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1. 发明申请

US20090012995A1 Method and apparatus for capture and distribution of broadband data 有权
标题翻译：用于捕获和分配宽带数据的方法和装置
公开(公告)号：US20090012995A1
公开(公告)日：2009-01-08
申请号：US11662841
申请日：2006-02-21
申请人： Mark Alan Sartor , Philip Wayne Miller , Arthur Robert Pope , Peter L. Demers , Nikhil Gagvani , Vincent Paragano , Daniel Clement Williams
发明人： Mark Alan Sartor , Philip Wayne Miller , Arthur Robert Pope , Peter L. Demers , Nikhil Gagvani , Vincent Paragano , Daniel Clement Williams
IPC分类号： G06F7/00
CPC分类号： H04N21/435 , H04N21/2187 , H04N21/235 , H04N21/25825 , H04N21/42202 , H04N21/84
摘要： A system and method for preparing for distribution to, distributing to and/or use by one or more devices broadband data associated with intelligence information garnered from an aerial vehicle (“AV”): The method may include obtaining from sensors coupled to the AV video depicting an area of surveillance, obtaining metadata associated with the video, aligning, temporally, the video and metadata, using reference information to align, spatially, the video and metadata, forming for distribution to the at least one device enhanced metadata as a function of the video, metadata and reference information, wherein the enhanced metadata is operable to enable displaying at the devices at least a portion of the video, whereby after receiving a distribution of the enhanced metadata, the devices are operable to display such portion of the video.
摘要翻译：一种用于准备向一个或多个设备分配，分发和/或使用与从空中客车（“AV”）获得的智能信息相关联的宽带数据的系统和方法：该方法可以包括从耦合到AV视频的传感器描绘监视区域，获得与视频关联的元数据，使视频和元数据在时间上对齐，使用参考信息来空间地对准视频和元数据，形成用于分发至少一个设备增强元数据作为所述视频，元数据和参考信息，其中所述增强元数据可操作以使得能够在所述设备处显示所述视频的至少一部分，由此在接收到所述增强元数据的分发之后，所述设备可操作以显示所述视频的所述部分。

2. 发明授权

US6113879A Composition comprising methylphenidate and another drug 失效
标题翻译：组合物包含哌甲酯和另一种药物
公开(公告)号：US6113879A
公开(公告)日：2000-09-05
申请号：US106870
申请日：1998-06-29
申请人： Andrew John McGlashan Richards , Nicholas Robert Pope
发明人： Andrew John McGlashan Richards , Nicholas Robert Pope
IPC分类号： C07D211/34 , A61K31/445 , A61K31/4458 , A61K33/00 , A61K45/00 , A61K45/06 , A61K49/00 , A01N33/02 , A01N43/06 , A61K9/16
CPC分类号： A61K45/06 , A61K31/445 , A61K31/4458 , A61K33/00 , Y10S514/81 , Y10S514/813 , Y10S514/922
摘要： A method of treating a subject that is undergoing methylphenidate therapy and concomitant therapy with another drug undergoes or interferes with P.sub.450 metabolism, wherein the methylphenidate is d-threo-methylphenidate.
摘要翻译：治疗正在进行哌甲酯治疗和伴随其他药物治疗的受试者的方法经历或干扰P450代谢，其中哌甲酯是D-苏氨哌甲酯。

3. 发明授权

US06468504B1 Composition comprising methylphenidate and another drug 失效
标题翻译：组合物包含哌甲酯和另一种药物
公开(公告)号：US06468504B1
公开(公告)日：2002-10-22
申请号：US09597384
申请日：2000-06-19
申请人： Andrew John McGlashan Richards , Nicholas Robert Pope
发明人： Andrew John McGlashan Richards , Nicholas Robert Pope
IPC分类号： A61K4900
CPC分类号： A61K45/06 , A61K31/445 , A61K31/4458 , A61K33/00 , Y10S514/81 , Y10S514/813 , Y10S514/922 , A61K2300/00
摘要： A process of treating a subject that is undergoing methylphenidate therapy and concomitant therapy with another drug undergoes or interferes with P450 metabolism, wherein the methylphenidate is d-threo-methylphenidate.
摘要翻译：治疗正在接受哌甲酯治疗和与另一种药物并用治疗的受试者的过程发生或干扰P450代谢，其中哌甲酯是D-苏氨哌甲酯。

4. 发明授权

US07267949B2 Composition comprising methylphenidate and another drug 失效
标题翻译：组合物包含哌甲酯和另一种药物
公开(公告)号：US07267949B2
公开(公告)日：2007-09-11
申请号：US10277413
申请日：2002-10-21
申请人： Andrew John McGlashan Richards , Nicholas Robert Pope
发明人： Andrew John McGlashan Richards , Nicholas Robert Pope
IPC分类号： C12Q1/68
CPC分类号： A61K45/06 , A61K31/445 , A61K31/4458 , A61K33/00 , Y10S514/81 , Y10S514/813 , Y10S514/922 , A61K2300/00
摘要： A process of treating a subject that is undergoing methylphenidate therapy and concomitant therapy with another drug undergoes or interferes with P450 metabolism, wherein the methylphenidate is d-threo-methylphenidate.
摘要翻译：治疗正在进行哌甲酯治疗和伴随其他药物治疗的受试者的过程经历或干扰P 450代谢，其中哌甲酯是D-苏氨哌甲酯。

5. 发明申请

US20060214104A1 Compositions and methods for analyzing biomolecules using mass spectroscopy 审中-公开
标题翻译：使用质谱分析生物分子的组合物和方法
公开(公告)号：US20060214104A1
公开(公告)日：2006-09-28
申请号：US11258363
申请日：2005-10-26
申请人： Robert Pope , John Leite , Mahbod Hajivandi , Charles Shevlin , Timothy Updyke
发明人： Robert Pope , John Leite , Mahbod Hajivandi , Charles Shevlin , Timothy Updyke
IPC分类号： B01D59/44 , H01J49/00
CPC分类号： G01N33/6851 , H01J49/04
摘要： Compositions and methods for mass spectroscopy are disclosed. The compositions and methods relate to the analysis of proteins and other biopolymers using mass spectroscopy, particularly matrix-assisted laser desorption time-of-flight mass spectrometry (MALDI-TOF MS).
摘要翻译：公开了用于质谱的组合物和方法。组合物和方法涉及使用质谱法，特别是基质辅助激光解吸飞行时间质谱（MALDI-TOF MS）分析蛋白质和其他生物聚合物。

6. 发明授权

US06827443B2 Method and system for prescribing and/or dispensing ophthalmic lenses 有权
标题翻译：用于处方和/或分发眼科镜片的方法和系统
公开(公告)号：US06827443B2
公开(公告)日：2004-12-07
申请号：US10181988
申请日：2002-10-09
申请人： Scott Warren Fisher , John Charles Bonnett , David Robert Pope
发明人： Scott Warren Fisher , John Charles Bonnett , David Robert Pope
IPC分类号： A61B314
CPC分类号： G02C7/061 , A61B3/113 , A61B5/11 , G02C7/027 , G02C7/028
摘要： A system and method for prescribing and/or dispensing ophthalmic lenses for a wearer. The method includes determining at least the wearer's individual visual behavioural patterns in terms of head movement and/or eye movement, processing those patterns with respect to a predetermined relationship between known head movements and/or eye movement characteristics and available ophthalmic lenses, such that the processing categorises wearers into a head movement or eye movement category that can then be used to produce a recommendation for an ophthalmic lens for the wearer. The system includes a transmitter unit (10), receivers on the user (12, 14) providing data to the interface (16). During a test a standard set of frames (18) are used, as are near (20) and intermediate (22) distance reading planes.
摘要翻译：一种用于为佩戴者处方和/或分配眼用透镜的系统和方法。该方法包括根据头部运动和/或眼睛运动确定至少佩戴者的各个视觉行为模式，根据已知的头部运动和/或眼睛运动特性和可用的眼科镜片之间的预定关系来处理这些图案，使得处理将佩戴者分类为头部运动或眼睛运动类别，然后可以用于产生针对佩戴者的眼科镜片的推荐。该系统包括发射机单元（10），用户（12,14）上的接收机向接口（16）提供数据。在测试期间，使用标准的一组框架（18），如靠近（20）和中间（22）距离读取平面。

7. 发明授权

US08692885B2 Method and apparatus for capture and distribution of broadband data 有权
标题翻译：用于捕获和分配宽带数据的方法和装置
公开(公告)号：US08692885B2
公开(公告)日：2014-04-08
申请号：US11662841
申请日：2006-02-21
申请人： Mark Alan Sartor , Philip Wayne Miller , Arthur Robert Pope , Peter L. Demers , Nikhil Gagvani , Vincent Paragano , Daniel Clement Williams
发明人： Mark Alan Sartor , Philip Wayne Miller , Arthur Robert Pope , Peter L. Demers , Nikhil Gagvani , Vincent Paragano , Daniel Clement Williams
IPC分类号： H04N7/18
CPC分类号： H04N21/435 , H04N21/2187 , H04N21/235 , H04N21/25825 , H04N21/42202 , H04N21/84
摘要： A system and method for preparing for distribution to, distributing to and/or use by one or more devices broadband data associated with intelligence information garnered from an aerial vehicle (“AV”): The method may include obtaining from sensors coupled to the AV video depicting an area of surveillance, obtaining metadata associated with the video, aligning, temporally, the video and metadata, using reference information to align, spatially, the video and metadata, forming for distribution to the at least one device enhanced metadata as a function of the video, metadata and reference information, wherein the enhanced metadata is operable to enable displaying at the devices at least a portion of the video, whereby after receiving a distribution of the enhanced metadata, the devices are operable to display such portion of the video.
摘要翻译：一种用于准备向一个或多个设备分配，分发和/或使用与从空中客车（“AV”）获得的智能信息相关联的宽带数据的系统和方法：该方法可以包括从耦合到AV视频的传感器描绘监视区域，获得与视频关联的元数据，使视频和元数据在时间上对齐，使用参考信息来空间地对准视频和元数据，形成用于分发至少一个设备增强元数据作为所述视频，元数据和参考信息，其中所述增强元数据可操作以使得能够在所述设备处显示所述视频的至少一部分，由此在接收到所述增强元数据的分发之后，所述设备可操作以显示所述视频的所述部分。

8. 发明授权

US07313252B2 Method and system for improving video metadata through the use of frame-to-frame correspondences 有权
标题翻译：通过使用帧到帧对应来改进视频元数据的方法和系统
公开(公告)号：US07313252B2
公开(公告)日：2007-12-25
申请号：US11390700
申请日：2006-03-27
申请人： Bogdan Calin Mihai Matei , Clay Douglas Spence , Arthur Robert Pope , Barbara Viviane Hanna , Michael Wade Hansen
发明人： Bogdan Calin Mihai Matei , Clay Douglas Spence , Arthur Robert Pope , Barbara Viviane Hanna , Michael Wade Hansen
IPC分类号： G06K9/00 , H04N7/18
CPC分类号： H04N7/183 , G06T7/277 , G06T7/74
摘要： A method and system for improving the accuracy and timeliness of video metadata by incorporating information related to the motion of the camera as derived from the video imagery itself. Frame-to-frame correspondences are used to accurately estimate changes in camera pose. While the method and system do not require geo-registration, geo-registration results, if available, may be considered in processing the video images and generating improved camera pose estimates.
摘要翻译：一种用于通过结合从视频图像本身导出的与摄像机的运动相关的信息来提高视频元数据的准确性和及时性的方法和系统。帧对帧对应用于准确估计摄像机姿态的变化。虽然方法和系统不需要地理注册，但是在处理视频图像并产生改进的相机姿态估计时可以考虑地理注册结果（如果可用）。

9. 发明申请

US20070105181A1 Identification of cancer biomarkers and phosphorylated pdroteins 审中-公开
标题翻译：鉴定癌症生物标志物和磷酸化pdroteins
公开(公告)号：US20070105181A1
公开(公告)日：2007-05-10
申请号：US11417264
申请日：2006-05-04
申请人： Robert Pope , Xiquan Liang , Mahbod Hajivandi , John Leite
发明人： Robert Pope , Xiquan Liang , Mahbod Hajivandi , John Leite
IPC分类号： C12Q1/37
CPC分类号： G01N33/57415 , G01N33/57496 , G01N33/60 , Y10T436/143333
摘要： Methods are provided for identifying proteins that are differentially expressed in disease state and normal cells. Stable isotope labeling of cells in culture allows for the identification of a multiplicity of proteins whose differential abundance in normal and disease state cells can be indicative of the disease state. Biomarkers are identified for breast cancer, in which the biomarkers are proteins having a two-fold or greater difference in abundance between breast cancer and normal cells. Identified biomarkers can be used detection methods that can provide diagnosis, typing, staging, or prognosis of cancer, such as breast cancer, or can be used to predict the response of cancer, such as breast cancer, to one or more anti-cancer agents.
摘要翻译：提供了用于鉴定在疾病状态和正常细胞中差异表达的蛋白质的方法。培养物中细胞的稳定同位素标记允许鉴定多种蛋白质，其正常和疾病状态细胞中的差异丰度可以指示疾病状态。鉴定乳腺癌的生物标志物，其中生物标志物是乳腺癌和正常细胞之间丰度差异大于2倍或更大的蛋白质。可以使用识别的生物标志物可以提供诸如乳腺癌的癌症的诊断，分型，分期或预后的检测方法，或者可以用于预测癌症如乳腺癌对一种或多种抗癌剂的反应。

10. 发明申请

US20070031911A1 Isotopically-labeled proteome standards 有权
标题翻译：同位素标记的蛋白质组标准
公开(公告)号：US20070031911A1
公开(公告)日：2007-02-08
申请号：US11368996
申请日：2006-03-07
申请人： John Leite , Robert Pope , Mahbod Hajivandi , Xiquan Liang
发明人： John Leite , Robert Pope , Mahbod Hajivandi , Xiquan Liang
IPC分类号： C12Q1/37 , G01N33/50
CPC分类号： G01N27/62 , G01N33/60 , G01N33/6848 , G01N33/6851 , G01N2458/15 , Y10T436/24
摘要： The invention provides methods for quantifying biomolecules, such as polypeptides in mass spectrometric analysis. The methods include use of a biomolecule standard having at least one atomic isotope different than that of the naturally occurring isotopes in the biomolecule of interest. Methods of the present invention also include methods for quantifying biomolecules where the copy biomolecule standard is made by expressing the biomolecule using a recombinant cell. Further included are the biomolecule standards themselves, method for making such standards, kits, systems, reagents, and engineered cells relating to the use of biomolecule standards in mass spectrometric analysis.
摘要翻译：本发明提供了在质谱分析中定量生物分子例如多肽的方法。该方法包括使用具有与感兴趣的生物分子中天然存在的同位素不同的至少一个原子同位素的生物分子标准。本发明的方法还包括用于定量生物分子的方法，其中通过使用重组细胞表达生物分子来制备复制生物分子标准物。还包括生物分子标准本身，制备此类标准的方法，试剂盒，系统，试剂和与质谱分析中使用生物分子标准有关的工程细胞。

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