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1. 发明授权

US06805686B1 Autoinjector with extendable needle protector shroud 有权
标题翻译：自动进样器带有可延长的针头保护罩
公开(公告)号：US06805686B1
公开(公告)日：2004-10-19
申请号：US10430710
申请日：2003-05-06
申请人： Marwan A. Fathallah , Richard W. Grabenkort
发明人： Marwan A. Fathallah , Richard W. Grabenkort
IPC分类号： A61M520
CPC分类号： A61M5/2033 , A61M5/3202 , A61M5/326 , A61M2005/206 , A61M2005/2073 , A61M2005/3109 , A61M2005/3247
摘要： The invention provides a syringe and a method for using the same. The syringe includes a housing having a reservoir disposed therein and a plunger to be received by the reservoir, the plunger being moveable between a first plunger position and a second plunger position. The syringe also includes a plunger spring to urge the plunger toward the second plunger position and an actuator to deploy the plunger spring. The syringe also includes a needle proximate the distal end of the housing displaceable from a first needle position to a second needle position, and a shroud coupled with the housing. The shroud is moveable between a retracted position and an extended position, the shroud surrounding at least a portion of the needle when in the extended position. The syringe also includes an interlocking assembly, a shroud spring, and a locking assembly configured to inhibit movement of the shroud.
摘要翻译：本发明提供一种注射器及其使用方法。注射器包括具有设置在其中的储存器的壳体和由储存器容纳的柱塞，柱塞可在第一柱塞位置和第二柱塞位置之间移动。注射器还包括柱塞弹簧，以将柱塞推向第二柱塞位置，以及致动器来展开柱塞弹簧。注射器还包括靠近壳体的远端的针，其可从第一针位置移动到第二针位置，以及与壳体耦合的护罩。护罩可在缩回位置和延伸位置之间移动，当延伸位置时护罩围绕针的至少一部分。注射器还包括互锁组件，护罩弹簧和被配置为禁止护罩运动的锁定组件。

2. 发明授权

US5234419A Suction drainage infection control system 失效
标题翻译：吸引排水感染控制系统
公开(公告)号：US5234419A
公开(公告)日：1993-08-10
申请号：US906015
申请日：1992-06-26
申请人： Peter L. Bryant , Richard W. Grabenkort , James F. Middaugh , Timothy J. Oswald , Edward S. Tripp
发明人： Peter L. Bryant , Richard W. Grabenkort , James F. Middaugh , Timothy J. Oswald , Edward S. Tripp
IPC分类号： A61G12/00 , A61F5/44 , A61F5/441 , A61L2/16 , A61M1/00 , B09B1/00
CPC分类号： A61F5/441 , A61M1/0001 , A61M1/0017 , A61M1/0019 , A61M1/0052 , A61M1/0096 , Y10T137/3109 , Y10T137/7433
摘要： A suction drainage control system that reduces an operator's exposure to infectious waste by permitting waste-treating material to be dispersed into a sealed chamber in which the infectious waste is contained. The sealed chamber includes a cover with a flexible liner sealed to and suspended therefrom. A freely movable reservoir is provided inside the sealed chamber for storing the waste-treating material, which reservoir is opened by manipulating the flexible liner to open the reservoir.
摘要翻译：抽吸排水控制系统，其通过允许废物处理材料分散到其中包含感染性废物的密封室中，减少操作者对感染性废物的暴露。密封室包括具有密封并悬挂在其上的柔性衬里的盖。在密封室内部设置有可自由移动的储存器，用于存储废物处理材料，该储存器通过操纵柔性衬垫打开储存器来打开。

3. 发明授权

US5178267A Packaging system for a sterilizable calbratable medical device 失效
标题翻译：可灭菌可压缩医疗器械的包装系统
公开(公告)号：US5178267A
公开(公告)日：1993-01-12
申请号：US631805
申请日：1990-12-20
申请人： Richard W. Grabenkort , Conrad T. O. Fong , Cheryl D. Germany
发明人： Richard W. Grabenkort , Conrad T. O. Fong , Cheryl D. Germany
IPC分类号： A61B5/00 , A61B19/02 , A61L2/20 , A61L2/26 , A61M25/00 , B65D79/02 , B65D81/20
CPC分类号： A61B5/1495 , A61B50/30 , A61B50/33 , A61L2/206 , A61M25/002 , A61B2562/242
摘要： An improved package for a medical device includes an inner wrap that envelopes the medical device, the inner wrap including a gas-permeable surface, and a chamber defined in the inner wrap to store a hydratable sensor of the medical device. Plumbing for the package controls fluid flow into and within the inner wrap, to selectively establish, without breaching a portion of the inner wrap surrounding the sensor, fluid communication between the gas-permeable surface and the sensor, to sterilize the sensor and the inner wrap with a gaseous sterilant, or to hydrate the sensor with hydration fluid obtained from a source of hydration fluid connected to the chamber, or to equilibrate the hydration fluid in the chamber with an external source of gas, to calibrate the sensor within the inner wrap.
摘要翻译：用于医疗装置的改进的包装包括包封医疗装置的内包裹物，内包裹物包括气体可渗透表面，以及限定在内包装中的腔室，以存储医疗装置的可水合传感器。用于包装的管道控制进入内部包裹物内部和流体内部的流体流动，以选择性地建立，而不会破坏围绕传感器的内部包裹物的一部分，在透气表面和传感器之间的流体连通，以消除传感器和内部包装使用气态杀菌剂，或者使用从连接到室的水合流体源获得的水合流体来水合传感器，或者使室内的水合流体与外部气体源平衡，以校准内部涡卷内的传感器。

4. 发明授权

US5143617A In-line moisture filter usable in an improved packaging system for a sterilizable calibratable medical device 失效
标题翻译：可用于可灭菌可校准医疗设备的改进的包装系统中的在线湿度过滤器
公开(公告)号：US5143617A
公开(公告)日：1992-09-01
申请号：US632711
申请日：1990-12-20
申请人： Richard W. Grabenkort
发明人： Richard W. Grabenkort
IPC分类号： A61B5/00 , A61B19/02 , A61L2/20 , A61M25/00
CPC分类号： A61L2/206 , A61B5/1495 , A61B50/30 , A61B50/33 , A61M25/002 , A61B2562/242
摘要： A filter for removing a liquid from a gas comprising a housing, a liquid absorbent material disposed in the housing to absorb the liquid from the gas passing through the filter, and a plurality of ribs disposed on an inner surface of the housing, the ribs spaced apart from each other and supporting the liquid absorbent material within the housing. The ribs define a plurality of open passages around the liquid absorbent material, and connecting an inlet of the housing in fluid communication with an outlet, so that the gas flowing between the inlet and the outlet experiences substantially no pressure drop, the liquid in the gas being absorbed by the liquid absorbent material in the filter, as the gas flows through the filter.
摘要翻译：一种用于从气体中除去液体的过滤器，包括壳体，设置在壳体中以吸收来自穿过过滤器的气体的液体的液体吸收材料，以及设置在壳体的内表面上的多个肋，彼此分开并将液体吸收材料支撑在壳体内。肋限定围绕液体吸收材料的多个开放通道，并且将壳体的入口与出口流体连通地连接，使得在入口和出口之间流动的气体基本上不受压降，气体中的液体当气体流过过滤器时，被过滤器中的液体吸收材料吸收。

5. 发明授权

US5111836A Frangible element valve usable in an improved packaging system for a sterilizable calibratable medical device 失效
标题翻译：可用于可消毒的可校准医疗设备的改进的包装系统中的易碎元件阀
公开(公告)号：US5111836A
公开(公告)日：1992-05-12
申请号：US631859
申请日：1990-12-20
申请人： Richard W. Grabenkort
发明人： Richard W. Grabenkort
IPC分类号： A61B19/02 , F16K17/40
CPC分类号： F16K17/40 , A61B50/30 , F16K13/04 , Y10T137/1632
摘要： A frangible element valve assembly including a housing having an inlet port and an outlet port connected by a fluid passage that extends through the housing; and an actuator selectively controlling fluid flow through the fluid passage being biased to a predetermined fluid flow control position by a spring member of the valve assembly. Frangible elements of the valve assembly oppose the spring member to temporarily prevent the actuator from assuming the predetermined fluid flow control position, and these elements include breakable members that are broken by an operator to allow the actuator to thereafter assume the predetermined fluid flow control position until selectively changed by the operator.
摘要翻译：一种易碎元件阀组件，其包括壳体，该壳体具有通过延伸穿过壳体的流体通道连接的入口端口和出口端口; 并且选择性地控制流过所述流体通道的流体的致动器被所述阀组件的弹簧构件偏置到预定流体流动控制位置。阀组件的易碎元件与弹簧构件相对，以暂时阻止致动器承担预定的流体流量控制位置，并且这些元件包括由操作者破碎的可破坏构件，以允许致动器此后承担预定的流体流动控制位置，直到由操作员有选择地改变。

6. 发明授权

US4863016A Packaging for a sterilizable calibratable medical device 失效
标题翻译：可灭菌可校准医疗器械的包装
公开(公告)号：US4863016A
公开(公告)日：1989-09-05
申请号：US224425
申请日：1988-07-25
申请人： Conrad T. O. Fong , Richard W. Grabenkort , Scott P. Huntley
发明人： Conrad T. O. Fong , Richard W. Grabenkort , Scott P. Huntley
IPC分类号： A61L2/20 , A61B19/02 , A61M25/00
CPC分类号： A61M25/002 , A61B50/30
摘要： The present invention provides a package for and method of packaging a sterilizable calibratable medical device including a hydratable sensor component. The device is maintained in a sterile environment during storage and in a clean environment during the calibration procedure. The package includes a manifold connected to the sensor component by plumbing. The plumbing establishes fluid communication between the manifold and the sensor component and/or between the sensor component and the ambient environment of the plumbing. The manifold, plumbing and medical device are sealed in a wrap including a gas-permeable surface. The wrap and its contents, including the interior surfaces of the components, are sterilizable by exposing the wrap to a gaseous sterilization solution and appropriately adjusting the plumbing. The medical device is hydratable by directing the hydration solution to the sensor component by means of the plumbing. In order to store the package over an extended period of time, a gas-impermeable chamber is defined which includes the ambient environment of the plumbing. The gaseous environment of the medical device is thereby controllable. In this manner, the device is prepared for calibration and is storable in the sterile environment. By connecting a reservoir including calibration solution to the plumbing, the calibration solution is directed to the sensor component without removing the medical device from its clean enviroment. The temperatures of the sensor component and the solution are controlled throughout the calibration process in order to ensure that the device is calibrated in accordance with its intended use. The present invention further discloses a solution for preparing the medical device for use. The solution is chemically compatible with the intended use of the device.

7. 发明授权

US5876372A Syringe system accomodating seperate prefilled barrels for two constituents 失效
标题翻译：注射器系统适用于两种成分的单独预装桶
公开(公告)号：US5876372A
公开(公告)日：1999-03-02
申请号：US916903
申请日：1997-08-21
申请人： Richard W. Grabenkort , John M. Hofstetter , John A. O'Neil
发明人： Richard W. Grabenkort , John M. Hofstetter , John A. O'Neil
IPC分类号： A61M5/31 , A61M5/315 , A61M37/00
CPC分类号： A61M5/31596 , A61M2005/3121 , A61M2005/3128 , A61M2005/31598
摘要： A prefilled, two-constituent system is provided with first and second containers or barrels. The first barrel includes a first chamber having a dispensing end or delivery end. The delivery end defines a dispensing passage or delivery passage communicating through the delivery end to accommodate the dispensing of fluid from the first chamber. A movable seal or reciprocable stopper is slidably disposed in the first chamber, and a first constituent is provided in the first chamber between the delivery end and the stopper. A second container or barrel is sized to be disposed in the first barrel and has a discharge end defining a discharge passage communicating through the discharge end to accommodate the discharge of fluid from the second barrel. A plunger is slidably disposed within the second barrel. A liquid second constituent is provided in the second barrel between the discharge end and the plunger. The first barrel stopper and the second barrel discharge end are engageable directly or indirectly to cooperatively define a coupling accommodating the flow of the liquid second constituent from the second barrel into the first chamber of the first barrel as the second barrel moves outwardly relative to the first chamber.
摘要翻译：预填充的双组分系统设置有第一和第二容器或桶。第一桶包括具有分配端或输送端的第一室。输送端限定分配通道或输送通道，其通过输送端连通以适应来自第一室的流体的分配。可移动的密封件或可往复运动的塞子可滑动地设置在第一腔室中，并且第一构件在第一腔室中设置在输送端和塞子之间。第二容器或筒的尺寸设置成设置在第一筒中，并且具有限定通过排出端连通的排放通道的排放端，以适应来自第二筒的流体的排放。柱塞可滑动地设置在第二筒内。在排出端和柱塞之间的第二筒体中设置液体第二成分。第一筒塞和第二筒排放端可直接或间接地接合，以协作地限定一个联接器，当第二筒相对于第一筒排出端向外移动时，该联接器将液体第二成分从第二筒体的流动容纳到第一桶的第一室中房间。

8. 发明授权

US5779668A Syringe barrel for lyophilization, reconstitution and administration 失效
标题翻译：注射器用于冻干，重组和给药
公开(公告)号：US5779668A
公开(公告)日：1998-07-14
申请号：US620061
申请日：1996-03-21
申请人： Richard W. Grabenkort
发明人： Richard W. Grabenkort
IPC分类号： A61M5/24 , A61M5/31 , A61M5/315 , A61M37/00
CPC分类号： A61M5/31596 , A61M5/3129 , A61M2005/3104 , A61M2005/3106 , A61M2005/3123 , A61M2005/3128 , A61M2005/31598 , A61M5/3135
摘要： The syringe system of the present invention includes a first or primary syringe barrel having a substantially closed end defining a delivery passage and an opposite open end. A removable closure seals the delivery passage of the first syringe barrel so as to define a container for containing a medical solution. A plurality of longitudinal channels are positioned on the inner surface of an enlarged diameter venting portion of the syringe barrel at the open end. A reciprocable stopper is provided for sealing the open end of the barrel so that the reciprocable stopper has a first position abutting the channels of the inner surface of the barrel so as to allow the medical solution to be lyophilized through the channels. The reciprocable stopper can then be longitudinally moved to a second position in the barrel in the in the direction of the delivery passage and beyond the channels to seal the lyophilized drug within the barrel.
摘要翻译：本发明的注射器系统包括具有限定输送通道和相对的开口端的基本封闭端的第一或主注射器筒。可拆卸的封闭件密封第一注射器筒的输送通道，以便限定用于容纳医用溶液的容器。多个纵向通道在开口端位于注射器筒的扩大直径排气部分的内表面上。提供可往复运动的止动件用于密封筒的开口端，使得往复式止动器具有与筒的内表面的通道邻接的第一位置，以允许医用溶液通过通道被冻干。然后可往复运动的止动器沿着输送通道的方向纵向地移动到筒体中的第二位置，并且超过通道以密封桶内的冻干药物。

9. 发明授权

US5682874A System for connecting an inhalation agent container to a vaporizer 失效
标题翻译：将吸入剂容器连接到蒸发器的系统
公开(公告)号：US5682874A
公开(公告)日：1997-11-04
申请号：US408461
申请日：1995-03-22
申请人： Richard W. Grabenkort , Sheldon M. Wecker
发明人： Richard W. Grabenkort , Sheldon M. Wecker
IPC分类号： A61M16/18 , A61M11/00 , A61M16/00 , A62B9/04 , C08B3/00
CPC分类号： A61M16/183
摘要： A reusable connector is provided for mounting on an anesthetic vaporizer to connect the vaporizer with an anaesthetic container and hold the container in an inverted orientation. Cooperating engaging structures are employed to pull the container and connector together. In a preferred form, the container has a closure defining at least one port occluded by a recessed, pierceable membrane. A screw thread is provided on the container. The connector has a base provided with a first coupling for connecting the base to the vaporizer. The base has a second coupling that includes plug adapted to be connected to the container closure, The base also defines a passage extending from the plug through the first coupling for communicating with the vaporizer, The plug includes at least one projecting conduit that communicates with the passage and that defines a piercing tip for entering into the port to pierce the membrane, A collar is mounted for rotation on the base, The collar engages the base and defines a screw thread for engaging the thread on the container to pull the container onto the plug as the membrane is pierced.
摘要翻译：提供了可重复使用的连接器，用于安装在麻醉蒸发器上以将蒸发器与麻醉容器连接并以反方向保持容器。采用合作的接合结构将容器和连接器拉到一起。在优选形式中，容器具有限定由凹陷的可刺破膜遮蔽的至少一个端口的封闭件。在容器上设有螺纹。连接器具有设置有用于将基座连接到蒸发器的第一联接器的基座。基座具有第二联接器，其包括适于连接到容器封闭件的塞子。底座还限定从塞子延伸穿过第一联接器以与蒸发器连通的通道。塞子包括至少一个突出导管，其与通道，并且其限定了用于进入端口以刺穿膜的穿刺尖端。安装用于在基座上旋转的套环。套环接合基部并且限定用于接合容器上的线的螺纹，以将容器拉到塞子当膜被刺穿时。

10. 发明授权

US5566729A Drug reconstitution and administration system 失效
标题翻译：药物重组管理制度
公开(公告)号：US5566729A
公开(公告)日：1996-10-22
申请号：US417575
申请日：1995-04-06
申请人： Richard W. Grabenkort , John C. Tanner, II , Sheldon M. Wecker
发明人： Richard W. Grabenkort , John C. Tanner, II , Sheldon M. Wecker
IPC分类号： A61J1/00 , A61J1/20 , B65B1/04 , B65B3/04 , B65B31/00
CPC分类号： A61J1/2096 , A61J1/2089 , A61J1/2041 , A61J1/2065 , Y10S604/905
摘要： A drug reconstitution and administration system includes a container for a concentrated drug or other medicament, a syringe assembly which can be pre-filled with a liquid diluent, and a mixing adapter assembly which facilitates mixing of the medicament with the liquid diluent. The adapter assembly includes inner and outer concentrically arranged, relatively movable sleeves, which together define an expandable mixing chamber within the adapter assembly. The container and pre-filled syringe are respectively fitted to the adapter assembly, with the contents of the container and the contents of the syringe transferred into the internal mixing chamber. A diluted drug mixture is formed in the mixing chamber, and the mixture is transferred into the syringe assembly for subsequent patient administration.
摘要翻译：药物重建和给药系统包括用于浓缩药物或其它药物的容器，可预先填充有液体稀释剂的注射器组件以及促进药物与液体稀释剂混合的混合适配器组件。适配器组件包括内部和外部同心布置的相对可移动的套筒，其一起限定适配器组件内的可扩张混合室。容器和预装注射器分别装配到适配器组件上，容器的内容物和注射器的内容物转移到内部混合室中。在混合室中形成稀释的药物混合物，并将混合物转移到注射器组件中以供随后的患者给药。

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