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1. 发明授权

US08880356B2 Method and system for spectrum data analysis 有权
标题翻译：频谱数据分析方法与系统
公开(公告)号：US08880356B2
公开(公告)日：2014-11-04
申请号：US12866697
申请日：2009-02-06
申请人： Daniel Roy Corbett , Paul Gottlieb , Andrew Harley Menzies , Michael James Owen
发明人： Daniel Roy Corbett , Paul Gottlieb , Andrew Harley Menzies , Michael James Owen
IPC分类号： G01N23/00 , G01N23/207 , H01J37/28
CPC分类号： G01N23/2076 , H01J37/28
摘要： A method and system for spectrum data analysis. The method comprises the steps of collecting a spectrum of an unknown material; providing a set of data templates; calculating weighting factors for the element data templates to minimize error in approximating the spectrum; removing one or more of the templates having negative weights in approximating the spectrum; and re-calculating an approximation of the spectrum with said one or more templates removed. Embodiments of the invention are suitable for analyzing noisy spectra having relatively few data points.
摘要翻译：一种用于频谱数据分析的方法和系统。该方法包括收集未知材料的光谱的步骤; 提供一组数据模板; 计算元素数据模板的加权因子以最小化近似光谱的误差; 在近似光谱中去除具有负权重的一个或多个模板; 并且重新计算所述一个或多个模板移除的频谱的近似值。本发明的实施例适用于分析具有相对较少数据点的噪声谱。

2. 发明申请

US20090306906A1 METHOD AND SYSTEM FOR SPECTROSCOPIC DATA ANALYSIS 有权
标题翻译：用于光谱数据分析的方法和系统
公开(公告)号：US20090306906A1
公开(公告)日：2009-12-10
申请号：US12368176
申请日：2009-02-09
申请人： Paul Gottlieb , Michael Barnes , Brian William Bourke
发明人： Paul Gottlieb , Michael Barnes , Brian William Bourke
IPC分类号： G01N31/00 , G01N23/00
CPC分类号： G01N23/2206 , G01N23/2252 , H01J2237/2561
摘要： A method of analyzing spectroscopic data, the method comprising collecting spatially resolved measurement spectroscopic data of a sample for a series of measurements spots, assigning the measurement spots into a predefined set of spectral categories, based on characteristics of the spectroscopic data of the respective measurement spots, identifying groupings of the measurement spots based on their respective spectral categories and their spatial relationships, and assigning each grouping of measurement spots to a fundamental sample unit data object.
摘要翻译：一种分析光谱数据的方法，所述方法包括：基于各个测量点的光谱数据的特性，将用于一系列测量点的样本的空间分辨的测量光谱数据收集到预定义的光谱类别组中基于它们各自的光谱类别及其空间关系来识别测量点的分组，以及将每个测量点分组分配给基本采样单元数据对象。

3. 发明授权

US07979217B2 Method and system for spectroscopic data analysis 有权
标题翻译：光谱数据分析方法与系统
公开(公告)号：US07979217B2
公开(公告)日：2011-07-12
申请号：US12368176
申请日：2009-02-09
申请人： Paul Gottlieb , Michael Barnes , Brian William Bourke
发明人： Paul Gottlieb , Michael Barnes , Brian William Bourke
IPC分类号： G01N31/00 , G01N23/00 , G06F19/00
CPC分类号： G01N23/2206 , G01N23/2252 , H01J2237/2561
摘要： A method of analyzing spectroscopic data, the method comprising collecting spatially resolved measurement spectroscopic data of a sample for a series of measurements spots, assigning the measurement spots into a predefined set of spectral categories, based on characteristics of the spectroscopic data of the respective measurement spots, identifying groupings of the measurement spots based on their respective spectral categories and their spatial relationships, and assigning each grouping of measurement spots to a fundamental sample unit data object.
摘要翻译：一种分析光谱数据的方法，所述方法包括：基于各个测量点的光谱数据的特性，将用于一系列测量点的样本的空间分辨测量分光数据收集到预定义的光谱类别集合中; 基于它们各自的光谱类别及其空间关系识别测量点的分组，以及将每个测量点分组分配给基本采样单元数据对象。

4. 发明申请

US20140048972A1 Automated Sample Preparation 审中-公开
标题翻译：自动样品制备
公开(公告)号：US20140048972A1
公开(公告)日：2014-02-20
申请号：US14110576
申请日：2012-04-23
申请人： Paul Gottlieb
发明人： Paul Gottlieb
IPC分类号： G01N1/28
CPC分类号： G01N1/28 , G01N1/06 , G01N1/286 , G01N1/36 , H01J2237/2007 , H01J2237/201
摘要： Mineral samples for use in analytical instruments are created by a system that greatly reduces the sample preparation time and facilitates automation. For example, in some implementations, rather than grinding to expose the interior of mineral particles in sample plug containing mineral particles in an epoxy compound, the sample plug is sliced with a saw, which more rapidly provides in many applications a sufficiently smooth surface on the exposed particle surfaces for observation. Rather than slowly mixing a slow curing epoxy to avoid introducing bubbles into the sample plug, some implementations use a fast settle fixative and a mechanical mixture that avoid bubbles.
摘要翻译：用于分析仪器的矿物样品由大大降低样品准备时间并便于自动化的系统创建。例如，在一些实施方案中，不是研磨以暴露含有环氧化合物中的矿物颗粒的样品塞中的矿物颗粒的内部，用锯切片样品塞，其在许多应用中更快地提供足够光滑的表面暴露的颗粒表面进行观察。不是缓慢地混合缓慢固化的环氧树脂，以避免将气泡引入到样品塞中，一些实施方案使用快速沉降固定剂和避免气泡的机械混合物。

5. 发明申请

US20110144922A1 Method and System for Spectrum Data Analysis 有权
标题翻译：频谱数据分析方法与系统
公开(公告)号：US20110144922A1
公开(公告)日：2011-06-16
申请号：US12866697
申请日：2009-02-06
申请人： Daniel Roy Corbett , Paul Gottlieb , Michael James Owen , Andrew Harley Menzies
发明人： Daniel Roy Corbett , Paul Gottlieb , Michael James Owen , Andrew Harley Menzies
IPC分类号： G01N23/00 , G06F19/00
CPC分类号： G01N23/2076 , H01J37/28
摘要： A method and system for spectrum data analysis. The method comprises the steps of collecting a spectrum of an unknown material; providing a set of data templates; calculating weighting factors for the element data templates to minimize error in approximating the spectrum; removing one or more of the templates having negative weights in approximating the spectrum; and re-calculating an approximation of the spectrum with said one or more templates removed. Embodiments of the invention are suitable for analyzing noisy spectra having relatively few data points.
摘要翻译：一种用于频谱数据分析的方法和系统。该方法包括收集未知材料的光谱的步骤; 提供一组数据模板; 计算元素数据模板的加权因子以最小化近似光谱的误差; 在近似光谱中去除具有负权重的一个或多个模板; 并且重新计算所述一个或多个模板移除的频谱的近似值。本发明的实施例适用于分析具有相对较少数据点的噪声谱。

6. 发明授权

US5912241A Methods of use of phthalocyanines to inactivate blood borne parasites 失效
标题翻译：使用酞菁灭活血液寄生虫的方法
公开(公告)号：US5912241A
公开(公告)日：1999-06-15
申请号：US971835
申请日：1997-11-17
申请人： Paul Gottlieb , Ehud Ben-Hur , Sara Lustigman
发明人： Paul Gottlieb , Ehud Ben-Hur , Sara Lustigman
IPC分类号： A61K31/40 , A61K31/409 , A61K31/555 , A61K38/06 , A61K41/00 , A61L2/00
CPC分类号： A61K31/7004 , A61K31/40 , A61K31/409 , A61K31/555 , A61K38/06 , A61K38/063 , A61K41/0014 , A61K41/0019 , A61K41/0071 , A61L2/0011 , A61L2/0088
摘要： This invention relates to a method for inactivating parasites in blood cell-containing compositions by incubating a mixture of the blood cell-containing composition, a phthalocyanine dye and a quencher and optionally irradiating this mixture with red light. This invention further relates to a method of sterilizing blood cell-containing compositions which contain lipid enveloped viruses and blood borne parasites.
摘要翻译：本发明涉及通过将含血液细胞的组合物，酞菁染料和猝灭剂的混合物孵育并任选地用红光照射该混合物来灭活含有血细胞的组合物中的寄生虫的方法。本发明还涉及含有含脂质包膜病毒和血传播寄生虫的含血细胞的组合物的灭菌方法。

7. 发明申请

US20110301869A1 Method and System for Spectroscopic Data Analysis 有权
标题翻译：光谱数据分析方法与系统
公开(公告)号：US20110301869A1
公开(公告)日：2011-12-08
申请号：US13153914
申请日：2011-06-06
申请人： Paul Gottlieb , Michael Barnes , Brian William Bourke
发明人： Paul Gottlieb , Michael Barnes , Brian William Bourke
IPC分类号： G06F19/00 , G01N23/00
CPC分类号： G01N23/2206 , G01N23/2252 , H01J2237/2561
摘要： A method of analyzing spectroscopic data, the method comprising collecting spatially resolved measurement spectroscopic data of a sample for a series of measurements spots, assigning the measurement spots into a predefined set of spectral categories, based on characteristics of the spectroscopic data of the respective measurement spots, identifying groupings of the measurement spots based on their respective spectral categories and their spatial relationships, and assigning each grouping of measurement spots to a fundamental sample unit data object.
摘要翻译：一种分析光谱数据的方法，所述方法包括：基于各个测量点的光谱数据的特性，将用于一系列测量点的样本的空间分辨测量分光数据收集到预定义的光谱类别集合中; 基于它们各自的光谱类别及其空间关系识别测量点的分组，以及将每个测量点分组分配给基本采样单元数据对象。

8. 发明授权

US07490009B2 Method and system for spectroscopic data analysis 有权
标题翻译：光谱数据分析方法与系统
公开(公告)号：US07490009B2
公开(公告)日：2009-02-10
申请号：US10911057
申请日：2004-08-03
申请人： Paul Gottlieb , Michael Barnes , Brian William Bourke
发明人： Paul Gottlieb , Michael Barnes , Brian William Bourke
IPC分类号： G01N31/00 , G01N23/00 , G06F19/00
CPC分类号： G01N23/2206 , G01N23/2252 , H01J2237/2561
摘要： A method of analyzing spectroscopic data, the method comprising collecting spatially resolved measurement spectroscopic data of a sample for a series of measurements spots, assigning the measurement spots into a predefined set of spectral categories, based on characteristics of the spectroscopic data of the respective measurement spots, identifying groupings of the measurement spots based on their respective spectral categories and their spatial relationships, and assigning each grouping of measurement spots to a fundamental sample unit data object.
摘要翻译：一种分析光谱数据的方法，所述方法包括：基于各个测量点的光谱数据的特性，将用于一系列测量点的样本的空间分辨测量分光数据收集到预定义的光谱类别集合中; 基于它们各自的光谱类别及其空间关系识别测量点的分组，以及将每个测量点分组分配给基本采样单元数据对象。

9. 发明申请

US20060028643A1 Method and system for spectroscopic data analysis 有权
标题翻译：光谱数据分析方法与系统
公开(公告)号：US20060028643A1
公开(公告)日：2006-02-09
申请号：US10911057
申请日：2004-08-03
申请人： Paul Gottlieb , Michael Barnes , Brian Bourke
发明人： Paul Gottlieb , Michael Barnes , Brian Bourke
IPC分类号： G01J3/00
CPC分类号： G01N23/2206 , G01N23/2252 , H01J2237/2561
摘要： A method of analysing spectroscopic data, the method comprising collecting spatially resolved measurement spectroscopic data of a sample for a series of measurements spots, assigning the measurement spots into a predefined set of spectral categories, based on characteristics of the spectroscopic data of the respective measurement spots, identifying groupings of the measurement spots based on their respective spectral categories and their spatial relationships, and assigning each grouping of measurement spots to a fundamental sample unit data object.
摘要翻译：一种分析光谱数据的方法，所述方法包括：基于各个测量点的光谱数据的特性，将用于一系列测量点的样本的空间分辨测量分光数据收集到预定义的光谱类别集合中; 基于它们各自的光谱类别及其空间关系识别测量点的分组，以及将每个测量点分组分配给基本采样单元数据对象。

10. 发明授权

US5985331A Methods of use of phthalocyanines to inactivate blood borne parasites 失效
标题翻译：使用酞菁灭活血液寄生虫的方法
公开(公告)号：US5985331A
公开(公告)日：1999-11-16
申请号：US952593
申请日：1998-06-05
申请人： Paul Gottlieb , Ehud Ben-Hur , Sara Lustigman
发明人： Paul Gottlieb , Ehud Ben-Hur , Sara Lustigman
IPC分类号： A61K31/40 , A61K31/409 , A61K31/555 , A61K38/06 , A61K41/00 , A61L2/00 , A61K35/14 , A61K35/18 , C12N13/00
CPC分类号： A61K31/7004 , A61K31/40 , A61K31/409 , A61K31/555 , A61K38/06 , A61K38/063 , A61K41/0014 , A61K41/0019 , A61K41/0071 , A61L2/0011 , A61L2/0088
摘要： This invention relates to a method for inactivating parasites in blood cell-containing compositions by incubating a mixture of the blood cell-containing composition, a phthalocyanine dye and a quencher and optionally irradiating this mixture with red light. This invention further relates to a method of sterilizing blood cell-containing compositions which contain lipid enveloped viruses and blood borne parasites.
摘要翻译： PCT No.PCT / US96 / 06787 Sec。 371日期：1998年6月5日 102（e）日期1998年6月5日PCT提交1996年5月14日PCT公布。出版物WO96 / 36704 日本特开1996年11月21日本发明涉及通过将含血细胞的组合物，酞菁染料和猝灭剂的混合物温育并任选用红光照射该混合物来灭活含有血细胞的组合物中的寄生虫的方法。本发明还涉及含有含脂质包膜病毒和血传播寄生虫的含血细胞的组合物的灭菌方法。

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