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    • 1. 发明授权
    • Implantable prosthesis
    • 植入假体
    • US07404819B1
    • 2008-07-29
    • US09661623
    • 2000-09-14
    • Roger DariosRonald L. GreeneDennis CherokThomas J. CapuzzielloJames D. Mello
    • Roger DariosRonald L. GreeneDennis CherokThomas J. CapuzzielloJames D. Mello
    • A61B17/08A61F2/02
    • A61F2/02A61F2/0063A61F2002/009
    • An implantable prosthesis and a method of repairing an anatomical defect, such as a tissue or muscle wall defect, by promoting tissue growth thereto, while limiting the incidence of postoperative adhesions between a portion of the prosthesis and tissue or organs. The prosthesis is formed of a biologically compatible, flexible layer of repair fabric suitable for reinforcing tissue or muscle and closing anatomical defects, and a barrier layer for physically isolating at least a portion of one side of the fabric from areas likely to form adhesions. A peripheral barrier extends about at least a portion of the outer peripheral edge of the repair fabric to inhibit adhesions between the outer peripheral edge and adjacent tissue and organs. The repair fabric may include an outer margin that has been melted and resolidified to render the outer peripheral edge substantially impervious to tissue ingrowth. The barrier layer may be joined to the repair fabric with connecting stitches formed from PTFE to inhibit the formation of adhesions thereto.
    • 可植入假体和通过促进组织生长来修复诸如组织或肌肉壁缺陷的解剖缺陷的方法,同时限制假体的一部分与组织或器官之间的术后粘连的发生。 假体由适于加强组织或肌肉并闭合解剖缺陷的生物相容性柔韧的修复织物层形成,以及用于物理隔离织物的一侧的至少一部分与可能形成粘连的区域的阻挡层。 周边障碍物围绕修复织物的外围边缘的至少一部分延伸,以抑制外围边缘和相邻组织和器官之间的粘连。 修复织物可以包括已经熔化并重新固化以使外周边缘基本上不可渗透组织向内生长的外边缘。 阻挡层可以用由PTFE形成的连接针迹连接到修复织物,以抑制其粘附的形成。