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1. 发明授权

US11771753B2 Preparation of flagellin vaccine adjuvant-based vaccine to induce production of antibody recognizing conformation of antigens, and application thereof 有权
公开(公告)号：US11771753B2
公开(公告)日：2023-10-03
申请号：US17116104
申请日：2020-12-09
申请人： Joon Haeng Rhee , Shee Eun Lee , Kwangjoon Jeong , Sang Chul Park , Wenzhi Tan
发明人： Joon Haeng Rhee , Shee Eun Lee , Kwangjoon Jeong , Sang Chul Park , Wenzhi Tan
IPC分类号： A61K39/02 , C07K14/47 , A61K39/00 , A61K35/68 , A61P25/28 , A61K9/00 , A61K39/12 , A61P31/18
CPC分类号： A61K39/107 , A61K9/0019 , A61K35/68 , A61K39/00 , A61K39/02 , A61K39/12 , A61P25/28 , A61P31/18 , C07K14/47 , A61K2039/51 , A61K2039/6075
摘要： The present invention provides a vaccine composition for use in neurodegenerative diseases and an infectious virus vaccine composition for inducing an antibody recognizing the conformation of antigens. The vaccine composition of the present invention induces the production of an antibody recognizing the conformation of antigens. The antibody recognizing the conformation of antigens has high specificity for an antigen, and thus can be useful for ameliorating, preventing or treating diseases.

2. 发明授权

US08735164B2 Fluoride distillation apparatus and quantifying method of sodium monofluorophosphate in toothpaste using same 有权
标题翻译：氟化物蒸馏装置和使用相同的牙膏中的单氟磷酸钠的定量方法
公开(公告)号：US08735164B2
公开(公告)日：2014-05-27
申请号：US13511446
申请日：2010-11-19
申请人： Sang Chul Park , Boo Min Kim , Ji Hee Jung , Min Kee Kim , Hye Jin Jeong
发明人： Sang Chul Park , Boo Min Kim , Ji Hee Jung , Min Kee Kim , Hye Jin Jeong
IPC分类号： G01N31/00
CPC分类号： C01B25/455
摘要： The present invention relates to a fluoride distillation apparatus and a method for quantifying sodium monofluorophosphate among fluorides using the same, which increases the acid resistance of the hard tissues of the teeth and promotes remineralization of initial caries lesion.
摘要翻译：本发明涉及氟化物蒸馏装置和使用该氟化物的氟化物中的单氟磷酸钠的量化方法，其增加了牙齿硬组织的耐酸性，并促进了初始龋齿病变的再矿化。

3. 发明授权

US08546347B2 Composition for treatment and improvement of diabetes comprising caveolin as active ingredient and a method for treatment of diabetes using it 有权
标题翻译：用于治疗和改善糖尿病的组合物，其包含窖蛋白作为活性成分，以及使用其治疗糖尿病的方法
公开(公告)号：US08546347B2
公开(公告)日：2013-10-01
申请号：US12736218
申请日：2008-03-21
申请人： Sang Chul Park , Yoon Sin Oh
发明人： Sang Chul Park , Yoon Sin Oh
IPC分类号： A01N43/04 , A01N63/00 , C12N15/00 , C12N15/63 , C07H21/04
CPC分类号： A61K38/177 , G01N33/6893 , G01N2800/042
摘要： The present invention relates to a composition for the treatment and improvement of diabetes comprising caveolin as an active ingredient and a method for treating diabetes using the same, more precisely a composition comprising caveolin-1 as an active ingredient for the treatment and improvement of type II diabetes which is age-dependent but not showing obesity symptom and a method for treating diabetes using the same. The treatment method and composition of the present invention is very effective in improving and treating diabetes by regulating insulin sensitivity by increasing caveolin level in muscle tissues of type II diabetes patient which is age-dependent but not showing obesity symptom.
摘要翻译：本发明涉及用于治疗和改善糖尿病的组合物，其包含窖蛋白作为活性成分，以及使用该组合物治疗糖尿病的方法，更准确地说，包含窖蛋白-1作为治疗和改善II型的活性成分的组合物年龄依赖性但不显示肥胖症状的糖尿病及使用其的糖尿病治疗方法。本发明的治疗方法和组合通过增加年龄依赖但不显示肥胖症状的II型糖尿病患者的肌肉组织中的窖蛋白水平来调节胰岛素敏感性，对于改善和治疗糖尿病非常有效。

4. 发明申请

US20120022849A1 PLC SYMBOL STRUCTURE FOR A PLC CODE FOR AUTOMATICALLY GENERATING AN INPUT/OUTPUT MODEL, AND SIMULATION APPARATUS AND SIMULATION METHOD FOR TESTING THE PLC CODE USING SAME 有权
标题翻译：用于自动生成输入/输出模型的PLC代码的PLC符号结构，以及用于测试PLC代码的仿真设备和模拟方法
公开(公告)号：US20120022849A1
公开(公告)日：2012-01-26
申请号：US13260365
申请日：2010-03-24
申请人： Gi Nam Wang , Sang Chul Park , Hyeong Tae Park
发明人： Gi Nam Wang , Sang Chul Park , Hyeong Tae Park
IPC分类号： G06F17/50
CPC分类号： G05B19/054 , G05B2219/13186
摘要： Disclosed are a PLC (Programmable Logic Controller) symbol structure for a PLC code for automatically generating an input/output model, and a simulation apparatus and a simulation method for testing the PLC code using the same. In one embodiment, a computer-readable recording medium records a PLC code including a plurality of PLC symbols, wherein each of the PLC symbols includes a plurality of levels identified by an identifier, and a computer automatically generates an input/output model using the structure of each of the PLC symbols, thereby performing a simulation for testing the PLC code. The PLC symbol structure according to one embodiment systematically contains information required for automatically generating the input/output model, making it possible to automatically generate the input/output model for testing the PLC code in an easier manner without knowledge of simulation and modeling, and reducing the time consumed and the labor required for generating the input/output model.
摘要翻译：公开了用于自动生成输入/输出模型的PLC代码的PLC（可编程逻辑控制器）符号结构，以及用于使用该PLC代码测试PLC代码的仿真装置和仿真方法。在一个实施例中，计算机可读记录介质记录包括多个PLC符号的PLC代码，其中每个PLC符号包括由标识符标识的多个级别，并且计算机使用该结构自动生成输入/输出模型的每个PLC符号，从而执行用于测试PLC代码的模拟。根据一个实施例的PLC符号结构系统地包含自动生成输入/输出模型所需的信息，使得可以以更简单的方式自动生成用于测试PLC代码的输入/输出模型，而不需要了解模拟和建模，并且减少生产输入/输出模型所需的时间和劳动时间。

5. 发明申请

US20110150899A1 SENESCENCE CONTROL COMPOSITION CONTAINING EXTRACELLULAR MATRIX COMPONENTS, AND SENESCENCE CONTROL METHOD FOR SENESCENT CELLS USING SAME 审中-公开
标题翻译：包含细胞外基质组分的感觉控制组合物，以及使用其的感光细胞的感觉控制方法
公开(公告)号：US20110150899A1
公开(公告)日：2011-06-23
申请号：US12737631
申请日：2009-07-29
申请人： Sang Chul Park , Kyung A. Cho , Moon Kyung Ha , Hae Ri Choi
发明人： Sang Chul Park , Kyung A. Cho , Moon Kyung Ha , Hae Ri Choi
IPC分类号： A61K39/395 , A61K35/12 , A61P43/00
CPC分类号： A61K35/33 , C07K14/70546 , C07K16/2839 , C12N15/1138 , C12N2310/14
摘要： The present invention relates to a composition containing an extracellular matrix for controlling aging and a method for controlling aging by using the same. The composition for controlling aging and the method for controlling aging have an effect for recovering the biological function of the aged aging cell, and the amount of the expression of the integrin alpha V that is a cell membrane protein and is reduced if aging is again increased in the aging cell recovered by the young extracellular matrix. However, when the amount of expression of the integrin alpha V is artificially decreased by using siRNA and antibody, the aging cell is not recovered by the extracellular matrix extracted from the young cell.
摘要翻译：本发明涉及包含用于控制老化的细胞外基质的组合物和使用该组合物来控制老化的方法。用于控制老化的组合物和控制老化的方法具有回收老化细胞的生物功能的作用，并且作为细胞膜蛋白的整联蛋白αV的表达量并且如果老化再次增加则其降低在衰老细胞中由年轻的细胞外基质回收。然而，当通过使用siRNA和抗体人体减少整联蛋白αV的表达量时，老化细胞不能通过从年轻细胞提取的细胞外基质来回收。

6. 发明授权

US07001769B2 Nucleic acid sequences and proteins involved in cellular senescence 有权
标题翻译：涉及细胞衰老的核酸序列和蛋白质
公开(公告)号：US07001769B2
公开(公告)日：2006-02-21
申请号：US10363924
申请日：2001-07-06
申请人： Sang-Chul Park , Woong-Yang Park , Jeong-Soo Park , Kyung-A Cho , Deok-In Kim
发明人： Sang-Chul Park , Woong-Yang Park , Jeong-Soo Park , Kyung-A Cho , Deok-In Kim
IPC分类号： C12N5/02 , C12P21/06
CPC分类号： G01N33/5008 , A61K38/1709 , A61K38/177 , C12Q1/6883 , C12Q2600/154 , C12Q2600/158 , G01N33/502 , G01N33/5044 , G01N33/68 , G01N33/6893 , G01N2510/00
摘要： The present invention relates to nucleic acid sequences and proteins involved in senescence and particularly, to nucleic acid sequences and proteins including amphiphysin and caveolin involved in cellular senescence and their use.
摘要翻译：本发明涉及参与衰老的核酸序列和蛋白质，特别涉及涉及细胞衰老的核酸序列和蛋白质，包括两亲蛋白和小窝蛋白及其用途。

7. 发明授权

US06864937B2 In-plane switching mode liquid crystal display device with peripheral circuit lines for shielding 有权
标题翻译：具有屏蔽外围电路线的面内开关模式液晶显示装置
公开(公告)号：US06864937B2
公开(公告)日：2005-03-08
申请号：US09892883
申请日：2001-06-28
申请人： Hong Man Moon , Sang Chul Park , Jae Young Chung
发明人： Hong Man Moon , Sang Chul Park , Jae Young Chung
IPC分类号： G02F1/136 , G02F1/1343 , G02F1/1345
CPC分类号： G02F1/1345 , G02F1/134363
摘要： A liquid crystal display device that uses in-plane switching is capable of eliminating a stain generated at an outer area of a thin film transistor array and minimizing a time delay of a common voltage applied to a thin film transistor array. In the device, a plurality of data lines apply data signals to a thin film transistor array. A plurality of gate lines apply gate signals to the thin film transistor array. A plurality of common voltage lines apply a common voltage to the thin film transistor array. The common voltage lines are provided at the outer area of the thin film transistor array and are spaced from the thin film transistor array by a distance of more than 1 to 1.5 mm. A plurality of dummy signal lines are arranged in parallel to the common voltage lines and adjacent to the common voltage lines provided at the outer area of the thin film transistor array to apply alternating current signals.
摘要翻译：使用平面内切换的液晶显示装置能够消除在薄膜晶体管阵列的外部区域产生的污点并使施加到薄膜晶体管阵列的公共电压的时间延迟最小化。在该器件中，多条数据线将数据信号施加到薄膜晶体管阵列。多个栅极线将栅极信号施加到薄膜晶体管阵列。多个公共电压线将公共电压施加到薄膜晶体管阵列。公共电压线设置在薄膜晶体管阵列的外部区域处，并且与薄膜晶体管阵列隔开大于1至1.5mm的距离。多个虚拟信号线与公共电压线平行布置，并且与设置在薄膜晶体管阵列的外部区域处的公共电压线相邻，以施加交流信号。

8. 发明授权

US06169109A Method of inactivation of viral and bacterial blood contaminants 失效
标题翻译：灭活病毒和细菌血液污染物的方法
公开(公告)号：US06169109A
公开(公告)日：2001-01-02
申请号：US09148238
申请日：1998-09-04
申请人： Sang Chul Park , Raymond P. Goodrich, Jr. , Nagender Yerram , Samuel O. Sowemimo-Coker , Matthew S. Platz , Brian M. Aquila
发明人： Sang Chul Park , Raymond P. Goodrich, Jr. , Nagender Yerram , Samuel O. Sowemimo-Coker , Matthew S. Platz , Brian M. Aquila
IPC分类号： A61K3135
CPC分类号： C12N7/00 , A61K35/16 , A61K35/19 , A61K38/00 , A61K41/0019 , A61K41/0057 , A61L2/0011 , A61L2/0035 , A61L2/0076 , A61L2/0082 , A61L2202/22 , C07K14/755 , C12N9/644 , C12N2710/16163 , C12N2710/16663 , C12N2740/16063 , C12N2760/20263 , C12N2770/36161 , C12N2770/36163 , C12Y304/21022
摘要： Viral and bacterial contaminants present in biological solutions are inactivated by mixing one of a novel class of photosensitizer with said solution and irradiating the mixture.
摘要翻译：生物溶液中存在的病毒和细菌污染物通过将新型光敏剂之一与所述溶液混合并照射混合物来灭活。

9. 发明授权

US5827924A Polymer sealant microencapsulated by polyurethane reaction and its binder solution 失效
标题翻译：聚合物密封胶通过聚氨酯反应及其粘合剂溶液微胶囊化
公开(公告)号：US5827924A
公开(公告)日：1998-10-27
申请号：US564219
申请日：1995-12-15
申请人： In-Hwan Park , Kyung-Suck Min , Sang-Chul Park
发明人： In-Hwan Park , Kyung-Suck Min , Sang-Chul Park
IPC分类号： B01J13/16 , C08L75/04 , C09J5/00 , F16B11/00 , F16B39/02 , B32B19/00 , C08F8/30 , C08L27/00 , C08L75/00
CPC分类号： B01J13/16 , C09J9/005 , F16B39/021 , C08L75/04 , C09J2203/102 , C09J2475/00 , F16B11/006 , Y10T428/29 , Y10T428/2984 , Y10T428/2985 , Y10T428/2987
摘要： This invention relates to polymer sealant microencapsulated by polyurethane reaction and its binder solution, particularly employing threaded mechanical fasteners such as bolt-nuts, screws, pipe joints and threaded nails, etc. The microcapsules are prepared by interfacial polyurethane reaction of triisocyanate with poly-functional alcohol under the aqueous oil-droplets solution containing vinyl monomers, oligomers, redox initiators and organic solvents together as core materials of the microcapsules. The binder solution of the microcapsules is prepared by dissolving chloroprene, polyester acrylate, urethane acrylate, carboxyl- or hydroxy-modified vinylchloride-vinylacetate copolymer, coinitiators and fillers in a mixture of tetrachloroethylene and toluene.
摘要翻译： PCT No.PCT / KR94 / 00073 Sec。 371 1995年12月15日第 102（e）1995年12月15日日期PCT PCT日期1994年6月16日PCT公布。公开号WO94 / 29603 日期1994年12月22日本发明涉及通过聚氨酯反应进行微胶囊化的聚合物密封胶及其粘合剂溶液，特别是采用螺栓螺母，螺栓，管接头和螺纹钉等螺纹机械紧固件。微胶囊通过界面聚氨酯反应三异氰酸酯与多官能醇在含有乙烯基单体，低聚物，氧化还原引发剂和有机溶剂的水性油滴溶液下一起作为微胶囊的核心材料。通过将氯丁二烯，聚酯丙烯酸酯，氨基甲酸酯丙烯酸酯，羧基或羟基改性的氯乙烯 - 乙酸乙烯酯共聚物，共引发剂和填料溶解在四氯乙烯和甲苯的混合物中来制备微胶囊的粘合剂溶液。

10. 发明授权

US5616500A Trichohyalin and transglutaminase-3 and methods of using same 失效
标题翻译： Trichohyalin和转谷氨酰胺酶-3及其使用方法
公开(公告)号：US5616500A
公开(公告)日：1997-04-01
申请号：US56200
申请日：1993-04-30
申请人： Peter M. Steinert , In-Gyu Kim , Soo-Il Chung , Sang-chul Park
发明人： Peter M. Steinert , In-Gyu Kim , Soo-Il Chung , Sang-chul Park
IPC分类号： A23J3/00 , A61K8/64 , A61L24/10 , A61L26/00 , A61L27/22 , A61Q19/00 , C07K14/47 , C12N9/10 , C12N15/12 , C12N15/00 , C07H19/00 , C12P21/06 , C12H9/10
CPC分类号： C12N9/1044 , A23J3/04 , A61K8/64 , A61L24/106 , A61L26/0047 , A61L27/227 , A61Q19/00 , C07K14/47 , C12N9/10
摘要： The sequences of a pair of human proteins, trichohyalin and transglutaminase-3, in addition to the sequence of the mouse transglutaminase-3 protein, have been discovered. The enzyme transglutaminase-3 is used to cross-link the structural protein trichohyalin in order to form a gel.
摘要翻译：已经发现了除了小鼠转谷氨酰胺酶-3蛋白的序列之外的一对人蛋白质，毛发蛋白和转谷氨酰胺酶-3的序列。酶转谷氨酰胺酶-3用于交联结构蛋白质毛滴虫蛋白以形成凝胶。

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