muldoon
IPC分类号： B01D25/00 , B01D63/08
CPC分类号： B01D25/26 , B01D63/081 , B01D63/084 , B01D2313/02 , B01D2313/04
摘要： A filtration apparatus is provided wherein a filtration membrane is positioned by gaskets on feed plates and filtrate plates rather than being bonded thereto.
摘要翻译：提供了一种过滤装置，其中过滤膜通过垫圈定位在进料板和滤板上而不是粘合到其上。

6. 发明授权

US08549935B2 Disposable, pre-sterilized fluid receptacle sampling device 有权
公开(公告)号：US08549935B2
公开(公告)日：2013-10-08
申请号：US12284666
申请日：2008-09-24
申请人： James F. Furey , Stephen P. Proulx
发明人： James F. Furey , Stephen P. Proulx
IPC分类号： G01N1/10
CPC分类号： G01N1/10 , C12M33/00 , C12M37/00 , G01N1/18 , G01N1/26 , G01N2001/1056 , G01N2001/205
摘要： The present invention provides a fluid sampling device comprising a port insert, a plurality of flexible conduits, and a plurality of sample containers. The port insert comprises a body having a plurality of shafts therethrough and a rotatably displaceable member for individually opening and closing any of said shafts to enable the flow of fluid therethrough. Flexible conduits (e.g., flexible tubing) are equal in number to the shafts, with each flexible conduit connected to or otherwise in fluid communication with an individual shaft. Similarly, sample containers (e.g., flexible bags) are equal in number to the conduits, with each sample container connected to an individual conduit opposite the connection to the shaft. A specific configuration for the port insert, as well as kit containing sterilized components of the fluid sampling device, are also described.

7. 发明授权

US08297661B2 Connector for flexible tubing 有权
标题翻译：软管接头
公开(公告)号：US08297661B2
公开(公告)日：2012-10-30
申请号：US12387912
申请日：2009-05-08
申请人： Stephen P. Proulx , Joseph Cianciolo , Brian Pereira , James Vigna
发明人： Stephen P. Proulx , Joseph Cianciolo , Brian Pereira , James Vigna
IPC分类号： F16L33/00
CPC分类号： F16L33/22 , A61M39/1011 , F16L37/0987 , F16L2201/60 , Y10T29/49913 , Y10T403/1624 , Y10T403/75
摘要： A connector is provided for connecting a flexible conduit with a second conduit having a barbed outer surface. The connector accommodates the end of the flexible conduit and the end of the second conduit in a manner which prevents removal of the flexible conduit and the second conduit from the connector. Optionally, the connector has a ring that may be used to apply additional pressure and security to the outer surface of the flexible conduit. additionally, the connector may have a wireless enabled communication and optionally, memory device such as a RFID tag attached or affixed to it.
摘要翻译：提供连接器用于将柔性导管与具有带倒钩的外表面的第二导管连接。连接器以防止柔性导管和第二导管从连接器移除的方式容纳柔性导管的端部和第二导管的端部。可选地，连接器具有可用于向柔性导管的外表面施加附加压力和安全性的环。此外，连接器可以具有无线使能通信，并且可选地，可以附接或附加到其上的诸如RFID标签的存储设备。

8. 发明申请

US20100326212A1 Disposable, pre-sterilized fluid receptacle sampling device 有权
标题翻译：一次性，预先灭菌的流体容器取样装置
公开(公告)号：US20100326212A1
公开(公告)日：2010-12-30
申请号：US12872436
申请日：2010-08-31
申请人： James F. Furey , Stephen P. Proulx
发明人： James F. Furey , Stephen P. Proulx
IPC分类号： G01N1/16
CPC分类号： G01N1/10 , C12M33/00 , C12M37/00 , G01N1/18 , G01N1/26 , G01N2001/1056 , G01N2001/205
摘要： The present invention provides a fluid sampling device comprising a port insert, a plurality of flexible conduits, and a plurality of sample containers. The port insert comprises a body having a plurality of shafts therethrough and a rotatably displaceable member for individually opening and closing any of said shafts to enable the flow of fluid therethrough. Flexible conduits (e.g., flexible tubing) are equal in number to the shafts, with each flexible conduit connected to or otherwise in fluid communication with an individual shaft. Similarly, sample containers (e.g., flexible bags) are equal in number to the conduits, with each sample container connected to an individual conduit opposite the connection to the shaft. A specific configuration for the port insert, as well as kit containing sterilized components of the fluid sampling device, are also described.
摘要翻译：本发明提供一种流体采样装置，其包括端口插入件，多个柔性导管和多个样品容器。端口插入件包括具有多个轴的主体和可旋转可移动的构件，用于单独地打开和关闭任何所述轴以使流体流过其中。柔性管道（例如，柔性管道）的数量与轴相等，其中每个柔性管道连接到单独的轴或以其它方式与单个轴流体连通。类似地，样品容器（例如，柔性袋）的数量与管道相等，每个样品容器连接到与与轴的连接相对的单个导管。还描述了用于端口插入件的具体配置，以及包含流体取样装置的灭菌部件的套件。

9. 发明授权

US07293475B2 Disposable, pre-sterilized fluid receptacle sampling device 有权
标题翻译：一次性，预先灭菌的流体容器取样装置
公开(公告)号：US07293475B2
公开(公告)日：2007-11-13
申请号：US11415264
申请日：2006-05-01
申请人： James F. Furey , Stephen P. Proulx
发明人： James F. Furey , Stephen P. Proulx
IPC分类号： G01N1/00
CPC分类号： G01N1/10 , C12M33/00 , C12M37/00 , G01N1/18 , G01N1/26 , G01N2001/1056 , G01N2001/205
摘要： The present invention provides a fluid sampling device comprising a port insert, a plurality of flexible conduits, and a plurality of sample containers. The port insert comprises a body having a plurality of shafts therethrough and a rotatably displaceable member for individually opening and closing any of said shafts to enable the flow of fluid therethrough. Flexible conduits (e.g., flexible tubing) are equal in number to the shafts, with each flexible conduit connected to or otherwise in fluid communication with an individual shaft. Similarly, sample containers (e.g., flexible bags) are equal in number to the conduits, with each sample container connected to an individual conduit opposite the connection to the shaft. A specific configuration for the port insert, as well as kit containing sterilized components of the fluid sampling device, are also described.
摘要翻译：本发明提供一种流体采样装置，其包括端口插入件，多个柔性导管和多个样品容器。端口插入件包括具有多个轴的主体和可旋转可移动的构件，用于单独地打开和关闭任何所述轴以使流体流过其中。柔性管道（例如，柔性管道）的数量与轴相等，其中每个柔性管道连接到单独的轴或以其它方式与单个轴流体连通。类似地，样品容器（例如，柔性袋）的数量与管道相等，每个样品容器连接到与与轴的连接相对的单个导管。还描述了用于端口插入件的具体配置，以及包含流体取样装置的灭菌部件的套件。

10. 发明授权

US08646342B2 Disposable, pre-sterilized fluid receptacle sampling device 有权
标题翻译：一次性，预先灭菌的流体容器取样装置
公开(公告)号：US08646342B2
公开(公告)日：2014-02-11
申请号：US12872436
申请日：2010-08-31
申请人： James F. Furey , Stephen P. Proulx
发明人： James F. Furey , Stephen P. Proulx
IPC分类号： G01N1/00
CPC分类号： G01N1/10 , C12M33/00 , C12M37/00 , G01N1/18 , G01N1/26 , G01N2001/1056 , G01N2001/205
摘要： The present invention provides a fluid sampling device comprising a port insert, a plurality of flexible conduits, and a plurality of sample containers. The port insert comprises a body having a plurality of shafts therethrough and a rotatably displaceable member for individually opening and closing any of said shafts to enable the flow of fluid therethrough. Flexible conduits (e.g., flexible tubing) are equal in number to the shafts, with each flexible conduit connected to or otherwise in fluid communication with an individual shaft. Similarly, sample containers (e.g., flexible bags) are equal in number to the conduits, with each sample container connected to an individual conduit opposite the connection to the shaft. A specific configuration for the port insert, as well as kit containing sterilized components of the fluid sampling device, are also described.
摘要翻译：本发明提供一种流体采样装置，其包括端口插入件，多个柔性导管和多个样品容器。端口插入件包括具有多个轴的主体和可旋转可移动的构件，用于单独地打开和关闭任何所述轴以使流体流过其中。柔性管道（例如，柔性管道）的数量与轴相等，其中每个柔性管道连接到单独的轴或以其它方式与单个轴流体连通。类似地，样品容器（例如，柔性袋）的数量与管道相等，每个样品容器连接到与与轴的连接相对的单个导管。还描述了用于端口插入件的具体配置，以及包含流体取样装置的灭菌部件的套件。

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