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1. 发明授权

US5020516A Circulatory assist method and apparatus 失效
标题翻译：循环辅助方法和装置
公开(公告)号：US5020516A
公开(公告)日：1991-06-04
申请号：US175810
申请日：1988-03-31
申请人： James W. Biondi , Richard A. Mentelos
发明人： James W. Biondi , Richard A. Mentelos
IPC分类号： A61H23/04 , A61H31/00 , A61M1/10 , A61M16/00
CPC分类号： A61H31/005 , A61H31/006 , A61H9/0078 , A61H2201/0103 , A61H2201/1238 , A61H2201/165 , A61H2201/5007 , A61H2201/5043 , A61H2230/207 , A61H2230/25 , A61M1/1067 , A61M16/0096 , A61M2230/04 , A61M2230/435
摘要： Improved cardiocirculatory assistance is provided to a patient by detecting the onset of ventricular ejection in the cardiac cycle of the patient and selectively increasing intrathoracic pressure of the patient in relative phase with respect to the onset of ventricular ejection. Cardiocirculatory output may be monitored and the relative phase of the increase in intrathoracic pressure with respect to the onset of ventricular ejection adjusted to maximize cardiac output. The intrathoracic pressure is increased once every N cardiac cycles where N is a positive integer. The patient interface may include apparatus for supplying high frequency respiration pulses in synchronism with the cardiac cycle. Alternately, or in addition, the pulses may be used to inflate a bladder in contact with the thorax.
摘要翻译：通过检测患者的心脏周期中的心室射血的发作，并且相对于心室射血的开始在相对相位中选择性地增加患者的胸内压力，向患者提供改进的心脏循环辅助。可以监测心脏循环输出，并调节相对于心室射血发作的胸内压升高的相对相位，以使心输出量最大化。每N个心动周期，其中N是正整数，胸内压力增加一次。患者界面可以包括用于与心动周期同步地提供高频呼吸脉冲的装置。或者或另外，脉冲可以用于使与胸部接触的膀胱膨胀。

2. 发明授权

US07818058B2 Automated ECG lead impedance measurement integrated into ECG gating circuitry 有权
标题翻译：自动ECG导联阻抗测量集成到ECG门控电路中
公开(公告)号：US07818058B2
公开(公告)日：2010-10-19
申请号：US11509928
申请日：2006-08-25
申请人： Richard A. Mentelos
发明人： Richard A. Mentelos
IPC分类号： A61N1/00
CPC分类号： A61B5/0424 , A61B5/053 , A61B5/6843 , A61B5/7285 , A61B6/541 , A61B8/543 , A61N1/3925 , A61N2001/083
摘要： The present invention relates to a system and method for determining the impedance of an electrode at the electrode-body interface. The electrode-body impedance of one of the electrodes may be calculated using the voltage difference between that electrode and a plurality of other electrodes, and the voltage and impedance of an alternating current generator in communication with the electrodes.
摘要翻译：本发明涉及一种用于确定电极 - 主体界面处电极阻抗的系统和方法。可以使用该电极和多个其他电极之间的电压差以及与电极连通的交流发电机的电压和阻抗来计算电极之一的电极体阻抗。

3. 发明申请

US20080051845A1 Automated ECG lead impedance measurement integrated into ECG gating circuitry 有权
标题翻译：自动ECG导联阻抗测量集成到ECG门控电路中
公开(公告)号：US20080051845A1
公开(公告)日：2008-02-28
申请号：US11509928
申请日：2006-08-25
申请人： Richard A. Mentelos
发明人： Richard A. Mentelos
IPC分类号： A61N1/00
CPC分类号： A61B5/0424 , A61B5/053 , A61B5/6843 , A61B5/7285 , A61B6/541 , A61B8/543 , A61N1/3925 , A61N2001/083
摘要： The present invention relates to a system and method for determining the impedance of an electrode at the electrode-body interface. The electrode-body impedance of one of the electrodes may be calculated using the voltage difference between that electrode and a plurality of other electrodes, and the voltage and impedance of an alternating current generator in communication with the electrodes.
摘要翻译：本发明涉及一种用于确定电极 - 主体界面处电极阻抗的系统和方法。可以使用该电极和多个其他电极之间的电压差以及与电极连通的交流发电机的电压和阻抗来计算电极之一的电极体阻抗。

4. 发明授权

US4301807A Apparatus and method for temperature compensated transcutaneous carbon dioxide measurement 失效
标题翻译：用于温度补偿经皮二氧化碳测量的装置和方法
公开(公告)号：US4301807A
公开(公告)日：1981-11-24
申请号：US100501
申请日：1979-12-05
申请人： Richard A. Mentelos
发明人： Richard A. Mentelos
IPC分类号： A61B5/00
CPC分类号： A61B5/14542 , A61B5/1477 , A61B5/1491
摘要： An improved apparatus for non-invasive measurement of transcutaneous carbon dioxide pressure employs a skin engaging sensor including pH and reference electrodes and a temperature sensor. The temperature sensor produces an output signal voltage having a characteristic which can be the same as or the complement of the voltage-temperature characteristic of the deviation voltage component of the pH-reference electrode voltage attributable to temperature deviation effects on the sensor as well as on the skin. An error signal voltage produced at the output of the temperature sensor is combined with the voltage measured across the pH and reference electrodes to provide a corrected voltage having a magnitude indicative of transcutaneous carbon dioxide pressure at a predetermined reference temperature without need to heat the skin or electrode or otherwise control their temperatures.
摘要翻译：用于非侵入性测量经皮二氧化碳压力的改进装置采用皮肤接合传感器，其包括pH和参比电极以及温度传感器。温度传感器产生一个输出信号电压，该输出信号电压可以与由于对传感器的温度偏差影响而引起的pH参考电极电压的偏差电压分量的电压 - 温度特性的相同或互补，皮。在温度传感器的输出处产生的误差信号电压与在pH和参考电极两端测量的电压相结合，以提供具有指示经过预定参考温度的经皮二氧化碳压力的幅度的校正电压，而不需要加热皮肤或电极或以其他方式控制其温度。

5. 发明授权

US4290431A Transcutaneous oxygen and local perfusion measurement 失效
标题翻译：经皮氧气和局部灌注测量
公开(公告)号：US4290431A
公开(公告)日：1981-09-22
申请号：US50691
申请日：1979-06-21
申请人： Normand C. Herbert , Richard S. Burwen , Richard A. Mentelos
发明人： Normand C. Herbert , Richard S. Burwen , Richard A. Mentelos
IPC分类号： A61B5/00 , G01N27/403 , G01N27/49
CPC分类号： A61B5/1491 , G01N27/404
摘要： An apparatus and method for measuring and monitoring blood oxygen content and local perfusion factor. A transcutaneous gas measurement probe is heated by application of an electric current to a semi-conductor device housed therein. The heat developed in a semi-conductor device heats the probe to a constant temperature under the control of a temperature monitoring and regulating circuit and the amount of power applied to the semi-conductor device is measured by multiplying the current conducted through the semiconductor device by the voltage across it to provide a measurement of local perfusion factor. An alerting device is provided to signal when blood oxygen content and local perfusion factor are outside a predetermined acceptable range.
摘要翻译：一种用于测量和监测血氧含量和局部灌注因子的装置和方法。通过向容纳在其中的半导体装置施加电流来加热经皮气体测量探针。在半导体器件中产生的热量在温度监控和调节电路的控制下将探头加热到恒定温度，并且通过将通过半导体器件传导的电流乘以半导体器件所传导的电流来测量施加到半导体器件的功率量其上的电压提供局部灌注因子的测量。提供警报装置以在血氧含量和局部灌注因子超出预定的可接受范围时发出信号。

6. 发明授权

US4023563A Apparatus and method for determining onset times of pulses and use thereof in computing interarterial blood pressure electromechanical interval 失效
标题翻译：用于确定脉冲起始时间的装置和方法及其在计算动脉内血压机电间隔中的用途
公开(公告)号：US4023563A
公开(公告)日：1977-05-17
申请号：US615305
申请日：1975-09-22
申请人： Charles A. Reynolds , Richard A. Mentelos , Donald E. Lewis
发明人： Charles A. Reynolds , Richard A. Mentelos , Donald E. Lewis
IPC分类号： A61B5/02 , A61B5/0285 , G01R29/02 , H03K5/153
CPC分类号： A61B5/0285 , H03K5/153
摘要： Apparatus and a method for determining the onset of an interarterial blood pressure pulse and measuring the time delay preceding the onset from the corresponding electrical heartbeart triggering signal wherein the blood pressure pulse is converted to an electrical input signal which is split into two identical components, one being delayed in time, inverted and amplified after which it is added to the other. A timer measures the duration between the electrical heartbeat actuating signal and the point at which the sum of the blood pressure component signals reaches a peak and subtracts from that result the time delay applied to the one component to yield the electromechanical interval between the electrical heartbeat signal and onset of the blood pressure pulse.
摘要翻译：用于确定动脉内血压脉冲开始并测量从相应的电心跳触发信号开始之前的时间延迟的装置和方法，其中血压脉冲被转换为被分成两个相同组件的电输入信号，一个延迟时间，反转和放大，之后添加到另一个。定时器测量电心跳启动信号与血压分量信号之和达到峰值的点之间的持续时间，并从该结果中减去施加到一个组件的时间延迟以产生电心跳信号之间的机电间隔并开始血压脉冲。

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