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1. 发明申请

US20060293258A1 Method and composition to treat skin ulcers 审中-公开
标题翻译：治疗皮肤溃疡的方法和组成
公开(公告)号：US20060293258A1
公开(公告)日：2006-12-28
申请号：US11166510
申请日：2005-06-23
申请人： Peter Rohdewald
发明人： Peter Rohdewald
IPC分类号： A61K31/7048 , A61K31/353 , A61K9/48
CPC分类号： A61K9/0014 , A61K31/353 , A61K31/7048 , A61K36/15
摘要： The invention is directed to a method for treating ulcers, including ulcers of the lower leg, by topical plus oral administration of proanthocyanidins to a patient.
摘要翻译：本发明涉及通过局部加口服给予原花色素的方法来治疗溃疡，包括小腿溃疡。

2. 发明申请

US20060194746A1 Method and composition to inhibit infections with Helicobacter pylori by intake of procyanidins from type B and C 审中-公开
标题翻译：通过从B型和C型摄入原花青素抑制幽门螺杆菌感染的方法和组合物
公开(公告)号：US20060194746A1
公开(公告)日：2006-08-31
申请号：US11069523
申请日：2005-02-28
申请人： Peter Rohdewald
发明人： Peter Rohdewald
IPC分类号： A61K31/7048 , A61K31/353
CPC分类号： A61K31/353
摘要： Methods and compositions, including, foods and beverages, for treating, preventing or ameliorating Helicobacter pylori-associated disorders, particularly disorders of the gastrointestinal tract such as peptic ulcers of the stomach are provided by this disclosure. In one preferred aspect, the method comprises administering to a Helicobacter pylori infected subject a therapeutically effective amount of a composition comprising Type-B procyanidins, Type-C procyanidins, or a mixture thereof.
摘要翻译：通过本公开提供了用于治疗，预防或改善幽门螺杆菌相关疾病，特别是胃肠道疾病如胃消化性溃疡的方法和组合物，包括食品和饮料。在一个优选的方面，所述方法包括向幽门螺杆菌感染受试者施用治疗有效量的包含B型原花青素，C型原花青素或其混合物的组合物。

3. 发明授权

US5720956A Method of controlling the reactivity of human blood platelets by oral administration of the extract of the maritime pine (pycnogenol) 失效
标题翻译：通过口服海绵松提取物来控制人血小板反应性的方法
公开(公告)号：US5720956A
公开(公告)日：1998-02-24
申请号：US631738
申请日：1996-04-10
申请人： Peter Rohdewald
发明人： Peter Rohdewald
IPC分类号： A61K36/00 , A61K36/15 , A61K36/18 , A61P7/02 , A61P9/08 , A61P9/10 , A61K35/78
CPC分类号： A61K36/15 , Y10S514/822
摘要： A method of inhibiting platelet aggregation with an agent which is able to normalize and enhance platelet reactivity without adversely affecting the bleeding time. The method additionally prevents adrenaline-induced platelet aggregation.
摘要翻译：用能够使血小板反应性正常化并且不会不利地影响出血时间的药剂来抑制血小板聚集的方法。该方法另外防止肾上腺素诱导的血小板聚集。

4. 发明申请

US20070059392A1 COX inhibitor 审中-公开
标题翻译： COX抑制剂
公开(公告)号：US20070059392A1
公开(公告)日：2007-03-15
申请号：US11300119
申请日：2005-12-13
申请人： Peter Rohdewald
发明人： Peter Rohdewald
IPC分类号： A61K36/13 , A61K31/7048 , A61K31/353
CPC分类号： A61K36/15 , A61K31/353 , A61K31/7048
摘要： Methods and compositions for inhibition of both COX-1 and COX-2 are provided by this disclosure. The methods and compositions on the invention are effective for providing relief from pain.
摘要翻译：本公开提供了抑制COX-1和COX-2的方法和组合物。本发明的方法和组合物对于缓解疼痛是有效的。

5. 发明申请

US20050171030A1 Relieving symptoms of erectile dysfunction and attaining sexual wellness and health of the sexual vascular system with proanthocyanidins 审中-公开
标题翻译：缓解勃起功能障碍的症状，并通过原花色素达到性维生素和性维生素健康
公开(公告)号：US20050171030A1
公开(公告)日：2005-08-04
申请号：US11054742
申请日：2005-02-09
申请人： Peter Rohdewald , Victor Ferrari
发明人： Peter Rohdewald , Victor Ferrari
IPC分类号： A61K31/195 , A61K31/198 , A61K31/353 , A61K31/4745 , A61K31/519 , A61K31/7048 , A61K33/00 , A61K36/00 , A61K36/185 , A61K36/74 , A61K45/06 , A61K35/78
CPC分类号： A61K45/06 , A61K31/195 , A61K31/198 , A61K31/7048 , A61K33/00 , A61K36/185 , A61K36/74 , A61K2300/00
摘要： Sexual wellness or sexual fitness is enhanced over time by administrating on a daily basis a source of proanthocyanidins and a source of arginine. Both sources may be blended into a composition or taken separately from a kit. The source of arginine may be a salt or peptide of L-arginine and aspartic acid such as arginine aspartate. The proanthocyanidins stimulate an endothelial NO-synthase enzyme, which serves as a catalyst for synthesis of the nitric oxide from a substration that is the source of the arginine. A sufficient amount of the nitric oxide is released over time to enhance sexual wellness or sexual fitness. In case of low levels of androgenic hormones in both sexes, the combination may contain as a further ingredient a sex hormone or a sex hormone precursor or a sex hormone stimulant or a sex hormone bioavailability enhancer.
摘要翻译：随着时间的推移，性健康或性健康日益加强，原花青素源和精氨酸来源。两种来源可以混合成组合物或者与试剂盒分离。精氨酸的来源可以是L-精氨酸和天冬氨酸的盐或肽，例如天冬氨酸精氨酸。原花色素刺激内皮NO合成酶，其作为从作为精氨酸来源的子区合成一氧化氮的催化剂。随着时间的推移释放足量的一氧化氮以增强性健康或性健康。在男女雄激素激素水平低的情况下，该组合可以含有性激素或性激素前体或性激素兴奋剂或性激素生物利用度增强剂作为其他成分。

6. 发明授权

US06565851B2 Relieving symptoms of erectile dysfunction with proanthocyanidins 有权
标题翻译：缓解原花青素勃起功能障碍症状
公开(公告)号：US06565851B2
公开(公告)日：2003-05-20
申请号：US09865189
申请日：2001-05-24
申请人： Peter Rohdewald , Victor Ferrari
发明人： Peter Rohdewald , Victor Ferrari
IPC分类号： A61K39385
CPC分类号： A61K36/15 , A61K2300/00
摘要： Use of proanthocyanidins as an active ingredient of a stimulator as a source of arginine and a source of nitric oxide in the treatment of erectile dysfunction. The active ingredient stimulates the endothelial NO-synthase enzyme, which acts as a catalyst for the synthesis of nitric oxide from its substrate L-arginine or its salts. The nitric oxide in turn activates theguanylyl cyclase, which leads to an increased development of cyclic guanosine monophosphate, which causes relaxation of smooth muscles. Blood vessel diameter may increase. The stimulator may also have Sildenafil or enzymes that inhibit an enzyme phosphodiesterase type5 from reducing an amount of the cyclic guanosine monophosphate. The substrate may be amino acid L-arginine, arginine salts or a dipeptide of arginine and aspartic acid.
摘要翻译：使用原花青素作为刺激剂的活性成分，作为精氨酸的来源和一氧化氮来治疗勃起功能障碍。活性成分刺激内皮NO合成酶，其作为从其底物L-精氨酸或其盐合成一氧化氮的催化剂。一氧化氮依次激活胍基环化酶，导致环鸟苷酸单磷酸酯的增加，导致平滑肌松弛。血管直径可能增加。刺激剂还可以具有抑制酶5磷酸二酯酶的西地那非或酶，从而减少环鸟苷酸一磷酸的量。底物可以是氨基酸L-精氨酸，精氨酸盐或精氨酸和天冬氨酸的二肽。

7. 发明申请

US20070269541A1 Method and compositions for relieving menopausal and perimenopausal symptoms 审中-公开
标题翻译：减轻绝经期和绝经期症状的方法和组合物
公开(公告)号：US20070269541A1
公开(公告)日：2007-11-22
申请号：US11437334
申请日：2006-05-19
申请人： Peter Rohdewald
发明人： Peter Rohdewald
IPC分类号： A61K36/87 , A61K36/13 , A61K31/7048 , A61K31/353
CPC分类号： A61K36/15 , A61K31/353 , A61K31/7048 , A61K36/87
摘要： The present invention is directed to novel methods of treating and reducing perimenopausal and climacteric symptoms using compositions comprising proanthocyanidins. In one embodiment, the methods provide for perimenopausal and climacteric symptom reduction without the use of female hormones or hormone like substances.
摘要翻译：本发明涉及使用包含原花青素的组合物治疗和减少围绝经期和更年期症状的新方法。在一个实施方案中，所述方法提供围绝经期和更年期症状减轻，而不使用雌激素或激素样物质。

8. 发明申请

US20050155615A1 Air filter with scavenging effect on free radicals in gaseous phase and its method of preparation 审中-公开
标题翻译：空气过滤器对气相中的自由基具有清除作用及其制备方法
公开(公告)号：US20050155615A1
公开(公告)日：2005-07-21
申请号：US11019907
申请日：2004-12-21
申请人： Peter Rohdewald , Victor Ferrari
发明人： Peter Rohdewald , Victor Ferrari
IPC分类号： A24D1/04 , A24D3/02 , A24D3/14 , B01D46/00
CPC分类号： A24D3/14
摘要： This invention relates to air filter components and apparatuses that act to scavenge gas phase free radicals present in polluted air. In specific aspects, the invention relates to filters that contain proanthocyanidins for scavenging the free radicals. The present invention is also directed to a method for producing air filter components and apparatuses with scavenging effects on gas phase free radicals.
摘要翻译：本发明涉及用于清除存在于污染空气中的气相自由基的空气过滤器部件和装置。在具体方面，本发明涉及含有用于清除自由基的原花青素的过滤器。本发明还涉及一种用于制造对气相自由基具有清除作用的空气过滤器部件和装置的方法。

9. 发明授权

US06832612B2 Cigarette filter with scavenging effect on free radicals in cigarette smoke and its preparation method 失效
标题翻译：香烟过滤器对香烟烟雾中自由基的清除作用及其制备方法
公开(公告)号：US06832612B2
公开(公告)日：2004-12-21
申请号：US09963041
申请日：2001-09-25
申请人： Baolu Zhao , Peter Rohdewald , Jingnong (Charles) Li
发明人： Baolu Zhao , Peter Rohdewald , Jingnong (Charles) Li
IPC分类号： A24B1518
CPC分类号： A24D3/14
摘要： A cigarette filter that has a scavenging effect on smoking induced gas phase free radicals. The filter ingredients are comprised of proanthocyanidins and include, but are not limited to, extracts of barks of pine tree, extracts of cones of cypress trees, extracts of grape seeds, and any combination thereof. Also, vitamin C and other known antioxidant ingredients may be added.
摘要翻译：一种对吸烟引起的气相自由基具有清除作用的香烟过滤嘴。过滤成分由原花色素组成，包括但不限于松树皮，桧树提取物，葡萄籽提取物及其任何组合的提取物。此外，可以加入维生素C和其他已知的抗氧化成分。

10. 发明申请

US20070014883A1 Method for treating osteoarthritis 审中-公开
标题翻译：治疗骨关节炎的方法
公开(公告)号：US20070014883A1
公开(公告)日：2007-01-18
申请号：US11181198
申请日：2005-07-13
申请人： Peter Rohdewald
发明人： Peter Rohdewald
IPC分类号： A61K31/7048 , A61K31/353 , A61K36/13
CPC分类号： A61K31/7048
摘要： The invention relates to methods for treating osteoarthritis by administering a composition consisting essentially of proanthocyanidins to a patient suffering from such a disorder.
摘要翻译：本发明涉及通过向患有这种病症的患者施用基本上由原花青素组成的组合物来治疗骨关节炎的方法。

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