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1. 发明授权

US08481331B2 Oxidative dye composition and indicator 有权
标题翻译：氧化染料组成及指示剂
公开(公告)号：US08481331B2
公开(公告)日：2013-07-09
申请号：US11222335
申请日：2005-09-08
申请人： Tricia Cregger , Randal W. Eveland , Antoinette Bower
发明人： Tricia Cregger , Randal W. Eveland , Antoinette Bower
IPC分类号： G01N21/75
CPC分类号： G01N21/78 , C09B21/00 , G01N31/226 , Y10T436/109163
摘要： An oxidative dye indicator composition comprising an indicator dye that has been pre-reacted with a reducing agent prior to use in an oxidizing or disinfectant sterilizing system. The pre-reacted dye, when subjected to an oxidizing disinfection or sterilization agent, such as peracetic acid or hydrogen peroxide, under goes a visible color change and thus can serve as a chemical, process, or chemical integrator, indicator. The dyes include various azines, thiazines, and oxazines compounds and the reducing agents include alkali metal alkoxides and alkaline earth metal alkoxide compounds.
摘要翻译：一种氧化染料指示剂组合物，其包含在用于氧化或消毒灭菌系统之前已经与还原剂预反应的指示剂染料。当经过氧化消毒或灭菌剂如过乙酸或过氧化氢时，预反应的染料发生可见的颜色变化，因此可以用作化学，过程或化学积分器指示剂。染料包括各种吖嗪，噻嗪和恶嗪化合物，还原剂包括碱金属醇盐和碱土金属醇盐化合物。

2. 发明申请

US20090047176A1 INDICATOR FOR MONITORING A STERILIZATION PROCESS 有权
标题翻译：用于监测灭菌过程的指标
公开(公告)号：US20090047176A1
公开(公告)日：2009-02-19
申请号：US11839553
申请日：2007-08-16
申请人： Tricia A. Cregger , Phillip P. Franciskovich , Antoinette Bower , Randal W. Eveland , Michael A. Centanni
发明人： Tricia A. Cregger , Phillip P. Franciskovich , Antoinette Bower , Randal W. Eveland , Michael A. Centanni
IPC分类号： A61L2/18 , A61L2/20 , G01N21/77 , G01N31/22
CPC分类号： A61L2/28
摘要： The disclosed invention relates to an indicator composition comprising at least one iodide salt, at least one binder, at least one carbonate salt and/or at least one sulfate salt, and at least one antioxidant. The indicator composition may contain at least one dye, complexing agent, inhibitor, and/or solvent. A sterilization indicator comprising the foregoing indicator composition is disclosed. The sterilization indicator may be used for monitoring sterilization processes involving oxidative chemistries.
摘要翻译：所公开的发明涉及包含至少一种碘化物盐，至少一种粘合剂，至少一种碳酸盐和/或至少一种硫酸盐和至少一种抗氧化剂的指示剂组合物。指示剂组合物可以含有至少一种染料，络合剂，抑制剂和/或溶剂。公开了包含上述指示剂组合物的灭菌指示剂。灭菌指示剂可用于监测涉及氧化化学物质的灭菌过程。

3. 发明授权

US08512633B2 Indicator for monitoring a sterilization process 有权
标题翻译：监测灭菌过程的指标
公开(公告)号：US08512633B2
公开(公告)日：2013-08-20
申请号：US11839553
申请日：2007-08-16
申请人： Tricia A. Cregger , Phillip P. Franciskovich , Antoinette Bower , Randal W. Eveland , Michael A. Centanni
发明人： Tricia A. Cregger , Phillip P. Franciskovich , Antoinette Bower , Randal W. Eveland , Michael A. Centanni
IPC分类号： A61L9/00
CPC分类号： A61L2/28
摘要： The disclosed invention relates to an indicator composition comprising at least one iodide salt, at least one binder, at least one carbonate salt and/or at least one sulfate salt, and at least one antioxidant. The indicator composition may contain at least one dye, complexing agent, inhibitor, and/or solvent. A sterilization indicator comprising the foregoing indicator composition is disclosed. The sterilization indicator may be used for monitoring sterilization processes involving oxidative chemistries.
摘要翻译：所公开的发明涉及包含至少一种碘化物盐，至少一种粘合剂，至少一种碳酸盐和/或至少一种硫酸盐和至少一种抗氧化剂的指示剂组合物。指示剂组合物可以含有至少一种染料，络合剂，抑制剂和/或溶剂。公开了包含上述指示剂组合物的灭菌指示剂。灭菌指示剂可用于监测涉及氧化化学物质的灭菌过程。

4. 发明授权

US06924139B2 Self-contained biological indicator 有权
标题翻译：独立生物指示剂
公开(公告)号：US06924139B2
公开(公告)日：2005-08-02
申请号：US10620824
申请日：2003-07-16
申请人： Randal W. Eveland , Tricia A. Cregger
发明人： Randal W. Eveland , Tricia A. Cregger
IPC分类号： C12Q1/04 , C12M1/34
CPC分类号： C12Q1/04
摘要： A self-contained biological indicator for evaluating the effectiveness of a sterilizer utilizing an anti-microbial gas or liquid fluid. The indicator is comprised of a tubular casing having open ends and defining an interior chamber. A source of viable microorganisms is disposed within the chamber. A frangible ampoule containing a culture medium capable of promoting growth of the microorganism and a detector means capable of reaction with the metabolites of the microorganism to produce a visual indication is disposed within the chamber. The ampule is operable by pressure applied to an external surface thereof to permit the microorganism and the medium to come into contact with each other. A cap assembly is mounted to each end of the tubular casing. Each cap assembly includes a telescoping element movable from a first position defining an opening communicating with the chamber and a second position crushing the ampoule and forming a gas/fluid impermeable seal around the chamber.
摘要翻译：用于评估使用抗微生物气体或液体流体的灭菌器的有效性的独立生物学指示剂。指示器包括具有开口端并限定内部腔室的管状壳体。活菌的来源设置在室内。包含能够促进微生物生长的培养基的易碎安瓿和能够与微生物的代谢物反应以产生视觉指示的检测器装置设置在室内。安瓿可通过施加到其外表面的压力操作，以允许微生物和介质彼此接触。帽组件安装到管状壳体的每个端部。每个盖组件包括可从限定与腔连通的开口的第一位置移动的伸缩元件和破碎安瓿的第二位置，并且围绕该腔室形成气体/流体不可渗透密封件。

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