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1. 发明申请

US20080069843A1 Salmonella vaccine 审中-公开
标题翻译：沙门氏菌疫苗
公开(公告)号：US20080069843A1
公开(公告)日：2008-03-20
申请号：US11980864
申请日：2007-10-30
申请人： Petrus Nuijten , Maarten Witvliet
发明人： Petrus Nuijten , Maarten Witvliet
IPC分类号： A61K39/112
CPC分类号： A61K39/0275 , A61K2039/521 , A61K2039/522 , A61K2039/523 , Y02A50/482
摘要： The present invention relates to Salmonella bacteria. The invention also relates to methods of using Salmonella bacteria, including in vaccines based thereon that are useful for the prevention of microbial pathogenesis. Further, the invention relates to the use of such bacteria or the manufacture of such vaccines. The invention also relates to methods for the preparation of such vaccines.
摘要翻译：本发明涉及沙门氏菌。本发明还涉及使用沙门菌细菌的方法，包括在其上用于预防微生物发病机理的疫苗中。此外，本发明涉及这种细菌的使用或这种疫苗的制造。本发明还涉及制备这种疫苗的方法。

2. 发明申请

US20080008718A1 Ornithobacterium Rhinotracheale Subunit Vaccines 审中-公开
标题翻译：燕麦Rhinotracheale亚基疫苗
公开(公告)号：US20080008718A1
公开(公告)日：2008-01-10
申请号：US10588992
申请日：2005-02-09
申请人： Danielle Schuijffel , Petrus Nuijten
发明人： Danielle Schuijffel , Petrus Nuijten
IPC分类号： A61K39/40 , A61K39/02 , A61K39/102 , A61K39/112 , A61K39/12 , A61P31/04 , C07H21/00 , C12N1/00 , C07K14/195 , A61P31/12 , A61P31/00 , A61K39/17 , A61K39/255 , A61K39/265
CPC分类号： C07K14/195 , A61K39/00
摘要： The present invention relates to nucleic acids encoding Ornithobacterium rhinotracheale proteins, to DNA fragments, recombinant DNA molecules, live recombinant carriers and host cells comprising such nucleic acids, to Ornithobacterium rhinotracheale proteins, to antibodies against such proteins, to such proteins for use in vaccines, to the use of such proteins in the manufacturing of such vaccines, to vaccines comprising such nucleic acids, DNA fragments, recombinant DNA molecules, live recombinant carriers, host cells, proteins or antibodies against such proteins, and to methods for the preparation of such vaccines.
摘要翻译：本发明涉及编码鸟氨酸鼻杆菌蛋白质的核酸，DNA片段，重组DNA分子，活重组载体和包含这种核酸的宿主细胞，鼻咽鼻气管炎蛋白质，抗这种蛋白质的抗体，用于疫苗中使用的蛋白质，关于在制造这种疫苗中使用这样的蛋白质，涉及包含这种核酸的疫苗，DNA片段，重组DNA分子，活重组载体，宿主细胞，针对这种蛋白质的蛋白质或抗体，以及用于制备这种疫苗的方法。

3. 发明授权

US06489839B2 Amplifier with output transformer 失效
标题翻译：带输出变压器的放大器
公开(公告)号：US06489839B2
公开(公告)日：2002-12-03
申请号：US09888460
申请日：2001-06-25
申请人： Rob Maaskant , Cornelis Petrus Nuijten
发明人： Rob Maaskant , Cornelis Petrus Nuijten
IPC分类号： H03F338
CPC分类号： H03F3/26 , H03F3/217
摘要： An amplifier for use in, for example, Public Address Systems to send audio signals over long distances, is of the push-pull type and includes a first and a second switch and an output transformer having a primary winding coupled to the switches and a secondary winding coupled to the output of the push-pull amplifier. The output transformer further includes a further secondary winding coupled to a comparator as a feedback loop.
摘要翻译：用于例如公共广播系统中用于长距离发送音频信号的放大器是推挽型的，并且包括第一和第二开关以及具有耦合到开关的初级绕组的输出变压器和次级绕组耦合到推挽放大器的输出。输出变压器还包括作为反馈回路耦合到比较器的另外的次级绕组。

4. 发明申请

US20050255125A1 Streptococcus uberis protein, nucleic acid sequence encoding the same and its use in a mastitis vaccine 失效
标题翻译：乳房链球菌蛋白，编码相同的核酸序列及其在乳腺炎疫苗中的应用
公开(公告)号：US20050255125A1
公开(公告)日：2005-11-17
申请号：US10524198
申请日：2003-08-06
申请人： Petrus Nuijten , Selma Hensen
发明人： Petrus Nuijten , Selma Hensen
IPC分类号： G01N33/53 , A61K35/74 , A61K35/76 , A61K39/00 , A61K39/09 , A61K48/00 , A61P31/04 , C07K14/315 , C07K16/12 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/31 , C12N15/63 , C12Q1/68 , C07H21/04 , A61K39/02 , C12N15/74
CPC分类号： C07K14/315 , A61K39/00
摘要： The present invention relates to nucleic acid sequences encoding a 22.5 kD Streptococcus uberis protein and to parts of such nucleic acid sequences that encode an immunogenic fragment of such proteins, and to DNA fragments, recombinant DNA molecules, live recombinant carriers and host cells comprising such nucleic acid sequences or such parts thereof. The invention also relates to a 22.5 kD Streptococcus uberis protein and immunogenic parts thereof encoded by such sequences. Furthermore, the present invention relates to vaccines comprising such nucleic acid sequences and parts thereof, DNA fragments, recombinant DNA molecules, live recombinant carriers and host cells comprising such nucleic acid sequences or such parts thereof, proteins or immunogenic parts thereof and antibodies against such proteins or immunogenic parts thereof. Also, the invention relates to the use of said proteins in vaccines and for the manufacture of vaccines. Moreover, the invention relates to the use of said nucleic acid sequences, proteins or antibodies for diagnostic or vaccination purposes. Finally the invention relates to diagnostic kits comprising such a nucleic acid, protein or antibodies against such protein.
摘要翻译：本发明涉及编码22.5kD乳房链球菌蛋白质的核酸序列和编码这种蛋白质的免疫原性片段的这些核酸序列的部分，以及DNA片段，重组DNA分子，活重组载体和包含该核酸的宿主细胞酸序列或其部分。本发明还涉及由这样的序列编码的22.5kD乳房链球菌蛋白及其免疫原性部分。此外，本发明涉及包含此类核酸序列及其部分的DNA疫苗，DNA片段，重组DNA分子，活重组载体和包含此类核酸序列或其部分的宿主细胞，蛋白质或其免疫原性部分和针对此类蛋白质的抗体或其免疫原性部分。此外，本发明涉及所述蛋白质在疫苗中的用途以及制造疫苗。此外，本发明涉及用于诊断或疫苗接种目的的所述核酸序列，蛋白质或抗体的用途。最后，本发明涉及包含这种核酸，蛋白质或抗这种蛋白质的抗体的诊断试剂盒。

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