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1. 发明授权

US5849542A Primer extension mass spectroscopy nucleic acid sequencing method 失效
标题翻译：引物扩增质谱法核酸测序法
公开(公告)号：US5849542A
公开(公告)日：1998-12-15
申请号：US640920
申请日：1996-05-10
申请人： Michael Alan Reeve , Roland Paul Howe , Terek Schwarz
发明人： Michael Alan Reeve , Roland Paul Howe , Terek Schwarz
IPC分类号： G01N27/62 , C12N15/09 , C12P19/34 , C12Q1/68 , G01N23/00 , G01N27/64 , G01N33/50 , B01D59/44 , C07H21/04 , G06G7/58
CPC分类号： C12Q1/6872 , C12Q1/6874
摘要： A method of sequencing a target nucleic acid using primer extension mass spectroscopy to generate an observed mass spectrum, on which base calling cycles are carried out using calibrated inter-peak mass difference values such that: each called base allows mass calculation for the base-called peak in the observed mass spectrum; this calculated mass is then used as a further calibration point for subsequent rounds of base calling. A reaction mixture of all four base-specific chain extension nucleotides and four chain termination nucleotide analogues. A method of performing mass spectroscopy, which method comprises subjecting molecular ions which have been chemically charged in a predetermined manner to time-of-flight or Fourier transform mass spectroscopy.
摘要翻译： PCT No.PCT / GB94 / 02527 Sec。 371日期：1996年5月10日 102（e）日期1996年5月10日PCT 1994年11月17日PCT PCT。公开号WO95 / 14108 日期1995年5月26日使用引物延伸质谱法测序靶核酸以产生观察质谱的方法，使用校准的峰间质量差值进行碱基调用循环，使得每个称为碱基允许质量计算观测质谱中称为基峰; 然后将该计算质量用作下一轮基地呼叫的另一校准点。所有四个碱基特异性链延伸核苷酸和四个链终止核苷酸类似物的反应混合物。一种执行质谱法的方法，该方法包括以已知化学方式对分子离子进行飞行时间或傅里叶变换质谱。

2. 发明授权

US07805339B2 Systems and methods for facilitating internet shopping 有权
标题翻译：促进互联网购物的系统和方法
公开(公告)号：US07805339B2
公开(公告)日：2010-09-28
申请号：US10324621
申请日：2002-12-18
申请人： Amir Ashkenazi , Oren Glickman , Paul Howe
发明人： Amir Ashkenazi , Oren Glickman , Paul Howe
IPC分类号： G06F17/30
CPC分类号： H05K7/2089 , G06Q10/087 , G06Q30/02 , G06Q30/0256 , G06Q30/0627 , G06Q30/0629 , G06Q30/0641 , H02M7/003
摘要： Systems and methods for facilitating online comparison shopping, including a similarity engine, a navigational system, and a step skipping system. The systems and methods according to the invention include a method for determining similarity between two preferably disparate products. The systems and methods also preferably include a method of increasing efficiency of navigation in a comparison shopping site based on product coverage and product entropy. The systems and methods further include a method of step-skipping to quicken user navigation through a comparison shopping site.
摘要翻译：用于促进在线比较购物的系统和方法，包括相似引擎，导航系统和步骤跳过系统。根据本发明的系统和方法包括用于确定两个优选不同产品之间的相似性的方法。系统和方法还优选地包括基于产品覆盖和产品熵来提高比较购物站点中的导航效率的方法。系统和方法还包括一种跳过方法，以加快用户通过比较购物站点的导航。

3. 发明授权

US06731694B2 Isolator eliminator for a linear transmitter 失效
标题翻译：用于线性变送器的隔离器消除器
公开(公告)号：US06731694B2
公开(公告)日：2004-05-04
申请号：US09924051
申请日：2001-08-07
申请人： John Janos Bozeki , Michael Howard Baker , Paul Howe Gailus , David H. Minasi
发明人： John Janos Bozeki , Michael Howard Baker , Paul Howe Gailus , David H. Minasi
IPC分类号： H04L2549
CPC分类号： H04L27/368
摘要： An isolator eliminator for a linear transmitter receives a plurality of digital samples of an information signal and a drive signal sampled from a feedback loop at periodic time intervals and, responsive to processing the digital samples, provides high accuracy phase and level correction signals to the feedback loop. The phase and level correction signals maintain stable, linear operation of the feedback loop and limit splatter. In a preferred embodiment, the isolator eliminator includes a digital signal processor such that multiple communication protocols may be accommodated by changing software code executed by the processor.
摘要翻译：用于线性发射器的隔离器消除器以周期性时间间隔接收信号信号和从反馈回路采样的驱动信号的多个数字样本，并且响应于处理数字样本，向反馈提供高精度的相位和电平校正信号循环。相位和电平校正信号保持反馈回路的稳定，线性运行并限制飞溅。在优选实施例中，隔离器消除器包括数字信号处理器，使得可以通过改变由处理器执行的软件代码来容纳多个通信协议。

4. 发明申请

US20130179305A1 SYSTEMS AND METHODS FOR FACILITATING INTERNET SHOPPING 审中-公开
标题翻译：促进互联网购物的系统和方法
公开(公告)号：US20130179305A1
公开(公告)日：2013-07-11
申请号：US13398685
申请日：2012-02-16
申请人： Amir Ashkenazi , Oren Glickman , Paul Howe
发明人： Amir Ashkenazi , Oren Glickman , Paul Howe
IPC分类号： G06Q30/06
CPC分类号： H05K7/2089 , G06Q10/087 , G06Q30/02 , G06Q30/0256 , G06Q30/0627 , G06Q30/0629 , G06Q30/0641 , H02M7/003
摘要： As part of the general search functionality in the context of a comparison shopping site, a skip by popularity functionality evaluates each keyword submitted to a search engine. The skip by popularity functionality then determines whether the keyword or keywords submitted are highly relevant to a specific attribute or category. When a relevance threshold with respect to a specific attribute or category is met, certain criteria may be applied to test whether the user can be skipped over intermediate navigational steps and immediately delivered to the highly relevant category or attribute or even to a comparison shopping page for a specific product. Skip by popularity functionality may be used to determine and select the single most popular product associated with the keyword as determined either by users, or according to some other suitable determination scheme.
摘要翻译：作为比较购物网站上下文中的一般搜索功能的一部分，按人气功能跳过来评估提交给搜索引擎的每个关键字。然后，通过受欢迎功能的跳过来确定所提交的关键字或关键字是否与特定属性或类别高度相关。当满足特定属性或类别的相关性阈值时，可以应用某些标准来测试用户是否可以在中间导航步骤上跳过并且立即传递到高度相关的类别或属性，或者甚至到达比较购物页面一个具体的产品。流行度功能的跳过可以用于确定和选择与由用户确定的关键字相关联的单个最受欢迎的产品，或者根据一些其他合适的确定方案。

5. 发明授权

US08140408B2 Systems and methods for facilitating internet shopping 有权
标题翻译：促进互联网购物的系统和方法
公开(公告)号：US08140408B2
公开(公告)日：2012-03-20
申请号：US11686061
申请日：2007-03-14
申请人： Amir Ashkenazi , Oren Glickman , Paul Howe
发明人： Amir Ashkenazi , Oren Glickman , Paul Howe
IPC分类号： G06Q30/00
CPC分类号： H05K7/2089 , G06Q10/087 , G06Q30/02 , G06Q30/0256 , G06Q30/0627 , G06Q30/0629 , G06Q30/0641 , H02M7/003
摘要： Systems and methods for facilitating online comparison shopping, including a similarity engine, a navigational system, and a step skipping system. The systems and methods according to the invention include a method for determining similarity between two preferably disparate products. The systems and methods also preferably include a method of increasing efficiency of navigation in a comparison shopping site based on product coverage and product entropy. The systems and methods further include a method of step-skipping to quicken user navigation through a comparison shopping site.
摘要翻译：用于促进在线比较购物的系统和方法，包括相似引擎，导航系统和步骤跳过系统。根据本发明的系统和方法包括用于确定两个优选不同产品之间的相似性的方法。系统和方法还优选地包括基于产品覆盖和产品熵来提高比较购物站点中的导航效率的方法。系统和方法还包括一种跳过方法，以加快用户通过比较购物站点的导航。

6. 外观设计

USD654143S1 Fishing lure 有权
公开(公告)号：USD654143S1
公开(公告)日：2012-02-14
申请号：US29394876
申请日：2011-06-22
申请人： Paul Howe
设计人： Paul Howe

7. 发明申请

US20110296738A1 FISHING LURE 审中-公开
标题翻译：钓鱼场
公开(公告)号：US20110296738A1
公开(公告)日：2011-12-08
申请号：US13154042
申请日：2011-06-06
申请人： Paul HOWE
发明人： Paul HOWE
IPC分类号： A01K85/00 , A01K99/00
CPC分类号： A01K85/00
摘要： The fishing jig includes a plurality of head members, at least a connection region connecting head members adjacent thereto, at least a hook member having a hook shank, a bend connected to a first end of the hook shank and a point adjacent to the bend, and an eyelet. The hook shank is at least partially embedded in the connection region or embedded in a head member. The head members that are adjacent to the connection region are substantially symmetrical relative to the connection region.
摘要翻译：钓鱼夹具包括多个头部构件，至少连接头部构件的连接区域，至少一个具有钩柄的钩构件，连接到钩柄的第一端的弯曲部和与弯曲部相邻的点，和孔眼。钩柄至少部分地嵌入在连接区域中或嵌入头部构件中。与连接区域相邻的头部构件相对于连接区域基本对称。

8. 发明申请

US20070156678A1 Systems and Methods for Facilitating Internet Shopping 有权
标题翻译：促进互联网购物的系统和方法
公开(公告)号：US20070156678A1
公开(公告)日：2007-07-05
申请号：US11686061
申请日：2007-03-14
申请人： Amir Ashkenazi , Oren Glickman , Paul Howe
发明人： Amir Ashkenazi , Oren Glickman , Paul Howe
IPC分类号： G06F17/30
CPC分类号： H05K7/2089 , G06Q10/087 , G06Q30/02 , G06Q30/0256 , G06Q30/0627 , G06Q30/0629 , G06Q30/0641 , H02M7/003
摘要： Systems and methods for facilitating online comparison shopping, including a similarity engine, a navigational system, and a step skipping system. The systems and methods according to the invention include a method for determining similarity between two preferably disparate products. The systems and methods also preferably include a method of increasing efficiency of navigation in a comparison shopping site based on product coverage and product entropy. The systems and methods further include a method of step-skipping to quicken user navigation through a comparison shopping site.
摘要翻译：用于促进在线比较购物的系统和方法，包括相似引擎，导航系统和步骤跳过系统。根据本发明的系统和方法包括用于确定两个优选不同产品之间的相似性的方法。系统和方法还优选地包括基于产品覆盖和产品熵来提高比较购物站点中的导航效率的方法。系统和方法还包括一种跳过方法，以加快用户通过比较购物站点的导航。

9. 发明申请

US20070074441A1 Rear CQB Sight and System 审中-公开
标题翻译：后CQB视力与系统
公开(公告)号：US20070074441A1
公开(公告)日：2007-04-05
申请号：US11464180
申请日：2006-08-11
申请人： Paul Howe
发明人： Paul Howe
IPC分类号： F41G1/00
CPC分类号： F41G1/01
摘要： The present invention is a rear sight for a firearm that is usable for both Close Quarters Combat (“CQB”) and standard shooting scenarios. The invention features both a primary targeting aperture and a CQB “notch”, both for use in conjunction with a standard sighting bead for the desired effects. The larger notch allows a greater field of view and raises the weapon slightly in comparison with the regular targeting aperture, thus making its use more efficient for CQB situations.
摘要翻译：本发明是可用于近距离战斗（“CQB”）和标准拍摄场景的枪支的后视。本发明具有主要瞄准孔和CQB“凹口”，两者均与用于期望效果的标准瞄准珠结合使用。较大的切口允许更大的视野，并与常规瞄准孔相比稍微提高武器，从而使其使用对CQB情况更有效。

10. 发明授权

US5976369A Magnetic separation apparatus 失效
标题翻译：磁选机
公开(公告)号：US5976369A
公开(公告)日：1999-11-02
申请号：US53732
申请日：1998-04-02
申请人： Roland Paul Howe , Michael Alan Reeve , Daniel Bischof
发明人： Roland Paul Howe , Michael Alan Reeve , Daniel Bischof
IPC分类号： B03C1/035 , B03C1/28 , G01N33/543 , G01N35/00 , B01D35/06
CPC分类号： G01N33/54326 , B03C1/035 , B03C1/288 , G01N35/0098
摘要： Biological assay systems often involve suspending magnetically attractable particles in a liquid, and later bringing down the particles from suspension and separating the formed pellet from the supernatant liquid. The invention provides magnetic systems for this purpose, shaped to form an annular or part-annular pellet close to the bottom of the vessel. The systems are suitable for automation.
摘要翻译：生物测定系统通常包括将可吸引的磁性颗粒悬浮在液体中，然后将悬浮液中的颗粒从上清液中分离出来并将上清液分离。本发明提供了用于此目的的磁性系统，其被成形为形成靠近容器底部的环形或部分环形颗粒。该系统适用于自动化。

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