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1. 发明授权

US08246630B2 Apparatus and method for injecting fluent material at a distracted tissue site 有权
标题翻译：在分散的组织部位注射流体物质的装置和方法
公开(公告)号：US08246630B2
公开(公告)日：2012-08-21
申请号：US12858530
申请日：2010-08-18
申请人： Richard Manzi , Tyler Lipschultz , Peter Barreiro , Mark LoGuidice , Thomas Wilson , Steve Wysocki
发明人： Richard Manzi , Tyler Lipschultz , Peter Barreiro , Mark LoGuidice , Thomas Wilson , Steve Wysocki
IPC分类号： A61F2/44
CPC分类号： A61B17/8811 , A61B17/70 , A61B17/8852
摘要： A system and method is provided for distracting opposite surfaces from the interior of a bone, such as a vertebral body. A working channel cannula provides a working channel through which an inserter and an injection cannula can simultaneously pass. The inserter transports a plurality of wafers into the interior of the bone to form a load-bearing stack bearing against the opposite surfaces. The injection cannula is used to inject a fluent material into and/or around the stack. In certain embodiments, the fluent material is a load-bearing or hardenable material, such as bone cement. In other embodiments, the fluent material can be a BMP, HAP, or other osteo-inductive, osteo-conductive, or pharmaceutical compositions. A syringe containing the fluent material is engaged to the injection cannula and is operable to inject the fluent material into the vertebral body under controlled pressure.
摘要翻译：提供了一种系统和方法，用于从骨骼的内部（例如椎体）分散相对表面。工作通道套管提供工作通道，插入器和注射套管可以通过该工作通道同时通过。插入器将多个晶片传送到骨的内部以形成抵靠相对表面的承载堆叠轴承。注射套管用于将流体材料注入到堆叠中和/或周围。在某些实施方案中，流动材料是承载或可硬化材料，例如骨粘固剂。在其它实施方案中，流感材料可以是BMP，HAP或其它骨诱导性，骨诱导性或药物组合物。含有流动材料的注射器与注射套管接合并且可操作以在受控的压力下将流体材料注入椎体中。

2. 发明授权

US08197544B1 Method for distracting opposing vertebral bodies of a spine 有权
标题翻译：分散脊柱相对椎体的方法
公开(公告)号：US08197544B1
公开(公告)日：2012-06-12
申请号：US13406073
申请日：2012-02-27
申请人： Richard Manzi , Tyler Lipschultz , Peter Barreiro , Mark LoGuidice , Thomas Wilson , Steve Wysocki
发明人： Richard Manzi , Tyler Lipschultz , Peter Barreiro , Mark LoGuidice , Thomas Wilson , Steve Wysocki
IPC分类号： A61B17/58
CPC分类号： A61B17/8811 , A61B17/70 , A61B17/8852
摘要： A system and method is provided for distracting opposite surfaces from the interior of a bone, such as a vertebral body. A working channel cannula provides a working channel through which an inserter and an injection cannula can simultaneously pass. The inserter transports a plurality of wafers into the interior of the bone to form a load-bearing stack bearing against the opposite surfaces. The injection cannula is used to inject a fluent material into and/or around the stack. In certain embodiments, the fluent material is a load-bearing or hardenable material, such as bone cement. In other embodiments, the fluent material can be a BMP, HAP, or other osteo-inductive, osteo-conductive, or pharmaceutical compositions. A syringe containing the fluent material is engaged to the injection cannula and is operable to inject the fluent material into the vertebral body under controlled pressure.
摘要翻译：提供了一种系统和方法，用于从骨骼的内部（例如椎体）分散相对表面。工作通道套管提供工作通道，插入器和注射套管可以通过该工作通道同时通过。插入器将多个晶片传送到骨的内部以形成抵靠相对表面的承载堆叠轴承。注射套管用于将流体材料注入到堆叠中和/或周围。在某些实施方案中，流动材料是承载或可硬化材料，例如骨粘固剂。在其它实施方案中，流感材料可以是BMP，HAP或其它骨诱导性，骨诱导性或药物组合物。含有流动材料的注射器与注射套管接合并且可操作以在受控的压力下将流体材料注入椎体中。

3. 发明申请

US20120158067A1 METHOD FOR DISTRACTING OPPOSING VERTEBRAL BODIES OF A SPINE 有权
标题翻译：用于分离对角螺旋体的方法
公开(公告)号：US20120158067A1
公开(公告)日：2012-06-21
申请号：US13406073
申请日：2012-02-27
申请人： Richard Manzi , Tyler Lipschultz , Peter Barreiro , Mark D. LoGuidice , Thomas Wilson , Steve Wysocki
发明人： Richard Manzi , Tyler Lipschultz , Peter Barreiro , Mark D. LoGuidice , Thomas Wilson , Steve Wysocki
IPC分类号： A61B17/88
CPC分类号： A61B17/8811 , A61B17/70 , A61B17/8852
摘要： A system and method is provided for distracting opposite surfaces from the interior of a bone, such as a vertebral body. A working channel cannula provides a working channel through which an inserter and an injection cannula can simultaneously pass. The inserter transports a plurality of wafers into the interior of the bone to form a load-bearing stack bearing against the opposite surfaces. The injection cannula is used to inject a fluent material into and/or around the stack. In certain embodiments, the fluent material is a load-bearing or hardenable material, such as bone cement. In other embodiments, the fluent material can be a BMP, HAP, or other osteo-inductive, osteo-conductive, or pharmaceutical compositions. A syringe containing the fluent material is engaged to the injection cannula and is operable to inject the fluent material into the vertebral body under controlled pressure.
摘要翻译：提供了一种系统和方法，用于从骨骼的内部（例如椎体）分散相对表面。工作通道套管提供工作通道，插入器和注射套管可以通过该工作通道同时通过。插入器将多个晶片传送到骨的内部以形成抵靠相对表面的承载堆叠轴承。注射套管用于将流体材料注入到堆叠中和/或周围。在某些实施方案中，流动材料是承载或可硬化材料，例如骨粘固剂。在其它实施方案中，流感材料可以是BMP，HAP或其它骨诱导性，骨诱导性或药物组合物。含有流动材料的注射器与注射套管接合并且可操作以在受控的压力下将流体材料注入椎体中。

4. 发明授权

US07875078B2 Expandable interbody fusion device 有权
标题翻译：可扩展体间融合装置
公开(公告)号：US07875078B2
公开(公告)日：2011-01-25
申请号：US11211347
申请日：2005-08-25
申请人： Steve Wysocki , Joseph N. Logan , Richard Manzi , Robert D. Paxson , John Pafford , Mark D. LoGuidice , Tyler P. Lipschultz , Carl Michael Nilsson , Daniel S. Savage
发明人： Steve Wysocki , Joseph N. Logan , Richard Manzi , Robert D. Paxson , John Pafford , Mark D. LoGuidice , Tyler P. Lipschultz , Carl Michael Nilsson , Daniel S. Savage
IPC分类号： A61F2/44
CPC分类号： A61F2/447 , A61B2017/0256 , A61F2/442 , A61F2/4425 , A61F2/4455 , A61F2/4465 , A61F2/4611 , A61F2002/30383 , A61F2002/30476 , A61F2002/30492 , A61F2002/3052 , A61F2002/30556 , A61F2002/30599 , A61F2002/30601 , A61F2002/30904 , A61F2002/448 , A61F2220/0025 , A61F2250/0009 , A61F2250/0063
摘要： An expandable interbody fusion device for implantation into the intradiscal space between two opposing vertebral bodies of a spine comprises a superior endplate member having an upper surface for engaging a superior vertebral body in a spine, and an inferior endplate member having a lower surface for engaging an inferior vertebral body in the spine. The superior endplate member and the inferior endplate member are releasably coupled and define a cavity therebetween. At least one expansion member is configured to be introduced into the cavity to move the superior endplate and the inferior endplate members relatively apart upon introduction and to thereby decouple the superior endplate member and the inferior endplate member. An inserter may be releasably coupled to the device to facilitate insertion of the device as well as to provide a track for insertion of the expansion members.
摘要翻译：用于植入脊柱的两个相对椎体之间的椎间盘内空间的可扩展的椎体间融合装置包括具有用于与脊柱中的上椎体接合的上表面的上端板构件，以及具有下表面的下端板构件脊椎下椎体。上端板构件和下端板构件可释放地联接并且在它们之间限定空腔。至少一个膨胀构件被构造成引入空腔中，以在引入时使上端板和下端板构件相对分开，从而使上端板构件和下端板构件分离。插入器可以可释放地联接到装置以便于装置的插入以及提供用于插入扩张构件的轨道。

5. 发明申请

US20050182414A1 Apparatus and method for injecting fluent material at a distracted tissue site 有权
标题翻译：在分散的组织部位注射流体物质的装置和方法
公开(公告)号：US20050182414A1
公开(公告)日：2005-08-18
申请号：US11031562
申请日：2005-01-07
申请人： Richard Manzi , Tyler Lipschultz , Peter Barreiro , Mark LoGuidice , Thomas Wilson , Steve Wysocki
发明人： Richard Manzi , Tyler Lipschultz , Peter Barreiro , Mark LoGuidice , Thomas Wilson , Steve Wysocki
IPC分类号： A61B17/56 , A61B17/58 , A61B17/88
CPC分类号： A61B17/8811 , A61B17/70 , A61B17/8852
摘要： A system and method is provided for distracting opposite surfaces from the interior of a bone, such as a vertebral body. A working channel cannula provides a working channel through which an inserter and an injection cannula can simultaneously pass. The inserter transports a plurality of wafers into the interior of the bone to form a load-bearing stack bearing against the opposite surfaces. The injection cannula is used to inject a fluent material into and/or around the stack. In certain embodiments, the fluent material is a load-bearing or hardenable material, such as bone cement. In other embodiments, the fluent material can be a BMP, HAP, or other osteo-inductive, osteo-conductive, or pharmaceutical compositions. A syringe containing the fluent material is engaged to the injection cannula and is operable to inject the fluent material into the vertebral body under controlled pressure.
摘要翻译：提供了一种系统和方法，用于从骨骼的内部（例如椎体）分散相对表面。工作通道套管提供工作通道，插入器和注射套管可以通过该工作通道同时通过。插入器将多个晶片传送到骨的内部以形成抵靠相对表面的承载堆叠轴承。注射套管用于将流体材料注入到堆叠中和/或周围。在某些实施方案中，流动材料是承载或可硬化材料，例如骨粘固剂。在其它实施方案中，流感材料可以是BMP，HAP或其它骨诱导性，骨诱导性或药物组合物。含有流动材料的注射器与注射套管接合并且可操作以在受控的压力下将流体材料注入椎体中。

6. 发明申请

US20120316568A1 SYSTEM FOR DISTRACTING OPPOSING VERTEBRAL BODIES OF A SPINE 有权
标题翻译：用于分离对位椎体的椎体的系统
公开(公告)号：US20120316568A1
公开(公告)日：2012-12-13
申请号：US13587283
申请日：2012-08-16
申请人： Richard Manzi , Tyler Lipschultz , Peter Barreiro , Mark D. LoGuidice , Thomas Wilson , Steve Wysocki
发明人： Richard Manzi , Tyler Lipschultz , Peter Barreiro , Mark D. LoGuidice , Thomas Wilson , Steve Wysocki
IPC分类号： A61B17/66
CPC分类号： A61B17/8811 , A61B17/70 , A61B17/8852
摘要： A system and method is provided for distracting opposite surfaces from the interior of a bone, such as a vertebral body. A working channel cannula provides a working channel through which an inserter and an injection cannula can simultaneously pass. The inserter transports a plurality of wafers into the interior of the bone to form a load-bearing stack bearing against the opposite surfaces. The injection cannula is used to inject a fluent material into and/or around the stack. In certain embodiments, the fluent material is a load-bearing or hardenable material, such as bone cement. In other embodiments, the fluent material can be a BMP, HAP, or other osteo-inductive, osteo-conductive, or pharmaceutical compositions. A syringe containing the fluent material is engaged to the injection cannula and is operable to inject the fluent material into the vertebral body under controlled pressure.
摘要翻译：提供了一种系统和方法，用于从骨骼的内部（例如椎体）分散相对表面。工作通道套管提供工作通道，插入器和注射套管可以通过该工作通道同时通过。插入器将多个晶片传送到骨的内部以形成抵靠相对表面的承载堆叠轴承。注射套管用于将流体材料注入到堆叠中和/或周围。在某些实施方案中，流动材料是承载或可硬化材料，例如骨粘固剂。在其它实施方案中，流感材料可以是BMP，HAP或其它骨诱导性，骨诱导性或药物组合物。含有流动材料的注射器与注射套管接合并且可操作以在受控的压力下将流体材料注入椎体中。

7. 发明申请

US20110004217A1 Apparatus and Method for Injecting Fluent Material at a Distracted Tissue Site 有权
标题翻译：在分散的组织部位注射流体物质的装置和方法
公开(公告)号：US20110004217A1
公开(公告)日：2011-01-06
申请号：US12858530
申请日：2010-08-18
申请人： RIchard Manzi , Tyler Lipschultz , Peter Barreiro , Mark D. LoGuidice , Thomas Wilson , Steve Wysocki
发明人： RIchard Manzi , Tyler Lipschultz , Peter Barreiro , Mark D. LoGuidice , Thomas Wilson , Steve Wysocki
IPC分类号： A61B17/66
CPC分类号： A61B17/8811 , A61B17/70 , A61B17/8852
摘要： A system and method is provided for distracting opposite surfaces from the interior of a bone, such as a vertebral body. A working channel cannula provides a working channel through which an inserter and an injection cannula can simultaneously pass. The inserter transports a plurality of wafers into the interior of the bone to form a load-bearing stack bearing against the opposite surfaces. The injection cannula is used to inject a fluent material into and/or around the stack. In certain embodiments, the fluent material is a load-bearing or hardenable material, such as bone cement. In other embodiments, the fluent material can be a BMP, HAP, or other osteo-inductive, osteo-conductive, or pharmaceutical compositions. A syringe containing the fluent material is engaged to the injection cannula and is operable to inject the fluent material into the vertebral body under controlled pressure.
摘要翻译：提供了一种系统和方法，用于从骨骼的内部（例如椎体）分散相对表面。工作通道套管提供工作通道，插入器和注射套管可以通过该工作通道同时通过。插入器将多个晶片传送到骨的内部以形成抵靠相对表面的承载堆叠轴承。注射套管用于将流体材料注入到堆叠中和/或周围。在某些实施方案中，流动材料是承载或可硬化材料，例如骨粘固剂。在其它实施方案中，流感材料可以是BMP，HAP或其它骨诱导性，骨诱导性或药物组合物。含有流动材料的注射器与注射套管接合并且可操作以在受控的压力下将流体材料注入椎体中。

8. 发明授权

US07789912B2 Apparatus and method for injecting fluent material at a distracted tissue site 有权
标题翻译：在分散的组织部位注射流体物质的装置和方法
公开(公告)号：US07789912B2
公开(公告)日：2010-09-07
申请号：US11031562
申请日：2005-01-07
申请人： Richard Manzi , Tyler Lipschultz , Peter Barreiro , Mark D. LoGuidice , Thomas Wilson , Steve Wysocki
发明人： Richard Manzi , Tyler Lipschultz , Peter Barreiro , Mark D. LoGuidice , Thomas Wilson , Steve Wysocki
IPC分类号： A61B17/58
CPC分类号： A61B17/8811 , A61B17/70 , A61B17/8852
摘要： A system and method is provided for distracting opposite surfaces from the interior of a bone, such as a vertebral body. A working channel cannula provides a working channel through which an inserter and an injection cannula can simultaneously pass. The inserter transports a plurality of wafers into the interior of the bone to form a load-bearing stack bearing against the opposite surfaces. The injection cannula is used to inject a fluent material into and/or around the stack. In certain embodiments, the fluent material is a load-bearing or hardenable material, such as bone cement. In other embodiments, the fluent material can be a BMP, HAP, or other osteo-inductive, osteo-conductive, or pharmaceutical compositions. A syringe containing the fluent material is engaged to the injection cannula and is operable to inject the fluent material into the vertebral body under controlled pressure.
摘要翻译：提供了一种系统和方法，用于从骨骼的内部（例如椎体）分散相对表面。工作通道套管提供工作通道，插入器和注射套管可以通过该工作通道同时通过。插入器将多个晶片传送到骨的内部以形成抵靠相对表面的承载堆叠轴承。注射套管用于将流体材料注入到堆叠中和/或周围。在某些实施方案中，流动材料是承载或可硬化材料，例如骨粘固剂。在其它实施方案中，流感材料可以是BMP，HAP或其它骨诱导性，骨诱导性或药物组合物。含有流动材料的注射器与注射套管接合并且可操作以在受控的压力下将流体材料注入椎体中。

9. 发明申请

US20060229629A1 Tissue distraction device 有权
标题翻译：组织牵引装置
公开(公告)号：US20060229629A1
公开(公告)日：2006-10-12
申请号：US11353711
申请日：2006-02-13
申请人： Richard Manzi , Joseph Logan , Steven Wysocki , Frank Bono , Spanky Raymond
发明人： Richard Manzi , Joseph Logan , Steven Wysocki , Frank Bono , Spanky Raymond
IPC分类号： A61B17/58
CPC分类号： A61B17/8852 , A61B17/025 , A61B17/1285 , A61B2017/0256 , A61F2/4455
摘要： An apparatus and method for distracting, in a given direction, and supporting two tissue surfaces is provided. A plurality of wafers are consecutively inserted using a wafer insertion apparatus between the two tissue surfaces to create a column of wafers. A detachable wafer assembly is provided that includes a base wafer initially associated with a track assembly of a wafer insertion apparatus. The base wafer is dislodged from the track assembly so that the base wafer is left within the distraction site as the track assembly is removed. A top cap wafer is provided that is situated at the top of the wafer stack, in which the top cap wafer is larger than the remaining wafers to form a gap surrounding the stack to receive biologic material.
摘要翻译：提供了一种用于在给定方向上分散并支撑两个组织表面的装置和方法。使用在两个组织表面之间的晶片插入装置连续地插入多个晶片以产生晶片列。提供了一种可拆卸的晶片组件，其包括最初与晶片插入装置的轨道组件相关联的基底晶片。底座晶片从轨道组件移出，使得当轨道组件被移除时，基底晶片留在牵引位置内。提供顶盖晶片，其位于晶片堆叠的顶部，其中顶盖晶片大于其余晶片，以形成围绕堆叠以接收生物材料的间隙。

10. 发明申请

US20060058880A1 Expandable interbody fusion device 有权
标题翻译：可扩展体间融合装置
公开(公告)号：US20060058880A1
公开(公告)日：2006-03-16
申请号：US11211347
申请日：2005-08-25
申请人： Steve Wysocki , Joseph Logan , Richard Manzi , Robert Paxson , John Pafford , Mark LoGuidice , Tyler Lipschultz , Carl Nilsson , Daniel Savage
发明人： Steve Wysocki , Joseph Logan , Richard Manzi , Robert Paxson , John Pafford , Mark LoGuidice , Tyler Lipschultz , Carl Nilsson , Daniel Savage
IPC分类号： A61F2/44 , A61B17/88 , A61F2/46
CPC分类号： A61F2/447 , A61B2017/0256 , A61F2/442 , A61F2/4425 , A61F2/4455 , A61F2/4465 , A61F2/4611 , A61F2002/30383 , A61F2002/30476 , A61F2002/30492 , A61F2002/3052 , A61F2002/30556 , A61F2002/30599 , A61F2002/30601 , A61F2002/30904 , A61F2002/448 , A61F2220/0025 , A61F2250/0009 , A61F2250/0063
摘要： An expandable interbody fusion device for implantation into the intradiscal space between two opposing vertebral bodies of a spine comprises a superior endplate member having an upper surface for engaging a superior vertebral body in a spine, and an inferior endplate member having a lower surface for engaging an inferior vertebral body in the spine. The superior endplate member and the inferior endplate member are releasably coupled and define a cavity therebetween. At least one expansion member is configured to be introduced into the cavity to move the superior endplate and the inferior endplate members relatively apart upon introduction and to thereby decouple the superior endplate member and the inferior endplate member. An inserter may be releasably coupled to the device to facilitate insertion of the device as well as to provide a track for insertion of the expansion members.
摘要翻译：用于植入脊柱的两个相对椎体之间的椎间盘内空间的可扩展的椎体间融合装置包括具有用于与脊柱中的上椎体接合的上表面的上端板构件，以及具有下表面的下端板构件脊椎下椎体。上端板构件和下端板构件可释放地联接并且在它们之间限定空腔。至少一个膨胀构件被构造成引入空腔中，以在引入时使上端板和下端板构件相对分开，从而使上端板构件和下端板构件分离。插入器可以可释放地联接到装置以便于装置的插入以及提供用于插入扩张构件的轨道。

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