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    • 1. 发明申请
    • Biosensors
    • US20050247573A1
    • 2005-11-10
    • US11087015
    • 2005-03-22
    • Hideaki NakamuraShouji ShinoharaMasao GotohIsao Karube
    • Hideaki NakamuraShouji ShinoharaMasao GotohIsao Karube
    • G01N27/26G01N33/487
    • G01N27/3272
    • The biosensors of the present invention comprise an electrically insulating substrate, an electrically insulating cover connected to the substrate via a spacer layer, a reaction-detecting section formed on the substrate at a region sandwiched between the substrate and cover, and comprising at least one set of electrodes, and an external terminal to be connected to the reaction-detecting section, and a sealed sample-feeding path defined between the substrate and cover by the spacer layer, where the sample-feeding path has a portion intersecting the electrodes, as well as a cutting plane line provided at an outermost surface of the substrate or cover, which is a boundary between a sensor portion comprising electrodes and a sealed cap portion which does not comprise electrodes, and the cutting plane line is present at a position where, when the sealed cap portion is cut along the cutting plane line, the cut surface does not cross the electrodes and does cross the sample-feeding path, so that a sample-inlet port and an air-discharge port leading from the sample-feeding path are exposed through the cut surface. In addition, the biosensors for simultaneously measuring multiple items of the present invention comprise: a substrate; a cover connected to the substrate via a spacer layer; and a number of biosensor units comprising substrates each containing at least one biosensor unit which comprises a reaction-detecting section including one electrode system and one reagent layer on the substrate, and a sample-feeding path including the reagent layer, wherein each of the biosensor units comprise one reagent layer on one sample-feeding path, a cutting plane line for dividing each of the biosensor unit-comprising substrates is provided at a top surface of the substrate or cover, the cutting plane line and sample-feeding path are placed such that, when the substrate or cover is cut along the cutting plane line, a sample-inlet port for supplying a sample solution is open to a cut surface of each biosensor unit-comprising substrate as a cut port of the sample-feeding path.