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    • 1. 发明申请
    • Sugar-Coated Agent
    • 糖衣剂
    • US20080193533A1
    • 2008-08-14
    • US11885971
    • 2006-03-09
    • Junichi KishimotoReiko Tanaka
    • Junichi KishimotoReiko Tanaka
    • A61K9/36B05C5/00
    • A61K9/2886A61J3/005A61K9/2826A61K9/2866A61K9/2893
    • A sugar-coated agent that includes a core, a film layer that mainly includes a film component, the outer surface of the core being coated with the film layer, a sugar coating layer that mainly includes a sugar coating component, the outside of the film layer being coated with the sugar coating layer, and a middle layer that includes a film component and a sugar coating component and is provided between the film layer and the sugar coating layer, wherein within the middle layer, the concentration of the sugar coating component at the interface between the middle layer and the sugar coating layer is higher than the concentration of the sugar coating component at the interface between the middle layer and the film layer.
    • 一种糖衣剂,其包括芯,主要包括膜组分的膜层,芯的外表面涂覆有膜层,主要包括糖衣组分的糖衣层,膜的外部 涂覆有糖衣层的层,以及包含膜组分和糖衣组分的中间层,并且设置在膜层和糖衣层之间,其中在中间层内,糖包衣组分的浓度在 中间层和糖衣层之间的界面高于中间层和膜层之间的界面处的糖衣组分的浓度。
    • 2. 发明授权
    • Electrophotographic element with acrylic anilide polymer layer
    • 电子照相元件与丙烯酰胺聚合物层
    • US5153087A
    • 1992-10-06
    • US507407
    • 1990-04-11
    • Hiroshi TamuraReiko Tanaka
    • Hiroshi TamuraReiko Tanaka
    • G03G5/07G03G5/14G03G5/147
    • G03G5/142G03G5/071
    • An electrophotographic photoconductor comprises least a photoconductive layer and a charge-injection controlling layer, which are overlaid on an electroconductive support in any order, which charge-injection controlling layer comprises a homopolymer or copolymer of a monomer represented by formula (I): ##STR1## wherein R.sup.1 represents hydrogen or a methyl group; R.sup.2 represents hydrogen, an alkyl group having 1 to 4 carbon atoms, a hydroalkyl group having 1 to 4 carbon atoms, an aryl group which may have a substituent, and an aralkyl group which may have a substituent; and R.sup.3, R.sup.4, R.sup.5, R.sup.6 and R.sup.7 each represent hydrogen, an alkyl group having 1 to 4 carbon atoms, an alkoxy group having 1 to 4 carbon atoms, a hydroxyl group, a nitro group, a nitroso group, a cyano group, a carboxyl group, an alkoxycarbonyl group, an acyl group, a sulfonyl group, an amino group which may have a substituent, a halogen or a trifluoromethyl group.
    • 电子照相感光体包括至少一个光电导层和电荷注入控制层,其以任何顺序重叠在导电载体上,该电荷注入控制层包含由式(I)表示的单体的均聚物或共聚物:(I)其中R1表示氢或甲基; R2表示氢,碳原子数1〜4的烷基,碳原子数1〜4的烷基,可具有取代基的芳基,可具有取代基的芳烷基。 R 3,R 4,R 5,R 6和R 7各自表示氢,碳原子数1〜4的烷基,碳原子数1〜4的烷氧基,羟基,硝基,亚硝基,氰基, 羧基,烷氧基羰基,酰基,磺酰基,可以具有取代基的氨基,卤素或三氟甲基。
    • 8. 发明授权
    • Method for detecting and/or determining ATP from microorganism cells in
a sample
    • 用于从样品中的微生物细胞检测和/或测定ATP的方法
    • US5908751A
    • 1999-06-01
    • US845374
    • 1997-04-24
    • Sachiko HigoReiko Tanaka
    • Sachiko HigoReiko Tanaka
    • C12Q1/66C12Q1/68C12Q1/02G01N33/53
    • C12Q1/66Y10S435/968Y10S435/975
    • The present invention provides a method for detecting and/or determining the ATP from microorganism cells in a sample, which comprises the steps of: centrifuging the sample and removing the supernatant, thereby forming a microorganism cell pellet; adding to the microorganism cell pellet a buffer containing a protease-free soluble protein and an ATP hydrolase and incubating the mixture at a pH of 6.0-8.0; extracting ATP from the microorganism cells with an added ATP extraction agent; and detecting and/or determining the ATP released from the microorganism cells by bioluminescence analysis. The present invention also provides a test kit for detecting and/or determining the ATP from microorganism cells, which comprises a reagent containing a buffer capable of pH adjustment to 6.0-8.0, a protease-free soluble protein and an ATP hydrolase, a reagent containing an ATP extraction agent, and a bioluminescence reagent.
    • 本发明提供了一种用于检测和/或测定样品中微生物细胞的ATP的方法,其包括以下步骤:离心样品并除去上清液,从而形成微生物细胞沉淀; 向微生物细胞沉淀中加入含有不含蛋白酶的可溶性蛋白质和ATP水解酶的缓冲液,并在6.0-8.0的pH下孵育该混合物; 用添加的ATP提取剂从微生物细胞中提取ATP; 以及通过生物发光分析检测和/或确定从微生物细胞释放的ATP。 本发明还提供了用于检测和/或测定来自微生物细胞的ATP的测试试剂盒,其包含含有pH调节至6.0-8.0的缓冲液的试剂,不含蛋白酶的可溶性蛋白质和ATP水解酶,含有 ATP提取剂和生物发光试剂。
    • 9. 发明授权
    • Sugar-coated agent
    • 糖衣剂
    • US07927625B2
    • 2011-04-19
    • US11885971
    • 2006-03-09
    • Junichi KishimotoReiko Tanaka
    • Junichi KishimotoReiko Tanaka
    • A61K9/24A61K9/36
    • A61K9/2886A61J3/005A61K9/2826A61K9/2866A61K9/2893
    • A sugar-coated agent that includes a core, a film layer that mainly includes a film component, the outer surface of the core being coated with the film layer, a sugar coating layer that mainly includes a sugar coating component, the outside of the film layer being coated with the sugar coating layer, and a middle layer that includes a film component and a sugar coating component and is provided between the film layer and the sugar coating layer, wherein within the middle layer, the concentration of the sugar coating component at the interface between the middle layer and the sugar coating layer is higher than the concentration of the sugar coating component at the interface between the middle layer and the film layer.
    • 一种糖衣剂,其包括芯,主要包括膜组分的膜层,芯的外表面涂覆有膜层,主要包括糖衣组分的糖衣层,膜的外部 涂覆有糖衣层的层,以及包含膜组分和糖衣组分的中间层,并且设置在膜层和糖衣层之间,其中在中间层内,糖包衣组分的浓度在 中间层和糖衣层之间的界面高于中间层和膜层之间的界面处的糖衣组分的浓度。