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1. 发明授权

US08677602B2 Method of making a flexible device shaft with angled spiral wrap 有权
标题翻译：制造具有成角螺旋形包装的柔性装置轴的方法
公开(公告)号：US08677602B2
公开(公告)日：2014-03-25
申请号：US13357676
申请日：2012-01-25
申请人： Peter L. Dayton , Michael P. Boutillette
发明人： Peter L. Dayton , Michael P. Boutillette
IPC分类号： B23P13/00 , H01B7/17
CPC分类号： A61M25/0043 , A61B1/00071 , A61B1/0055 , A61M25/0013 , Y10T29/49995
摘要： Spiral-wound materials, spirals, and shafts made therefrom that have wraps with edges that may nest within one another are described. Such edges allow the spiral to achieve a smaller bending radius, meaning tighter turns and more flexibility due to the ability of adjacent wraps to nest within each other when the shaft is bent. Spirals having wraps with edges capable of nesting can be used in the medical field for devices that track anatomy, such as endoscopes, colonoscopes, catheters, and the like.
摘要翻译：描述了螺旋缠绕材料，螺旋形和由其制成的轴，它们可以彼此嵌套的边缘包裹。这样的边缘允许螺旋获得较小的弯曲半径，这意味着由于当轴弯曲时相邻的缠绕层彼此嵌套的能力，意味着更紧的匝数和更大的柔性。具有能够嵌套的边缘的螺旋可以用于医疗领域用于追踪解剖结构的装置，例如内窥镜，结肠镜，导管等。

2. 发明授权

US07579550B2 Flexible device shaft with angled spiral wrap 有权
标题翻译：柔性装置轴带有螺旋形卷曲
公开(公告)号：US07579550B2
公开(公告)日：2009-08-25
申请号：US11396248
申请日：2006-03-31
申请人： Peter L Dayton , Michael P Boutillette
发明人： Peter L Dayton , Michael P Boutillette
IPC分类号： H01B7/17
CPC分类号： A61M25/0043 , A61B1/00071 , A61B1/0055 , A61M25/0013 , Y10T29/49995
摘要： Spiral-wound materials, spirals, and shafts made therefrom that have wraps with edges that may nest within one another are described. Such edges allow the spiral to achieve a smaller bending radius, meaning tighter turns and more flexibility due to the ability of adjacent wraps to nest within each other when the shaft is bent. Spirals having wraps with edges capable of nesting can be used in the medical field for devices that track anatomy, such as endoscopes, colonoscopes, catheters, and the like.
摘要翻译：描述了螺旋缠绕材料，螺旋形和由其制成的轴，它们可以彼此嵌套的边缘包裹。这样的边缘允许螺旋获得较小的弯曲半径，这意味着由于当轴弯曲时相邻的缠绕层彼此嵌套的能力，意味着更紧的匝数和更大的柔性。具有能够嵌套的边缘的螺旋可以用于医疗领域用于追踪解剖结构的装置，例如内窥镜，结肠镜，导管等。

3. 发明授权

US09272128B2 Methods and systems for attaching medical device sections 有权
标题翻译：用于连接医疗器械部分的方法和系统
公开(公告)号：US09272128B2
公开(公告)日：2016-03-01
申请号：US13754560
申请日：2013-01-30
申请人： Dane T. Seddon , Sean P. Fleury , Mark D. Wood , Peter L. Dayton , Gary S. Kappel , Norman C. May
发明人： Dane T. Seddon , Sean P. Fleury , Mark D. Wood , Peter L. Dayton , Gary S. Kappel , Norman C. May
IPC分类号： A61B17/00 , A61M39/12 , A61M25/00 , A61B1/00 , A61B1/005 , A61B17/29
CPC分类号： A61B1/00071 , A61B1/00128 , A61B1/0055 , A61B17/29 , A61B2017/00314 , A61B2017/00323 , A61B2017/0034 , A61B2017/00464 , A61B2017/00473 , A61B2017/00477 , A61B2017/2905 , A61M25/0043 , A61M39/12
摘要： Embodiments of the disclosure include methods and systems for attaching an articulation section. In an embodiment, a medical instrument includes a first tubular member including a first end. The medical instrument also includes a second tubular member including a first end. The second tubular member includes a plurality of layers including an inner layer and a first layer including a fluorinated material. The inner layer includes a first section disposed under the first layer and a second section extending out from under the first layer. A portion of the first tubular member overlaps and is bonded to at least a portion of the second section of the inner layer of the second tubular member.
摘要翻译：本公开的实施例包括用于附接关节部分的方法和系统。在一个实施例中，医疗器械包括包括第一端的第一管状构件。医疗器械还包括包括第一端的第二管状构件。第二管状构件包括多个层，包括内层和包含氟化材料的第一层。内层包括设置在第一层下方的第一部分和从第一层下方延伸的第二部分。第一管状部件的一部分与第二管状部件的内层的第二部分的至少一部分重叠并结合。

4. 发明授权

US09034346B2 Implantable or insertable medical device resistant to microbial growth and biofilm formation 有权
标题翻译：可植入或可插入的医疗器械抗微生物生长和生物膜形成
公开(公告)号：US09034346B2
公开(公告)日：2015-05-19
申请号：US13357033
申请日：2012-01-24
申请人： Kathleen M. Miller , Gregory T. Sydney , Kurt Geitz , Peter L. Dayton , Ronald A. Sahatjian
发明人： Kathleen M. Miller , Gregory T. Sydney , Kurt Geitz , Peter L. Dayton , Ronald A. Sahatjian
IPC分类号： A61L2/232 , A61L29/16 , A61L31/16
CPC分类号： A61L2/232 , A61L29/16 , A61L31/16 , A61L2300/202 , A61L2300/206 , A61L2300/21 , A61L2300/404 , A61L2300/45 , Y10T428/1334 , Y10T428/1352 , Y10T428/1372 , Y10T428/1379 , Y10T428/1386 , Y10T428/1393
摘要： Disclosed are implantable or insertable medical devices that provide resistance to microbial growth on and in the environment of the device and resistance to microbial adhesion and biofilm formation on the device. In particular, the invention discloses implantable or insertable medical devices that comprise at least one biocompatible matrix polymer region, an antimicrobial agent for providing resistance to microbial growth and a microbial adhesion/biofilm synthesis inhibitor for inhibiting the attachment of microbes and the synthesis and accumulation of biofilm on the surface of the medical device. Also disclosed are methods of manufacturing such devices under conditions that substantially prevent preferential partitioning of any of said bioactive agents to a surface of the biocompatible matrix polymer and substantially prevent chemical modification of said bioactive agents.
摘要翻译：公开了可植入或可插入的医疗装置，其在装置的环境和环境中提供对微生物生长的抵抗力，并且抵抗微生物附着和在装置上的生物膜形成。特别地，本发明公开了可植入或可插入的医疗装置，其包括至少一个生物相容性基质聚合物区域，用于提供对微生物生长的抗性的抗微生物剂和用于抑制微生物附着的微生物粘附/生物膜合成抑制剂以及合成和积累生物膜在医疗器械的表面上。还公开了在基本上防止任何所述生物活性剂优先分配到生物相容性基质聚合物的表面并基本上防止所述生物活性剂的化学修饰的条件下制造这种装置的方法。

5. 发明申请

US20110105847A1 ENDOSCOPE INCLUDING A VARIABLE STATE OPTICAL MEMBER 审中-公开
标题翻译：内窥镜包括一个可变状态的光学成员
公开(公告)号：US20110105847A1
公开(公告)日：2011-05-05
申请号：US12917768
申请日：2010-11-02
申请人： Peter L. Dayton
发明人： Peter L. Dayton
IPC分类号： A61B1/002
CPC分类号： A61B1/04 , A61B1/00177 , A61B1/00183 , A61B1/0019
摘要： In one embodiment, an apparatus may include an elongate member having a proximal end portion and a distal end portion. A variable state optical member may be coupled within the distal end portion of the elongate member. The variable state optical member may include a first configuration and a second configuration different from the first configuration. An imager may be disposed within the distal end portion of the elongate member. The imager may be configured to produce an imaging signal associated with a tissue distal to the elongate member when the variable state optical member is in the first configuration. The imager may be also configured to produce an imaging signal associated with a tissue lateral to the elongate member when the variable state optical member is in the second configuration.
摘要翻译：在一个实施例中，装置可以包括具有近端部分和远端部分的细长构件。可变状态光学构件可以联接在细长构件的远端部分内。可变状态光学构件可以包括与第一构造不同的第一构造和第二构造。成像器可以设置在细长构件的远端部分内。成像器可以被配置为当可变状态光学构件处于第一配置时，产生与细长构件远侧的组织相关联的成像信号。成像器还可以被配置为当可变状态光学构件处于第二配置时，产生与细长构件侧向的组织相关联的成像信号。

6. 发明授权

US07931932B2 Processes for producing polymer coatings through surface polymerization 失效
标题翻译：通过表面聚合生产聚合物涂层的方法
公开(公告)号：US07931932B2
公开(公告)日：2011-04-26
申请号：US12070275
申请日：2008-02-14
申请人： Robert A. Herrmann , Frederick H. Strickler , Wendy Naimark , Peter L. Dayton
发明人： Robert A. Herrmann , Frederick H. Strickler , Wendy Naimark , Peter L. Dayton
IPC分类号： B05D3/06 , C08F2/46 , C08F295/00 , A61F2/06
CPC分类号： A61L31/10 , A61L31/16 , A61L2300/606
摘要： A medical device with a therapeutic agent-releasing polymer coating. The medical device is provided by a method that comprises: (a) attaching at least one reactive species to a medical device surface, which reactive species leads to chain growth polymerization in the presence of monomer; (b) contacting the reactive species with at least one monomer species, thereby forming a polymer coating on the surface of the medical device; and (c) providing at least one therapeutic agent within the polymer coating. The therapeutic agent may be incorporated during formation of the polymer coating or after formation of the polymer coating. The at least one reactive species can comprise, for example, a free radical species, a carbanion species, a carbocation species, a Ziegler-Natta polymerization complex, a metallocene complex, and/or an atom transfer radical polymerization initiator. Alternatively, the medical device is provided by a process comprising: (a) immobilizing least one polymerization catalyst at a medical device surface, which polymerization catalyst leads to polymerization in the presence of monomer; (b) contacting the medical device surface with at least one monomer species, thereby forming a polymer coating at the surface of the medical device; and (c) providing at least one therapeutic agent within the polymer coating.
摘要翻译：具有治疗剂释放聚合物涂层的医疗装置。该医疗装置由一种方法提供，该方法包括：（a）将至少一种反应性物质附着到医疗器械表面上，该反应性物质在单体存在下导致链增长聚合; （b）使反应性物质与至少一种单体物质接触，从而在医疗装置的表面上形成聚合物涂层; 和（c）在聚合物涂层内提供至少一种治疗剂。治疗剂可以在形成聚合物涂层期间或在形成聚合物涂层之后引入。至少一种反应性物质可以包括例如自由基物质，碳负离子物质，碳阳离子物质，齐格勒 - 纳塔聚合配合物，茂金属络合物和/或原子转移自由基聚合引发剂。或者，医疗装置由包括以下步骤的方法提供：（a）在医疗器械表面固定最少一种聚合催化剂，该聚合催化剂在单体存在下导致聚合; （b）使医疗器械表面与至少一种单体物质接触，从而在医疗装置的表面形成聚合物涂层; 和（c）在聚合物涂层内提供至少一种治疗剂。

7. 发明申请

US20130023858A1 FLEXIBLE DEVICE SHAFT WITH ANGLED SPIRAL WRAP 有权
公开(公告)号：US20130023858A1
公开(公告)日：2013-01-24
申请号：US13357676
申请日：2012-01-25
申请人： Peter L. Dayton , Michael P. Boutillette
发明人： Peter L. Dayton , Michael P. Boutillette
IPC分类号： A61B19/02
CPC分类号： A61M25/0043 , A61B1/00071 , A61B1/0055 , A61M25/0013 , Y10T29/49995
摘要： Spiral-wound materials, spirals, and shafts made therefrom that have wraps with edges that may nest within one another are described. Such edges allow the spiral to achieve a smaller bending radius, meaning tighter turns and more flexibility due to the ability of adjacent wraps to nest within each other when the shaft is bent. Spirals having wraps with edges capable of nesting can be used in the medical field for devices that track anatomy, such as endoscopes, colonoscopes, catheters, and the like.

8. 发明授权

US08197400B2 Selectively rotatable shaft coupler 有权
标题翻译：可选择旋转轴联轴器
公开(公告)号：US08197400B2
公开(公告)日：2012-06-12
申请号：US11238153
申请日：2005-09-28
申请人： Michael P. Boutillette , Peter L. Dayton , Dennis R. Boulais
发明人： Michael P. Boutillette , Peter L. Dayton , Dennis R. Boulais
IPC分类号： A61B1/00 , F16L27/00
CPC分类号： A61B1/00128 , A61B1/00124 , Y10T403/32213 , Y10T403/32975 , Y10T403/32983
摘要： The present invention is a system for dissipating loops in an elongated medical device having one end secured to an anchor point, such as a housing. The system includes a selectively rotatable shaft coupler that connects a shaft to the anchor point that allows a limited amount of shaft rotation during use, but which sets a restriction on the maximum amount of shaft rotation. In another embodiment, the invention provides a shaft coupling system for connecting a proximal end of an endoscope shaft to an object without the use of adhesives or fasteners. In another embodiment, the invention provides a rotatable shaft coupling system for rotatably coupling a first and second shaft segment.
摘要翻译：本发明是一种用于在细长的医疗装置中消散环的系统，其具有固定到诸如壳体的锚定点的一端。该系统包括可选择地旋转的轴联接器，其将轴连接到锚定点，其在使用期间允许有限量的轴旋转，但是这限制了轴旋转的最大量。在另一个实施例中，本发明提供一种用于将内窥镜轴的近端连接到物体而不使用粘合剂或紧固件的轴联接系统。在另一个实施例中，本发明提供一种用于可旋转地联接第一和第二轴段的可旋转的轴联接系统。

9. 发明申请

US20120128793A1 IMPLANTABLE OR INSERTABLE MEDICAL DEVICE RESISTANT TO MICROBIAL GROWTH AND BIOFILM FORMATION 有权
公开(公告)号：US20120128793A1
公开(公告)日：2012-05-24
申请号：US13357017
申请日：2012-01-24
申请人： Kathleen M. Miller , Gregory T. Sydney , Kurt Geitz , Peter L. Dayton , Ronald A. Sahatjian
发明人： Kathleen M. Miller , Gregory T. Sydney , Kurt Geitz , Peter L. Dayton , Ronald A. Sahatjian
IPC分类号： A01N31/14 , A01N37/40 , A61K33/24 , A61K31/519 , A61L29/16 , A61K31/337 , A61K31/573 , A01P1/00 , A61P35/00 , A61P29/00 , A01N37/52 , A61K31/704
CPC分类号： A61L2/232 , A61L29/16 , A61L31/16 , A61L2300/202 , A61L2300/206 , A61L2300/21 , A61L2300/404 , A61L2300/45 , Y10T428/1334 , Y10T428/1352 , Y10T428/1372 , Y10T428/1379 , Y10T428/1386 , Y10T428/1393
摘要： Disclosed are implantable or insertable medical devices that provide resistance to microbial growth on and in the environment of the device and resistance to microbial adhesion and biofilm formation on the device. In particular, the invention discloses implantable or insertable medical devices that comprise at least one biocompatible matrix polymer region, an antimicrobial agent for providing resistance to microbial growth and a microbial adhesion/biofilm synthesis inhibitor for inhibiting the attachment of microbes and the synthesis and accumulation of biofilm on the surface of the medical device. Also disclosed are methods of manufacturing such devices under conditions that substantially prevent preferential partitioning of any of said bioactive agents to a surface of the biocompatible matrix polymer and substantially prevent chemical modification of said bioactive agents

10. 发明授权

US08124876B2 Flexible device shaft with angled spiral wrap 有权
标题翻译：柔性装置轴带有螺旋形卷曲
公开(公告)号：US08124876B2
公开(公告)日：2012-02-28
申请号：US12546599
申请日：2009-08-24
申请人： Peter L. Dayton , Michael P. Boutillette
发明人： Peter L. Dayton , Michael P. Boutillette
IPC分类号： H01B7/17
CPC分类号： A61M25/0043 , A61B1/00071 , A61B1/0055 , A61M25/0013 , Y10T29/49995
摘要： Spiral-wound materials, spirals, and shafts made therefrom that have wraps with edges that may nest within one another are described. Such edges allow the spiral to achieve a smaller bending radius, meaning tighter turns and more flexibility due to the ability of adjacent wraps to nest within each other when the shaft is bent. Spirals having wraps with edges capable of nesting can be used in the medical field for devices that track anatomy, such as endoscopes, colonoscopes, catheters, and the like.
摘要翻译：描述了螺旋缠绕材料，螺旋形和由其制成的轴，它们可以彼此嵌套的边缘包裹。这样的边缘允许螺旋获得较小的弯曲半径，这意味着由于当轴弯曲时相邻的缠绕层彼此嵌套的能力，意味着更紧的匝数和更大的柔性。具有能够嵌套的边缘的螺旋可以用于医疗领域用于追踪解剖结构的装置，例如内窥镜，结肠镜，导管等。

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