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1. 发明申请

US20050143317A1 Compounds and methods for treatment of thrombosis 有权
标题翻译：用于治疗血栓形成的化合物和方法
公开(公告)号：US20050143317A1
公开(公告)日：2005-06-30
申请号：US10817248
申请日：2004-04-02
申请人： Sherin Abdel-Meguid , Robert Babine , Hongfeng Deng , Lei Jin , Jian Lin , Scott Magee , Harold Meyers , Pramod Pandey , Michael Rynkiewicz , David Weaver , Zihong Gho , Thomas Bannister
发明人： Sherin Abdel-Meguid , Robert Babine , Hongfeng Deng , Lei Jin , Jian Lin , Scott Magee , Harold Meyers , Pramod Pandey , Michael Rynkiewicz , David Weaver , Zihong Gho , Thomas Bannister
IPC分类号： A61K20060101 , A61K38/00 , A61K38/04 , C07K2/00 , C07K5/04 , C07K5/06 , C07K5/065 , C07K5/078
CPC分类号： C07K5/06078 , A61K38/00 , C07K5/06034 , C07K5/06139 , C07K5/06191
摘要： The present invention provides compounds that inhibit Factor XIa and methods of preventing or treating undesired thrombosis by administering a compound of the invention to a mammal. The invention also provides three-dimensional structures of Factor XIa and methods for designing or selecting additional Factor XIa inhibitors using these structures.
摘要翻译：本发明提供了通过向哺乳动物施用本发明的化合物来抑制因子XIa的化合物和预防或治疗不期望的血栓形成的方法。本发明还提供了因子XIa的三维结构以及使用这些结构设计或选择另外的因子XIa抑制剂的方法。

2. 发明授权

US4673859A Induction motor synthesis control apparatus and method 失效
标题翻译：感应电动机综合控制装置及方法
公开(公告)号：US4673859A
公开(公告)日：1987-06-16
申请号：US696814
申请日：1985-01-31
申请人： David J. Shero , Habib Dadpey , C. Scott Magee
发明人： David J. Shero , Habib Dadpey , C. Scott Magee
IPC分类号： B60L11/18 , H02P27/04 , H02P5/40
CPC分类号： B60L11/1803 , H02P27/08 , B60L2220/12 , Y02T10/646 , Y02T10/648 , Y02T10/7005 , Y02T10/7258
摘要： An arrangement of interconnected timers is provided for operation with a microprocessor programmed to determine time delay counts that are fed out to these timers such that the timers can take care of the actual task of firing GTO inverter switches or not firing GTO inverter switches coupled with an AC traction motor for a vehicle. It is necessary to have correct transitions between the minus GTO switch and the plus GTO switch being ON for providing the desired motor voltage conditions with minimum electromagnetic interference in relation to the power supply. In addition the use of timer queues in complicated synthesis modes like the PWM and the quasi six-step operates to give the microprocessor adequate operating time for reasonable control signal time duration calculations. The timers are synchronized in hardware by a single crystal frequency, and they are synchronized in software such that the three phase independent waveforms stay 120.degree. apart.
摘要翻译：提供了互连定时器的布置，用于与被编程用于确定馈送到这些定时器的时间延迟计数的微处理器进行操作，使得定时器可以处理点火GTO逆变器开关的实际任务，或者不触发GTO逆变器开关用于车辆的交流牵引电动机。必须在负GTO开关和正GTO开关之间进行正确的转换，以提供与电源相关的最小电磁干扰的所需电机电压条件。此外，在复杂的合成模式（如PWM和准六步）中使用定时器队列可以为微处理器提供合理的控制信号持续时间计算的足够的工作时间。定时器通过单晶体频率在硬件上同步，并且它们在软件中同步，使得三相独立波形间隔120°。

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