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1. 发明授权

US08571283B2 Method for simultaneously extracting the input function and pharmacokinetic parameters of an active ingredient 有权
标题翻译：同时提取活性成分的输入功能和药代动力学参数的方法
公开(公告)号：US08571283B2
公开(公告)日：2013-10-29
申请号：US13043969
申请日：2011-03-09
申请人： Renaud Maroy , Segolene De Gavriloff
发明人： Renaud Maroy , Segolene De Gavriloff
IPC分类号： G06K9/00
CPC分类号： G06F19/704
摘要： This extraction method in a structure of a living organism from a measurement image of the kinetics of the active ingredient comprising a plurality of regions of interest inside each of which the kinetics of the active ingredient are measured, comprises the following steps: determining (30) a plurality of sets of kinetics, the determined sets of kinetics being different from each other and each determined set of kinetics including several measured kinetics; defining (32) at least one kinetic model, parameters of the defined kinetics model being formed by the parameters of the input function and the pharmacokinetic parameters; estimating (34) the input function and the pharmacokinetic parameters by resolving the kinetic model defined from the determined set of kinetics; and deducing (36) the final input function and the final pharmacokinetic parameters.
摘要翻译：来自活性成分的活性成分的动力学的测定图像的活性成分的结构的提取方法包括测定活性成分的动力学的各个感兴趣区域，包括以下步骤：确定（30）多组动力学，确定的动力学集合彼此不同，并且每个确定的动力学集合包括几个测量的动力学; 定义（32）至少一个动力学模型，所定义的动力学模型的参数由输入函数的参数和药代动力学参数形成; 通过解决从确定的动力学集合定义的动力学模型来估计（34）输入函数和药代动力学参数; 并推导（36）最终输入函数和最终药代动力学参数。

2. 发明申请

US20110229000A1 METHOD FOR SIMULTANEOUSLY EXTRACTING THE INPUT FUNCTION AND PHARMACOKINETIC PARAMETERS OF AN ACTIVE INGREDIENT 有权
标题翻译：同时提取活性成分的输入功能和药代动力学参数的方法
公开(公告)号：US20110229000A1
公开(公告)日：2011-09-22
申请号：US13043969
申请日：2011-03-09
申请人： Renaud MAROY , Segolene De Gavriloff
发明人： Renaud MAROY , Segolene De Gavriloff
IPC分类号： G06K9/00
CPC分类号： G06F19/704
摘要： This extraction method in a structure of a living organism from a measurement image of the kinetics of the active ingredient comprising a plurality of regions of interest inside each of which the kinetics of the active ingredient are measured, comprises the following steps: determining (30) a plurality of sets of kinetics, the determined sets of kinetics being different from each other and each determined set of kinetics including several measured kinetics; defining (32) at least one kinetic model, parameters of the defined kinetics model being formed by the parameters of the input function and the pharmacokinetic parameters; estimating (34) the input function and the pharmacokinetic parameters by resolving the kinetic model defined from the determined set of kinetics; and deducing (36) the final input function and the final pharmacokinetic parameters.
摘要翻译：来自活性成分的活性成分的动力学的测定图像的活性成分的结构的提取方法包括测定活性成分的动力学的各个感兴趣区域，包括以下步骤：确定（30）多组动力学，确定的动力学集合彼此不同，并且每个确定的动力学集合包括几个测量的动力学; 定义（32）至少一个动力学模型，所定义的动力学模型的参数由输入函数的参数和药代动力学参数形成; 通过解决从确定的动力学集合定义的动力学模型来估计（34）输入函数和药代动力学参数; 并推导（36）最终输入函数和最终药代动力学参数。

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