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1. 发明申请

US20110195850A1 COMPACT NANOFABRICATION APPARATUS 审中-公开
标题翻译：紧凑的纳米装置
公开(公告)号：US20110195850A1
公开(公告)日：2011-08-11
申请号：US13088284
申请日：2011-04-15
申请人： Sergey V. ROZHOK , Michael Nelson , Nabil A. Amro , Joseph S. Fragala , Raymond Roger Shile , John Edward Bussan , Dirk N. vanMerkestyn
发明人： Sergey V. ROZHOK , Michael Nelson , Nabil A. Amro , Joseph S. Fragala , Raymond Roger Shile , John Edward Bussan , Dirk N. vanMerkestyn
IPC分类号： C40B30/00 , C40B50/14
CPC分类号： G03F7/0002 , G01Q80/00 , G03F7/70383 , G03F9/00
摘要： An apparatus for use in fabricating structures and depositing materials from tips to surfaces for patterning in direct-write mode, providing ability to travel macroscopic distances and yet provide for nanoscale patterning. Useful in small scale fabrication and nanolithography. The instrument can be compact and used on a laboratory bench or desktop. An apparatus comprising: at least one multi-axis assembly comprising a plurality of nanopositioning stages, at least one pen assembly, wherein the pen assembly and the multi-axis assembly are adapted for delivery of material from the pen assembly to a substrate which is positioned by the multi-axis assembly, at least one viewing assembly, at least one controller. Nanopositioning by piezoelectric methods and devices and motors is particularly useful. The apparatus can include integrated environmental chambers and housings, as well as ink reservoirs for materials to be delivered. The viewing assembly can be a microscope with a long working distance. Particularly useful for fabrication of bioarrays or microarrays. The multi-axis assembly can be a five-axis assembly. Software can facilitate efficient usage.
摘要翻译：一种用于制造结构并从尖端到表面沉积材料的装置，用于以直写式模式进行图案化，提供行进宏观距离并提供纳米尺度图案化的能力。适用于小规模制造和纳米光刻。该仪器可以紧凑，并在实验台或台式机上使用。一种装置，包括：至少一个多轴组件，其包括多个纳米定位阶段，至少一个笔组件，其中所述笔组件和所述多轴组件适于将材料从所述笔组件传送到定位的衬底通过多轴组件，至少一个观察组件，至少一个控制器。通过压电方法和装置和电动机的定位是特别有用的。该设备可以包括集成的环境室和壳体，以及用于要输送的材料的油墨储存器。观察组件可以是具有长工作距离的显微镜。特别适用于制造生物芯片或微阵列。多轴组件可以是五轴组件。软件可以促进有效的使用。

2. 发明申请

US20110274839A1 Cantilevers for deposition 审中-公开
标题翻译：用于沉积的悬臂
公开(公告)号：US20110274839A1
公开(公告)日：2011-11-10
申请号：US13064766
申请日：2011-04-13
申请人： Joseph S. Fragala , R. Roger Shile , Sergey V. Rozhok
发明人： Joseph S. Fragala , R. Roger Shile , Sergey V. Rozhok
IPC分类号： B05C5/00 , B05D1/36 , C23F1/00 , B05D5/00
CPC分类号： G03F7/0002 , B81B2203/0118 , B81C1/00031 , B81C99/0025 , B82B3/00 , B82Y10/00 , B82Y40/00 , G03F7/2049
摘要： Cantilever design for patterning from a cantilever tip can be improved with, for example, a recessed area surrounding the cantilever tip. A device for printing nanoscopic and microscopic patterns includes at least one cantilever having a front surface, a first side edge, a second side edge, and a first end which is a free end and a second end which is a non-free end. The front surface includes at least one first sidewall disposed at the first cantilever side edge and at least one second sidewall disposed at the second cantilever side edge opposing the first cantilever side edge, at least one channel, adapted to hold a fluid, disposed between the first and second sidewalls, wherein the channel, the first sidewall, and the second sidewall extend toward the cantilever free end but do not reach the free end, and a base region having a boundary defined by the first edge, the second edge, and the cantilever free end and also the first sidewall, second sidewall, and the channel, wherein the base region comprises a tip extending away from the cantilever front surface. Improved deposition can result. Fluidic inks comprising biomolecules can be patterned successfully.
摘要翻译：例如可以通过围绕悬臂尖端的凹陷区域来改善从悬臂尖端进行图案化的悬臂设计。用于印刷纳米尺度和微观图案的装置包括至少一个具有前表面，第一侧边缘，第二侧边缘以及作为自由端的第一端和作为非自由端的第二端的悬臂。前表面包括设置在第一悬臂侧边缘处的至少一个第一侧壁和设置在与第一悬臂侧边缘相对的第二悬臂侧边缘处的至少一个第二侧壁，至少一个适于保持流体的通道，第一和第二侧壁，其中，所述通道，所述第一侧壁和所述第二侧壁朝向所述悬臂自由端延伸，但是不到达所述自由端，并且具有由所述第一边缘，所述第二边缘和所述第二边缘限定的边界的基底区域悬臂自由端以及第一侧壁，第二侧壁和通道，其中基部区域包括远离悬臂前表面延伸的尖端。可以改善沉积。可以成功地构图包含生物分子的流体油墨。

3. 发明申请

US20110014378A1 LEVELING DEVICES AND METHODS 审中-公开
标题翻译：水平设备和方法
公开(公告)号：US20110014378A1
公开(公告)日：2011-01-20
申请号：US12838384
申请日：2010-07-16
申请人： John Edward BUSSAN , Sergey V. Rozhok , Vadim Val-Khvalabov , Joseph S. Fragala , Jason R. Haaheim , Michael R. Nelson , Edward R. Solheim , Javad M. Vakil
发明人： John Edward BUSSAN , Sergey V. Rozhok , Vadim Val-Khvalabov , Joseph S. Fragala , Jason R. Haaheim , Michael R. Nelson , Edward R. Solheim , Javad M. Vakil
IPC分类号： B05D3/12 , G01Q70/02 , G01Q70/00 , G01Q80/00 , G01Q20/02 , F16M13/00
CPC分类号： G03F7/0002 , G01Q80/00 , G03F9/7034 , G03F9/7053
摘要： Devices for leveling an object for patterning a substrate surface, including an array of scanning probe tips, are provided. A device may include a support structure adapted to mount an object, the object having a plurality of protrusions adapted to form a pattern on a surface of a substrate upon contact of the object to the surface; and at least one flexible joint assembly mounted to the support structure and adapted to allow the object to achieve a parallel orientation with respect to the surface upon contact of the object to the surface. Also provided are apparatuses and kits incorporating the devices and methods of making and using the devices and apparatuses.
摘要翻译：提供了用于调整用于图案化衬底表面的对象的设备，包括扫描探针尖端的阵列。装置可以包括适于安装物体的支撑结构，所述物体具有适于在物体与表面接触时在基底的表面上形成图案的多个突起; 以及至少一个柔性接头组件，其安装到所述支撑结构并且适于允许所述物体在所述物体与所述表面接触时相对于所述表面实现平行取向。还提供了结合设备的装置和套件以及制造和使用设备和装置的方法。

4. 发明申请

US20120135876A1 HIGH-THROUGHPUT ASSAY METHODS AND ARTICLES 审中-公开
标题翻译：高通量测定方法和文章
公开(公告)号：US20120135876A1
公开(公告)日：2012-05-31
申请号：US13286092
申请日：2011-10-31
申请人： Sergey V. ROZHOK , Yong Jie OUYANG
发明人： Sergey V. ROZHOK , Yong Jie OUYANG
IPC分类号： C40B30/04 , C40B40/10
CPC分类号： B01L3/5088 , B01L3/50853 , B01L2200/025 , B01L2300/0819 , B01L2300/0822 , G01N1/2813
摘要： An assay device and method of use thereof, include a multiwell chip and a microarray slide printed with capture molecules. The chip contains shallow wells for holding liquid samples and, optionally, shoulders for receiving the slide. The slide, when placed on the chip, can contact the top of the liquid sample and draw the liquid sample upwards onto the capture molecules. The microarray slide and multiwell chip are capable of forming a closed incubation chamber preventing outside contamination and liquid evaporation. Patterning of the slide can be carried out by direct write lithography or nanolithography, including DPN printing. Small liquid volumes can be used.
摘要翻译：测定装置及其使用方法包括印有捕获分子的多孔芯片和微阵列载玻片。该芯片包含用于保存液体样品的浅孔，以及可选地用于接收载玻片的肩部。当放置在芯片上时，载玻片可以接触液体样品的顶部并将液体样品向上抽吸到捕获分子上。微阵列载玻片和多孔芯片能够形成封闭的孵育室，防止外部污染和液体蒸发。幻灯片的图案可以通过直接写入光刻或纳米光刻进行，包括DPN打印。可以使用小的液体体积。

5. 发明申请

US20120108461A1 HIGH-THROUGHPUT SLIDE PROCESSING APPARATUS 审中-公开
标题翻译：高强度滑块加工设备
公开(公告)号：US20120108461A1
公开(公告)日：2012-05-03
申请号：US13286078
申请日：2011-10-31
申请人： John E. Bussan , Michael R. Nelson , Pat N. Morgan , Sergey V. Rozhok , Jeff Rendlin
发明人： John E. Bussan , Michael R. Nelson , Pat N. Morgan , Sergey V. Rozhok , Jeff Rendlin
IPC分类号： C40B30/04 , G01N35/00 , C40B40/10 , G01N33/543
CPC分类号： G01N35/028 , G01N35/00029 , G01N2035/00138 , Y10T436/112499
摘要： An assay device and method of use thereof includes a sample tray comprising a plurality of sample wells having a first volume, and a slide tray comprising a slide, and a liquid dispenser. The slide comprises a plurality of reaction sites on a bottom surface of the slide. The liquid dispenser is configured to dispense a plurality of liquid samples into the sample wells. The sample wells are configured to hold the liquid samples. Each of the liquid samples has a second volume such that the second volume exceeds the first volume and each of the liquid sample sits within and above one of the sample wells. The slide tray and the sample tray are configured such that the slide tray can be placed onto the sample tray, at least one of the reaction sites can be positioned directly above at least one of the sample wells containing a liquid sample, and the liquid sample can be drawn onto the reaction site upon the liquid sample contacting the bottom surface of the slide.
摘要翻译：测定装置及其使用方法包括包含多个具有第一体积的样品孔的样品盘和包括载玻片的滑动盘和液体分配器。滑块包括滑块底表面上的多个反应位点。液体分配器配置成将多个液体样品分配到样品孔中。样品孔配置成保持液体样品。每个液体样品具有第二体积，使得第二体积超过第一体积，并且每个液体样品位于一个样品孔内和上面。滑动托盘和样品托盘被配置为使得滑动托盘可以放置在样品托盘上，至少一个反应位点可以直接位于至少一个含有液体样品的样品孔的上方，液体样品可以在液体样品接触载玻片的底表面时被吸引到反应部位上。

6. 发明申请

US20090023607A1 COMPACT NANOFABRICATION APPARATUS 审中-公开
标题翻译：紧凑的纳米装置
公开(公告)号：US20090023607A1
公开(公告)日：2009-01-22
申请号：US12116908
申请日：2008-05-07
申请人： Sergey V. Rozhok , Michael Nelson , Nabil A. Amro , Joseph S. Fragala , Raymond Roger Shile , John Edward Bussan , Dirk N. vanMerkestyn
发明人： Sergey V. Rozhok , Michael Nelson , Nabil A. Amro , Joseph S. Fragala , Raymond Roger Shile , John Edward Bussan , Dirk N. vanMerkestyn
IPC分类号： C40B50/14 , C40B60/14
CPC分类号： G03F7/0002 , G01Q80/00 , G03F7/70383 , G03F9/00
摘要： An apparatus for use in fabricating structures and depositing materials from tips to surfaces for patterning in direct-write mode, providing ability to travel macroscopic distances and yet provide for nanoscale patterning. Useful in small scale fabrication and nanolithography. The instrument can be compact and used on a laboratory bench or desktop. An apparatus comprising: at least one multi-axis assembly comprising a plurality of nanopositioning stages, at least one pen assembly, wherein the pen assembly and the multi-axis assembly are adapted for delivery of material from the pen assembly to a substrate which is positioned by the multi-axis assembly, at least one viewing assembly, at least one controller. Nanopositioning by piezoelectric methods and devices and motors is particularly useful. The apparatus can include integrated environmental chambers and housings, as well as ink reservoirs for materials to be delivered. The viewing assembly can be a microscope with a long working distance. Particularly useful for fabrication of bioarrays or microarrays. The multi-axis assembly can be a five-axis assembly. Software can facilitate efficient usage.
摘要翻译：一种用于制造结构并从尖端到表面沉积材料的装置，用于以直写式模式进行图案化，提供行进宏观距离并提供纳米尺度图案化的能力。适用于小规模制造和纳米光刻。该仪器可以紧凑，并在实验台或台式机上使用。一种装置，包括：至少一个多轴组件，其包括多个纳米定位阶段，至少一个笔组件，其中所述笔组件和所述多轴组件适于将材料从所述笔组件传送到定位的衬底通过多轴组件，至少一个观察组件，至少一个控制器。通过压电方法和装置和电动机的定位是特别有用的。该设备可以包括集成的环境室和壳体，以及用于要输送的材料的油墨储存器。观察组件可以是具有长工作距离的显微镜。特别适用于制造生物芯片或微阵列。多轴组件可以是五轴组件。软件可以促进有效的使用。

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