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1. 发明授权

US08605266B2 Component measurement apparatus with variable focusing and satble light source output 有权
标题翻译：具有可变聚焦和饱和光源输出的分量测量装置
公开(公告)号：US08605266B2
公开(公告)日：2013-12-10
申请号：US13041097
申请日：2011-03-04
申请人： Shin-ichiro Tezuka , Hitoshi Hara
发明人： Shin-ichiro Tezuka , Hitoshi Hara
IPC分类号： G01N33/48 , G02B7/04
CPC分类号： G01N21/4795 , A61B5/14532 , A61B5/1455 , A61B2562/0242 , G01N21/359 , G01N2201/0612
摘要： A component measurement apparatus includes a confocal optical system including a laser emitting laser light, a collimating lens collimating the laser light emitted from the laser, an objective lens condensing the collimated light having exited the collimating lens in order to illuminate internal tissue of an object of measurement, a half mirror redirecting reflected light reflected by the internal tissue of the object of measurement and refracted by the objective lens, a pin hole through which the reflected light redirected by the half mirror passes, and a light-receiving element receiving the reflected light having passed through the pin hole. The component measurement apparatus also includes a data analyzer section measuring a component of the object of measurement in accordance with data output from the light-receiving element. In the component measurement the apparatus, a focal position of the objective lens is adjustable along an optical axis.
摘要翻译：分量测量装置包括共焦光学系统，其包括激光发射激光，准直透镜，准直激光从激光发射的激光;物镜，会聚已退出准直透镜的准直光，以照亮物体的内部组织测量半反射镜重定向由被测物体的内部组织反射并被物镜折射的反射光，由半反射镜重定向的反射光穿过的针孔通过;以及接收反射光的光接收元件已经穿过针孔。部件测量装置还包括根据从光接收元件输出的数据测量测量对象的分量的数据分析器部分。在该装置的部件测量中，物镜的焦点位置可沿光轴调节。

2. 发明申请

US20110218412A1 LIVING-BODY COMPONENT MEASURING APPARATUS 有权
标题翻译：生命体部件测量装置
公开(公告)号：US20110218412A1
公开(公告)日：2011-09-08
申请号：US13041105
申请日：2011-03-04
申请人： Shin-ichiro Tezuka , Hitoshi Hara
发明人： Shin-ichiro Tezuka , Hitoshi Hara
IPC分类号： A61B5/1455
CPC分类号： A61B5/1455 , A61B5/14532 , A61B2562/0242 , G01N21/49
摘要： A living-body component measuring apparatus measures a component of an inner tissue of a living body serving as an object to be measured by emitting laser light having two or more wavelengths from a light source and measuring reflected light of the laser light from the inner tissue of the living body. The living-body component measuring apparatus includes a beam splitter that changes optical paths of a part of the laser light and the reflected light, a reference-light measuring unit that measures, as reference light, the part of the laser light having the optical path changed by the beam splitter, a reflected-light measuring unit that measures the reflected light having the optical path changed by the beam splitter, and an analysis unit that analyzes the inner tissue by measuring a spectrum of the reflected light or the reference light.
摘要翻译：生物体成分测量装置通过从光源发射具有两个或更多个波长的激光并测量来自内部组织的激光的反射光来测量用作待测物体的生物体的内部组织的成分的生物体。生物体成分测量装置包括：分束器，其改变激光的一部分和反射光的光路;参考光测量单元，其测量具有光路的激光的一部分作为参考光; 由分束器改变的反射光测量单元，其测量具有由分束器改变的光路的反射光;以及分析单元，其通过测量反射光或参考光的光谱来分析内部组织。

3. 发明授权

US08547535B2 Component measurement apparatus 有权
标题翻译：元件测量装置
公开(公告)号：US08547535B2
公开(公告)日：2013-10-01
申请号：US13040872
申请日：2011-03-04
申请人： Shin-ichiro Tezuka , Hitoshi Hara
发明人： Shin-ichiro Tezuka , Hitoshi Hara
IPC分类号： G01N33/48 , G02B7/04
CPC分类号： G01N21/49 , A61B5/14532 , A61B5/1455 , G01N21/359
摘要： A component measurement apparatus includes a laser that emits non-collimated laser light, an objective lens that condenses the non-collimated laser light emitted from the laser in order for the laser light to illuminate internal tissue of an object of measurement without collimating the laser light, a half mirror that redirects reflected light reflected by the internal tissue of the object of measurement and refracted by the objective lens, a pin hole through which the reflected light redirected by the half mirror passes, a light-receiving element that receives the reflected light having passed through a pin hole, and a data analyzer section that measures a component of the object of measurement in accordance with data output from the light-receiving element.
摘要翻译：元件测量装置包括发射非准直激光的激光器，冷凝从激光器发射的非准直激光的物镜，以使激光照亮测量对象的内部组织而不使激光器将由被测物体的内部组织反射的被物镜折射的反射光重定向的半反射镜，由半反射镜重定向的反射光穿过的针孔通过接受反射光的光接收元件已经通过针孔的数据分析器部分，以及根据从光接收元件输出的数据来测量测量对象的分量的数据分析器部分。

4. 发明申请

US20120013896A1 INSTRUMENT FOR MEASURING BIOGENIC SUBSTANCE, USING CONFOCAL OPTICAL SYSTEM 审中-公开
标题翻译：用于测量生物物质的仪器，使用共焦光学系统
公开(公告)号：US20120013896A1
公开(公告)日：2012-01-19
申请号：US13184217
申请日：2011-07-15
申请人： Shin-ichiro TEZUKA , Hitoshi HARA
发明人： Shin-ichiro TEZUKA , Hitoshi HARA
IPC分类号： G01J1/40
CPC分类号： G01N21/474 , A61B5/14532 , A61B5/1455 , A61B5/1491 , A61B2560/0242 , G01N21/49 , G01N2201/0221
摘要： An instrument for measuring a biogenic substance, using the confocal optical system that is simplified and reducing measurement error caused by the difference in physical condition or temperature due to weather of the season is realized. The instrument for measuring a biogenic substance, using the confocal optical system comprises the confocal optical system comprised of a laser source, a lens system for collimating light from the laser source, a half mirror for causing the light collimated by the lens system to be transmitted therethrough, a lens system for converging the light that is transmitted through the half mirror, a lens system, a pinhole and a photodetector, and a body for housing these elements and provided with a run button and an exit aperture.
摘要翻译：实现了一种用于测量生物源物质的仪器，使用简化的共聚焦光学系统，并减少由于季节天气导致的身体状况或温度差异引起的测量误差。使用共焦光学系统的用于测量生物源物质的仪器包括由激光源组成的共焦光学系统，用于准直来自激光源的光的透镜系统，用于使由透镜系统准直的光被透射的半反射镜通过其透镜系统，用于会聚透过半反射镜的光，透镜系统，针孔和光电检测器，以及用于容纳这些元件的本体，并具有行程按钮和出口孔。

5. 发明申请

US20110216308A1 COMPONENT MEASUREMENT APPARATUS 有权
标题翻译：组件测量装置
公开(公告)号：US20110216308A1
公开(公告)日：2011-09-08
申请号：US13040872
申请日：2011-03-04
申请人： Shin-ichiro Tezuka , Hitoshi Hara
发明人： Shin-ichiro Tezuka , Hitoshi Hara
IPC分类号： G01N33/48 , G01N21/55
CPC分类号： G01N21/49 , A61B5/14532 , A61B5/1455 , G01N21/359
摘要： A component measurement apparatus includes a laser that emits non-collimated laser light, an objective lens that condenses the non-collimated laser light emitted from the laser in order for the laser light to illuminate internal tissue of an object of measurement without collimating the laser light, a half mirror that redirects reflected light reflected by the internal tissue of the object of measurement and refracted by the objective lens, a pin hole through which the reflected light redirected by the half mirror passes, a light-receiving element that receives the reflected light having passed through a pin hole, and a data analyzer section that measures a component of the object of measurement in accordance with data output from the light-receiving element.
摘要翻译：元件测量装置包括发射非准直激光的激光器，冷凝从激光器发射的非准直激光的物镜，以使激光照亮测量对象的内部组织而不使激光器将由被测物体的内部组织反射的被物镜折射的反射光重定向的半反射镜，由半反射镜重定向的反射光穿过的针孔通过接受反射光的光接收元件已经通过针孔的数据分析器部分，以及根据从光接收元件输出的数据来测量测量对象的分量的数据分析器部分。

6. 发明申请

US20120016214A1 CALIBRATION METHOD FOR CALIBRATING AN INSTRUMENT FOR MEASURING BIOGENIC SUBSTANCE, USING NEAR-INFRARED SPECTRAL SPECTROSCOPY 有权
标题翻译：用于校准用于测量生物物质的仪器的校准方法，使用近红外光谱分析
公开(公告)号：US20120016214A1
公开(公告)日：2012-01-19
申请号：US13184259
申请日：2011-07-15
申请人： Shin-ichiro TEZUKA , Hitoshi HARA
发明人： Shin-ichiro TEZUKA , Hitoshi HARA
IPC分类号： A61B5/1455
CPC分类号： G01N21/274 , A61B5/1455 , A61B2560/0223 , G01N21/359
摘要： A simple calibration method for calibrating an instrument for measuring a biogenic substance, using near-infrared spectral spectroscopy is realized. The calibration method comprises (1) the step of measuring a specific substance of a biological object with the use of an instrument for measuring a biogenic substance, using a confocal optical system, (2) the step of using an instrument for measuring a biogenic substance, using near-infrared spectral spectroscopy, thereby measuring a specific substance in the same region of the biological object, (3) the step of comparing a measured value of the specific substance, measured in the step (1) with a measured value of the specific substance, measured in the step, and (4) the step of executing an operation in the step at least once after the elapse of predetermined time.
摘要翻译：实现了使用近红外光谱法校准用于测量生物物质的仪器的简单校准方法。校准方法包括：（1）使用共聚焦光学系统测量生物物质的仪器，测量生物体的特定物质的步骤，（2）使用用于测量生物物质的仪器的步骤，使用近红外光谱，从而测定生物体的相同区域中的特定物质，（3）将步骤（1）中测定的特定物质的测定值与在步骤中测量的特定物质，和（4）在经过预定时间之后至少执行一次该步骤中的操作的步骤。

7. 发明授权

US08880136B2 Calibration method for calibrating an instrument for measuring biogenic substance, using near-infrared spectral spectroscopy 有权
标题翻译：使用近红外光谱法校准用于测量生物物质的仪器的校准方法
公开(公告)号：US08880136B2
公开(公告)日：2014-11-04
申请号：US13184259
申请日：2011-07-15
申请人： Shin-ichiro Tezuka , Hitoshi Hara
发明人： Shin-ichiro Tezuka , Hitoshi Hara
IPC分类号： A61B5/1455 , G01N21/35 , G01N21/27
CPC分类号： G01N21/274 , A61B5/1455 , A61B2560/0223 , G01N21/359
摘要： A simple calibration method for calibrating an instrument for measuring a biogenic substance, using near-infrared spectral spectroscopy is realized. The calibration method comprises (1) the step of measuring a specific substance of a biological object with the use of an instrument for measuring a biogenic substance, using a confocal optical system, (2) the step of using an instrument for measuring a biogenic substance, using near-infrared spectral spectroscopy, thereby measuring a specific substance in the same region of the biological object, (3) the step of comparing a measured value of the specific substance, measured in the step (1) with a measured value of the specific substance, measured in the step, and (4) the step of executing an operation in the step at least once after the elapse of predetermined time.
摘要翻译：实现了使用近红外光谱法校准用于测量生物物质的仪器的简单校准方法。校准方法包括：（1）使用共聚焦光学系统测量生物物质的仪器测量生物体的特定物质的步骤，（2）使用用于测量生物物质的仪器的步骤，使用近红外光谱，从而测定生物体的相同区域中的特定物质，（3）将步骤（1）中测定的特定物质的测定值与在步骤中测量的特定物质，和（4）在经过预定时间之后至少执行一次该步骤中的操作的步骤。

8. 发明授权

US08958858B2 Living-body component measuring apparatus 有权
标题翻译：生物体成分测量装置
公开(公告)号：US08958858B2
公开(公告)日：2015-02-17
申请号：US13041105
申请日：2011-03-04
申请人： Shin-ichiro Tezuka , Hitoshi Hara
发明人： Shin-ichiro Tezuka , Hitoshi Hara
IPC分类号： A61B5/1455 , A61B5/145 , G01N21/49
CPC分类号： A61B5/1455 , A61B5/14532 , A61B2562/0242 , G01N21/49
摘要： A living-body component measuring apparatus measures a component of an inner tissue of a living body serving as an object to be measured by emitting laser light having two or more wavelengths from a light source and measuring reflected light of the laser light from the inner tissue of the living body. The living-body component measuring apparatus includes a beam splitter that changes optical paths of a part of the laser light and the reflected light, a reference-light measuring unit that measures, as reference light, the part of the laser light having the optical path changed by the beam splitter, a reflected-light measuring unit that measures the reflected light having the optical path changed by the beam splitter, and an analysis unit that analyzes the inner tissue by measuring a spectrum of the reflected light or the reference light.
摘要翻译：生物体成分测量装置通过从光源发射具有两个或更多个波长的激光并测量来自内部组织的激光的反射光来测量用作待测物体的生物体的内部组织的成分的生物体。生物体成分测量装置包括：分束器，其改变激光的一部分和反射光的光路;参考光测量单元，其测量具有光路的激光的一部分作为参考光; 由分束器改变的反射光测量单元，其测量具有由分束器改变的光路的反射光;以及分析单元，其通过测量反射光或参考光的光谱来分析内部组织。

9. 发明申请

US20110216309A1 COMPONENT MEASUREMENT APPARATUS 有权
标题翻译：组件测量装置
公开(公告)号：US20110216309A1
公开(公告)日：2011-09-08
申请号：US13041097
申请日：2011-03-04
申请人： Shin-ichiro Tezuka , Hitoshi Hara
发明人： Shin-ichiro Tezuka , Hitoshi Hara
IPC分类号： G01N33/48 , G01N21/55
CPC分类号： G01N21/4795 , A61B5/14532 , A61B5/1455 , A61B2562/0242 , G01N21/359 , G01N2201/0612
摘要： A component measurement apparatus includes a confocal optical system including a laser emitting laser light, a collimating lens collimating the laser light emitted from the laser, an objective lens condensing the collimated light having exited the collimating lens in order to illuminate internal tissue of an object of measurement, a half mirror redirecting reflected light reflected by the internal tissue of the object of measurement and refracted by the objective lens, a pin hole through which the reflected light redirected by the half mirror passes, and a light-receiving element receiving the reflected light having passed through the pin hole. The component measurement apparatus also includes a data analyzer section measuring a component of the object of measurement in accordance with data output from the light-receiving element. In the component measurement the apparatus, a focal position of the objective lens is adjustable along an optical axis.
摘要翻译：分量测量装置包括共焦光学系统，其包括激光发射激光，准直透镜，准直激光从激光发射的激光;物镜，会聚已退出准直透镜的准直光，以照亮物体的内部组织测量半反射镜重定向由被测物体的内部组织反射并被物镜折射的反射光，由半反射镜重定向的反射光穿过的针孔通过;以及接收反射光的光接收元件已经穿过针孔。部件测量装置还包括根据从光接收元件输出的数据测量测量对象的分量的数据分析器部分。在该装置的部件测量中，物镜的焦点位置可沿光轴调节。

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