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1. 发明授权

US06296622B1 Endoluminal device delivery system using axially recovering shape memory material 有权
标题翻译：使用轴向恢复形状记忆材料的腔内装置输送系统
公开(公告)号：US06296622B1
公开(公告)日：2001-10-02
申请号：US09218117
申请日：1998-12-21
申请人： Daniel R. Kurz , Rose Y. Wong , Crystal K. Sein-Lwyn , David A. Ferrera , Lok A. Lei , Nicholas C. Debeer
发明人： Daniel R. Kurz , Rose Y. Wong , Crystal K. Sein-Lwyn , David A. Ferrera , Lok A. Lei , Nicholas C. Debeer
IPC分类号： A61M1100
CPC分类号： A61B17/12022 , A61B17/1214 , A61B2017/00867 , A61B2017/1205 , A61B2017/12072 , A61B2017/12077 , A61B2018/00005 , A61F2/95
摘要： The endoluminal device delivery system and method for delivering an endoluminal device within a body lumen uses shape memory material in the form of a tubular collar to engage the endoluminal device during delivery to the desired location. The endoluminal device is engaged internally within the tubular collar either mechanically by crimping the tubular collar around a portion of the endoluminal device, or through an adhesive bond. The tubular collar can be crimped about a rounded portion of the stem of the endoluminal device. Once the endoluminal device is maneuvered through the body lumens to the desired location, it is decoupled from the delivery system by applying heat to the tubular collar of shape memory material. When the tubular collar has been heated to a sufficient temperature, it will transition to a rubbery state and shrink in length, thereby retracting completely back on to the optical fiber, causing the distal end of the optical fiber to engage the endoluminal device and dislodge it from the tubular collar. An interlocking assembly can also be utilized at the stem portion of the endoluminal therapeutic device to releaseably connect the endoluminal therapeutic device to the elongated pusher member. The body of shape memory material can also be bonded to both the pusher member and the endoluminal device, with the tubular collar being scored to break when the tubular collar changes from the stressed configuration to the recovered configuration. A collet can also be mounted to the pusher member and disposed within.
摘要翻译：用于在体腔内递送腔内装置的腔内装置递送系统和方法使用呈管状套环形式的形状记忆材料，以在输送到期望位置期间接合腔内装置。腔内装置通过将管状颈环围绕腔内装置的一部分或通过粘合剂粘合而机械地接合在管状颈部内部。管状环可围绕内腔装置的茎的圆形部分卷曲。一旦腔内装置通过体腔流动到期望的位置，则通过将热量施加到形状记忆材料的管状环上而与输送系统分离。当管状套管已经被加热到足够的温度时，它将转变到橡胶状态并且长度收缩，从而完全退回到光纤上，导致光纤的远端接合腔内装置并将其移开从管状领。也可以在腔内治疗装置的茎部处使用互锁组件以将腔内治疗装置可释放地连接到细长的推动器构件。形状记忆材料的主体还可以结合到推动器构件和腔内装置上，当管状套环从应力构型改变到恢复构型时，管状环被刻痕以破裂。夹头也可以安装到推动器构件并且设置在其内。

2. 发明授权

US06240231B1 Variable stiffness fiber optic shaft 有权
标题翻译：可变刚度光纤轴
公开(公告)号：US06240231B1
公开(公告)日：2001-05-29
申请号：US09219572
申请日：1998-12-22
申请人： David A. Ferrera , Nicholas C. Debeer , Thuzar Han , Daniel R. Kurz , Rose Y. Wong
发明人： David A. Ferrera , Nicholas C. Debeer , Thuzar Han , Daniel R. Kurz , Rose Y. Wong
IPC分类号： G02B604
CPC分类号： G02B6/403 , A61B18/24 , G02B6/04 , G02B6/241 , G02B6/3887 , G02B23/26
摘要： The variable stiffness optical fiber shaft includes a optical fiber, and at least one coaxial layer of heat shrink polymer disposed over the optical fiber of a length shorter than the optical fiber, to provide variations in stiffness along the length of the shaft. The variable stiffness optical fiber shaft preferably includes a plurality of coaxial layers of heat shrink polymer encapsulating the optical fiber, extending from the proximal end of the optical fiber toward the distal end, the plurality of coaxial layers having different lengths to provide said optical fiber shaft with varying stiffness over the length of the optical fiber shaft. The plurality of coaxial layers can be arranged in successive progressively shorter coaxial layers, and can be formed of heat shrink polymeric material, such as polyethylene, PTFE, PEEK, PET or PPS. The variable stiffness optical fiber shaft can also include a coaxial strain relief member disposed over the outer coaxial polymer layers at the proximal end, and a connecting hub disposed over the strain relief member. The variable stiffness optical fiber shaft can also include a hypo tube attached to the optical fiber, and a reinforcing braid attached over the optical fiber, as well as a radiopaque marker that can be a reinforcing coil. A shape memory collar can also be attached over the distal end of the optical fiber, with a distal sheath extending over a portion of the shape memory collar. A hub can also be attached over the proximal portion of the optical fiber. A method of constructing the variable stiffness optical fiber shaft is also provided.
摘要翻译：可变刚度光纤轴包括光纤，以及设置在比光纤短的长度的光纤上的至少一个热收缩聚合物的同轴层，以提供沿轴的长度的刚度变化。可变刚度光纤轴优选地包括多个同轴层，其包封光纤的热收缩聚合物，从光纤的近端延伸到远端，多个同轴层具有不同的长度以提供所述光纤轴在光纤轴的长度上具有变化的刚度。多个同轴层可以以相继逐渐缩短的同轴层布置，并且可以由热收缩聚合材料如聚乙烯，PTFE，PEEK，PET或PPS形成。可变刚度光纤轴还可以包括设置在近端的外同轴聚合物层上的同轴应变消除构件和设置在应变消除构件上的连接毂。可变刚度光纤轴还可以包括附接到光纤的低管，以及附着在光纤上的加强编织物，以及可以是加强线圈的不透射线的标记。形状记忆轴环还可以附接在光纤的远端上，远端鞘在形状记忆颈圈的一部分上延伸。轮毂也可以附着在光纤的近端部分上。还提供了构造可变刚度光纤轴的方法。

3. 发明授权

US5972019A Mechanical clot treatment device 失效
标题翻译：机械凝血治疗装置
公开(公告)号：US5972019A
公开(公告)日：1999-10-26
申请号：US869346
申请日：1997-06-05
申请人： Erik T. Engelson , Gene Samson , Kim Nguyen , Rose Y. Wong
发明人： Erik T. Engelson , Gene Samson , Kim Nguyen , Rose Y. Wong
IPC分类号： A61B17/00 , A61B17/22 , A61F2/82 , A61M25/00 , A61M25/04 , A61M25/10 , A61M29/00 , A61M29/02
CPC分类号： A61B17/3207 , A61B17/221 , A61B17/320725 , A61B17/32075 , A61B2017/22034 , A61B2017/2212 , A61F2/013 , A61M2025/1095 , A61M25/10 , A61M29/02
摘要： This is a medical device. In particular, it is a surgical device usually delivered through an intravascular catheter. It may be used in several ways. It may, for instance, be used to open a clear passageway adjacent thrombus to allow both blood and medication to bypass the clot. It may be used to pierce and to remove thrombus. These thrombus are often found in tortuous vasculature. The device includes several sections. The device has a core element, typically a core wire. Placed around the distal end of the core element is a collapsible but preferably self expanding cage assembly. The cage assembly is preferably radio-opaque. The proximal end of the cage is typically is affixed to an actuator in such a way as to allow expansion of the cage after deployment. The cage assembly may have a generally conical distal or "trailing" portion when expanded and also a proximal section. The cage assembly may be used for collecting emboli or for displacing them to allow blood flow to resume. The proximal section may have various uses, e.g., for centering the collector assembly in the vascular lumen or for gathering larger amounts of the targeted clot or to act as a passageway for fluid flow. The assembly further may have an actuator which permits or causes the collector assembly to expand after deployment.
摘要翻译：这是一种医疗器械。特别地，它是通常通过血管内导管递送的手术装置。它可以以几种方式使用。例如，它可以用于打开邻近血栓的清晰通道，以允许血液和药物绕过凝块。它可以用于刺穿和去除血栓。这些血栓通常在曲折的脉管系统中发现。该设备包括几个部分。该装置具有核心元件，通常为芯线。围绕芯元件的远端放置的是可折叠但优选自膨胀的笼组件。笼组件优选地是不透射线的。保持架的近端通常被固定到致动器上，以允许在展开之后使笼膨胀。当膨胀时，笼组件可以具有大致锥形的远侧或“后退”部分，并且还具有近端部分。笼组件可以用于收集栓塞或用于移位它们以允许血流恢复。近端部分可以具有各种用途，例如用于将收集器组件对准在血管腔中或用于收集更大量的目标凝块或用作流体流动的通道。组件还可具有致动器，该致动器允许或导致收集器组件在展开之后膨胀。

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