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    • 1. 发明申请
    • Population pharmacokinetic modeling and analysis (PDX-POP™)
    • 群体药动学模型和分析(PDX-POP(TM))
    • US20060161408A1
    • 2006-07-20
    • US11375753
    • 2006-03-15
    • William BachmanSian BigoraMarc GastonguayDavid Young
    • William BachmanSian BigoraMarc GastonguayDavid Young
    • G06G7/48G06G7/58
    • G16C20/30G16B5/00G16B50/00
    • A biological modeling system and method for enhanced computer-aided analysis of biological response data provides information synthesized from multiple sources. An executable model of a biological system is developed from information and structures based on multiple sources. In a preferred embodiment, biological data sets are selected by a user from a first active viewer window on a user computer display. A model is created and then run using integrated pharmacokinetic software. The output is next analyzed using integrated analysis tools. Once analyzed, the model is balanced to ensure that it matches the information and structures. Once the model is created, run, and balanced, it can be used to draw attention to important relations through integrated reporting functions. This program could be run with such programs as NONMEM®.
    • 用于增强生物反应数据计算机辅助分析的生物建模系统和方法提供从多个来源合成的信息。 基于多个来源的信息和结构开发了生物系统的可执行模型。 在优选实施例中,用户从用户计算机显示器上的第一活动查看器窗口选择生物数据集。 创建一个模型,然后使用集成的药代动力学软件运行。 接下来使用集成分析工具对输出进行分析。 一旦分析,模型是平衡的,以确保它与信息和结构匹配。 一旦模型创建,运行和平衡,它可以用于通过集成报告功能来引起对重要关系的关注。 该程序可以使用诸如NONMEM(R)这样的程序来运行。