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    • 1. 发明授权
    • Oral care regimen
    • 口腔护理方案
    • US08501161B2
    • 2013-08-06
    • US11745158
    • 2007-05-07
    • Michael PrencipeIsabelle Van RyckeRichard Lovell
    • Michael PrencipeIsabelle Van RyckeRichard Lovell
    • A61K8/00
    • A61K8/25A61K2800/28A61K2800/412A61K2800/88A61K2800/884A61Q11/00
    • The invention includes methods of cleaning an oral surface, maintaining oral health and/or increasing oral health. Such methods encompass contacting an oral surface with a primary oral care composition at least once daily, and contacting the oral surface with a periodic oral care composition at least once within a period of about 42 days. The periodic oral care compositions suitable for use in the method comprise a first abrasive having an Einlehner hardness of greater than about 5 mg loss per 100,000 revolutions and a second abrasive having an Einlehner hardness of less than about 5 mg loss per 100,000 revolutions. In the periodic oral care compositions, the ratio of the first abrasive to the second abrasive is about 1:1.6 to about 1.6:1. The periodic oral care compositions are characterized by a pellicle cleaning ratio of greater than about 100 and a radioactive dentin abrasion of less than about 200. Additionally or alternatively, the methods may include those where the second abrasive comprises silica and has an oil of absorption of greater than about 90 cm3/100 g and/or an Einlehner hardness of less than about 5 mg loss per 100,000 revolutions. The ratio of the first abrasive to the second abrasive may be about 1:1.6 to about 1.6:1. The total amount of the first and second abrasives present in the oral composition may be greater than about 25% by weight of the composition and/or the oral composition has a pellicle cleaning ratio of greater than about 100 and a radioactive dentin abrasion of less than about 200.
    • 本发明包括清洁口腔表面,维持口腔健康和/或增加口腔健康的方法。 这样的方法包括使口腔表面与初级口腔护理组合物每天至少接触一次接触,并在约42天的时间内将口腔表面与周期性口腔护理组合物接触至少一次。 适用于该方法的定期口腔护理组合物包括具有大于约5毫克损失/ 100,000次旋转的爱因纳氏硬度的第一研磨剂,以及每100,000次旋转具有小于约5毫克损失的爱因纳氏硬度的第二磨料。 在定期口腔护理组合物中,第一研磨剂与第二研磨剂的比例为约1:1.6至约1.6:1。 定期口腔护理组合物的特征在于大于约100的防护薄膜清洁率和小于约200的放射性牙本质磨损。另外或替代地,所述方法可以包括其中第二磨料包含二氧化硅并具有吸收油的那些 大于约90cm 3 / 100g和/或Einlehner硬度,每100,000次旋转损失小于约5mg。 第一研磨剂与第二研磨剂的比例可以为约1:1.6至约1.6:1。 存在于口腔组合物中的第一和第二研磨剂的总量可以大于组合物的约25重量%,和/或口腔组合物具有大于约100的防护薄膜清洁率和低于约100的放射性牙本质磨损 约200。
    • 4. 发明申请
    • Oral Care Regimen
    • 口腔护理方案
    • US20070286820A1
    • 2007-12-13
    • US11745158
    • 2007-05-07
    • Michael PrencipeIsabelle RyckeRichard Lovell
    • Michael PrencipeIsabelle RyckeRichard Lovell
    • A61K8/18A61Q11/00
    • A61K8/25A61K2800/28A61K2800/412A61K2800/88A61K2800/884A61Q11/00
    • The invention includes methods of cleaning an oral surface, maintaining oral health and/or increasing oral health. Such methods encompass contacting an oral surface with a primary oral care composition at least once daily, and contacting the oral surface with a periodic oral care composition at least once within a period of about 42 days. The periodic oral care compositions suitable for use in the method comprise a first abrasive having an Einlehner hardness of greater than about 5 mg loss per 100,000 revolutions and a second abrasive having an Einlehner hardness of less than about 5 mg loss per 100,000 revolutions. In the periodic oral care compositions, the ratio of the first abrasive to the second abrasive is about 1:1.6 to about 1.6:1. The periodic oral care compositions are characterized by a pellicle cleaning ratio of greater than about 100 and a radioactive dentin abrasion of less than about 200. Additionally or alternatively, the methods may include those where the second abrasive comprises silica and has an oil of absorption of greater than about 90 cm3/100 g and/or an Einlehner hardness of less than about 5 mg loss per 100,000 revolutions. The ratio of the first abrasive to the second abrasive may be about 1:1.6 to about 1.6:1. The total amount of the first and second abrasives present in the oral composition may be greater than about 25% by weight of the composition and/or the oral composition has a pellicle cleaning ratio of greater than about 100 and a radioactive dentin abrasion of less than about 200.
    • 本发明包括清洁口腔表面,维持口腔健康和/或增加口腔健康的方法。 这样的方法包括使口腔表面与初级口腔护理组合物每天至少接触一次接触,并在约42天的时间内将口腔表面与周期性口腔护理组合物接触至少一次。 适用于该方法的定期口腔护理组合物包括具有大于约5毫克损失/ 100,000次旋转的爱因纳氏硬度的第一研磨剂,以及每100,000次旋转具有小于约5毫克损失的爱因纳氏硬度的第二磨料。 在定期口腔护理组合物中,第一研磨剂与第二研磨剂的比例为约1:1.6至约1.6:1。 定期口腔护理组合物的特征在于大于约100的防护薄膜清洁率和小于约200的放射性牙本质磨损。另外或替代地,所述方法可以包括其中第二磨料包含二氧化硅并具有吸收油的那些 大于约90cm 3 / 100g和/或Einlehner硬度小于每10万次旋转约5mg的损失。 第一研磨剂与第二研磨剂的比例可以为约1:1.6至约1.6:1。 存在于口腔组合物中的第一和第二研磨剂的总量可以大于组合物的约25重量%,和/或口腔组合物具有大于约100的防护薄膜清洁率和低于约100的放射性牙本质磨损 约200。
    • 7. 发明申请
    • Casing hanger annulus monitoring system
    • 套管吊环环形监测系统
    • US20050121199A1
    • 2005-06-09
    • US11029752
    • 2005-01-05
    • Alfred MassieHarry MooreRichard LovellKevin BuckleJohn Osborne
    • Alfred MassieHarry MooreRichard LovellKevin BuckleJohn Osborne
    • E21B33/035E21B33/076
    • E21B33/076E21B33/035
    • A subsea wellhead assembly has the capabilities of communicating from a tree assembly mounted on an inner wellhead housing to a casing annulus. A passage in the wellhead assembly extends within the bore of the wellhead housing from the casing annulus to the tree assembly. A portion of the passage is located within a casing hanger. The passage is opened and closed by a valve. The valve does not open the passage until the tree assembly is connected to the wellhead housing and a tubing hanger orientation sleeve lands in the wellhead assembly. The tubing hanger orientation sleeve actuates the valve when it lands to open the passage. When the passage is opened, the casing annulus is in fluid communication with the interior surface of the wellhead housing, which is in communication with the tree assembly. The valve can be located in the casing hanger, or in a bridging hanger
    • 海底井口组件具有从安装在内部井口壳体上的树组件与套管环通信的能力。 井口组件中的通道在井口壳体的孔内从套管环延伸到树组件。 通道的一部分位于套管架内。 通道由阀门打开和关闭。 在树组件连接到井口壳体之前,阀不打开通道,并且管道悬挂器定向套筒位于井口组件中。 管道悬挂器定向套筒当它着陆以打开通道时致动阀门。 当通道打开时,套管环与与树组件连通的井口壳体的内表面流体连通。 阀门可以位于套管悬挂器中,也可以位于桥式吊架中