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    • 6. 发明申请
    • Transdermal Systems for the Delivery of Ionic Agents Directly to Open Wounds and Surgically Repaired Incisions
    • 透皮系统用于直接输送离子代谢物以开放伤口和手术修复切口
    • US20110112465A1
    • 2011-05-12
    • US13009999
    • 2011-01-20
    • Carter R. AndersonRussell L. MorrisRobert Cohen
    • Carter R. AndersonRussell L. MorrisRobert Cohen
    • A61N1/30
    • A61N1/0448
    • A transdermal system for the delivery of an anesthetic or other active therapeutic agent directly to a selected site of injured skin tissue by iontophoresis is disclosed, which utilizes a transdermal skin-worn patch including a donor electrode chamber containing a donor electrode and an amount of an active agent in a form suitable for transdermal delivery in electrical communication with the donor electrode and a return electrode. The patch also contains a source of electric current connected in a circuit with the donor and return electrode, a current regulating device is optionally provided in the circuit for controlling the electrical output of the patch and at least the donor electrode chamber includes a provision for absorbing a quantity of fluid associated with weepage from adjacent injured skin tissue.
    • 公开了一种用于通过离子电渗法将麻醉剂或其它活性治疗剂直接递送至受损皮肤组织的选定部位的透皮系统,其利用透皮的皮肤佩戴的贴片,其包括供体电极室,其包含施主电极和 活性剂,其形式适合于与供体电极和返回电极电连通的透皮递送。 贴片还包含与供体和返回电极在电路中连接的电流源,电路中可选地提供电流调节装置,用于控制贴片的电输出,并且至少供体电极室包括用于吸收 与来自相邻受伤皮肤组织的渗漏相关的一定量的流体。
    • 8. 发明授权
    • Transdermal systems for the delivery of ionic agents directly to open wounds and surgically repaired incisions
    • 用于将离子剂直接递送至开放性伤口和手术修复的切口的透皮系统
    • US07904146B2
    • 2011-03-08
    • US11937769
    • 2007-11-09
    • Carter R. AndersonRussell L. MorrisRobert Cohen
    • Carter R. AndersonRussell L. MorrisRobert Cohen
    • A61N1/30A61M31/00A61F13/00
    • A61N1/0448
    • A transdermal system for the delivery of an anesthetic or other active therapeutic agent directly to a selected site of injured skin tissue by iontophoresis is disclosed, which utilizes a transdermal skin-worn patch including a donor electrode chamber containing a donor electrode and an amount of an active agent in a form suitable for transdermal delivery in electrical communication with the donor electrode and a return electrode. The patch also contains a source of electric current connected in a circuit with the donor and return electrode, a current regulating device is optionally provided in the circuit for controlling the electrical output of the patch and at least the donor electrode chamber includes a provision for absorbing a quantity of fluid associated with weepage from adjacent injured skin tissue.
    • 公开了一种用于通过离子电渗法将麻醉剂或其它活性治疗剂直接递送至受损皮肤组织的选定部位的透皮系统,其利用透皮的皮肤佩戴的贴片,其包括供体电极室,其包含施主电极和 活性剂,其形式适合于与供体电极和返回电极电连通的透皮递送。 贴片还包含与供体和返回电极在电路中连接的电流源,电路中可选地提供电流调节装置,用于控制贴片的电输出,并且至少供体电极室包括用于吸收 与来自相邻受伤皮肤组织的渗漏相关的一定量的流体。
    • 9. 发明申请
    • Transdermal Systems for the Delivery of Ionic Agents Directly to Open Wounds and Surgically Repaired Incisions
    • 透皮系统用于直接输送离子代谢物以开放伤口和手术修复切口
    • US20080114284A1
    • 2008-05-15
    • US11937769
    • 2007-11-09
    • Carter R. AndersonRussell L. MorrisRobert Cohen
    • Carter R. AndersonRussell L. MorrisRobert Cohen
    • A61N1/30
    • A61N1/0448
    • A transdermal system for the delivery of an anesthetic or other active therapeutic agent directly to a selected site of injured skin tissue by iontophoresis is disclosed, which utilizes a transdermal skin-worn patch including a donor electrode chamber containing a donor electrode and an amount of an active agent in a form suitable for transdermal delivery in electrical communication with the donor electrode and a return electrode. The patch also contains a source of electric current connected in a circuit with the donor and return electrode, a current regulating device is optionally provided in the circuit for controlling the electrical output of the patch and at least the donor electrode chamber includes a provision for absorbing a quantity of fluid associated with weepage from adjacent injured skin tissue.
    • 公开了一种用于通过离子电渗法将麻醉剂或其它活性治疗剂直接递送至受损皮肤组织的选定部位的透皮系统,其利用透皮的皮肤佩戴的贴片,其包括供体电极室,其包含施主电极和 活性剂,其形式适合于与供体电极和返回电极电连通的透皮递送。 贴片还包含与供体和返回电极在电路中连接的电流源,电路中可选地提供电流调节装置,用于控制贴片的电输出,并且至少供体电极室包括用于吸收 与来自相邻受伤皮肤组织的渗漏相关的一定量的流体。