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    • 7. 发明申请
    • TRANSMISSION AND COMPRESSION OF GENETIC DATA
    • 遗传资料的传播和压缩
    • US20130304391A1
    • 2013-11-14
    • US13467292
    • 2012-05-09
    • Carlos Henrique CardonhaRobert R. FriedlanderRicardo Guimaraes HerrmannJames R. KraemerJulio Nogima
    • Carlos Henrique CardonhaRobert R. FriedlanderRicardo Guimaraes HerrmannJames R. KraemerJulio Nogima
    • G01N33/48G06F19/00
    • G06F19/22
    • A method, computer product and computer system of transmitting a compressed genome of an organism: a computer at a source reading an uncompressed sequence and a reference genome from a repository; the computer comparing nucleotides of the genetic sequence of the organism to nucleotides from a reference genome, to find differences where nucleotides of the genetic sequence of the organism which are different from the nucleotides of the reference genome; the computer using the differences to create surprisal data, the surprisal data comprising a starting location of the differences within the reference genome, and the nucleotides from the genetic sequence of the organism which are different from the nucleotides of the reference genome; and the computer transmitting, to a destination, a compressed genome comprising: surprisal data and an indication of the reference genome, discarding sequences of nucleotides that are the same in the sequence of the organism and reference genome.
    • 一种传播生物体的压缩基因组的方法,计算机产品和计算机系统:来自读取未压缩序列的源的计算机和来自储存库的参考基因组; 计算机将生物体的遗传序列的核苷酸与来自参考基因组的核苷酸进行比较,以发现与生物体的遗传序列的核苷酸不同于参照基因组的核苷酸的差异; 使用差异的计算机产生惊人的数据,包括参考基因组内的差异的起始位置的惊奇数据以及与参照基因组的核苷酸不同的生物体的遗传序列的核苷酸; 并且所述计算机向目的地传送压缩的基因组,所述基因组包括:惊人的数据和所述参考基因组的指示,丢弃在所述生物体和参考基因组的序列中相同的核苷酸序列。