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1. 发明申请

US20050019421A1 Disinfecting compositions and methods of making and using same 审中-公开
标题翻译：消毒组合物及其制备和使用方法
公开(公告)号：US20050019421A1
公开(公告)日：2005-01-27
申请号：US10625271
申请日：2003-07-23
申请人： Terry Hobbs , Jeffrey Andrews , Sophia Czechowicz , Luke Schallinger
发明人： Terry Hobbs , Jeffrey Andrews , Sophia Czechowicz , Luke Schallinger
IPC分类号： A61L2/18 , A61L2/22 , C11D3/20 , C11D3/39 , A61K33/40 , A61K31/19
CPC分类号： A61L2/186 , A61L2/22 , A61L2202/24 , A61L2202/26 , C11D3/2075 , C11D3/3947
摘要： The present invention provides a composition, comprising: greater than about 0.1% by weight hydrogen peroxide; an aromatic acid component; surfactant; optionally, a solvent; and a carrier. The composition of the invention is useful as a disinfecting composition for killing microorganisms such as bacterium (including Mycobacterium), spores and fungi. The composition provides a pathogenic bacteria kill rate of 99.9% in about 30 seconds when bacteria are exposed to the composition and is effective in providing a Mycobacterium kill of 106 with two minutes or less. Moreover, the compositions of the invention are generally more resistant to catalase deactivation than, for example, an aqueous solution of hydrogen peroxide. The concentration of hydrogen peroxide within the composition may range from about 1% by weight to about 7% by weight and the concentration of aromatic acid component may range from about 0.1% by weight to about 5% by weight. The invention also provides a method for disinfection of a substrate utilizing the composition. The composition of the invention may be used in the foregoing method on a medical instrument, such as an endoscope or the like. Applying the compositions to a substrate may be accomplished in any of a variety of application methods such as by roll coating, dipping, spraying, or rotational tumbling. The composition may be applied to the substrate for a period of time ranging from about 30 seconds to about ten minutes. In this aspect, the invention can further comprise drying the substrate after removing the composition.
摘要翻译：本发明提供一种组合物，其包含：大于约0.1重量％的过氧化氢; 芳香族酸成分; 表面活性剂任选地，溶剂; 和载体。本发明的组合物可用作杀灭细菌（包括分枝杆菌），孢子和真菌等微生物的消毒组合物。当细菌暴露于组合物时，组合物在约30秒内提供99.9％的病原菌杀灭率，并有效地在两分钟或更短时间内提供10 6的分枝杆菌杀死。此外，本发明的组合物通常比例如过氧化氢水溶液更能抵抗过氧化氢酶失活。组合物中过氧化氢的浓度可以为约1重量％至约7重量％，芳族酸组分的浓度可以为约0.1重量％至约5重量％。本发明还提供了利用该组合物消毒底物的方法。本发明的组合物可以在上述方法中用于诸如内窥镜等的医疗器械上。将组合物施用于基材可以通过各种施用方法中的任何一种来实现，例如通过辊涂，浸涂，喷涂或旋转翻滚。组合物可以施加到基材上约30秒至约十分钟的时间。在这方面，本发明还可以包括在去除组合物之后干燥基材。

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