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    • 4. 发明申请
    • DETERMINATION OF THE HYDRODYNAMIC RADII AND/OR CONTENT OF CONSTITUENTS OF A MIXTURE BY ANALYSIS OF THE TAYLOR DISPERSION OF THE MIXTURE IN A CAPILLARY TUBE
    • 通过分析毛细管中混合物的水分散度来确定混合物的水动力RADII和/或内容物
    • US20110264380A1
    • 2011-10-27
    • US13055350
    • 2009-03-13
    • Hervé CottetRachid MatmourJean Philippe BironMichel Martin
    • Hervé CottetRachid MatmourJean Philippe BironMichel Martin
    • G06F19/00G01N33/00
    • B01J19/0053B01J2208/00955G01N15/1459G01N33/442G01N2015/0092G01N2030/001
    • A method for analysing a mixture M comprising (i) a first monodisperse species, and (ii) a second species having a response coefficient which is distinct from the response coefficient of the first species (i) on at least one detection device, said method comprising the following steps: (A) the mixture M is injected at the inlet of a capillary tube and forced to be transported in said tube by the flow of a carrier liquid induced by a positive hydrodynamic and/or hydrostatic pressure between the inlet and the outlet of the capillary, whereby a phenomenon of Taylor dispersion of the species of the mixture M occurs in the tube; (B) by using a detection device able to detect simultaneously both species (i) and (ii) and placed in the region of the outlet of the capillary tube, a signal reflecting the Taylor dispersion obtained in step (A) is measured; (C) the signal obtained in step (B) is analysed, so as to determine specific contributions of species (i) and (ii) and thereby establishing at least one of the followings: —the content of species (i) and/or (ii) in the mixture M; and/or, —the mean hydrodynamic radius of the species (ii) or the hydrodynamic radius of species (i).
    • 一种用于分析混合物M的方法,包括(i)第一单分散物质和(ii)具有与至少一种检测装置上的第一物质(i)的响应系数不同的响应系数的第二物质,所述方法 包括以下步骤:(A)混合物M在毛细管的入口处被注入,并且被迫通过由正的流体动力学和/或静水压力引起的载体流在所述管内被输送到入口和 毛细管的出口,由此在管中发生混合物M的种类的泰勒分散现象; (B)通过使用能够同时检测物质(i)和(ii)并且放置在毛细管的出口的区域中的检测装置,测量反映步骤(A)中获得的泰勒色散的信号; (C)分析步骤(B)中获得的信号,以便确定物种(i)和(ii)的具体贡献,从而建立以下至少一个: - 物种(i)和/或 (ii)在混合物M中; 和/或 - 物种(ii)的平均流体动力学半径或物质(i)的流体动力学半径。